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HIV / AIDs
Read all about the latests in HIV/Aids research and treatment protocols and also developments made into various specific components of managing this disease that is by itself also evolving.
Nikhil Prasad  Mar 12, 2024  7 days ago
Medical News: The World Health Organization (WHO) recently released its 2024 HIV Drug Resistance (HIVDR) Report, shedding light on the concerning trend of increased resistance to dolutegravir, a key antiretroviral therapy for HIV. https://www.who.int/publications/i/item/9789240086319 Dolutegravir This Medical News report delves into the details of the report, highlighting its findings, impl...
James Rosh  Mar 10, 2024  9 days ago
HIV News: In a landmark move, Singapore has recently amended its Infectious Diseases Act, bringing about significant changes in the legal requirements for individuals living with HIV. The amendment, which was unanimously passed in Parliament on March 7th, no longer mandates people with HIV to inform their sexual partners of the risk of contracting the infection before engaging in sexual activity, ...
Nikhil Prasad  Mar 10, 2024  9 days ago
HIV News: In a groundbreaking discovery, a team of researchers from the University of Michigan has made significant strides in the fight against HIV, revealing a naturally occurring antiviral compound that holds the potential not only to treat but also to cure the elusive HIV virus. The compound, known as concanamycin A (CMA), was modified in the lab, paving the way for advanced lead compounds wit...
Nikhil Prasad  Jan 17, 2024  2 months ago
Pharma News: In the ever-evolving landscape of pharmaceutical litigation, Gilead Sciences has found itself embroiled in a protracted legal battle over its Tenofovir Disoproxil Fumarate (TDF)-based HIV drugs. The core of the dispute revolves around allegations of negligence, an unconventional approach where the focus is not on the inherent defects of the drug but on the purported delay in developin...
Nikhil Prasad  Jan 10, 2024  2 months ago
HIV News: The human immunodeficiency virus (HIV), has been a formidable adversary in the field of infectious diseases, owing much of its resilience to its high recombination rate. The ability to rapidly exchange genetic information between different viral strains has been a significant obstacle in developing effective treatments for HIV. A recent study by researchers from the University of Washing...
Nikhil Prasad  Dec 02, 2023  4 months ago
HIV News: In a significant leap forward in the ongoing battle against HIV, researchers at the Yale School of Medicine have recently revealed a detailed understanding of the intricate processes governing the early stages of HIV infection. Through the application of cutting-edge cryogenic electron tomography (cryo-ET), the study covered in this HIV News report, not only unraveled the complex interpl...
Nikhil Prasad  Nov 21, 2023  4 months ago
HIV News: In the persistent battle against HIV, researchers in Hong Kong have unveiled a groundbreaking breakthrough that holds immense promise for transforming HIV treatment. The focus of this revolutionary stride is Nicotinamide Mononucleotide (NMN), a novel agent that exhibits potential in the recovery of CD4+ T cells. Covered in this HIV News report, this comprehensive study provides a detaile...
Nikhil Prasad  Nov 03, 2023  5 months ago
Stem Cells News: Osteoarthritis (OA) is a debilitating condition that affects millions of people worldwide, resulting in extensive joint damage and chronic pain. Despite the continuous advancements in diagnosis, medications, and short-term pain management solutions, the development of a disease-modifying OA drug has remained a formidable challenge. However, in recent years, stem cell therapy is be...
Nikhil Prasad  Sep 26, 2023  6 months ago
HIV News: In a remarkable breakthrough, researchers at Johns Hopkins University have developed an innovative injectable hydrogel that has the potential to transform the treatment of HIV. This revolutionary hydrogel self-assembles under specific conditions and releases a controlled dose of the anti-HIV drug lamivudine over an extended period of six weeks. This development offers new hope to individ...
Thailand Medical News Team  Aug 24, 2023  7 months ago
HIV News: The global impact of the human immunodeficiency virus type 1 (HIV-1) has been immense, with over 39 million people living with HIV at the end of 2022. While antiretroviral medications have improved the lives of many infected individuals, HIV-1's ability to enter the central nervous system in around 80% of cases often results in neurodegeneration, giving rise to HIV-associated neuroco...
Thailand Medical News Team  Aug 10, 2023  7 months ago
HIV News: In a groundbreaking study published on August 10, 2023, in the prestigious journal Nature Communications, scientists have unveiled a novel and previously undiscovered route through which the human immunodeficiency virus (HIV) infiltrates the nucleus of healthy cells, thereby initiating a cascade of events that can lead to the replication of the virus and subsequent infection of other cel...
