Source: Medical News - Povidone Nasal Sprays For COVID-19 Aug 24, 2022 1 month ago
A study by researchers from Mahidol University, Siam University and Samut Sakhon Hospital has found that 0.4% povidone-iodine nasal spray is not the least effective as a prophylaxis to prevent SARS-CoV-2 infections.
During the initial phases of the SARS-CoV-2 pandemic, numerous Indian scammers and Indian run companies were promoting various Povidone-iodine nasal sprays products as prophyl...
Source: Medical News - COVID-19 Drugs - Metformin Aug 22, 2022 1 month ago
COVID-19 Drugs: A randomized clinical trial involving 1431 non-hospitalized patients showed that metformin reduced the risk of COVID-19 severity and risk of COVID-19 mortality.
The randomized double-blinded placebo- controlled trial by conducted by the COVID-OUT consortium that is led by researchers from University of Minnesota and also involved medical scientists from the UnitedHealth Gro...
Source: Medical News - COVID-19 Drugs -Remdesivir Aug 13, 2022 2 months ago
COVID-19 Drugs: A new study by Japanese researchers from Tohoku University, Kyushu University, Okayama University and the National Institutes of Natural Sciences, Okazaki-Japan has alarmingly found that the U.S. FDA approved and heavily promoted drug for COVID-19 ie Remdesivir activates the urotensin II receptor and induces cardiomyocyte dysfunction that can lead to heart issues that can also end ...
COVID-19 Drugs: The World Health Organization has strongly advised against the usage of two drugs to treat non-severe COVID-19, ie the antidepressant drug fluvoxamine and the gout drug colchicine.
The WHO said that both drugs were not recommended for patients with mild or moderate COVID-19 because there is currently insufficient evidence that they improve important outcomes for patients, and both...
COVID-19 Drugs: A new study by medical researchers from Stanford University-California has found that the commonly available and cheap generic drug, Spironolactone (Aldactone) improves clinical outcomes especially in severe COVID-19 infections.
Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liv...
Source: COVID-19 Drugs-Paxlovid Jun 16, 2022 3 months ago
In a surprising move, the American big pharma company that is a major supporter of the Biden administration…Pfizer Inc on Tuesday announced that it would halt enrollment in a clinical trial for its claimed COVID-19 antiviral COVID-19 drug-Paxlovid, in standard-risk patients after data analysis showed a non-significant reduction in hospitalizations and deaths.
Typically, the standar...
Source: COVID-19 Drugs - Nirmatrelvir & Paxlovid Jun 10, 2022 4 months ago
COVID-19 Drugs: A new study by researchers from the Copenhagen University Hospital-Denmark, the Department of Immunology and Microbiology at the University of Copenhagen-Denmark and the Technical University of Denmark has found that the mutations E166V and L50F+E166V that are found on various emerging SARS-CoV-2 variants, weakens nirmatrelvir-Mpro binding. Nirmatrelvir, an oral protease inhibitor ...
Source: COVID-19 Drugs - Clofoctol May 30, 2022 4 months ago
COVID-19 Drugs: A new study by researchers from the University of Lille-France, the Institut Pasteur de Lille-France, the Center for Infection and Immunity of Lille-France, CNRS, INSERM, and CHU Lille0France has found that the existing antibiotic Clofoctol could be repurposed to treat COVID-19.
Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nos...
Source: COVID-19 Drugs - Viagra - Sildenafil May 18, 2022 4 months ago
COVID-19 Drugs: A new study by researchers from the University College London-UK, Imperial College London and the Royal Brompton Hospital-UK has found that the drug Viagra can be used to treat COVID-19 related pneumonitis and moderate to severe ARDS.
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hyperte...
COVID-19 Drugs: Researchers from the Indian Institute of Science, India has found that the asthma drug Montelukast (Singulair) can block the SARS-CoV-2 non-structural protein 1 (Nsp1,) which in turn results in the inhibition of SARS-CoV-2 replication, showing it prowess as potential COVID-19 drug!
Montelukast is a drug used in the maintenance treatment of asthma that is marketed under the trade n...
Source: SARS-CoV-2-Minocycline Apr 23, 2022 5 months ago
SARS-CoV-2-Minocycline: News has emerged that China is now using the antibiotic drug Minocycline to treat COVID-19 cases in various cities across China including Shanghai despite lack of published clinical trial studies showing its efficacy.
Chinese researchers from the Chinese Academy of Medical Sciences & Peking Union Medical College along with scientists from the Inner Mongolia Medical Un...
