Pharmaceuticals: The US Food and Drug Administration has approved nivolumab (OPDIVO) by Bristol-Myers Squibb for patients with unresectable advanced, recurrent or metastatic esophageal squamous cell carcinoma (ESCC) after prior fluoropyrimidine- and platinum-based chemotherapy.
Proof for efficacy was investigated in ATTRACTION-3 (NCT02569242), a multicenter, randomized (1:1), active-controlled,...
Source: India Medical News Jun 12, 2020 3 years ago
India Medical News: The COVID-19 crisis is fast spiraling out of control in India. As of Friday (12th June), the total number of COVID-19 infected cases has reached 298,291 while the total number dead from the coronavirus have reached 8,501. The total deemed to have recovered according to health authorities are 147,195 while about 11,134 are in critical care. On Thursday alone, a record of almost ...
Source: Diabetic Retinopathy Jun 12, 2020 3 years ago
Diabetic retinopathy is a typical complication of diabetes and a leading cause of blindness in the world. A new research by scientist from University Of Oklahoma show that visual function in diabetic mice was significantly improved after treatment with a single dose of visual chromophore 9-cis-retinal, a vitamin A analog that can form a visual pigment in the retina cells, thereby producing a light...
Brain Damage: Researchers in a collaborative study involving the NeuroGrow Brain Fitness Center in Virginia, John Hopkins, Washington University and University Of California have published a research paper with a comprehensive review of the COVID-19's effect on the nervous system which classifies brain damage caused by COVID-19 into three stages.
The research is published in The ...
Source: Interferon Lambda Jun 12, 2020 3 years ago
Interferon Lambda: Medical researchers from the Francis Crick Institute in England have found that a protein called Interferon Lamba which has antiviral properties and is initially helpful in the body's immune response to viruses, can later interfere with the repair of damaged lung tissue by inhibiting the repair process.
The researchers led by Dr Andreas Wack from the Institute...
COVID-19 WARNING: A new study by Northwestern University indicates that the SARS-CoV-coronavirus literally threatens the whole nervous system.
The study indicates that the SARS-CoV-2 coronavirus disease also involves multiple other organs, not just the respiratory tract, including the central and peripheral nervous system.
Disturbingly, the number of recognized neurologic manifesta...
Source: COVID-19 Antibody Test Jun 12, 2020 3 years ago
COVID-19 Antibody Test: Scientists and researchers from University Of North Carolina School Of Medicine have developed a new kind of antibody test that could be ramped up to test thousands of blood samples at labs that do not have the resources of commercial labs and large academic medical centers.
The team created a blood test to pinpoint SARS-CoV-2 antibodies that target one u...
US MEDICAL NEWS: The American Thoracic Society has published a study paper that warns about the impending drug shortage that the United States will face if not already facing.
The research paper is published in the Annals of the American Thoracic Society and examines the nation’s current shortage of vitally needed medications, and how this dangerous situation is being made...
Source: Acute Pancreatitis Jun 11, 2020 3 years ago
Acute Pancreatitis: A disturbing revelation has been made by a new study conducted by researchers from the University Of Liverpool. The study shows that acute pancreatitis is now materializing in certain COVID-19 patients and also provides a guideline to identifying the condition.
The research findings were published in Gastroenterology, identifies the signs of COVID-19 related pancr...
BCG Vaccine: Initially several researchers and prominent news outlets have noticed that countries still administering the Bacillus Calmette-Guérin vaccine against tuberculosis had fewer coronavirus cases and fewer deaths per capita in the outbreak’s early stages. This led many to assume that the BCG vaccine could to a certain degree protect against the COVID-19.
However mor...
Source: Hydroxychloroquine Jun 11, 2020 3 years ago
Hydroxychloroquine: Researchers in a new study from Netherlands in collaboration with scientists from US and Germany show that the drug hydroxychloroquine suppresses a form of immunity called ‘trained immunity,’ with repercussions for its potential use to treat COVID-19.
Hydroxychloroquine is an anti-malarial and a disease-modifying anti-rheumatic drug (DMARD), whi...
