COVID-19 Drugs - Acyclovir May 09, 2023 28 days ago
COVID-19 Drugs: Drug repurposing has garnered significant interest as a viable alternative to traditional drug development, offering a cost-effective, time-saving, and less risky approach. Amid the ongoing COVID-19 pandemic, the urgent need for therapeutic agents to prevent viral outbreaks has intensified.
Well-established antiviral drugs like acyclovir (Acv) have shown promise in combati...
COVID-19 Drugs - Drug Metabolizing Enzymes And Membrane Transporters (DMETs) May 01, 2023 1 month ago
COVID-19 Drugs: It is coming to light that all strategies with regards to treating COVID-19 has been wrong as many missed out certain critical data that affects the pharmacokinetics and pharmacodynamics of these drugs that have been approved so far by various clueless regulatory agencies across the world.
A new breakthrough study by researchers from University of Toronto-Canada, OneDrug-C...
COVID-19 Drugs: A groundbreaking study by Spanish researchers from Servicio de Salud de Castilla-La Mancha (SESCAM) in Toledo, Spain, has unveiled the astonishing potential of antihistamines as an early treatment for COVID-19. This discovery could revolutionize our approach to managing the pandemic, reduce hospitalizations, and possibly prevent the spread of the virus among close contacts.
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COVID-19 News: As the world continues to grapple with the COVID-19 pandemic, a natural amino acid, 5-aminolevulinic acid (ALA), is emerging as a potential antiviral for SARS-CoV-2 infections. This groundbreaking discovery could pave the way for an innovative treatment strategy that targets the angiotensin-converting enzyme 2 (ACE2) receptor, which plays a critical role in the virus's ability t...
COVID-19 Drugs: Since the outbreak of the COVID-19 pandemic, the scientific community has been tirelessly working to find effective therapeutic strategies to treat SARS-CoV-2-induced respiratory disease. Repurposing approved drugs has emerged as the most rapid, affordable, and efficient strategy for addressing this urgent need. Among the drugs tested for repurposing, methotrexate (MTX), a widely u...
COVID-19 News - Spike Protein Accumulating In Skull Marrow, Brain Meninges And Brain Parenchyma Apr 06, 2023 2 months ago
COVID-19 News: A new study by German and Danish researchers have found the SARS-Cov-2 spike protein accumulating in skull marrow, brain meninges and brain parenchyma while killing brain cells of those who had been exposed to the spike proteins either by infection or by so called mRNA ‘prophylactics.’
The SARS-CoV-2 virus, responsible for the COVID-19 pandemic, has been associa...
COVID-19 News: In an astounding revelation, a groundbreaking study by researchers from the Polish Academy of Sciences and A. Baitursynov Kostanay Regional University in Kazakhstan has identified a potential game-changer in the battle against the relentless SARS-CoV-2 Omicron variant.
Although the research is still in its preliminary, in silico phase, the astonishing findings are impossibl...
COVID-19 News : Resistance To Clinical Protease Inhibitors Mar 30, 2023 2 months ago
COVID-19 News: Research led by scientist from the University of Minnesota-USA has found that the SARS-CoV-2 coronavirus is evolving to escape all known clinical protease inhibitors. As drug resistance becomes a major issue in the coming CVID-19 onslaughts, a strategy of using a combination of antivirals like that in HIV treatment protocols might be a better solution.
The study also compri...
COVID-19 Drugs - Tucaresol Mar 23, 2023 2 months ago
COVID-19 Drugs: Tucaresol, an is an orally administered antisickling agent which increases the oxygen affinity of hemoglobin is emerging as a potential COVID-19 antiviral and drug to treat SARS-CoV-2 induced lymphopenia and immunodeficiency according to researchers from ChemThera Sciences, a pharmaceutical research company based in Montreal, Canada with a branch in Delaware, United States.
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COVID-19 Drugs - Chlorpromazine And Prochlorperazine Mar 21, 2023 3 months ago
COVID-19 Drugs: Indian researchers after conducting successful animal model drug trials involving hamsters are suggesting that G4-binding drugs, chlorpromazine and prochlorperazine could be repurposed against SARS-CoV-2 infections.
Chlorpromazine, marketed under the brand names Thorazine and Largactil among others, is an antipsychotic oral medication. It is primarily used to treat psychot...
COVID-19 Drugs - Beta-Amido Boronic Acids Mar 12, 2023 3 months ago
COVID-19 Drugs: The COVID-19 pandemic has been a global health crisis unlike any other in recent memory. It has affected millions of people around the world, and finding a cure has become a top priority for researchers and medical professionals. While vaccines have been developed and distributed, there is still a need for effective treatments for those who have already contracted the virus..hence ...
