Source: COVID-19 Immunophenotyping Jul 19, 2020 3 years ago
COVID-19 Immunophenotyping: A major of the sign of SARS-CoV-2 infection is the broad-spectrum of disease severity. COVID-19 usually results in a mild disease course that resolves on its own. However, about 8 to 12% of patients develop severe symptoms that require intensive care with mechanical ventilation. Understanding this distinction, and uncovering the cause of the difference between mild dise...
COVID-19 Drugs: Iran is one of the worse hit countries by the COVID-19 crisis and initially as a result of drug shortages and misinformation, Iranian physicians were using hydroxychloroquine (HCQ) to treat many of its patients but as the lethal effects of the drug became known, many local researchers turned to drug-repurposing studies to find alternatives.
One such identified drug was Febuxostat....
Source: COVID-19 Supplements Jul 19, 2020 3 years ago
COVID-19 Supplements: Scientists from the Wuhan University of Bioengineering in China say that curcumin, a natural compound found in the spice turmeric, could help eliminate certain coronaviruses especially an alpha-group coronavirus that infects pigs.
The new research in China showed that curcumin can prevent transmissible gastroenteritis virus (TGEV), an alpha-group coronavirus that inf...
Source: COVID-19 Research Jul 19, 2020 3 years ago
COVID-19 Research: Researchers from Cleveland Clinic and Case Western Reserve University have identified genetic factors that may influence susceptibility to COVID-19.
These findings could pave the way for a personalized medicine approach for treating COVID-19 as it is emerging more day by day that COVID-19 is a highly complex disease with different pathogenesis paths in different i...
COVID-19 Updates: A study by German And Swedish researchers suggest that statins do not aggravate the risk of COVID-19 infection rather on the contrary may have some beneficial effect in some cases as they could reduce and even inhibit SARS-CoV-2 coronavirus entry into the cells of the human host.
The study findings were published on a preprint server and is yet to have been peer-reviewed. https:...
Source: COVID-19 Research Jul 18, 2020 3 years ago
COVID-19 Research: A new report by researchers from John Hopkins University School of Medicine suggests an infusion of cells that dampen the body's immune response might help individuals with severe cases of the new coronavirus recover more quickly.
In the report, two patients so sick with COVID-19 that they'd been put on a ventilator improved quickly when given an infusion of reg...
Source: India COVID-19 News Jul 18, 2020 3 years ago
India COVID-19 News: The COVID-19 situation in India is totally grim as epidemiological modeling experts and medical researchers from Bengaluru are claiming that reported figures are not the least accurate as India does not have a proper reporting structure in place coupled with the fact that state governments are trying to conceal the actual impact of the crisis and also hospitals and doctors do ...
Source: COVID-19 Diagnostics Jul 18, 2020 3 years ago
COVID-19 Diagnostics: Roughly between 8 to 12% of individuals with COVID-19 disease progresses to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome.
Although these forms sometimes occur early in the course of the disease, clinical observations generally describe a two-stage progression of the disease, beginning ...
COVID-19 Drugs: Dexamethasone’s much-awaited official results from a UK trial of the steroid dexamethasone were published finally a few hours ago in the New England Journal of Medicine, confirming its life-saving benefits for COVID-19 patients on ventilators but suggesting it may cause harm if given too early. https://www.nejm.org/doi/full/10.1056/NEJMoa2021436?query=featured_home
In...
COVID-19 Latest: Researchers from the University of California-Berkeley say that some individuals could be infected by two strain variations of the SARS-CoV-2 coronavirus at once, sending the immune system into overdrive. Such cases are also emerging globally with scientist warning that co-infections with two or more different strains could even render vaccines, antibodies and current drug protoco...
Men’s Health: Thailand Medical News was overjoyed when we received this study report as the past few weeks were depressed after reading a report that said the most porn sites made up to 480 per cent increase in revenue the last few months during the COVID-19 crisis and their viewership grew while struggling medical websites like ours were desperate to even get one or two donations a month to...
