BREAKING NEWS
Source: Ionicon Analytik Ges.m.b.H.  Mar 11, 2019  3 years ago
Over the last few years, a developing field of research has emerged in breath gas analysis of volatile organic compounds (VOCs). This technique is non-invasive and has a number of possible applications, including monitoring of metabolic processes, study of pharmacokinetics, screening for disease biomarkers and drug testing. Advantages of IONICON PTR-TOFMS The detection limits and linearity rang...
Source: American College Of Cardiology  Mar 11, 2019  3 years ago
There's now another reason to get your yearly flu shot. Not only can it protect you from the body aches, fever and fatigue associated with a bout of influenza, it may even prevent you from having a heart attack, according to research being presented at the American College of Cardiology's 68th Annual Scientific Session. The study of nearly 30 million hospital records shows that people who ...
Source: Conference on Retroviruses and Opportunistic Infections (CROI 2019) ,Seattle.  Mar 10, 2019  3 years ago
A combination of two long-acting injectable anti-HIV drugs taken once monthly had a very low rate of treatment failure and a favourable safety profile, according to results from two phase III trials presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2019) in Seattle.    Dual injections of cabotegravir, an experimental integrase inhibitor, and the no...
Source: Institute of Cancer Research, London  Mar 10, 2019  3 years ago
Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals. Scientists found that PARP inhibitors sparked a powerful immune response when used against cancer cells with weaknesses in repairing their DNA.   The study changes our understanding of how PARP inhibito...
Source: Columbia University, Irving Medical Center   Mar 10, 2019  3 years ago
Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum-- a common oral bacteria often implicated in tooth decay -- accelerates the growth of colon cancer.  The findings could make it easier to identify and treat more aggressive colon cancers. It also helps explain why some cases advance far more quickly than others, thanks to the same bacter...
Source: University Of Queensland  Mar 09, 2019  3 years ago
New details about the role of zinc in our immune system could help the development of new non-antibiotic treatment strategies for bacterial diseases, such as urinary tract infections (UTIs).   UTIs are one of the most common bacterial infections worldwide with about 150 million cases each year, and can lead to serious conditions such as kidney infection and sepsis. A team of cross-instit...
Source: Society for Healthcare Epidemiology of America  Mar 08, 2019  3 years ago
Prior antibiotic exposure and use of acid suppressing medications known as proton pump inhibitors (PPIs) may increase the risk for hospitalized children to contract dangerous Clostridioides difficile infections, according to a study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. Clostridioides d...
Source: University of Southern California  Mar 07, 2019  3 years ago
A diet containing compounds found in green tea and carrots reversed Alzheimer's-like symptoms in mice genetically programmed to develop the disease, USC researchers say. Researchers emphasize that the study, recently published in the Journal of Biological Chemistry, was in mice, and many mouse discoveries never translate into human treatments. Nevertheless, the findings lend credence to...
Source: Samitivej Hospitals  Mar 06, 2019  3 years ago
Samitivej Reaffirms Its Leadership in Mobile Health Innovations Samitivej is expanding its innovative mobile health services, based on the hospital’s deep understanding of patient needs. Samitivej Mobile Health offers Samitivej Plus app, Line@Samitivej and Samitivej PACE to improve the patient experience. Mobile Health is now also offering Ward Tracking application to assist patients in pre...
Source: University of Southern California  Mar 06, 2019  3 years ago
USC researchers provided evidence that a low-calorie "fasting-mimicking" diet has the potential to reduce inflammation and repair the gut. Published in a recent  edition of Cell Reports, the study reports on the health benefits of periodic cycles of the diet for people with inflammation and indicated that the diet reversed inflammatory bowel disease (IBD) patholo...
Source: Johns Hopkins University, Baltimore  Mar 05, 2019  3 years ago
Many Americans take a daily low-dose aspirin to protect their hearts. Now it appears aspirin may also reduce flare-ups of chronic obstructive pulmonary disease (COPD). In a study of COPD sufferers, researchers found that aspirin was linked to fewer moderate exacerbations, but not severe bouts, of the lung disease. It also reduced moderate and severe episodes of labored breathing. ...