COVID-19 Drugs - Indomethacin Mar 11, 2023 3 months ago
COVID-19 Drugs: Since the beginning of the COVID-19 pandemic, researchers have been exploring various treatment options to combat the virus. One such option is the use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as indomethacin. While the use of NSAIDs in COVID-19 treatment remains a topic of debate, several studies have suggested that indomethacin, in particular, could be an effective t...
Long COVID News - Maraviroc - Pravastatin Mar 11, 2023 3 months ago
Long COVID News: A study by American and Costa Rican researchers has found that the drugs Maraviroc and Pravastatin can be used to treat Long COVID.
Maraviroc, sold under the brand names Selzentry and Celsentri, is an antiretroviral medication used to treat HIV infection. It is taken by mouth. It is in the CCR5 receptor antagonist class. It was approved for medical use in the United State...
Long COVID News - Metformin Prevents Long COVID Mar 10, 2023 3 months ago
Long COVID News: In a recent study, researchers from the University of Minnesota-USA investigated the potential benefits of early outpatient treatment of COVID-19 patients with metformin, ivermectin, or fluvoxamine in preventing the development of Long COVID, also known as post-acute sequelae of COVID-19 (PASC).
Their study findings showed that early use of metformin during initial SAR-Co...
COVID-19 News - Untreated COVID-19 Feb 22, 2023 3 months ago
COVID-19 News: A new study conducted by researchers from Brigham and Women's Hospital, Harvard Medical School,Massachusetts-USA and Harvard T.H. Chan School of Public Health-Massachusetts-USA involving a randomized clinical trial has surprisingly found that untreated COVID-19 infected individuals tend to fair better than those treated with Paxlovid (nirmatrelvir–ritonavir) in terms...
COVID-19 News - Gemfibrozil & Lovastatin, Reduces SARS-CoV-2 Neuroinfection Feb 13, 2023 4 months ago
COVID-19 News: A new study by South Korean researchers from Chonnam National University, Korea Research Institute of Chemical Technology along with scientist from University of North Carolina at Chapel Hill-USA has found that SARS-CoV-2 neuroinvasiveness and neuroinfection is governed by cholesterol homeostasis and translational machinery-associated genes! The study team found that brain corticoge...
COVID-19 News -China-Anti-SARS-CoV-2 Drugs - Xiannuoxin - VV116 Feb 08, 2023 4 months ago
COVID-19 News: The Chinese Academy of Sciences at Beijing has announced that China's National Medical Products Administration (NMPA) has conditionally approved tow new drugs to treat COVID-19 after an urgent review and approval under the Special Examination and Approval of Drugs Policy.
These two new novel antivirals are reported to be effective anti-SARS-CoV-2 drugs are Xiannuoxin (s...
COVID-19 News- Ciclesonide - Nsp3 - Nsp4 Mutations Feb 01, 2023 4 months ago
COVID-19 News: Researchers from the Research Center for Influenza and Respiratory Viruses, National Institute of Infectious Diseases, Murayama Branch, Tokyo-Japan have in a new study discovered that the usage of the inhaled asthma drug ciclesonide is causing frequent occurrences of SARS-CoV-2 NSp3 And Nsp4 Mutations!
Thailand Medical News had in our previous COVID-19 News coverages s...
COVID-19 Drugs - Fluvoxamine Causes Heart Valve Disease Jan 28, 2023 4 months ago
COVID-19 Drugs: Researchers from Columbia University’s Department of Surgery in collaboration with the Pediatric Heart Valve Center at Children’s Hospital of Philadelphia (CHOP), the University of Pennsylvania, and the Valley Hospital Heart Institute have discovered that serotonin can impact the mitral valve of the heart and potentially accelerate a cardiac condition known as degenerat...
COVID-19 Drugs - N-Acetylcysteine or NAC Jan 12, 2023 5 months ago
COVID-19 Drugs: A new study by Italian researchers have found that NAC or N-Acetylcysteine is not only an effective antiviral agent against all of the SARS-CoV-2 variants but also has immunomodulatory properties that can help prevent disease severity.
Thailand Medical News had as early as April 2020 written about the benefits of taking NAC or N-Acetylcysteine supplements to help prevent C...
COVID-19 Drugs - Molnupiravir Dec 24, 2022 5 months ago
COVID-19 Drugs: A new study led by researchers from University of Oxford has found that Molnupiravir that is being promoted by many charlatans and dubious health experts and authorities, does not reduce hospitalization or risk of mortality in vaccinated adults who have contracted COVID-19!
In fact, the overpriced drug that costs more than US$720 for a seven-day course day course has been ...