Source: Reproductive Medicine & Male Fertility Jul 17, 2020 3 years ago
Reproductive Medicine: Infertility affects 12% to 18% of couples globally, and while it has often viewed as a women’s health problem, men actually contribute to around half of the cases. Male infertility is on the increase unknown to many due to a variety of reasons and causes.
A new male fertility test based on Cornell research could help predict which men might need treatment and which ...
COVID-19 News: Scientists from the Montreal Neurological Institute, McGill University have discovered that the SARS-CoV-2 may be using a unique method of clathrin-mediated endocytosis to gain entry into the host cells.
The research findings are published on a preprint server and are pending peer review.
https://www.biorxiv.org/content/10.1101/2020.07.13.201509v2
The Canadian researc...
COVID-19 Vaccine: Moderna has announced that said its COVID-19 vaccine candidate mRNA-1273 will advance to a 30,000-participant Phase III trial later this month, following publication of additional positive Phase I data from a study led by the NIH’s National Institute of Allergy and Infectious Diseases (NIAID).
The “COVE” Phase III study (NCT04470427) is expected to begin regis...
Source: COVID-19 Diagnostics Jul 17, 2020 3 years ago
COVID-19 Diagnostics: Researchers from Coney Island Hospital-New York in a new study have found that a simple rapid laboratory test, the eosinophil count, readily obtained from a routine complete blood cell count (CBC) can aid in the early recognition of COVID-19 in patients, as well as provide prognostic information.
Their research findings have been published in The Journal of the Ameri...
Source: COVID-19 Supplements Jul 17, 2020 3 years ago
COVID-19 Supplements: Medical researchers from University of California-Los Angeles, Beijing University and also Jinan University in Guangdong- China have discovered that a new stabilized nano-capsulized drug based on the antioxidant enzyme catalase could play a vital part in reducing the inflammation associated with progressive and severe COVID-19 disease.
The research findings have been...
Medical Devices For COVID-19: Northwestern University Researchers together with Shirley Ryan AbilityLab have developed a new wearable medical device for continuous monitoring of COVID -19 patients after having conducted a study of existing consumer devices and other medical device wearables and found limitations in these devices.
Credit: Northwestern University
The new extremely sticker l...
COVID-19 Vaccine Updates: Data from the Phase 1 trial of COVID-19 vaccine by AstraZeneca and Oxford University’s Jenner Institute is showing a robust defense against the novel coronavirus that has infected more than 13.6 million individuals across the globe
U.K. media yesterday began to report hints of data from the early-stage study of the vaccine candidate...
Source: COVID-19 Research Jul 17, 2020 3 years ago
COVID-19 Research: According to emerging research reports from New York, COVID-19 is associated with life-threatening blood clots in the arteries of the legs.
Researchers are saying that COVID-19 patients with symptoms of inadequate blood supply to the lower extremities tend to have larger clots and a significantly higher rate of amputation and death than uninfected individuals with the same con...
COVID-19 News: Cannabidiol or CBD, may help reduce the cytokine storm and excessive lung inflammation that is killing many patients with COVID-19, researchers say.
Though more work, including clinical trials to determine optimal dosage and timing, is needed before CBD becomes part of the treatment for COVID-19, researchers at the Dental College of Georgia and Medical College of ...
Source: U.S. COVID-19 News Jul 16, 2020 3 years ago
U.S. COVID-19 News: The total number of official COVID-19 Infections in America is now 3.51 million and the total number of Americans who have died from the COVID-19 is 139,012 (almost coming to 140,000). It is reported that almost 1.64 million of those infected have ‘recovered’ while about 27,213 are in critical conditions throughout the country.
The US CDC had earlier said t...
COVID-19 Spread: Smart and cautious individuals are now avoiding the public toilets or restrooms and suddenly, portable camping potties and female funnels have become must-have products, selling out at camping stores and back-ordered online nationwide in America.
Melissa Paul, a merchandising manager at REI, where sales of the Luggable Loo and Go Anywhere portable toilets ...
