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Gastroenterology
Discover all the latest developments and discoveries about various digestive disorders and diseases including those associated with the liver, pancreas and bile ducts etc.
Source: Pterostilbene  Sep 24, 2020  2 months ago
Pterostilbene (PSB) a polyphenolic phytochemical that occurs in plants, particularly small berries and nuts has been identified by Japanese researchers from the Tokyo University of Science as a new therapeutic option for chronic inflammatory disorders. The study findings are published in the FASEB Journal: (Journal of the Federation of American Societies for Experimental Biology) https://faseb.on...
Source: COVID-19 Gut  Sep 08, 2020  3 months ago
COVID-19-Gut: A new study by researchers from the Chinese University of Hong Kong has found that the SARS-CoV-2 coronavirus may continue to infect and replicate in the digestive tract after clearing in the airways. https://www.cpr.cuhk.edu.hk/en/press_detail.php?id=3356   It was also observed that COVID-19 patients have active and prolonged gut viral infection, even in the absence of gastro...
Source: Proton Pump Inhibitors or PPIs  Sep 06, 2020  3 months ago
Proton pump inhibitors or PPIs which already have a bad reputation due to various numerous medical and health complications associated with it now has another new complication associated with its use ie risk of developing fatty liver disease   https://www.thailandmedical.news/news/ppis-or-acid-reflux-drugs-affects-cognitive-abilities-of-breast-cancer-survivors   https://www.thailandmed...
Source: COVID-19 And Fatty Liver Disease  Sep 04, 2020  3 months ago
COVID-19 And Fatty Liver Disease: Researchers from the University of Minnesota and John Hopkins School of Medicine in a new observational study reveal that individuals with non-alcoholic fatty liver disease and steatohepatitis have increased odds of hospitalization due to coronavirus disease (COVID-19); conversely, metabolic surgery was found to be protective against the admission of inf...
Source: Oxytocin and Gastroenterology  Sep 01, 2020  3 months ago
Oxytocin which is also known as the love hormone, plays an important role in stress' disruption of digestion such as bloating, discomfort, nausea, and diarrhea according to a new study by researchers from Penn State University- College of Medicine that was sponsored by a grant from the U.S. National Institute of Health.   The study findings are published in The Journal of Physiology. ht...
Source: Fructose Sweeteners  Aug 25, 2020  3 months ago
Fructose Sweeteners: Contrary to previous fallacies, researchers from the University of California-San Diego School of Medicine report that fructose adversely affects the liver only after it reaches the intestines, where the sugar disrupts the epithelial barrier protecting internal organs from bacterial toxins in the gut. The researchers say that developing treatments that prevent intestinal barri...
Source: Antibiotics and Microbiome  Jul 02, 2020  5 months ago
Antibiotics: Researchers from the University Of Melbourne and Baylor College of Medicine-Texas have found in a new study that antibiotic exposure during crucial developmental periods in early childhood alters digestive tract nerve function and bacterial colonies.   The research finds are published in the American Journal of Physiology-Gastrointestinal and Liver Physiology. https://jour...
Source: Gut Microbiota  Jun 26, 2020  5 months ago
Gut Microbiota: According to research led by a University of Massachusetts Amherst food scientist, a common food additive called E171 which recently banned in France but allowed in the U.S. and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver.   The study findings were published in...
Source: Gut Microbiome  Jun 11, 2020  6 months ago
Gut Microbiome: Medical researchers at Princeton University have developed a systematic approach for evaluating how the microbial community in the human intestines can chemically transform, or metabolize, oral medications in ways that impact their safety and efficacy.   The study is published in the journal: Cell. https://www.sciencedirect.com/science/article/pii/S0092867420305638...
Source: Gut Microbiome  Jun 10, 2020  6 months ago
Gut Microbiome: According to a new study by researchers from Augusta University-Georgia, females especially those with untreated hypertension would benefit by reducing salt intake to what is considered a healthier level as it will help maintain a healthy  gut microbiome and also normalize their  blood pressure.   The study was published in the AHA’s journal: Hypertension. ht...