Source: COVID-19 Diagnostics Jun 11, 2020 3 years ago
COVID-19 Diagnostics: As the SARS-CoV-2 has the potential to mutate, and numerous studies and genomic sequencings have already shown that many mutated strains of the SARS-CoV-2 has emerged, it is critically significant to check the efficacy of current diagnostic tests, warns York University researchers, who found seven out of 27 methods had potential sequence mismatch issues that may lead to under...
Gut Microbiome: Medical researchers at Princeton University have developed a systematic approach for evaluating how the microbial community in the human intestines can chemically transform, or metabolize, oral medications in ways that impact their safety and efficacy.
The study is published in the journal: Cell. https://www.sciencedirect.com/science/article/pii/S0092867420305638...
US Medical News: The state of Texas on Wednesday (June 10) reported 2,504 new COVID-19 cases, the highest one-day total since the pandemic emerged.
Also, a month into its reopening, Florida this week reported 8,553 new cases - the most of any seven-day period.
Meanwhile California's hospitalizations are at their highest since May 13 and have risen in nine of the past 10 days.
&...
According to new report published in the British Medical Journal (BMJ), the food industry shares the blame not only for the obesity pandemic but also for the severity of COVID-19 disease and its devastating consequences. https://www.bmj.com/content/369/bmj.m2237
Medical researchers at Queen Mary University of London say coronavirus has made tackling the obesity pandemic even more urgent, an...
Source: Neutrophils And COVID-19 Jun 11, 2020 3 years ago
Neutrophils or a type of white blood cell may be central to the immune system overreaction that is the most common cause of death for COVID-19 patient. Now researchers from the University of Michigan have that found that rod-shaped particles can take them out of circulation and hence prevent the deadly immune responses.
The research findings are published in the medical journal: Science A...
Source: Singapore and Facebook Jun 11, 2020 3 years ago
Facebook has labeled on its platform a research by credible Singaporean doctors from the prestigious Singapore Government owned hospital : The Singapore General Hospital as false. The research which focuses about the usage of the vitamin and mineral combination of Vitamin D, Vitamin B12 and Magnesium to help prevent elderly patients from progressing into severe stages of the COVID-19 d...
Source: Indonesia Medical News Jun 10, 2020 3 years ago
Indonesia Medical News: The South-East Asian country with the biggest population: Indonesia posted a record number of SARS-CoV-2 coronavirus infections on Wednesday, sparking calls from health experts for the world's fourth most populous country to slam the brakes on easing restrictions.
The week before, Jakarta the capital opened mosques for the first time in nearly three months, as ...
Source: COVID-19 Research Jun 10, 2020 3 years ago
COVID-19 Research: A new French research has revealed that the hypothalamus region of the brain is a target area for the SARS-CoV-2 coronavirus as the researchers have also discovered that the region is rich with ACE-2 receptors and also TMPRSS2 receptors and that the SARS-CoV-2 brain invasion is through multiple routes, along the fact that sex hormones and metabolic diseases influence brain susce...
Source: COVID-19 and Mixed Reality Jun 10, 2020 3 years ago
Mixed Reality (MR): An innovative project at the Imperial College Healthcare NHS Trust has brought the versatility of mixed and augmented reality products to the forefront of the news. Called the Imperial led project, the initiative has doctors wearing the Microsoft Hololens headsets whilst working on the front lines of the COVID pandemic, to aid them in their care for their patients. ht...
Gut Microbiome: According to a new study by researchers from Augusta University-Georgia, females especially those with untreated hypertension would benefit by reducing salt intake to what is considered a healthier level as it will help maintain a healthy gut microbiome and also normalize their blood pressure.
The study was published in the AHA’s journal: Hypertension.
ht...
Source: COVID-19, Influenza and Next Wave Jun 10, 2020 3 years ago
Scientists initially attempted to use meteorological factors to explain the spread of the SARS-CoV-2 coronavirus in mainly cold climates, which were experiencing winter. However, factors like temperature, relative humidity, and exposure to natural ultraviolet radiation from sunlight, do not explain the variation in disease incidence fully, plus new studies have emerged contradicting many of the ea...