We at Thailand Medical News think that urgent studies are needed by independent and credible researchers with regards to Pfizer’s Paxlovid as there are many now many unpublished case reports by both physicians and also patients reporting anomalies when the so-called antiviral drug is used to treat COVID-19 patients.
One common occurrence being reported is that many when tested posit...
Source: Medical News - NAC Apr 14, 2022 6 months ago
Yet another worrisome study finding has emerged that adds to the growing list of human host cellular and biological pathways… now numbering in hundreds, that are dysregulated or disrupted by the SARS-CoV-2 coronavirus with implications for long term medical and health issues, some that can end up with fatal outcomes.
Already Thailand Medical News has issued numerous warnings that m...
Source: Thailand Medical Apr 01, 2022 6 months ago
No this is not some April Day prank nor it is some fear porn to get everyone anxious, rather this is stark warning that everyone who has been exposed to the proteins of the SARS-CoV-2 virus through whichever means need to take it upon themselves to do frequent medical checkups and also to take necessary precautions and also to seek out treatment protocols to self-treat themselves as even the...
Source: COVID-19 Drugs - Aspirin Mar 25, 2022 6 months ago
COVID-19 Drugs: A new cohort study by researchers from George Washington University-USA has demonstrated that aspirin use is associated with reduced risk of mortality in hospitalized moderate COVID-19 patients.
Previous observational studies already showed that aspirin use may be associated with reduced mortality in high-risk hospitalized patients with COVID-19, but aspirin’s effica...
Source: COVID-19 Drugs - Famotidine Mar 02, 2022 7 months ago
COVID-19 Drugs: The study findings of a phase 2 clinical trial led by Feinstein Institutes for Medical Research-New York and Cold Spring Harbor Laboratory shows that the common heart burn drug Famotidine is effective in treating COVID-19 disease especially for those with in mild to moderate cases.
It should be noted that Thailand Medical News first reported on the potential of using famot...
Pharma News: Fake molnupiravir pills under a variety of brandnames are appearing not only on various illegal online sites that are selling controlled medications but also in many pharmacies around the world that are known to also sell controlled drugs illegally and also in the various notorious drug ‘black-market retail sites’.
It was reported that only after a week in January when mo...
Source: COVID-19 Drugs-Kasugamycin-FRG Jan 30, 2022 8 months ago
COVID-19 Drugs: Scientists from Brown University-Rhode Island have found that that Chitinase 3-Like-1 (CHI3L1) inhibitors stops replication of the SARS-CoV-2 coronavirus including the Omicron and Delta variants in the human host.
Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 g...
Source: Calcium Channel Inhibitors-SARS-CoV-2 Jan 20, 2022 8 months ago
Calcium Channel Inhibitors-SARS-CoV-2: A new study by researchers from the Institute of Biophysics, Johannes Kepler University Linz-Austria has found that calcium channel inhibitors including existing drugs such as amlodipine, nifedipine, felodipine, verapamil and the phytochemical neferine from the lotus plants can possibly treat SARS-CoV-2 infections.
Strategies for inhibition of cellular ...
Source: SIRT5 Inhibitors As Potential COVID-19 Drugs Jan 11, 2022 9 months ago
A new study by researchers from Buck Institute for Research on Aging-California, Gladstone Institute-California, University of California-San Francisco and the QBI COVID-19 Research Group (QCRG)-California has revealed that the SARS-CoV-2 coronavirus can be inhibited and controlled by downregulating human host SIRT5. The study findings showed that SIRT5 is a proviral factor and that SARS-CoV-2 lev...
Source: COVID-19 Drugs - Ramatroban Jan 03, 2022 9 months ago
COVID-19 Drugs: A small clinical study conducted by researchers from the Charak Foundation-California-USA, Regulatory Wisdom-India, the EyeSight Eye Hospital and Retina Centre-India and the University of California Irvine-USA has found that the drug Ramatroban, which is a thromboxane A2 & prostaglandin D2 receptor antagonist can be used to treat COVID respiratory distress and hypoxem...
Source: COVID-19 Prophylactics-Therapeutics Dec 14, 2021 10 months ago
COVID-19 Prophylactics-Therapeutics: Scientist from Friedrich-Alexander University Erlangen-Nürnberg-Germany, Ulm University Medical Center-Germany, University Hospital Tübingen-Germany and Marinomed Biotech AG-Austria have in a new study found that the safe and non-toxic natural compound iota-carrageenan has the ability to inhibit replication of all existing SARS-CoV-2 variants of ...