Thailand Medical News Team  Aug 06, 2023  8 months ago
HIV News: The fight against HIV has been ongoing for decades, but the virus remains a persistent global health challenge, affecting nearly 40 million individuals worldwide. Despite significant progress in treatment and access to therapies, HIV continues to impact millions of lives, with no vaccine or cure in sight. Latest HIV News reports show that HIV infections are rising once again due to compl...
TMN News Team  Aug 01, 2023  8 months ago
HIV News: Chile, a vibrant and diverse South American country, is facing a concerning surge in HIV cases, with health authorities reporting a 7% increase in infections in just one year. According to the Institute of Public Health (ISP), 5,401 new HIV cases were confirmed in 2022, leading to 644 associated deaths, while an estimated 84,000 people are living with the disease. The data reveals the hi...
Thailand Medical - HIV News   May 19, 2023  10 months ago
HIV News: In an unprecedented breakthrough, researchers from Temple University and the University of Nebraska Medical Center (UNMC) have successfully combined a dual gene-editing approach with antiretroviral therapy to effectively eliminate HIV infection in animal models. This potentially revolutionary treatment development, sets the stage for future research aiming at human trials, promising a si...
Medical News - Idiopathic CD4 Lymphocytopenia (ICL)  May 09, 2023  11 months ago
Medical News: A groundbreaking 11-year study led by the U.S. National Institute of Allergy and Infectious Diseases that was initiated by Dr Anthony Fauci Nation has exposed shocking insights into idiopathic CD4 lymphocytopenia (ICL), a rare and obscure immune deficiency that leaves individuals susceptible to a myriad of infectious diseases, autoimmune diseases, and cancers.   The study has ...
HIV News - HIV Genomes in Monocytes  Apr 12, 2023  11 months ago
HIV News: In the pursuit of HIV eradication, scientists have been examining various hiding places or reservoirs where the virus can store its genetic material. Recent research conducted by a team from Johns Hopkins Medicine has discovered evidence that HIV genomes can persist in a stable reservoir within circulating white blood cells called monocytes. This discovery may provide a new direction for...
HIV News  Apr 05, 2023  12 months ago
HIV News: A new subtype of HIV-1 has emerged, causing rapid decline in immune system function and increasing vulnerability to AIDS and has now been found to have spread globally!   Researchers have discovered a highly virulent variant of subtype-B HIV-1 circulating in the Netherlands, causing alarm in the medical community.   This new HIV strain, known as the "VB variant," is...
HIV News - Hopeaphenol - Viral Reservoirs  Mar 29, 2023  12 months ago
The Phytochemical Hopeaphenol , A Natural Stilbenoid, Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9   HIV News: A new breakthrough discovery in HIV research hold promise in enhancing the efficacy of current HIV treatments and improve the quality for individuals living with HIV.   Researchers from the Wistar Institute, Philadelp...
HIV News - Two Separate Latent HIV Resevoirs  Feb 01, 2023  1 year ago
HIV News: Researchers from the University Of North Carolina-United States have discovered that beside the CD4+ cells in blood and lymph tissues that serve as a reservoir for latent HIV, the T Cells in the CNS (Central Nervous System) are also another reservoir for latent HIV virus! This further adds to complications for researchers trying to find a cure for HIV.   Typically, when individual...
HIV News - U.S. FDA Approves Sunlenca (Lenacapavir) For Treatment Resistant HIV  Dec 30, 2022  1 year ago
HIV News: The U.S. FDA has of the 22nd of December 2022 granted approval to Gilead Sciences for the usage of its new drug, Sunlenca (Lenacapavir) to treat treatment resistant HIV. https://www.fda.gov/news-events/press-announcements/fda-approves-new-hiv-drug-adults-limited-treatment-options   Numerous recent HIV News coverages indicate that treatment resistant HIV is becoming a major problem...
HIV News -Long Lasting PrEP Injectables  Dec 01, 2022  1 year ago
HIV News: A new injectable PrEP to combat HIV infections and can last for two months has entered the market but unfortunately the cost of the drug was deliberately aimed at HISO sluts and upmarket prostitutes as it cost about US$3,800 per dose or over US$22,000 per person per year in the United States!   The new injectable PrEP called CAB-LA or cabotegravir-long acting was developed and pat...
