COVID-19 Research: A new research by University Of Massachusetts Medical School lead by Dr Sean P Ryder, a Professor Biochemistry and Molecular Pharmacology has demonstrated that there are numerous emerging genomic variants of the SARS-CoV-2 coronavirus and that some of these with changes on certain of parts of the structure of the genome, he warns could lead to drug resistance.
Dr Ryder ...
COVID-19: Medical researchers and respiratory experts from the University of São Paulo's Medical School say that blood clotting disorders may explain some of the worst symptoms of COVID-19, including respiratory failure and pulmonary fibrosis and that the focus should be on treating COVID-19 as a thrombotic disease caused by a virus.
Their research findings and reports were published...
COVID-19 Drugs: Spanish researchers from the Rovira i Virgili University Department of Cheminformatics and Nutrition have identified that the anti-inflammatory drugs carprofen and celecoxib could have antiviral properties against the SARS-CoV-2 coronavirus that causes the deadly COVID-19 disease, by inhibiting replication of the virus.
The research study has been published by the Int...
COVID-19 Research: Medical researchers from Boston Children's Hospital have discovered that disulfiram, a US FDA-approved drug commonly used for treating alcoholism, blocks a key gatekeeper protein involved in inflammation, hence effectively inhibiting the inflammation process.
Typically, inflammation is the alarm system by which cells first respond to potential danger. But in e...
Source: COVID-19 Treatments May 24, 2020 7 days ago
COVID-19 Treatment: To date there are still no proven effective drugs or antivirals to treat COVID-19 or some of its accompanying symptoms such as the cytokine storms, blood clotting issues and the damage to epithelial cells etc.
sweet wormwood or Artemisia annua.
The public and medical community has been flooded with lots of misinformation that has been orchestrated by governments a...
COVID-19 Drugs: According to medical researchers from Johns Hopkins Kimmel Cancer Center, the high blood pressure drug Prazosin if given early enough, could potentially reduce the risk of death from the cytokine storms that arise as a complication of COVID-19 disease.
The blood pressure drug Prazosin, is an US FDA a U.S. Food-approved alpha blocker that relaxes blood vessels, a...
Source: COVID-19 Supplements May 13, 2020 18 days ago
COVID-19 Supplements: Medical researchers from the Harvard Medical School, University of California-Davis, Virginia Commonwealth University and Institute for Systems Biology, Seattle have discovered that chemical molecules called resolvins which are a type of novel endogenous specialized pro-resolving lipid autacoid mediators (SPMs) could help prevent the cytokine storms caused by the COVID-...
Source: COVID-10 Therapeutics May 11, 2020 20 days ago
COVID-19 Therapeutics: In many drug repurposing and potential therapeutics studies, researchers first use computational screening platforms that involves models of the SARS-CoV-2 coronavirus in detail especially the binding sites of the spike proteins and to match molecular models of existing drugs, supplements, phytochemicals etc to see which have a greater affinity to bind to these sites, ...
COVID-19 Drugs: A research study by Columbia University, Northwell Health and Massachusetts General Hospital shows that Famotidine, a common heartburn drug improved the clinical outcomes of hospitalized COVID-19 patients.
The study involving 1620 patients from more than 10 hospitals in the United States showed that Famotidine associated with reduced risk of intubation or death in hospitaliz...
COVID-19 Supplements: There are many who have always skeptical of the benefits of dietary supplements and nutraceuticals. While there has been many over blown claims by the unscrupulous, there are also many medical benefits that are often not extolled because of intense lobbying by the big pharmaceutical companies that have government and health authorities in their pockets along with greedy and u...
Source: COVID-19 Research May 04, 2020 27 days ago
COVID-19 Research: Glycosaminoglycans are a class of polydisperse and heterogeneous natural occurring products currently used as pharmaceuticals and even in nutritional supplements.
Included among them are unfractionated heparin, low molecular weight heparins, and heparinoids, all of which are clinically approved as anticoagulants with excellent bioavailability, stability, and safety pharmacokin...
COVID-19 Drugs: A study released by medical and drug researchers from the Laboratory of Vector-Borne Viral Diseases and Center for Biologics Evaluation, U.S. Food and Drug Administration, Maryland, has concluded that most of the antivirals used as experimental drugs in the last four months basically had no effect on treating COVID-19. https://www.biorxiv.org/content/10.1101/2020.04.29.067983...
COVID-19 Drugs: The US FDA finally on Friday warned doctors against prescribing a malaria drug touted by President Donald Trump for treating COVID-19.
A medical alert sent by the regulators flagged reports of sometimes fatal heart side effects among coronavirus patients taking hydroxychloroquine or the related drug chloroquine. The decades-old drugs, also prescribed fo...
COVID-19 Drugs: Media reports are emerging everywhere that not only has Gilead’s Remidesivir Clinical Trial in China failed but also there could be the possibility of a cover-up and future data being manipulated as a result of the Giant Pharma company’s extensive financial resources.
Reports are emerging that the experimental antiviral drug Remdesivir has failed in its first r...
Source: COVID-19 Drug Research Apr 21, 2020 1 month ago
COVID-19 Drug Research: A recent randomized, controlled study on the safety and efficacy of either lopinavir/ritonavir (LPV/r) or Arbidol, both antivirals that are used in some countries against HIV-1 and to treat influenza and respectively as treatments for COVID-19, the disease caused by the novel coronavirus SARS-CoV-2, suggests that neither drug improves the clinical outcome of patients hospit...
COVID-19 Drugs: Favipiravir or Avigan the flu drug that was developed by Toyama Chemicals in Japan that has since been acquired by Fuji Films Pharmaceuticals has been touted by many countries as an experimental drug for treating COVID-19 despite weak studies supporting its efficacy.
It was brought to media attention by China advocating its use in one of its national health guidelines based on r...
Source: COVID-19 Drug Research Apr 19, 2020 1 month ago
COVID-19 Drug Research: A new meta-analysis collaborative study by medical researchers from the University of San Diego and Yantai Yuhuangding Hospital in Shandong and also Shengjing Hospital in Shenyang, both in China, has confirmed that both Chloroquine and Hydroxychloroquine are both not effective for treating the COVID-19 disease and in fact caused a variety of adverse events in most pat...
COVID-19 Drugs: According to sources, a French research entity is planning to start a clinical trial on Ivermectin to treat COVID-19 disease soon.
A lot of medical professionals are now coming out in support of using Ivermectin as a experimental drug while the many clinical trials are underway may pave the path for its official repurposing as a COVID-19 drug.
The interest sta...
COVID-19 Drugs: An abstract study submitted by researchers from University Of Utah, Harvard Medical School and Surgisphere Corporation showed that COVID-19 patients who were critically ill with lung injury needing mechanical ventilation, benefitted from taking Ivermectin compared to other drug alternatives. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3570270
The study lead by Dr A...
COVID-19 Drugs: Ivermectin is gaining more attention as a possible drug candidate as it is an already approved drug for the treatment of parasites and also various virus causing diseases. It has already demonstrated to possess relevant antiviral properties.
More than 2.5 billion doses of the drugs have been used by humans in the last 30 years to treat malaria, dengue fever and even the &n...
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