Source: University of Luxembourg  Mar 04, 2019  3 years ago
Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg and from the German Cancer Research Center (DKFZ) have been able to rejuvenate stem cells in the brain of aging mice. The revitalised stem cells improve the regeneration of injured or diseased areas in the brain of old mice. The researchers expect that their approach will provide fresh impetus in r...
Source: Alphatec Inc, California  Mar 03, 2019  3 years ago
Alphatec Inc based in California, recently obtained  US FDA clearance for the SafeOp automated neuromonitoring system for use in real-time intraoperative nerve location and assessment. The system relies on somatosensory evoked potential (SSEP) and and electromyography (EMG) as the two complementary modalities, one for evaluating the functionality of nerves and the other their locati...
Source: AstraZeneca  Mar 03, 2019  3 years ago
AstraZeneca and MSD have announced positive results from the Phase III POLO trial, in which there was a statistically significant and clinically meaningful improvement in progression-free survival (PFS) with Lynparza (olaparib) for pancreatic cancer, making it the first PARP inhibitor to demonstrate benefit in the disease. The drug is a first-in-class PARP inhibitor, and the first targeted treat...
Source: Tufts University  Mar 03, 2019  3 years ago
The World Cancer Research Fund reports that 30 to 50 percent of cancer cases are preventable, and it is important to focus on stopping cancer from developing in the first place. Many natural foods contain a variety of antioxidants and phytochemicals that possess the capability of preventing cancer from developing coupled with a proper lifestyle. Xiang-Dong Wang, a senior scientist and associate...
Source: University of Alabama at Birmingham  Mar 02, 2019  3 years ago
In a paper recently published in the Journal of Infectious Diseases, researchers examined the effect of vaginal tenofovir 1 percent gel use on the risk of acquiring herpes simplex virus type 2, or HSV-2. The study was conducted through a secondary analysis of data from the VOICE study. According to the Centers for Disease Control and Prevention, more than one in six Americans ages 14 to 49 ...
Source: University of Pittsburgh  Mar 01, 2019  3 years ago
A single misbehaving protein -- called TDP-43 -- is behind 97 percent of amyotrophic lateral sclerosis (ALS) cases and 45 percent of frontotemporal dementia diagnoses. It also is found in 80 percent of chronic traumatic encephalopathy and 60 percent of Alzheimer's disease cases. Now, University of Pittsburgh researchers have found a way to trap TDP-43 so it doesn't form toxic clumps that c...
Source: University of Michigan  Feb 28, 2019  3 years ago
A protein molecule called EZH2,  known to play a role in cancer may also be increasing fibrosis in scleroderma patients.   Studies and researches that have been made show that Scleroderma, a rare chronic autoimmune disease, causes difficulties during breathing, exhaustion and most concerningly hardens the internal organs and the skin. “Tissues and organs are damaged due to...
Source: Children's Hospital of Philadelphia  Feb 27, 2019  3 years ago
New preclinical findings from extensive cell and animal studies suggest that a drug already used for a rare kidney disease could benefit patients with some mitochondrial disorders -- complex conditions with severe energy deficiency for which no proven effective treatments exist. Future clinical research is needed to explore whether the drug, cysteamine bitartrate, will meaningfully benefit patient...
Source: Indiana University, US  Feb 26, 2019  3 years ago
A breakthrough test developed by Indiana University School of Medicine researchers to measure pain in patients could help stem the tide of the opioid crisis in Indiana, and throughout the rest of the nation. A study led by psychiatry professor Alexander Niculescu, MD, PhD and published this week in the Nature journal Molecular Psychiatrytracked hundreds of participants at the Richard L. Ro...
Source: University of Virginia Health System  Feb 25, 2019  3 years ago
Researchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease. The discovery points to a potential new treatment for the autoimmune disorder and may also allow the use of a simple blood test to detect people at elevated risk for developing the condition. The pr...
Source: Vanderbilt University  Feb 24, 2019  3 years ago
A well-known, four-year study found popular arthritis drug Celebrex no more dangerous for the heart than older drugs in its same classification - commonly called NSAIDs. Now, a big-data analysis of patient records at Vanderbilt University has found a link specifically between Celebrex and heart valve calcification. W. David Merryman, professor of biomedical engineering, and Ph.D. student Megan B...