COVID-19 News - Chlorpromazine Dec 17, 2022 6 months ago
COVID-19 News: A new study by researchers from Inserm (French National Institute of Health and Medical Research) has validated that cholesterol and ceramide lipids facilitate SARS-CoV-2 spike protein-mediated membrane fusion.
The researchers also found that Chlorpromazine (CPZ), a commonly used antipsychotic drug, could be used to inhibit this fusion and also prevent SARS-CoV-2 cellular e...
COVID-19 Drugs - Ursodeoxycholic Acid Dec 15, 2022 6 months ago
COVID-19 Drugs: A new breakthrough study led by researchers from Cambridge University-UK has found that the commonly available cheap generic drug used to treat a type of liver disease ie Ursodeoxycholic Acid (UDCA), could be repurposed to not only treat COVID-19 but also act as an effective prophylactic.
The drug is also not only effective against all existing SARS-CoV-2 variants but also...
Source: COVID-19 Drugs - Diabetics - SGLT-2 Inhibitors Dec 08, 2022 6 months ago
COVID-19 Drugs: A new study by researchers from Fujian Medical University -China, Fujian Provincial Hospital-China and Fujian Academy of Medical Sciences-China has found that diabetics taking SGLT-2i drugs like canagliflozin, dapagliflozin, and empagliflozin prior to contracting COVID-19 have reduced adverse outcomes.
SGLT2i or sodium-glucose cotransporter-2 inhibitors are a class of prescription...
COVID-19 News - Bebtelovimab Dec 01, 2022 6 months ago
COVID-19 News: The U.S. FDA issued an announcement in the last 24 hours stating that Bebtelovimab is not currently authorized in any U.S. region to treat COVID-19.
According to the announcement, the predominant variants in circulation that includes the BQ.1 and BQ.1.1 variants ad sub-lineages can no longer be neutralized by the monoclonal antibody drug Bebtelovimab that is made by ph...
COVID-19 News - Molnupiravir Nov 30, 2022 6 months ago
COVID-19 News: When Thailand Medical News in September 2021 warned about the dangers of the US FDA approved drug Molnupiravir to treat COVID-19, our news coverage was not taken seriously as most Westerners always think that only the media in their own countries that is funded by crooked politicians, unethical billionaires, greedy pharma giants and those controlling the COVID-19 narratives are the ...
COVID-19 News - Interferon Lambda Nov 19, 2022 7 months ago
COVID-19 News: A new breakthrough study by Canadian researchers from the University of Manitoba, University of Toronto, Canada University Health Network and University of Alberta, Edmonton has found that treating SARS-CoV-2 infected individuals with interferon Lambda helps in rapid clearance of the virus even in those with age-related delays in the induction of T cell immunity!
This new t...
Source: COVID-19 News - Inhalable Sodium Bicarbonate As An Adjuvant For COVID-19 Nov 19, 2022 7 months ago
COVID-19 News: A randomized clinical trial conducted by researchers from the Faculty of Medicine, Mansoura University - Egypt has found that inhalable sodium bicarbonate could be used as adjuvant in COVID-19 prophylactic and treatment protocols!
Most COVID-19 News outlets have not been covering on the various clinical trials involving cheaper repurposed drugs or compounds that can be used...
Source: COVID-19 Drugs - Metformin Nov 18, 2022 7 months ago
COVID-19 Drugs: Study findings from yet another research led by scientists from the University of Minnesota Medical School has added to the growing evidence that metformin, a common and cheap generic diabetic drug is able to decrease the risk of COVID-19 severity.
Thailand Medical News had previously covered on various past studies that showed metformin not only reduced the risk of COVID-...
Source: COVID-19 News - Cyclodextrins - SARS-CoV-2 - Antivirals Nov 17, 2022 7 months ago
COVID-19 News: A new study by researchers from Spain led by scientist from the Cell Structure Lab, Centro Nacional de Biotecnologia, CNB - CSIC, Campus de Cantoblanco, Madrid -Spain has found that cheap natural cyclodextrins especially Beta Cyclodextrins can be used as antivirals against SARS-CoV-2!
Cyclodextrins are a family of cyclic oligosaccharides, consisting of a macrocyclic ring of...
Source: COVID-19 Drugs - Fluvoxamine Nov 07, 2022 7 months ago
COVID-19 Drugs: A new study by researchers from Intermountain Medical Center; Stanford, Salt Lake City-Utah, USA has confirmed that the usage of selective serotonin reuptake inhibitors (SSRIs) such as Fluoxetine or Fluvoxamine does not reduce COVID Severity.
Shockingly, the study findings showed that hospitalization and death were significantly greater in the those taking SSRIs such as Fluoxetine...