Source: COVID-19 Drugs - Calcium Channel Blockers Dec 12, 2021 10 months ago
COVID-19 Drugs: A new study by researchers from Cornell University -New York has found that that entry of coronaviruses such as SARS-1, MERS and even SARS-CoV-2 is a Ca2+-dependent process. The study findings also propose that existing FDA approved calcium channel blockers could be repurposed as potential COVID-19 drugs.
We are making a special appeal to all readers to please help to sustain this...
COVID-19 Drugs: A new study by scientists from the University of Florida-USA and the University of Saskatchewan has found that the common over-the-counter antihistamine diphenhydramine when paired with the commonly available supplement lactoferrin, a protein found in cow and human milk, the pair had the capability to hinder the SARS-CoV-2 virus during tests in monkey cells and ...
SourceL COVID-19 Drugs - Molnupiravir Dec 05, 2021 10 months ago
COVID-19 Drugs: Updated data on molnupiravir shows the drug reduces hospitalization or death by 30%, down from the initially reported 50% efficacy.
Last week Merck has provided updated data on its COVID-19 antiviral, molnupiravir, that shows the antiviral to be significantly less effective against the virus than previously thought. https://www.merck.com/news/merck-and-ridgeback-biotherapeutics-p...
Source: COVID-19 Drug Scams-Favipiravir Nov 29, 2021 10 months ago
Since the beginning of the pandemic, certain countries like China and Japan were advocating the use of Favipravir (Avigan) to treat COVID-19 despite lack of evidence to show its efficacy. Surprisingly, although China was advocating its use to other countries by giving and selling stocks of the drug, it was never really endorsed in its own national guidelines for COVID-19 treatment neither was it u...
Source: COVID-19 Prophylactics-Therapeutics Nov 26, 2021 10 months ago
COVID-19 Prophylactics-Therapeutics: Researchers from the University of Tennessee Health Science Center-USA and Instituto de Ciencia y Tecnología-Argentina have in a new study demonstrated that a combination of iota-carrageenan and xylitol inhibit SARS-CoV-2 in Vero cell culture, paving the way for the development of a prophylactic and therapeutic nasal spray for COVID-19.
Since the...
COVID-19 Drugs: University of California-San Francisco and Stanford University researchers have in a new study involving the meta-analysis of health records from 87 health care centers across America found that individuals taking a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs), especially Fluoxetine or Fluvoxamine were significantly less likely to die of COVID-19 ...
Source: Medical News-COVID-19 Drugs Nov 14, 2021 11 months ago
COVID-19 Drugs: A new study by Austrian researchers from the Medical University of Vienna, Kaiser Franz Josef Hospital, University of Innsbruck and the Johannes Kepler University-Austria has found that not only does the anticoagulant-low molecular weight Heparin reduces the risk of disease severity and mortality about those with COVID019 but it also curtails the duration of the SARS-CoV-2 Infectio...
Source: COVID-19 Treatments - Hydrogen Nov 13, 2021 11 months ago
COVID-19 Treatments: Researchers from Tianjin Medical University General Hospital-China and Weifang Medical University-China are exploring the usage of hydrogen therapy as a possible adjuvant treatment for COVID-19.
COVID-19 is an acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has no specific and effective treatment to date except ...
COVID-19 Drugs: A new COVID-19 drug breakthrough study led by researchers from the Department of Infectious Diseases, Konkuk University-Gwangjin-gu-South Korea along with help from Chung-Ang University- Gyeonggi-South Korea has demonstrated that the pharmaceutical product called Hemin can be used to treat COVID-19 via heme oxygenase-1 Induction.
The antiviral effects of heme oxygenase-1 (HO-1), a...
Source: SARS-CoV-2 Antivirals Nov 08, 2021 11 months ago
SARS-CoV-2 Antivirals: Maybe as a result of an oversupply of Pacific oysters due to a trade spat with China, Australians are desperate to find alternative uses for their oysters or maybe there is some scientific basis after all since a study has been published in the peer reviewed journal: Reviews In Medical Virology, showing the possible benefits of hemoplymph from Pacific oysters (Crassostrea gi...
Fluvoxamine-COVID-19: The results from the TOGTHER clinical trial has shown that fluvoxamine reduces the risk of COVID-19 disease severity and reduces the need for hospitalization.