Source: Rutgers University  Feb 24, 2019  3 years ago
A Rutgers study has found that a specific gene in cancerous prostate tumors indicates when patients are at high-risk for the cancer to spread, suggesting that targeting this gene can help patients live longer. The study, which was published in the journal Nature Communications, identified the NSD2 gene through a computer algorithm developed to determine which cancergenes that spread in a&nb...
Source: Vanderbilt University  Feb 23, 2019  3 years ago
Verticilide, an extract from the genus of fungus Verticillium, commonly found on plants and insects, is a promising compound to treat arrhythmia according to a research from a collaboration between Vanderbilt University professors of chemistry and medicine. Jeffrey Johnston, Stevenson Professor of Chemistry, said the natural product isn't active except in insects, but the synthetic mirror-i...
Thailand Medical News  Feb 22, 2019  3 years ago
We continue our series of stock recommendations, still focusing on Medical and Biotech stocks in the US, as considering the political uncertainties facing Thailand, its best to stay clear of the Thailand Stock Market for the rest of the year. Medical and Biotechnology  stocks are  simultaneously one of the most exciting and one of the riskiest corners of the stock market. Biotech co...
Source: University of California - Riverside  Feb 22, 2019  3 years ago
Multiple sclerosis is an autoimmune disease that affects more than 2.3 million people worldwide. This debilitating condition periodically shutters communication between the brain and other parts of the body, resulting in symptoms that range from numbness and tingling in the arms and legs to blindness and paralysis. While treatments are available to alleviate inflammation, no therapies exist to pro...
Source: Thailand Medical News  Feb 21, 2019  3 years ago
Doctors In Thailand practicing primary care medicine in 2019 have likely met this familiar greeting from a patient: “I Googled my symptoms and I think the problem is [insert condition].” Obviously, this can be unsettling for many providers – doctors in the past were often the first point of reference for patients who otherwise had no way of researching their health concerns on th...
Source: San Diego School Of Medicine  Feb 20, 2019  3 years ago
Proton pump inhibitors (PPIs), which include well-known brand names Prilosec, Miracid, Nexium and Prevacid, are among the most commonly prescribed medications in the world. Approximately 10 percent of adults in the United States take these drugs for frequent heartburn, acid reflux and gastroesophageal reflux disease. Given their prevalence, researchers at Skaggs School of Pharmacy and Pharmaceutic...
Source: University Of Melbourne  Feb 19, 2019  3 years ago
Scientists from the University Of Melbourne said  on Monday that they had discovered immune cells that can fight all known flu viruses in what was hailed as an "extraordinary breakthrough" that could lead to a universal, one-shot vaccine against the killer disease. Influenza epidemics, largely seasonal, kill hundreds of thousands of people each year, according to the World Health ...
Thailand Medical News  Feb 18, 2019  3 years ago
Osteoarthritis  is the most common of the more than 200 forms of arthritis, affecting over 20 per cent of the population. Unfortunately, there are currently no effective treatments or approved drugs for this disabling condition, which causes the joints to become painful and stiff. Some new drugs are in the pipeline, but it will be years before they are tested in clinical trials and ...
Source: Dana-Farber Cancer Institute  Feb 18, 2019  3 years ago
A combination of two drugs -- one of them an immunotherapy agent -- could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial. Patients who received the immunotherapy drug avelumab plus axitinib, a targeted agent, had a significant advantage in progression-...
Source: Albumedix Ltd  Feb 17, 2019  3 years ago
Overcoming Formulation Challenges of Biotherapeutics: The increasing study of vaccines and biotherapeutics gives promise for improvement of treatments against various diseases. While protein engineering has shown a great level of growth, several of these therapies persist in the face of ex vivo uncertainty challenges (both physical and chemical instability) which are a source of dosage form inadeq...
Source: Thailand Medical News  Feb 17, 2019  3 years ago
Multiple therapies involving ablative and nonablative techniques have been developed for rejuvenation of photodamaged skin. Monopolar radiofrequency (RF) is emerging as a gentler, nonablative skin-tightening device that delivers uniform heat to the dermis at a controlled depth.   In a recent study done by Dr Moetaz El-Domyati, Head of Dermatologists at Minia University, Egypt in collaborati...