HIV News - Heart Issues And HIV  Nov 29, 2022  1 year ago
HIV News: A new study review led by researchers from Kings College London British Heart Foundation Centre, School of Cardiovascular and Metabolic Medicine & Sciences -UK has found that HIV infections increase risk of cardiovascular issues!   The study team warned that HIV-associated cardiovascular disease is increasing in prevalence, but its mechanisms remain poorly understood.   T...
HIV News - SMC5/6  Nov 26, 2022  1 year ago
HIV News: A new study by researcher from Duke University Medical Center, Durham, North Carolina – USA have found that a protein complex called SMC5/6 allows HIV to evade antivirals and immunity.   To date, it is already known that after viral entry and reverse transcription, HIV-1 proviruses that fail to integrate are epigenetically silenced, but the underlying mechanism has remained ...
HIV News - Chronic Inflammation  Nov 23, 2022  1 year ago
HIV News: A new study by researchers from The George Washington University - USA, University of Melbourne - Australia and Massachusetts General Hospital, Harvard Medical School, Boston – USA have found that a HIV protein called Nef causes permanent changes to immune cells, leading to chronic inflammation and associated co-morbidities including cardiovascular issues.   According to the...
Source: Medical News - COVID-19 -HIV  Oct 14, 2022  1 year ago
A new study led by researchers from Johns Hopkins Bloomberg School of Public Health has found that HIV patients with moderately low CD4 cell counts risk severe breakthrough COVID-19 infections.   The study team said that understanding the severity of postvaccination SARS-CoV-2 (ie, COVID-19) breakthrough illness among individuals with HIV (PWH) can inform vaccine guidelines and risk-reducti...
Source: Medical News - Simian arteriviruses   Oct 05, 2022  1 year ago
A new U.S. NIH sponsored study has shockingly found that a primate hemorrhagic fever-causing arterivirus from Africa has acquired the necessary mutations to cross over into the human species using the CD162 receptors for cellular entry.   It should be noted that the African continent is a hub for various emerging pathogens and diseases and in fact, one theory that has not been properly expl...
Source: COVID-19 Induced Immunodeficiency  Jun 19, 2022  2 years ago
COVID-19 Induced Immunodeficiency: When Thailand Medical News as early as April 2020 warned and highlighted studies that SARS-CoV-2 infections could cause immunodeficiency conditions similar to those seen in HIV infections, we were ridiculed by many Western media and so called Western ‘garbage’ experts and even labelled as fake news by various America social media platforms! https:/...
Source: SARS-CoV-2 - HIV  Mar 30, 2022  2 years ago
A new study by researchers from University of Kansas Medical Center-USA has found that the envelope protein of SARS-Cov-2 potently inhibits HIV-1 infection! It has been found that the human coronavirus SARS-CoV-2 encodes for a small 75 amino acid transmembrane proteins known collectively as the envelope (E) protein.   The E protein forms an ion channel, like the viroporins from human immunod...
Source: HIV-VB Variant  Feb 04, 2022  2 years ago
VB HIV Variant: An international team of researchers led by Oxford University-UK And Stichting HIV Monitoring Research Institute-Netherlands have discovered an alarming new highly virulent HIV variant in Netherlands that is fast spreading around Europe. The new variant replicates faster causing high viral loads, attacks and depletes the CD4 cells more aggressively and rapidly, and was found t...
Source: SARS-CoV-2-HIV  Jan 15, 2022  2 years ago
SARS-CoV-2-HIV: Researchers from University of Chicago-USA and Northwestern University, Chicago-USA have in a new study uncovered the similarities and differences between SARS-CoV-2 And HIV-1 infections in terms of cellular and immune responses.   The key findings of the study show that:   -Both COVID-19 and HIV-1+ patients show disease-specific inflammatory immune signatures   -CO...
Source: Latest HIV News  Jan 12, 2022  2 years ago
A new study by researchers from the University of California Los Angeles (UCLA) has found that ApoA-I mimetic peptides, a type of anti-inflammatory and antioxidant peptides derived from tomato extract can reduce intestinal inflammation related to being infected with HIV. There is a dire need for novel therapeutic strategies are to attenuate increased systemic and gut inflammation that contribute ...
Source: Medical News - Omicron Updates  Dec 06, 2021  2 years ago
Omicron Updates: While many countries around the world are still seeing new winter surges due to the Delta variant and its emerging sub-variants, the Omicron variant has now been detected in a total of 43 countries around the world and is causing an increase of cases in Denmark, UK and US via local transmissions.   In France, the Delta variant is now causing a surge due to the emergence of n...