The TOGETHER trial is a randomized, adaptive platform trial to investigate the efficacy of repurposed treatments for COVID-19 disease among high-risk adult outpatients. The trial was designed and done in partner...
Source: Autophagy-SARS-CoV-2 Oct 26, 2021 11 months ago
Autophagy-SARS-CoV-2: A review published by a researcher, Dr Theo Rein from the Max Planck Institute of Psychiatry, Munich-Germany in the peer reviewed Journal of Cellular Biochemistry highlights the importance of autophagy in the fight against SARS-CoV-2 infections and also identifies potential drugs that could be repurposed to treat COVID-19. https://onlinelibrary.wiley.com/doi/10.1002/jcb.30166...
COVID-19 Drugs: A new multinational research involving medical scientists from Aarhus University-Denmark, Istituto Pasteur Italia-Cenci Bolognetti Foundation-Italy, University of Ottawa-Canada and Ottawa Hospital Research Institute-Canada has found that the U.S, FDA approved antimicrobial drug Atovaquone has antiviral potential against the SARS-CoV-2 coronavirus and emerging VOCs and could be repu...
Source: Antithrombotics-COVID-19 Oct 21, 2021 11 months ago
Antithrombotics-COVID-19: A new multi-institutional clinical study has shown that antithrombotic therapy involving drugs like aspirin or apixaban is not warranted in COVID-19 outpatients.
The researchers from Brigham and Women’s Hospital-Massachusetts, University of Pittsburgh-Pennsylvania, University of Illinois-Chicago, Intermountain Healthcare-Utah, National Heart, Lung, and Blood Instit...
COVID-19 Drugs: A new multinational retrospective cohort study by researchers from Penn State College of Medicine, Pennsylvania-USA shows that glucose-regulating medications used to treat obesity and type-2 diabetes may improve outcomes in COVID-19 patients with type-2 diabetes.
It has already been known that individuals with type 2 diabetes mellitus (T2DM) are at increased risk of severe COVID-1...
COVID-19 Drugs: A new study that analyzes real-world data utilizing artificial intelligence by researchers from AdventHealth Research Institute-Orlando, Oak Ridge National Laboratory-Tennessee and the University of Tennessee has found that the antiemetic drug Zofran (Ondansetron) lowers risk of mortality of severe COVID-19 patients on ventilators and is associated with increased survival of these ...
Source: Monoclonal Antibodies-SARS-CoV-2 Variants Oct 07, 2021 12 months ago
Monoclonal Antibodies-SARS-CoV-2 Variants: If anything, the COVID-19 pandemic has revealed to those intelligent enough to understand anything that the elites in the United States are nothing more than the most filthy, unethical and greedy and corrupted live forms ever to emerge this earth.
From day one of the pandemic, certain American elites have been controlling the narratives of the COV...
COVID-19 Exposé : First it was the Trump Administration along with the U.S.NIH or to be specific the NIAID headed by Anthony Fauci that poured millions of dollars in to the development and research of the overpriced drug remdesivir that is not only hepatoxic but also nephrotoxic to treat COVID-19. There are tons of studies that confirm its toxicity issues, these are just a few.
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COVID-19 Drugs: A researcher from the University of Lahore Pakistan has proposed that the drug aprepitant could be used to target the neurokinin-1 receptors to prevent COVID-19 cytokine storms.
Aprepitant is a medication used in the management and treatment of chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV). It is in the neurokinin-1 a...
COVID-19 Drugs: The phase 1a clinical trial led by researchers from the University of Liverpool-UK using the antiparasitic drug Nitazoxanide has shown potential in terms of treating the COVID-19 disease. The research team also comprised clinicians and scientist from University of Southampton-UK, University of Cambridge-UK, the Liverpool School of Tropical Medicine-UK and the Liverpool University H...
Source: COVID-19 Drugs-Fluvoxamine Sep 06, 2021 1 year ago
COVID-19 Drugs: Results from the TOGETHER multi-institutional, multi-country randomized platform clinical trials of various repurposed drugs to treat COVID-19 has shown that treatment with fluvoxamine (100mg twice daily for 10 days) among high-risk outpatients with early diagnosed COVID-19, reduced the need for extended emergency room observation or hospitalization.
The institutions ...
COVID-19 Drugs: Researchers from the University of California-San Francisco along with support from Stanford University are exploring the use of the abortion drug Ethacridine to inhibit SARS-CoV-2 by inactivating viral particles and to assess its potential as a prophylaxis and also therapeutic agent to treat COVId-19.