Source: Probiotics  Jun 09, 2020  6 months ago
Probiotics: After a careful review and analysis of all available research publications and reports, the American Gastroenterological Association (AGA) has released new clinical guidelines that state for most digestive conditions there is not enough evidence to support the use of probiotics.   The AGA publication is the first clinical guideline to focus on probiotics across multiple GI disea...
Source: Gastroenterology News  May 05, 2020  7 months ago
Gastroenterology: Medical researchers have developed a new treatment protocol involving a three-drug combination of omeprazole, amoxicillin, and rifabutin in one capsule called RHB-105 that effectively eradicates Helicobacter pylori infection in adults. The novel formulation was found to still be effective and well-tolerated in an environment of clinically significant antibiotic resistance. &nbs...
Source: Thailand Medical News  Feb 12, 2020  10 months ago
Each year globally, almost a million people are diagnosed with C. difficile infections and more than 140,000 die, according to the Centers for Disease Control and Prevention. It was also observed that taking antibiotics increases a person's risk of infection.   Clostridioides difficile infection (CDI or C-diff), also known as Clostridium difficile infection...
Source: Thailand Medical News  Feb 07, 2020  10 months ago
Research led by Texas A&M AgriLife Research scientists reveal a natural compound found in many well-known and widely consumed vegetables can also be used to fight fatty liver disease. The new study demonstrates how non-alcoholic fatty liver disease, or NAFLD, can be controlled by indole, a natural compound found in gut bacteria and in cruciferous vegetables such as cabbage, kale, cauliflower a...
Source: Thailand Medical News  Jan 28, 2020  10 months ago
For many years, a widespread, fast-growing algae plant called Chlamydomonas reinhardtii  the green, single-celled organism, which primarily grows in wet soil, has served as a model species for research topics spanning from algae-based biofuels to plant evolution. While other species of algae have been used as dietary nutraceuticals that provide beneficial oils, vitamins, proteins, c...
Source: Thailand Medical News  Dec 11, 2019  12 months ago
Canadian researchers in a new study suggests that specialized immune cells that dampen inflammation and help repair the gut could be used as a potential therapy for children dealing with the painful symptoms of inflammatory bowel disease (IBD). A study by the BC Children's Hospital and the University of British Columbia shows that a specific type of T cell, called a Tr1 cell, produces a che...
Source: Thailand Medical News  Dec 09, 2019  12 months ago
Approximately 26 million people globally  have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 470,000 new cases are diagnosed each year. IBD patients suffer from pain, extreme discomfort, and many other symptoms caused by continuously relapsing and remitting inflammatory lesions in the layer of cells that lines the intestinal ...
Source: Thailand Medical News   Nov 30, 2019  1 year ago
Medical researchers from the University of Helsinki have developed a new diagnostic method for the rapid on-site measurement of antibodies from patient samples. They have applied this new method for the diagnostics of celiac disease, with promising results.   Point-of-care (POC) testing is a rapidly growing sector, bringing medical testing from central laboratories to where the patient is rec...
Source: Thailand Medical News  Nov 24, 2019  1 year ago
A new study out of the University of Alberta suggests short-term increases in sugar consumption could increase the risk of inflammatory bowel disease and have a significant impact on our health. The study published in Scientific Reports, mentioned that the researchers found that mice had an increased susceptibility to chemically induced colitis and more severe symptoms after only two days ...
Source: Thailand Medical News  Oct 22, 2019  1 year ago
A new treatment protocol for Celiac Disease was unveiled at the European Gastroenterology Week conference in Barcelona, Spain. The Northwestern University Feinberg School of Medicine showcased results of a new phase 2 clinical trial using technology developed that show it is possible to induce immune tolerance to gluten in individuals with celiac disease. The findings may pave the way for tre...
Source: Thailand Medical News  Oct 05, 2019  1 year ago
A lot of individuals often experience symptoms associated with abdominal bloating and although 30% of the time is just a minor occurrence that goes away but on the other hand it could also signal something more serious or an underlying medical condition. Abdominal  is a feeling of fullness and tightness in the abdomen (tummy). It is a common problem affecting 30-70% of individuals sometime or...