Source: COVID-19 Immune Response Jul 16, 2020 3 years ago
COVID-19 Immune Response: Scientists from the Penn Institute of Immunology-University of Pennsylvania have discovered three distinct immune responses to the SARS-CoV2 infection that could help predict the trajectory of disease in severe COVID-19 patients and may ultimately inform how to best treat them.
Senior author Dr E. John Wherry, Ph.D., chair of the department of Systems Pharmacolog...
Source: COVID-19 Immunology Jul 16, 2020 3 years ago
COVID-19 Immunology: Medical researchers from a Singapore study have uncovered the presence of virus-specific T cell immunity in individuals who recovered from COVID-19 and SARS, as well as some healthy study subjects who had never been infected by either virus.
The new findings from the research by scientists from Duke-NUS Medical School, in close collaboration with the National Universi...
Biotech Startups: Utah based biotech startup; IDbyDNA’s explify platform for metagenomics analysis is transforming highly sophisticated research-only laboratory tools into practical diagnostics tools for easy routine hospital use.
With the new platform, doctors can now determine not just whether a patient has COVID-19, but also in the same test whether that patient has other respira...
Source: COVID-19 Transmission Jul 16, 2020 3 years ago
COVID-19 Transmission: Forget about the stupid idea proposed about immunity passports. If this new research is confirmed as really true, then maybe every human on the planet might have to start wearing tags to show blood groups types they belong to with blood groups who can be super spreaders being isolated from the rest!
In this new modeling study led by Dr Peter Ellis from the&nbs...
COVID-19 Drugs: A research team led by Hebrew University of Jerusalem (HU)'s Professor Dr Yaakov Nahmias says that a simple and inexpensive cholesterol-lowering drug called Fenofibrate (Tricor) that is been approved and on the market for decades could help downgrade the severity of COVID-19 disease.
The early research finding which looks promising has been published in the preprint section of...
COVID-19 Drugs: Heparin, a common drug, already approved by the US as an anticoagulant may also be a powerful tool in fighting COVID-19, according to research published in the journal: Antiviral Research. https://www.sciencedirect.com/science/article/abs/pii/S0166354220302874?via%3Dihub
The SARS-CoV-2, the virus that causes COVID-19, uses a surface spike protein to latch onto human c...
Source: COVID-19 Symptoms Jul 16, 2020 3 years ago
COVID-19 Symptoms: Although various skin rashes and breakouts are already being associated with COVID-19 now doctors in Spain doctors are reporting that rashes on the inside of the mouth are also occurring in some cases.
The study findings reporting this new emerging clinical symptom is published in the latest edition of the journal: JAMA Dermatology (Journal Of The American Medical Assoc...
Source: COVID-19 Antibodies Jul 15, 2020 3 years ago
COVID-19 Antibodies: A new study by researchers from Netherlands warns against the use of any COVID-19 therapies containing the IgG antibodies as these would react with the macrophages in the bodies of the infected and accelerate cytokine storms.
Though these IgG antibodies are more prevalent in large amounts in patients with severe COVID-19 conditions, they are also found in very small a...
COVID-19 Vaccine: The Phase 1 trial of an investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes COVID-19 disease, was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to US NIH authorities.
The interim results of the trial were published yesterday in The New England Journal of Medicine....
Source: COVID-19 Heart Issues Jul 15, 2020 3 years ago
COVID-19 Heart Issues: To date more than 22% of all COVID-19-associated deaths are from cardiac complications, yet the mechanisms from which these complications arise have remained a topic of debate in the cardiology community.
One common hypothesis centers on the infection of the heart itself, but the understanding of which cells may be infected is unclear.
In order to address thi...
Source: COVID-19 Delirium Jul 15, 2020 3 years ago
COVID-19 Delirium: Trinity College Researchers in Dublin have identified a connection between aberrant energy metabolism in the brain and delirium ie the state of impaired cognition in individuals who are unwell. This mental symptom is proving common in individuals hospitalized with COVID-19.
The research findings were published in the peer-reviewed Journal of Neuroscience. https://w...
COVID-19 News: In a new detailed study conducted by researchers from the University Hospital of Salamanca in Spain that was funded by the Spanish Ministry For Science, in was found that more than 40 percent of 139 health care workers who had recovered from COVID-19 were found to have Pericarditis Or/And Myocarditis when they were examined about 10 weeks later. More than 42 % experienced symptoms a...