Their study findings were published in the peer reviewed journal: PLOS Pathogen...
Source: Pulmonary Fibrosis Sep 01, 2021 1 year ago
A new breakthrough study by researchers from University of Alabama at Birmingham-USA has found that the drug Venetoclax used to treat adult patients with Chronic Lymphocytic Leukemia (CLL) could be repurposed to reverse lung fibrosis after successful mouse model drug trials.
Venetoclax, sold under the brand names Venclexta and Venclyxto, is a medication used to treat adults with chronic lymp...
Researchers from the Centro Nacional de Investigaciones Cardiovasculares (CNIC)-Spain and the IIS-Fundación Jiménez Díaz University Hospital-Spain have in a new clinical study discovered that metprolol- a cheap drug widely used to treat cardiovascular disease, is beneficial in treating severely ill COVID-19 patients.
Metoprolol, sold under the brand name Lopressor, amo...
COVID-19 Drugs: A detailed meta-analytical study by researchers from the University of Virginia-USA, Humboldt-Universität zu Berlin-Germany, Freie Universität-Germany and Berlin Institute of Health, of previous research findings including clinical trials has revealed that the heartburn drug famotidine used alongside Aspirin has the potential to prevent disease severity a...
Source: COVID-19 Drugs-Fluvoxamine Aug 14, 2021 1 year ago
COVID-19 Drugs: Fluvoxamine, an inexpensive anti-depressant drug is now emerging as a potential candidate to be repurposed to treat COVID-19.
Speculations are adrift that Canada might be the first country to approve its usage to treat COVID-19 followed by the United States, India, Brazil and South Africa.
Fluvoxamine, sold under the brand name Luvox among others, is an antid...
Despite so many small randomized clinical trials and observational studies that showed Ivermectin could be used to treat COVID-19 during the early stages of the COVID-19 pandemic, physicians, researchers and individuals should stop attempting to treat COVID-19 with Ivermectin as the drug as no efficacy against most of the new variants that are currently dominating various countries.
Thailand Medi...
Source: COVID-19 Therapeutics Aug 09, 2021 1 year ago
COVID-19 Therapeutics: A new research led by scientists from Yale University along with other experts from University of Minnesota and Iowa State University has found that a crucial enzyme known as the Coronavirus 3′–5′ exoribonuclease (ExoN) promotes antiviral resistance hence making many identified drugs such as remdesivir, ivermectin and even identified antiviral phytochemical...
COVID-19 Drugs: A new mouse based vivo study by researchers from the Scripps Research Institute-California along with scientist from the University of Texas and Sorrento Therapeutics Inc.-California have found that salicylanilides which are active pharmaceutical ingredients (APIs) found in drugs used to treat tapeworm infestations demonstrated efficacy in terms of inhibiting the SARS-CoV-2 coronav...
COVID-19 Drugs: Scientists from the University of Birmingham and Keele University in the UK and the San Raffaele Scientific Institute in Italy have demonstrated that the licensed cholesterol lowering drug fenofibrate and its active form (fenofibric acid) can significantly reduce SARS-COV-2 infection in human cells in the laboratory. Importantly, reduction of infection was obtained using conce...
COVID-19 Drugs: A new in vitro study conducted by researchers from University of Georgia-US and Shahid Beheshti University-Iran has found that the common high pressure drug called Losartan is able to inhibit SARS-CoV-2 coronavirus replication.
Losartan, sold under the trade name Cozaar among others, is a medication mainly used to treat high blood pressure. Losartan belongs to a gr...
Source: miRNAs and SARS-CoV-2 Aug 02, 2021 1 year ago
COVID-19 Therapeutics: Researchers from Gujarat University inspired by Thailand Medical News call to focus on Phytochemicals and microRNAs as solutions to containing the SARS-CoV-2 pandemic have in a new study utilizing computational workflow, identified potential cellular miRNA candidates that are potent in providing antiviral defense against SARS-CoV-2 infection.
The study team designed a syste...
Source: COVID-19 Drugs-Budesonide Jul 29, 2021 1 year ago
Another study finding has emerged proving the antiviral effects of Budesonide when used either as an inhaler or as a nasal spray.
German researchers from the Ruhr-University Bochum and also from the European Virus Bioinformatics Center (EVBC) based in Jena-Germany have in a new study confirmed the viral effects of Budesonide against the wildtype SARS-CoV-2 coronavirus and even against the ...
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