Source: Thailand Medical News  Feb 17, 2019  3 years ago
Updated treatment guidelines and the availability of the ResistancePlus GC test for Neisseria gonorrhoeae, from SpeeDx Inc, Sydney, Australia, are making it possible for some UK patients with gonorrhea to be treated with the cheap and easily-administered oral antibiotic ciprofloxacin.    Ciprofloxacin was the first-line antibiotic of choice for uncomplicated gonorrhea in the ...
Source: St Thomas' Biomedical Research Centre  Feb 17, 2019  3 years ago
A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months.   Researchers at the NIHR Guy's and St Thomas' Biomedical Research Centre (BRC) developed the technique by studying white blood cells taken from patien...
Source: NRG Oncology, Pennsylvania  Feb 17, 2019  3 years ago
The NRG Oncology clinical study NRG-RTOG 0415 determined that a hypofractionated radiotherapy schedule (H-RT), a treatment schedule that delivers a total dose of radiotherapy over a shorter period of time, is not worse than the conventional radiotherapy schedule (C-RT) in terms of bowel, bladder, sexual, and general quality of life (QOL) as well as anxiety and depression for men with low risk pros...
Thailand Medical News  Feb 16, 2019  3 years ago
Twelve patients who tried injections of stem cells were hospitalized with infections, according to a report in the New York Times that should cause patients concern. More important is that they should investigate stem cell treatments, for conditions such as cartilage injuries to their joints, before committing to one of these procedures. It's also a valuable reminder that physic...
Source: Oregon Health and Science University  Feb 16, 2019  3 years ago
A team of researchers from Oregon Health and Science University has concluded from an extensive study involving a medicinal plant called Centella Asiatica, commonly known as Gotu Kola (in thai: bua bok ) is effective in terms of improving memory especially in the elderly and those afflicted with cognitive related diseases. Centella Asiatica  contains a variety of phyto chemicals such ...
Source: University of Exeter  Feb 16, 2019  3 years ago
Scientists have discovered new ways in which the body regulates blood clots, in a discovery which could one day lead to the development of better treatments that could help prevent and treat conditions including heart diseases, stroke and vascular dementia.   Led by the University of Exeter and funded by the British Heart Foundation, the team has developed a new technique  that allows ...
Takeda Pharmaceutical Company   Feb 15, 2019  3 years ago
– ADCETRIS in Combination with AVD (Adriamycin, Vinblastine and Dacarbazine) Demonstrated 29-Percent Reduction in the Risk of Progression, Death or Need for Additional Anticancer Therapy for CD30+ Stage IV Patients   – Milestone Marks Fifth Approved Indication for ADCETRIS in Europe, Reinforcing Takeda’s Commitment to Developing Innovative Solutions for People Li...
Source: George Mason University   Feb 15, 2019  3 years ago
George Mason University's Yuntao Wu is the lead scientist on a research team that has identified a measurable indicator that could prove instrumental in the fight against HIV. The research focuses on cofilin, a key protein that regulates cells to mobilize and fight against infection. In an HIV-infected patient, cofilin dysfunction is a key factor in helper T cell defects, according to the r...
Source: ETH Zurich University  Feb 15, 2019  3 years ago
In recent years, the number of targeted cancer drugs has continued to rise. However, conventional chemotherapeutic agents still play an important role in cancer treatment. These include platinum-based cytotoxic agents that attack and kill cancer cells. But these agents also damage healthy tissue and cause severe side effects. Researchers at ETH Zurich have now identified an approach that allows fo...
Source: University Hospital Basel   Feb 15, 2019  3 years ago
There is a higher risk of fragility bone fracture for people with diabetes, and a new study was able to identify a key factor specific to type 1 diabetes (T1D) patients.   The study in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism reports that poor glucose control significantly reduces the risk, in T1D patients, of a fall from standing height or...
Source: University of Virginia  Feb 15, 2019  3 years ago
An antidepressant drug used to treat obsessive-compulsive disorder could save people from deadly sepsis, new research from the University of Virginia School of Medicine suggests. Sepsis is a significant cause of death around the world. The federal Centers for Disease Control and Infection calls it "the body's extreme response to an infection." Essentially, the body's immune re...