COVID-19 Rehab: As the number of confirmed global COVID-19 cases is fast approaching 14 million and many experts are saying that the numbers could actually be as high as 10 to 20 times that figure due to underreporting by many countries and also due to concealments in some cases, it is becoming apparent day by day and an emerging fact that there is a whole list of long term health complications ar...
COVID- 19 Vaccine: Canadian biophamaceutical company Medicago that is based in Quebec with branches in the U.S. announced that it has begun Phase I clinical trial for its plant-derived COVID-19 vaccine candidate. It has already administered the first doses of the candidate in healthy human subjects, and the company intends to initiate a Phase II/III trial this coming October.
Dr Nath...
COVID-19 Vaccine: American researchers from Duke University-Durham have made an important discovery about the spike protein SARS-CoV-2 that could have a broad impact on vaccine studies.
The S or spike protein is the structure that binds to host cell angiotensin-converting enzyme 2 (ACE2) to enable viral attachment and entry during the infection process. The spike protein is also...
Source: COVID-19 Research Jul 15, 2020 3 years ago
COVID-19 Research: According to an international study led by the University of Cincinnati College of Medicine, depressed mood or anxiety exhibited in COVID-19 patients may possibly be a sign that the SARS-CoV-2 coronavirus is affecting the central nervous system.
The research findings are published in the journal: Laryngoscope. https://onlinelibrary.wiley.com/doi/abs/10.1002/lary.28964
&...
Source: COVID-19 Research Jul 14, 2020 3 years ago
COVID-19 Research: Researchers from New York University Langone Health in a retrospective study, found that the viral load of SARS-CoV-2 collected from patients in the emergency department is significantly higher in patients with fewer or milder symptoms who did not require hospitalization, the opposite of what might be expected. They also found that a patient's history of cancer and cardiovas...
Source: COVID-19 Pandemic Jul 14, 2020 3 years ago
COVID-19 Pandemic: A modeling study by Imperial College London and Oxford University predicts that the global healthcare industry will be disrupted the next 5 years due to the COVID-19 pandemic and that there will be a huge surge in deaths for those who contract or are suffering from HIV, TB and Malaria.
Certain low- and middle-income countries (LMICs) could see HIV, tuber...
Source: COVID-19 Supplements-Zinc Jul 14, 2020 3 years ago
COVID-19 Supplements: It seems that certain doctors, (those unethical ones getting commissions from Pharma giants), fact checkers (those buffoons who failed in their careers and work as fact checkers for garbage companies like Facebook) and certain corrupted government authorities tend to have an affinity for always discounting the fact that vitamins, supplements and herbs could help in cert...
Source: SARS-CoV-2 Spike Protein Jul 14, 2020 3 years ago
SARS-CoV-2 Spike Protein: In most of the research concerning vaccine and antiviral development, the key target is the spike (S) protein of the SAR-CoV-2 coronavirus, a trimeric component of the viral particle that is responsible for binding to the host receptor, ie the angiotensin-converting enzyme 2 (ACE2).
A new research by scientists from Janssen Vaccines & Prevention B...
Source: COVID-19 Symptoms Jul 14, 2020 3 years ago
COVID-19 Symptoms: Medical researchers from King’s College London and Zoe Global Ltd have conducted a study suggesting that skin rashes could be valuable predictors of coronavirus disease 2019 (COVID-19).
The research finds are being peer-reviewed and are currently published on a preprint server. https://www.medrxiv.org/content/10.1101/2020.07.10.20150656v1
The large and deta...
COVID-19 Vaccine: There are more than 140 SARS-CoV-2 vaccines in development and the race for a successful candidate to help prevent COVID-19 is making many researchers jumpstart processes and in some cases even by pass safety protocols.
Although an effective and safe vaccine would be a major advance in the fight against COVID-19, there are challenges in evaluating the efficacy of&nb...