Source: Cannabis and PSTD Jun 10, 2020 3 years ago
Cannabis: According to a recent research led by Assistant Professor Dr Carrie Cuttle from the department of Psychology at Washington State University.
Individuals suffering from post-traumatic distress disorder (PSTD) report that cannabis reduces the severity of their symptoms by more than half, at least in the short term.
Dr Cuttler and the rest of the researchers analyzed data of more ...
Source: COVID-19 Drugs and Ivermectin Jun 10, 2020 3 years ago
COVID-19 Drugs: Medical Researchers from Broward Health Medical Center-South Florida, Drexel University College of Medicine and Florida International University have demonstrated that Ivermectin reduces mortality rates in hospitalized COVID-19 patients according to a cohort clinical study conducted. https://www.medrxiv.org/content/10.1101/2020.06.06.20124461v1.full.pdf+html
The study findin...
Weight Loss: New research findings in a study lead by Monash University’s Biomedicine Discovery Institute (BDI) that also included researchers from University of Kiel-Germany, University Of Melbourne, University Of Sydney, University Of New South Wales and University Of Copenhagen, have provided a new understanding into the roles two essential amino acids (threonine and tryptophan) play in m...
Source: COVID-19 And China Jun 09, 2020 3 years ago
COVID-19: Harvard University researchers have released a preprint study that states that the SARS-CoV-2 coronavirus was already in Wuhan as early as August 2019. https://dash.harvard.edu/bitstream/handle/1/42669767/Satellite_Images
_Baidu_COVID19_manuscript_preprint.pdf?sequence=1&isAllowed=y or https://dash.harvard.edu/handle/1/42669767
The study suggests that trends in hospita...
Probiotics: After a careful review and analysis of all available research publications and reports, the American Gastroenterological Association (AGA) has released new clinical guidelines that state for most digestive conditions there is not enough evidence to support the use of probiotics.
The AGA publication is the first clinical guideline to focus on probiotics across multiple GI disea...
US Medical News: There is beginning of some optimism as despite shutdowns being lifted and the ongoing protests in various states all over America with regards to criminal nature of the police force in the US, COVID-19 infections and deaths seem to be dropping.
In the last 24 hours, (8th June), there was only 19,044 new confirmed COVID-19 infected cases while there was only 586 COVID-19 r...
Source: Contraceptives And Weight Gain Jun 09, 2020 3 years ago
Contraceptives: Researchers from the University Of Colorado Anschutz Medical Campus say that genetics may explain why some women gain weight when using a popular method of birth control.
Dr Aaron Lazorwitz, an assistant Professor of Obstetrics/Gynecology and Family Planning at the University of Colorado School of Medicine and lead author of the study told Thailand Medical News, "For ...
Cataracts: A combined study by Australian and Chinese researchers involving more than 170,000 individuals show conclusive evidence that regular physical exercise reduces the risk of age-related cataracts.
Age-related cataracts are the cause of blindness in an estimated 13 million individuals worldwide.
The research findings published in the International Journal of Ophthalmolo...
Immune Health: As we age, our immune functions become dysfunctional or senescent while at the same time Influenza viruses and the SARS-CoV-2 coronavirus can wreak havoc on our bodies when we get infected especially with the body’s response of producing pro-inflammatory cytokines such as interleukin-6 (iL-6).
Medical research has since moved forward on several fronts ...
Source: Aspirin And Cancer Jun 09, 2020 3 years ago
Aspirin: A detailed meta-analysis by Italian researchers involving more than 113 past cancer studies indicates that by taking one or two aspirin doses a week helps ward off cancer, especially liver, stomach, pancreatic and bowel cancer. However they warned that while taking aspirin reduces the risk of cancer, it can increase the risk of ulcers and stomach bleeding and no one should ever start taki...
Source: Myocardial Injury Jun 09, 2020 3 years ago
Myocardial Injury: Medical researchers from Icahn School of Medicine at Mount Sinai have found that myocardial injury or heart damage is prevalent among patients hospitalized with COVID-19 and is associated with higher risk of mortality. More specifically, a serious myocardial injury can triple the risk of death.