Source: SARS-CoV-2 Mutations-Immune Evasion  Oct 25, 2021  2 years ago
SARS-CoV-2 Mutations-Immune Evasion: A new study by researchers from the Data Science Department, SOPHiA GENETICS-Switzerland has found that mutations at a hotspot W152 of the N-Terminal Domain (NTD) of the SARS-CoV-2 virus is driving immune evasion.   The study team reported a striking increase in the frequency of recruitment of diverse substitutions at a critical residue (W152), positioned...
Source: HIV-COVID-19  Jul 10, 2021  3 years ago
HIV-COVID-19: Numerous case studies are emerging that special attention needs to be paid to HIV patients should they contract the COVID-19 disease as their immunocompromised conditions make them perfect ‘vivo laboratories’ for the SARS-CoV-2 to constantly mutate and develop more potent and worrisome mutations and resultant variants. In one case study published on a preprint server by ...
Source: HIV News  Jan 17, 2021  3 years ago
HIV News: A new international study led by the University of Southern California, involving various other research entities including University of Cape Town-South Africa,Thai Red Cross AIDS Research Centre-Thailand, University of Amsterdam-Netherlands, Washington University School of Medicine-USA, Missouri University of Novi Sad-Serbia ,University of New South Wales-Australia, University of Calif...
Source: HIV News  Dec 15, 2020  3 years ago
HIV News: A new collaborative international HIV study has shown that Dolutegravir, the current first-line treatment for HIV, may not be as effective as hoped in sub-Saharan Africa. The research finds that this so-called 'wonder drug' may be less effective in patients resistant to older drugs.   The research findings were published in the peer reviewed journal: Nature Communications. ...
Source: HIV News  Oct 19, 2020  3 years ago
HIV News: University of British Columbia researchers have concluded a new study of which the findings are set to change international treatment recommendations for individuals who are newly diagnosed with HIV, an update that could affect nearly two million people per year worldwide.   The research found that the antiviral dolutegravir is the optimal medication for first-line treatment for i...
Source: HIV Drugs  Sep 23, 2020  4 years ago
HIV Drugs: According to researchers from the University of Washington-Seattle, the commonly used HIV drug that is to treat those infected and also individuals using it as a prophylaxis or in PrEP protocols can induce a type I/III interferon-associated signature and inflammation throughout the gut.   It should be noted that long term inflammation of any kind can lead to a variety of chronic ...
Source: HIV News  Sep 08, 2020  4 years ago
HIV News: Researchers from University of Michigan Health System have discovered that a class of antibiotics called pleicomacrolides allows the immune system to kill HIV infected cells by inhibiting the Nef proteins.   The research finds are published in the Journal of The Proceedings of the National Academy Of Sciences of The United States Of America (Concanamycin A counteracts HIV-1 Nef to...
Source: HIV News  Aug 23, 2020  4 years ago
HIV News: The trend for HIV drug research is now shifting towards drugs with long lasting effects without the need for HIV patients to adhere to stringent daily regimens and doses which can be quiet stressful at times.   Scientists from the University of Utah Health in collaboration with researchers from the National Institute of Allergy and Infectious Diseases (NIAID), Beth Israel Deacones...
Source: HIV Drug News  Aug 15, 2020  4 years ago
HIV Drug News: Researchers at the George Washington University in a new study have discovered that Fingolimod, a US FDA-approved immunosuppressive drug used to treat multiple sclerosis flare-ups, may be used to effectively block HIV infection and reduce the latent virus reservoir.   The research findings were published in the journal: PLOS Pathogens. https://journals.plos.org/plospathogens/...
Source: HIV Research  Aug 02, 2020  4 years ago
HIV Research: The significant impact and prevalence of heart disease and other critical comorbidities on an aging global population with human immunodeficiency virus (HIV) have emerged from a suite of articles in The Journal of Infectious Diseases that contains the first swath of important data from the world's largest study of cardiovascular disease (CVD) prevention in people with H...
Source: COVID-19 And HIV  Jul 05, 2020  4 years ago
COVID-19 And HIV: Individuals with HIV who were hospitalized with COVID-19 did not have worse results than COVID-19 patients without HIV, according to new research by Icahn School of Medicine at Mount Sinai.   The research findings were published in the journal: Clinical Infectious Diseases https://academic.oup.com/cid/article/doi/10.1093/cid/ciaa880/5864410?searchresult=1   Study...
