Nikhil Prasad Fact checked by:Thailand Medical News Team Dec 18, 2025 2 hours, 56 minutes ago
Medical News: Uncovering the Hidden Link
Imagine recovering from COVID-19, only to face ongoing fatigue, brain fog, or heart issues months later. That's long COVID, a puzzling condition affecting millions. Now, fresh research from experts at the Center for Molecular and Vascular Biology in Leuven, Belgium, McGill University in Montréal, Quebec, Canada, the University of Cambridge in Cambridge, UK, and the University of Oxford in Oxford, UK, shines a light on why this happens. The study team dove into human genetics to explore if blood clots play a key role.
Genes tied to blood clots boost long COVID risk by 21%, new study reveals.
What the Study Found
Using data from over 3,000 people with long COVID and nearly a million without, the team checked genetic risks for thromboembolism—basically, dangerous blood clots in veins. They discovered that folks with genes raising clot risk had about 21% higher chances of developing long COVID.
This link held strong even after accounting for how severe their initial COVID infection was. To double-check, they ran extra tests and confirmed the results in other groups. Digging deeper, they pinpointed a molecule called protease-activated receptor 1 (PAR-1) as a possible player, based on protein and gene data. It's like finding a shared pathway where clots and lingering COVID symptoms overlap.
Why This Matters
This isn't just theory; it's solid evidence from real human genes, not lab experiments. In this
Medical News report, we see how it challenges old ideas about long COVID being only from inflammation, adding clots to the mix for better treatments ahead.
Wrapping It Up
In conclusion, these findings strongly suggest that genetic factors increasing the risk of blood clots could be driving long COVID in people of European descent, paving the way for targeted therapies to prevent or ease these persistent symptoms that disrupt daily life for so many.
The study findings were published in the peer reviewed journal: Nature Cardiovascular Research.
https://www.nature.com/articles/s44161-025-00749-4
For the latest on Long COVID, keep on logging to Thailand
Medical News.
Read Also:
https://www.thailandmedical.news/articles/long-covid
https://www.thailandmedical.news/articles/coronavirus
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