Lead researcher Dr Anuradha Lala, MD, Assistant Professor of Medicine (Cardiology)...
SARS-CoV-2-associated acute kidney injury (AKI) is one of the more frequently encountered organ involvements in COVID-19, occurring in as many as 80% of all critically ill patients. A new French study shows that the SARS-CoV-2 coronavirus that causes the deadly COVID-19 disease, also attacks the proximal tubular cells of the kidney and causes the development of acute Fanconi syndrome as one of the...
Source: Kawasaki-Like Syndrome Jun 08, 2020 3 years ago
Kawasaki-Like Syndrome: Medical researchers from the University of Birmingham have developed a test that has offered evidence confirming COVID-19 to be the cause of a newly emerged multi-system inflammatory syndrome in children, who have tested negative for the virus by the PCR test.
The study findings also raise the possibility that children who may have had the virus in their system, ev...
Alzheimer: A first study by researchers from University Od Eastern Findland highlights the fact that individuals with Alzheimer’s disease using antiepileptic drugs have twice the risk of pneumonia compared to non-users.
The study showed that the risk was highest in the beginning of use, but remained on an elevated level even in long-term use. The results were published in the Journal of...
Source: COVID-19 Research Jun 08, 2020 3 years ago
COVID-19 Research: A European study involving more than 52 research centers, universities, medical schools and hospitals and more than a hundred researchers from a variety of countries has performed the first genome-wide association study to reveal host genetic factors that may contribute to respiratory failure in cases of COVID-19 disease including blood group types. It was found that those from ...
Source: Intermittent Fasting Jun 08, 2020 3 years ago
Intermittent Fasting: Medical researchers from Nottingham Trent University and Loughborough University have discovered why certain people do not lose weight while on an intermittent fasting program.
The study was published in the medical journal: Science Direct https://www.sciencedirect.com/science/article/abs/pii/S0195666319315636?dgcid=author
Typically intermittent fasting is a w...
Source: Cardiovascular Disease Jun 08, 2020 3 years ago
Cardiovascular Disease: Medical researchers from University of California, Berkeley, have discovered a correlation between disrupted nightly sleep and clogged arteries caused by inflammation, which could lead to serious heart and cardiovascular diseases.
The research findings are published in the medical journal: PLOS Biology https://journals.plos.org/plosbiology/article?id=10.1371/journa...
Source: COVID-19 Research Jun 08, 2020 3 years ago
COVID-19 Research: Medical researchers from Columbia University Irving Medical Center have found in a recent research study that lowering the hormone testosterone in infected patients could lessen the severity of COVID-19 disease by preventing the new SARS-CoV-2 coronavirus from entering lung cells.
The research findings which are published as a preprint have yet to have been peer reviewe...
Source: COVID-19 Long Term Effects Jun 07, 2020 3 years ago
COVID-19 Long Term Effects: As of 4am, California, Sunday 7th June 2020, the total official number of infected COVID-19 cases in the world has reached more than 7 million (7,001,2180) and total number of individuals who have died have reached 402,578.
These are only conservative figures as the real figures could actually be much more due to under reporting and concealments by government a...
Source: COVID-19 Research Jun 07, 2020 3 years ago
COVID-19 Research: To date, there are more than 1,486 peer-reviewed published research studies related to COVID-19 in more than 185 medical journals not only in English but also in other languages.
However there are almost more than 12,039 pre-print non-peer-reviewed studies published over the last few months in more than 17 pre-print servers online. Thailand Medical News in this second r...
Source: Uric Acid Supplements Jun 07, 2020 3 years ago
Uric Acid: Medical researchers from Kumamoto University in Japan have discovered that uric acid, an antioxidant, protects against declining lung function from age or lung disease, especially in women. https://www.mdpi.com/2076-3921/9/5/387
It is commonly known that the oxidant/antioxidant imbalance plays a pivotal role in the lung. Uric acid (UA), an endogenous antioxidant, is highly pres...
