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BREAKING NEWS
Arthritis
Arthritis is a broad term that covering more than a hundred different specific types of medical conditions afflicting the joints etc. Keep abreast with developing news about this broad medical ailment or its specific forms.
Source: Thailand Medical News  Jan 27, 2020  2 months ago
Individuals with osteoarthritis, or “wear and tear” arthritis, have limited treatment options: pain relievers or joint replacement surgery. Now, Salk researchers have discovered that a powerful combination of two experimental drugs reverses the cellular and molecular signs of osteoarthritis in rats as well as in isolated human cartilage cells. Their results were published in the journa...
Source: Thailand Medical News  Jan 22, 2020  2 months ago
A new study from Karolinska Institutet in Sweden, published in the scientific journal PNAS reports that endogenous proteins that play a vital part in allergies and parasitic infection can prevent the immune system from wrongly attacking the body and causing inflamed joints, The medical researchers hope that the results will give rise to new drugs for rheumatoid arthritis. Typically, i...
Source: Thailand Medical News  Jan 07, 2020  3 months ago
A simple treatment involving electrical nerve stimulation helped women with fibromyalgia in a recent clinical trial. The findings are published in Arthritis & Rheumatology. Typically, fibromyalgia is characterized by pain and fatigue, particularly during physical activity. Besides widespread pain, individuals with fibromyalgia also have sleep problems. Transcutaneous electrical nerve ...
Source: Thailand Medical News  Nov 20, 2019  5 months ago
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that can affect more than just your joints. In some people, the condition can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels. An autoimmune disorder, rheumatoid arthritis occurs when your immune system mistakenly attacks your own body's tissues. The condition is characterized by pain a...
Source: Thailand Medical News  Oct 28, 2019  5 months ago
A new study reveals that commonly given hip and knee steroid intra-articular injections may be harmful in some patients with at-risk conditions or may cause complications that are not well understood. Not only can these injections accelerate arthritis but they can cause joint destruction as well.   Boston University School of Medicine (BUSM) researchers have found accelerated arthritis and ...
Source: Thailand Medical News  Sep 30, 2019  6 months ago
Medical Thailand US FDA and other regulatory bodies in Europe and Canada are warning that Allopurinol and Febuxostat used to treat Gout found to be inked to rising number of cardiovascular and kidney incidences. Gout is a common type of arthritis that causes intense pain, swelling, and stiffness in a joint. It usually affects the joint in the big toe.   Gout attacks can come on quickly and k...
Source: Thailand Medical News  Jul 15, 2019  9 months ago
Rheumatoid arthritis is an autoimmune disease that occurs when immune cells attack the cartilage and bone of the joints. The disease affects roughly 1.4 percent of the global population. A common symptom is joint pain, but even before that, the body has started to produce immune antibodies against proteins in the joint. Scientists at Karolinska Institute in Sweden, have now discovered  how th...
Source: University of Virginia Health System  Feb 25, 2019  1 year ago
Researchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease. The discovery points to a potential new treatment for the autoimmune disorder and may also allow the use of a simple blood test to detect people at elevated risk for developing the condition. The pr...
Thailand Medical News  Feb 16, 2019  1 year ago
Twelve patients who tried injections of stem cells were hospitalized with infections, according to a report in the New York Times that should cause patients concern. More important is that they should investigate stem cell treatments, for conditions such as cartilage injuries to their joints, before committing to one of these procedures. It's also a valuable reminder that physic...
Source: Stanford University School of Medicine  Feb 06, 2019  1 year ago
In rheumatoid arthritis, immune cells called helper T cells behave differently from their counterparts in healthy cells and in other autoimmune diseases. Stanford scientists have learned why. Stanford University School of Medicine investigators succeeded in countering inflammation and tissue damage caused by rheumatoid arthritis in mice engrafted with human joint-lining tissue and...
Source: VIB (the Flanders Institute for Biotechnology)  Feb 04, 2019  1 year ago
Identical twin toddlers who presented with severe arthritis helped scientists to identify the first gene mutation that can single-handedly cause a juvenile form of this inflammatory joint disease. By investigating the DNA of individual blood cells of both children and then modelling the genetic defect in a mouse model, the research team led by Adrian Liston (VIB-KU Leuven) was able to unravel the ...
Source: Krembil Research Institute  Jan 15, 2019  1 year ago
Scientists at the Krembil Research Institute have developed a novel therapeutic treatment that has the potential to stop knee and spine osteoarthritis in its tracks. A team led by Principal Investigator Dr. Mohit Kapoor, Arthritis Research Director at UHN, published the results today in Annals of the Rheumatic Diseases in a paper titled "microRNA-181a-5p antisense oligonucleotide...
Source: Medical University of Vienna  Jan 01, 2019  1 year ago
A type of glycoproteins ie carbohydrate binding proteins, called galectins, plays an important role in the degeneration of cartilage in osteoarthritis. A research group at the Medical University of Vienna was able to demonstrate this correlation, in cooperation with international study partners. In osteoarthritis, certain galectins are produced by the cartilage cells themselves and accelerate the ...