Source: HIV Drugs  Jul 04, 2020  4 years ago
HIV Drugs: The drug Rukobia (fostemsavir) has been approved by The U.S. FDA for adults living with HIV who have tried multiple HIV medications and whose HIV infection cannot be successfully treated with other therapies because of resistance, intolerance or safety considerations. Rukobia (Fostemsavir) is a new type of antiretroviral medication to be taken twice daily by mouth. It is a prodrug, whi...
Source: HIV and Lenacapavir  Jul 02, 2020  4 years ago
HIV and Lenacapavir: Gilead scientists are reporting an early step toward an HIV drug that could potentially be taken only a couple of times per year.   A new study showed that a single injection of the experimental drug, called lenacapavir, was able to lower blood levels of HIV in a small group of patients. And it was capable of maintaining active levels in the blood for more than six...
Source: Thailand HIV  Jun 21, 2020  4 years ago
HIV: Immunology researchers from the Yerkes National Primate Research Center and the Emory Vaccine Center (EVC) are first to show a new adjuvant, 3M-052, helps induce long-lasting immunity against HIV.   The research findings are published today in the journal: Science Immunology. https://immunology.sciencemag.org/content/5/48/eabb1025   Significantly, in this pre-clinical study&n...
Source: Thailand HIV  Jun 12, 2020  4 years ago
HIV: Medical researchers from Rush University Medical Center, Temple University School of Medicine and the University Of Texas Medical Branch have found that astrocytes, a type of brain cell can harbor HIV and then spread the virus to immune cells that traffic them out of the brain and into other organs.   It was observed that HIV moved from the brain via this route even when the virus was ...
Source: HIV Research  May 09, 2020  4 years ago
HIV Research: Medical researchers have known for a long time that despite the advancements in antiretroviral therapy, varying amounts HIV virus remains in infected individuals forever, hiding in small reservoirs of cells of the immune system. Should ever these individuals discontinue the antiretroviral therapy, the HIV virus almost always rebounds rapidly from the reservoirs, causing deadly sympto...
Source : Thailand Medical News  Feb 19, 2020  4 years ago
Non-alcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease (NAFLD) and is characterized by liver inflammation and cell damage. It is a potentially dangerous condition that can progress to cirrhosis or liver cancer. Unfortunately, HIV patients tend to have a high prevalence of the disease.   A new study by McGill University, Canada has found that Vitamin E can ...
Source: Thailand Medical News  Feb 01, 2020  4 years ago
Typically antiretroviral drugs are the gold standard for the treatment of HIV infection. They are highly effective in suppressing replication of the virus but require lifelong daily application and can be associated with side effects. Due to the high mutability of HIV and its capacity for rapid adaptation, combinations of antiretroviral agents are required to prevent the development of drug resist...
Source: Thailand Medical News  Jan 23, 2020  4 years ago
More than 42 million people are infected with HIV worldwide, about 1.5 million people in the United States alone. Currently, people with HIV take antiretroviral therapy (ART), which can suppress HIV to undetectable levels in blood, but the virus persists throughout the body in latently infected resting CD4+ T cells. The immune system cannot recognize these cells and no current therapies can elimin...
Source: Thailand Medical News  Jan 09, 2020  4 years ago
A research discovery by Florida State University College of Medicine researchers is expected to open the door for new and more potent treatment options for many of the more than 45 million people worldwide infected with the HIV virus and for others chronically ill with hepatitis B. Professor Dr Zucai Suo of the FSU College of Medicine. Credit: Colin Hackley/FSU Their study has established for t...
Source: Thailand Medical News  Jan 07, 2020  4 years ago
New nonhuman primate research suggests for the first time that a single dose of an antibody-based treatment can prevent HIV transmission from mother to baby. The findings are being published in the journal Nature Communications. The time or period when that single dose is given is key, however. The study found rhesus macaque newborns did not develop the monkey form of HIV, called SHIV, whe...
Source: Thailand Medical News  Dec 18, 2019  4 years ago
Despite early antiretroviral therapy, or ART, has ensured less deadly outcomes for children living with and exposed to HIV, studies show the virus still may affect the brain. HIV may disrupt neurodevelopment, affecting how children learn, reason and function. Dr Michael Boivin, professor and director of the Psychiatry Research Program in the Michigan State University College of Osteopathic Medi...
Source: Thailand Medical News  Dec 12, 2019  4 years ago
A study of human cells and tissues by researchers at the National Institutes of Health and the University of Bologna, Italy has shown that Nano-sized vesicles released by certain bacteria that inhabit the vagina may protect against HIV infection. Typically known as extracellular vesicles, these bubble-like particles are produced by many kinds of cells and are thought to transport molecules...

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