COVID-19 Latest: It was announce that the U S FDA has approved the antibiotic combination imipenem-cilastatin and relbactam (Recarbrio) for the treatment of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP) in patients aged 18 years and older. Recarbrio was previously FDA-approved to treat patients with complicated urinary tract infections and co...
COVID-19: It is shocking to see scenes of US authorities using tear gas and pepper sprays to disperse protesters in various states while the ongoing COVID-19 pandemic is still infecting tens of thousands of individuals each day. Studies have shown that the usage of these chemicals can increase the risk to respiratory illnesses. https://pubmed.ncbi.nlm.nih.gov/25003867/
Unknown to many des...
Cannabis: The world is facing an impending health crisis a bacterial resistance to antibiotics is growing at a fast rate. With fewer antibiotics available to treat resistant bacterial infections, the possibility of entering a pre-antibiotic era is becoming a fast reality.
Currently alternative strategies are being explored and helper compounds are attracting attention.
Helper compo...
US Medical News: America has finally started the legal process to sue a Chinese firm over half a million fake N95 masks that the country had ordered during the peak of the COVID-19 crisis when it needed these protective masks for its front line health staff.
A legal complaint was filed in a federal court in Brooklyn, New York, in which the FBI said Guangdong-based King Yea...
Blood Clots: Medical researchers from Baylor College of Medicine are recommending that all hospitalized COVID-19 patients especially those admitted to the ICU to undergo a thromboelastography (TEG) to test for the risk of forming blood clots.
The researchers advocated this protocol after after they found that more than half of the patients tested under these same conditions develope...
Source: COVID-19 Treatments Jun 06, 2020 3 years ago
COVID-19 Treatments: Significant early data from a clinical study suggest that blocking the Bruton tyrosine kinase (BTK) protein provided clinical benefit to a group of patients with severe COVID-19. The medical researchers observed that the off-label use of the cancer drug acalabrutinib, a BTK inhibitor that is approved to treat several blood cancers, was associated with reduced respiratory distr...
Campylobacter: According to a new research from the University of Queensland-Australia, gastrointestinal infection with Campylobacter plays a major role in the stunting of children.
The research findings are published in the medical journal: PLOS Neglected Tropical Diseases. https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0008328
Typical...
Source: Supplements And COVID-19 Jun 06, 2020 3 years ago
Supplements: Medical researchers from Singapore General Hospital lead by Professor Dr Heng Joo Ng from the Department of Hematology, SGH have recently published a preprint study that has been yet to be peer-reviewed that shows a combination of easily available and cheap dietary supplements such as Vitamins D3, B12 and the mineral magnesium can reduce the progression of the disease to severe or fat...
Source: Acute Kidney Injury Jun 06, 2020 3 years ago
Acute Kidney Injury: According to a study published in The British Medical Journal or BMJ, most hospitalized COVID-19 patients faced major morbidity and mortality, with 78.0 percent of those admitted to the intensive care unit (ICU) developing acute kidney injury or AKI. https://www.bmj.com/content/369/bmj.m1996
Dr Michael G. Argenziano, from Columbia University in New York City, and c...
US Medical News: There were a total of 22,268 New Covid-19 infections in the United States over the last 24 hours (4th June) and a total of 1031 deaths reported.
To date a total of 1,924,189 individuals have been infected with the SARS-CoV-2 coronavirus in the United States of which a total of 712,252 are supposedly to have ‘recovered’ according to US health authorities.
A to...
Source: High Blood Pressure Jun 05, 2020 3 years ago
High Blood Pressure: So far from what we have seen, diabetes and obesity are some of the many factors that contribute to the risk of dying from COVID-1 and now yet another study indicate that patients with raised blood pressure have a two-fold increased risk of dying from the coronavirus COVID-19 compared to patients without high blood pressure.
Furthermore the new research found th...
Women’s Health: A new study in the journal PLOS Pathogens by Dr Jo-Ann Passmore from the University of Cape Town, and her research teammates show that vaginal Lactobacillus bacterial strains largely perform better than strains currently used in probiotics for vaginal health. https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008559
The study findings su...
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