Source: Washington University School of Medicine  Dec 07, 2018  1 year ago
People with autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis are at high risk of developing cardiovascular disease, even though none of these conditions seem to target the cardiovascular system directly. Now, researchers at Washington University School of Medicine in St. Louis believe they have begun to understand the link between the two. Researchers studying mice with a pso...
Source: Oregon Health & Science University,Portland  Nov 16, 2018  1 year ago
Results from a phase 3 clinical trial indicate that patients who have not benefited from standard therapy for ankylosing spondylitis (AS), a chronic inflammatory disease characterized by back pain and sacroiliac-joint damage, may have another treatment option in the biologic drug ixekizumab. The findings will be presented at the American College of Rheumatology's annual meeting in Chicago (Oct...
Source: Krembil Research Institute  Nov 03, 2018  1 year ago
Scientists at the Krembil Research Institute have developed a novel therapeutic treatment that has the potential to stop knee and spine osteoarthritis in its tracks.   A team led by Principal Investigator Dr. Mohit Kapoor, Arthritis Research Director at UHN, published the results today in Annals of the Rheumatic Diseases in a paper titled "microRNA-181a-5p antisense oligonu...
Source: Charité - Universitätsmedizin Berlin  Oct 24, 2018  1 year ago
An international research group led by Charité -- Universitätsmedizin Berlin has completed testing a new drug to treat rheumatoid arthritis. The drug is effective in patients with moderate to severe forms of the disease who have shown an inadequate response to conventional disease modifying drugs. Results from this research have been published in The Lancet. ABBVIE: Upadacitinib ...
Source: Case Western Reserve University  Aug 28, 2018  2 years ago
Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease (IBD), and arthritis.       The findings, published in Science Immunology, identify a chemical that potently inhibits inflammatory cell death. Cells often perforate their own membranes...
Source: Mount Sinai School Of Medicine  Aug 08, 2018  2 years ago
A new gene associated with disease severity in models of rheumatoid arthritis has been identified by researchers at the Icahn School of Medicine at Mount Sinai. The discovery could provide a new pathway for treatment and a way to measure the prognosis of patients diagnosed with the autoimmune condition. Through a series of experiments -- on synovial cells from the inner lining of joints in humans...
Source: University of Tsukuba   Jul 22, 2018  2 years ago
While many candidate citrullinated antigens have been identified in rheumatoid arthritis (RA) joints, their involvement in blood serum remains mostly uninvestigated. A new study from the University of Tsukuba-centered set out to explore the expression and commonality of citrullinated proteins in peptide glucose-6-phosphate isomerase-induced arthritis (pGIA) and patients with RA. The team also went...
Source: Multiple  Jul 21, 2018  2 years ago
In patients with chronic inflammatory conditions, such as rheumatoid arthritis, there has been limited understanding of how this inflammation affects the brain.   A new study published in Nature Communications examines this issue.   "Rheumatoid arthritis is an inflammatory and autoimmune condition with nasty levels of inflammation that can affect a person'...
Source: Multiple  Jul 20, 2018  2 years ago
Systemic lupus erythematosus (SLE) is a chronic disease that causes inflammation and tissue damage. SLE can involve many organs and systems and has a poor prognosis. It is one of a large group of autoimmune disorders, which occur when the immune system attacks the body's own tissues and organs.   Type I interferon (IFN-I), a key protein that regulates the immune system's activity, i...
Source: Multiple  Jul 19, 2018  2 years ago
Goal is vaccine that targets inflammation in joints     Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions. Such stem cells, known as SMART cells (Stem cells Modified for Autonomous Regenerative Therapy), develop into cartilage cells that produce a biologic anti-inflammatory drug that, idea...
Source: Zydus Cadila  Jul 19, 2018  2 years ago
Zydus Cadila gets USFDA approval for arthritis drug,Piroxicam.   Zydus Cadila has received final approval from the US health regulator for Piroxicam capsules, used for the treatment of osteoarthritis and rheumatoid arthritis. According to a BSE filing, Zydus Cadila will market Piroxicam Capsules USP in the strengths of 10 mg and 20 mg. The drug will be produced at the group’s manufa...
Staff Writer, TMN  Jul 09, 2018  2 years ago
Arthrogen, a biopharmaceutical company specializing in gene therapy, is now recruiting individuals with rheumatoid arthritis to test the new drug ART-I02.   Khun Nantida does not wear clothes with buttons. Most of her pants have waistbands and do not require zipping. She uses only electric toothbrushes because she cannot brush her teeth as efficiently on her own. When Khun Nantida cooks for...
Staff Writer, TMN  Jul 09, 2018  2 years ago
Currently, there is no cure for osteoarthritis, the most common joint problem in the United States. A new study brings hope of a single-injection fix. The drug on trial clears out old cells from the joints. Osteoarthritis (OA) is a type of arthritis that occurs when cartilage at the ends of bones wears down. It can affect any joint in the body, but it most commonly affects the hands, ne...

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