COVID-19 News: Spanish Researchers Warn That SARS-CoV-2 Infections And Vaccinations Trigger Reactivation Of All Kinds Of Herpesviridae Viruses!
: A new meta-analysis study involving the review of various published studies and case reports by researchers from Miguel Servet University Hospital, IIS Aragón-Spain has alarmingly found that SARS-CoV-2 infections and vaccinations trigger reactivation of all kinds of herpesviridae viruses! While it has already been known that COVID-19 and the related shots could trigger Herpes Simplex Virus (HSV) types-1 (HSV-1) and 2 (HSV-2) and Epstein-Barr Virus (EBV), the study findings showed that other kinds of viruses in the Herpesviridae family can also be reactivated including some that are cause more serious health complications.
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Ever since the start of the COVID-19 pandemic, numerous studies and case reports have highlighted a possible link between COVID-19 vaccination or infection and Herpesviridae co-infection or reactivation.
The study team conducted an exhaustive literature review on this topic, the results of which are presented individually for each member of the Herpesviridae family: Herpes Simplex Virus (HSV) types-1 (HSV-1) and 2 (HSV-2); Varicella-Zoster Virus (VZV); Epstein-Barr Virus (EBV); Cytomegalovirus (CMV); HHV-6; HHV-7; and HHV-8.
It should be noted that the reactivation of the Cytomegalovirus (CMV); HHV-6; HHV-7; and HHV-8. are very concerning as these viruses can cause many serious health complications.
According to the study team, these human herpesviruses can serve as prognostic markers for the COVID-19 infection and may even underlie some of the clinical manifestations initially attributed to SARS-CoV-2.
Besides SARS-CoV-2 infection, all corresponding vaccines approved to date in Europe appear capable of inducing herpesvirus reactivation.
The study team stresses that it is important to consider all viruses of the Herpesviridae family when managing patients infected with or recently vaccinated against COVID-19.
The study findings were published in the peer reviewed journal: Anais Brasileiros de Dermatologia.
Thailand Medical News in its previous COVID-19 News
coverages had already covered studies that showed SARS-CoV-2 infections were able to cause reactivation of some of these herpesviridae viruses.
While the reactivation of HH6 and EBV viruses have been associated with the chronic fatigue syndrome seen in many Post COVID or Long COVID individuals, the reactivation of some of the other herpesvirdae viruses such as cytomegalovirus (CMV) can have serious consequences on those infected with COVID-19.
To date, numerous cases of CMV reactivation in COVID-19 patients have been reported, some with fatal consequences.
Cytomegalovirus or CMV reactivation can manifest with a wide range of symptoms, including gastrointestinal bleeding and colitis, persistent fever, and secondary pneumonia, all of which are associated with a worse prognosis.
Cases of Herpes Zooster (HZ) or following the administration of SARS-CoV-2 vaccines have been reported worldwide. The largest series and narrative review include 399 cases, and another systematic review describes 91 cases of VZV reactivation following COVID-19 vaccination, counts lower than those who are registered in EudraVigilance.
The number of HZ cases associated with COVID-19 vaccines registered in the EudraVigilance database is 1410 for CX-024414, 9652 for Tozinameran, 3054 for CHADOX1 NCOV-19, and 205 for AD26.COV2.S.
The reactivation of Kaposi Sarcoma-Associated Herpesvirus (KSHV) is also another concern as it is an oncogenic virus and is the etiologic agent of several human cancers, including Kaposi Sarcoma (KS), primary effusion lymphoma, and multicentric Castleman’s disease. It is also associated with a hyperinflammatory syndrome named Kaposi sarcoma herpesvirus-associated inflammatory cytokine syndrome, which can be fatal in some patients.
The study team stressed that it is important to take into account these study findings and to consider all viruses of the Herpesviridae family when managing patients with COVID-19 infection or recently vaccinated against COVID-19.
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