Source: Thailand Medical News  Sep 27, 2019  1 year ago
Thailand Gastroenterology A large cohort study conducted jointly by medical researchers from Sungkyunkwan University School of Medicine in Korea and Johns Hopkins Medical Institution in Maryland, USA have indicated that the use of proton pump inhibitors (PPIs) contributes to increased risk of cholangitis.   Cholangitis is an inflammation of the bile duct system. The bile duct system ca...
Source: Thailand Medical News  Aug 12, 2019  1 year ago
There is currently no cure for the more than 62 million people in the world  living with Crohn's disease (CD) and its symptoms, including abdominal pain, intestinal distress and severe weight-loss. CD is a form of inflammatory bowel disease (IBD) in which the body's own immune system attacks the gastrointestinal tract, and treatment is focused on controlling the symptoms of the diseas...
Source: Thailand Medical News  Jun 28, 2019  1 year ago
Researchers from John Hopkins Bloomberg School of Public Health have discovered that the incidence of gastrointestinal bloating was higher in individuals that consumed diets high in salt. Based on analysis of data from the largest clinical trial called DASH-Sodium (Dietary Approaches to Stop Hypertension-Sodium), the team from John Hopkins found that that high sodium intakes increased bloating ...
Source: Thailand Medcial News  May 24, 2019  2 years ago
Fatty liver disease is a prevailing disease affecting around 17% of the global population  and  actually comprises of a variety of specific liver conditions that caused due to existing diabetic or obesity conditions. Very often individuals affected are not even aware in the initial stages till symptoms manifest itself in the later stages of the disease.   Its occurrence is more pr...
Source: Case Western Reserve University   Apr 04, 2019  2 years ago
Probiotics typically aim to rebalance bacteria populations in the gut, but new research suggests they may also help break apart stubborn biofilms. Biofilms are living microbial communities—they provide a haven for microbes and are often resistant to antibiotics. A new study describes a specific probiotic mix that could help patients with gastrointestinal diseases avoid harmful biofilms that ...
Source: Brigham and Women's Hospital  Apr 02, 2019  2 years ago
Food allergies, celiac disease, inflammatory bowel disease (IBD), diarrhea and other gastrointestinal diseases have something in common: all have been linked to epithelial barrier loss. The gut epithelial barrier—that critical lining of cells in the gut that must allow nutrients into the body while keeping food-borne microbes out—can be compromised during intestinal inflammation and ca...
Source: Mayo Clinic  Mar 23, 2019  2 years ago
Drug therapy may effectively treat a potentially life-threatening condition associated with cirrhosis and other chronic liver diseases, according to a new study by Mayo Clinic researchers.  While therapies have been available to treat some forms of liver disease, including hepatitis C and autoimmune hepatitis, options have been more limited for treating portal hypertension, a conditio...
Source: University of Southern California  Mar 06, 2019  2 years ago
USC researchers provided evidence that a low-calorie "fasting-mimicking" diet has the potential to reduce inflammation and repair the gut. Published in a recent  edition of Cell Reports, the study reports on the health benefits of periodic cycles of the diet for people with inflammation and indicated that the diet reversed inflammatory bowel disease (IBD) patholo...
Source: St Thomas' Biomedical Research Centre  Feb 17, 2019  2 years ago
A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months.   Researchers at the NIHR Guy's and St Thomas' Biomedical Research Centre (BRC) developed the technique by studying white blood cells taken from patien...
Source: Friedrich-Alexander Universitat(FAU),Germany  Feb 05, 2019  2 years ago
More than 4000,000 people in Germany are affected by the chronic inflammatory bowel diseases Morbus Crohn or ulcerative colitis. Patients often suffer from flare-ups, which damage intestinal tissue. In spite of tremendous advances in treating the diseases with medication, the chronic inflammation still cannot be kept sufficiently in check for a number of patients. Until now, little has been known ...
Source: University Of Melbourne  Jan 22, 2019  2 years ago
Researchers studying lupus discovered that treatments similar to those already in use to treat melanoma and lung cancer, including immunotherapy, show promise for stomach cancer and may even lead to preventative treatments. Usually the symptoms of stomach or gastric cancer are hard to pick up until it’s too late, making what is a relatively common cancer an often fatal one. Survival rate...