Thailand Medical News  Feb 14, 2019  3 years ago
A variety of health care trackers, including the Apple Watch, offer consumers the ability to record their ECG signals. Though the claims about these offerings are mostly accurate, they may be misleading to those that believe these devices mimic the capabilities of in-hospital ECGs. In reality, wrist-worn and other wearable ECG monitors are only single-lead devices that can pretty much only detect ...
Thailand Medical News  Feb 14, 2019  3 years ago
As in much of the rest of the developed and middle-income nations, diabetes is creating a public health crisis in Thailand. Doctors face a complicated set of challenges related to the illness – not only in how to treat those already affected, but how to prevent the debilitating disease moving into the future. Measures such as proper dietary education and the promotion of exercise, especially...
Source: University of Leicester  Feb 14, 2019  3 years ago
Results from a phase II clinical trial, experimental work on cells and computational modelling have together shown why the first pill for asthma in 20 years can help reduce asthma attacks. Researchers from Leicester (UK) and Vancouver (Canada) have shown that the investigational drug, Fevipiprant (an oral, selective prostaglandin D2 receptor antagonist), reduces the amount of smooth muscle in t...
Source: University of Cambridge/ University of Leicester  Feb 13, 2019  3 years ago
A blood test has been developed that could save countless lives by improving early detection of lung cancer. The test measures circulating DNA that is shed by cancer cells as they grow and multiply. Scientists believe it could predict the presence of low-grade tumours in the lungs long before they become a threat.   New research led by scientists at the Medical Research Council (MRC) Toxico...
Source: Stanford University School of Medicine  Feb 12, 2019  3 years ago
An antibody-based treatment can gently and effectively eliminate diseased blood-forming stem cells in the bone marrow to prepare for the transplantation of healthy stem cells, according to a study in mice by researchers at the Stanford University School of Medicine. The researchers believe the treatment could circumvent the need to use harsh, potentially life-threatening chemotherapy or radiati...
Source: Beth Israel Deaconess Medical Center  Feb 11, 2019  3 years ago
Lightheadedness with standing, otherwise known as postural lightheadedness, results from a gravitational drop in blood pressure and is common among adults. While mild in many adults, it has been cited as an important contributing factor in some harmful clinical events, such as falls. As a result, greater sodium intake is widely viewed as an intervention for preventing lightheadedness when moving f...
Source: The Institute of Cancer Research, London  Feb 10, 2019  3 years ago
A brand new type of cancer drug that acts as a ‘Trojan horse’ to get inside tumour cells has shown promise in patients with six different cancer types. In patients with advanced, drug-resistant cancers, over a quarter with cervical and bladder tumours, and nearly 15 per cent with ovarian and lung tumours, responded to the new treatment. The innovative new drug, called tisotumab ved...
Source: Duke University Medical Center  Feb 09, 2019  3 years ago
The use of MRI to determine heart function has been slow to catch on, but a study from Duke Health researchers shows that stress cardiac MRI not only diagnoses disease, but can also predict which cases are potentially fatal. Results from a large, multi-center study suggest that cardiac magnetic resonance, or CMR, has potential as a non-invasive, non-toxic alternative to stress echocardiograms, ...
Source: Massachusetts Institute of Technology  Feb 08, 2019  3 years ago
An MIT-led research team has developed a drug capsule that could be used to deliver oral doses of insulin, potentially replacing the injections that people with type 2 diabetes have to give themselves every day. An MIT-led research team has developed a drug capsule that could be used to deliver oral doses of insulin. Credit: Felice Frankel About the size of a blueberry, the capsule contains a...
Source: Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem (INBEB), Brazil  Feb 07, 2019  3 years ago
Scientists explored mRNA and protein public databases to unravel hidden meanings of the genetic code. Using a metric derived from mRNA codon composition, they found out how gene sequence choice can predict different aspects of protein synthesis, such as protein production efficiency. The study could help the development of new biotechnological applications of genes and proteins. Today, thousand...
Thailand Medical News  Feb 07, 2019  3 years ago
Thailand’s PrEP Implementation Progress With Exclusive Interview Comments From Professor Andrew Grulich – The Kirby Institute, UNSW, Sydney PrEP implementation was a very hot, challenging topic at the 21st Bangkok International Symposium on HIV Medicine 2019 organised by HIV-NAT. The Symposium was held at The Queen Sirikit National Convention Centre, January 16-18th.. The latter par...

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