Source: COVID-19 Immunity Jul 14, 2020 3 years ago
COVID-19 Immunity: Researchers from King’s College London and Guy’s and St Thomas’ NHS Foundation Trust in a long and detailed study discovered that there is a rapid decline in the levels of SARS-CoV-2 neutralizing antibodies during the weeks following initial infection. This raises questions over the potential for re-infection, the effectiveness that may be expected from va...
Source: COVID-19 Antibodies Jul 13, 2020 3 years ago
COVID-19 Antibodies: A new research led Scripps Research Institute has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.
The researchers reviewed data on nearly 300 anti-SARS-CoV-2 antibodies that their labs and others have found in convalescent COVID-19 patients over the past few months....
COVID-19 Vaccine: Maryland based Altimmune, Inc., a clinical-stage biopharmaceutical company, has reported positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.
The research studies; a collaboration between the University of Alabama-Birmingham and Altimmune showed strong serum neutr...
Source: Thailand COVID-19 Jul 13, 2020 3 years ago
Thailand COVID-19: Thailand is reporting new COVID-19 cases from foreigners and Thais coming from Muslim countries like Pakistan, Egypt, UAE, Kuwait etc. Many local Thais are getting upset with the government for allowing flights to resume from these countries and are calling for a ban for all flights and arrivals from these countries.
In what is now becoming a major health scare that is ...
COVID-19 Drugs: A relatively large and detailed clinical trial performed by Japanese researchers has showed inconclusive data from Covid-19 patients treated with Fujifilm’s Avigan drug also known as favipiravir. Fujita Health University researcher Professor Dr Yohei Doi said that the drug led to improvement in patients treated early, compared to those who received delayed dose...
Source: China COVID-19 News Jul 13, 2020 3 years ago
China COVID-19 News: A prominent Chinese doctor from Renmin Hospital of Wuhan University who has been supplying us with research studies and information but on conditions of anonymity since the start of the outbreak has claimed to say that the situation in China is more dire that thought as he claims that millions of Chinese country wide are infected with the SARS-CoV-2 coronavirus but do no...
Source: COVID-19 Immunology Jul 13, 2020 3 years ago
COVID-19 Immunology: A new study by German researchers from Saarland University shows that there are higher levels of anti-SARS-CoV-2 T cells, which show significant alterations in the phenotype and function in COVID-19 patients.
Initial research had already shown that the SARS-CoV-2 coronavirus causes broad changes in cellular immune response, seen chiefly as lymphopenia, altera...
Source: COVID-19 Innovations Jul 13, 2020 3 years ago
COVID-19 Mask: Medical and Engineering Researchers from MIT and Harvard’s Brigham and Women’s Hospital have designed a new face mask that they believe could stop viral particles as effectively as N95 masks. Unlike N95 masks, the new masks were designed to be easily sterilized and used many times.
The masks are based on the shape of the 3M 1860 style of N95 masks, the type n...
Source: COVID-19 Cellular Therapy Jul 13, 2020 3 years ago
COVID-19 Cellular Therapy. Spanish researchers announced that a cellular therapy tested on 13 intubated patients with mechanical ventilation has shown to be efficient for the clinical improvement of critical cases of COVID-19.
The research which is the broadest published to date in these conditions, has been published in journal: The Lancet's EClinical Medicine, after proving that the...
Source: COVID-19 Research Jul 13, 2020 3 years ago
COVID-19 Research: Researchers from the department of molecular medicine at Scripps Research Institute - Florida in a new study have discovered that cholesterol saturation in host cells helps to facilitate viral entry of the SARS-CoV-2 coronavirus.
Their research findings were published on a preprint server but are yet to have been peer-reviewed. https://www.biorxiv.org/content/10.1101/20...
Hand Sanitizer Reaction: A report was published in the Oxford journal: Alcohol and Alcoholism in which a case study was highlighted involving Disulfiram-Ethanol reactions by hand-sanitizer usage. The case warn patients recovering from alcoholic addiction and are on the drug Disulfiram to be ware when using ethanol containing hand sanitizers. https://academic.oup.com/alcalc/article-abstract/55/4/34...
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