Source: University of Louisville  Jan 10, 2019  2 years ago
Scientists at the University of Louisville have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, can reduce and protect against inflammatory bowel disease (IBD). Millions of people worldwide suffer from IBD in the form of either ulcerative colitis or Crohn's disease, and few effective long-term treatments are available. Illustration s...
Source: University of Groningen  Jan 01, 2019  2 years ago
A team of researchers with members from the Netherlands and the U.S. has found differences in the numbers of gut microbes for patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). In their paper published in the journal Science Translational Medicine the group describes how they sequenced the genome of gut microbes in patients with bowel problems and what they found. ...
Source: VIB (the Flanders Institute for Biotechnology)  Nov 25, 2018  2 years ago
Scientists from the VIB-UGent Center for Inflammation Research identified the mechanisms by which the bacterial pathogen Clostridium difficile kills intestinal epithelial cells (IECs), thus destroying the protective mucosal barrier of the intestinal tract. The researchers demonstrate the physiological relevance of this process during infection and have published their findings in Nature Commu...
Source: Walter and Eliza Hall Institute  Nov 06, 2018  2 years ago
Australian researchers have uncovered clues in the immune system that reveal how the balance of 'good' gut bacteria is maintained. This information could help in the prevention and treatment of inflammatory bowel disease (IBD). The study, published in the journal Nature Communications, showed that the increased presence of a protein responsible for sensing infection -- called NLRP1 --...
Source: University Of North Carolina  Oct 26, 2018  2 years ago
Internists now know that patients who have a sibling with diverticulitis can have three times the risk for the disease, and a low-risk lifestyle decreases risk of incident diverticulitis by half. Nuts, seeds, and popcorn are now OK. Annually in the U.S., diverticulitis is responsible for 2.5 million office visits, 333,000 ED visits, 216,000 hospital admissions, and health care costs of $3.5 bill...
Source: University of Miami Miller School of Medicine  Aug 28, 2018  2 years ago
With only two treatment options for primary biliary cholangitis, some hepatologists have cast a new eye on an older class of drugs. Fibrates, used for the treatment of dyslipidemia in the United States since the 1970s, had been shown to decrease levels of alkaline phosphatase (ALP), said Cynthia Levy, MD, FAASLD, an associate professor of medicine at the University of Miami Miller School of Medic...
Source: The Journal of Physiology  Aug 08, 2018  2 years ago
Eating high fibre foods may reduce the effects of stress on our gut and behaviour, according to new research published in The Journal of Physiology.   Stress is a significant health concern and can cause major changes in the gut and in the brain, which can cause changes in behaviour. In recent years there has been growing interest in the link between gut bacteria and stres...
Source: Multiple  Jul 23, 2018  2 years ago
Scientists examined whether diet may be affecting the success of Helicobacter pylori treatment, and looked at whether nutrients such as cholesterol and omega-3 fatty acids play a role.   Helicobacter pylori is a global health issue responsible for gastritis and gastric ulcers. Approximately 50% of the global population suffers from Helicobacter pylori infection, which...
Source: Beth Israel Deaconess Medical Center  Jul 22, 2018  2 years ago
Nearly 30 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Since then, antibiotics have become the primary therapy used to combat the H. pylori infection, which affects approximately six percent of the world population and is also a primary cause of stomach cancer. But today the bacteria is growing increasingly resista...
Source: Massachusetts General Hospital  Jul 21, 2018  2 years ago
This week, meat-eaters receive another diet-based kick in the ribs. A new study, published in the journal Gut, links the consumption of red meat to an increased risk of developing diverticulitis.  A recent study uncovers a link between the consumption of red meat and diverticulitis. Diverticulitis is a relatively common complaint that occurs when bulging sacs appear in the lining...
Source: Technischen Universität München   Jul 20, 2018  2 years ago
The exact cause of irritable bowel syndrome has been unknown. However, scientists have identified an organic cause of irritable bowel syndromes, reveals a new study.       An international team with significant involvement from the Technical University of Munich (TUM) has provided initial clues about the organic triggers of the disease, which affects an estimated one out of six peop...

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