Source: COVID-19 Drugs - Memantine - NMT5 Nov 02, 2022 7 months ago
COVID-19 Drugs: Researchers from Scripps Research Institute - California-USA have created a variant of the generic drug Memantine which is an Aminoadamantane compound, to inhibit the SARS-CoV-2 virus entry by targeting the ACE2 receptors.
Prevention of infection and propagation of the SARS-CoV-2 coronavirus is a high priority in the ongoing COVID-19 pandemic which is expected to get worse...
Source; COVID-19 Drugs -Inhaled Ciclesonide Oct 30, 2022 7 months ago
COVID-19 Drugs: A new study by researchers from the Division of Pulmonary and Critical Care Medicine at MacKay Memorial Hospital- Taiwan has found that the usage of inhaled Ciclesonide reduces risk of mortality and need for mechanical ventilation in hospitalized COVID-19 patients.
Thailand Medical News had already reported as early as August 2020 about the possible prophylactic and also t...
Source: COVID-19 News - Banana Lectin H84T As A SARS-CoV-2 Antiviral Oct 21, 2022 8 months ago
COVID-19 News: A new study conducted by researchers from University of Hong Kong – China, Johannes Kepler University Linz, Linz – Austria and the University of Michigan, Ann Arbor-USA has found that lectins derived from bananas could serve as effective antivirals against the SARS-CoV-2 virus including against the Omicron variant.
As early as 2020, Thailand Medical News has cov...
Source: COVID-19 Drugs - Paxlovid Oct 13, 2022 8 months ago
COVID-19 Drugs: Leading cardiologists and physicians from various hospitals and medical centers across the state of Massachusetts-USA have issued a warning of adverse drug interactions especially involving heart medications in COVID-19 patients treated with Paxlovid (Nirmatrelvir/Ritonavir).
The team of specialists from Lahey Hospital and Medical Center, Brigham and Women’s Hospital...
Source: COVID-19 Drugs -Glutamine, Pyruvate, Rosiglitazone, Arginine, 2-DG Oct 11, 2022 8 months ago
COVID-19 Drugs: A new breakthrough study by researchers from the Zhongnan Hospital of Wuhan University-China and Southern University of Science and Technology, Shenzhen-China has found that glutamine and pyruvate supplementation, and also the drug diabetic drug Rosiglitazone can reduce and prevent cytokine upregulation hyperinflammation as result of inflammation in macrophages induced by the SARS-...
Source: COVID-19 Drugs - Metformin Oct 11, 2022 8 months ago
COVID-19 Drugs: Spanish researchers and physicians have in a new study found that the diabetic drug Metformin (Glucophage) lowers the risk of disease severity and fatal outcomes in diabetic patients infected with the SARS-CoV-2 coronavirus.
The study involved medical researchers from the Hospital Clinic of Barcelona-Spain, Universitat Autònoma de Barcelona-Spain and Fundació Institu...
Source: COVID-19 Drugs - Evusheld - Bebtelovimab Oct 04, 2022 8 months ago
COVID-19 Drugs: Thailand Medical News has been warning since the last two weeks that we are entering a very dangerous phase of the COVID-19 pandemic, one in which not only are we are going to be faced with an onslaught of more than 30 to 50 circulating new Omicron sub-lineages that are more transmissible and immune evasive but also more pathogenic. Reinfections and Co-infections are going to be th...
Source: Medical News - Povidone Nasal Sprays For COVID-19 Aug 24, 2022 10 months ago
A study by researchers from Mahidol University, Siam University and Samut Sakhon Hospital has found that 0.4% povidone-iodine nasal spray is not the least effective as a prophylaxis to prevent SARS-CoV-2 infections.
During the initial phases of the SARS-CoV-2 pandemic, numerous Indian scammers and Indian run companies were promoting various Povidone-iodine nasal sprays products as prophyl...
Source: Medical News - COVID-19 Drugs - Metformin Aug 22, 2022 10 months ago
COVID-19 Drugs: A randomized clinical trial involving 1431 non-hospitalized patients showed that metformin reduced the risk of COVID-19 severity and risk of COVID-19 mortality.
The randomized double-blinded placebo- controlled trial by conducted by the COVID-OUT consortium that is led by researchers from University of Minnesota and also involved medical scientists from the UnitedHealth Gro...
Source: Medical News - COVID-19 Drugs -Remdesivir Aug 13, 2022 10 months ago
COVID-19 Drugs: A new study by Japanese researchers from Tohoku University, Kyushu University, Okayama University and the National Institutes of Natural Sciences, Okazaki-Japan has alarmingly found that the U.S. FDA approved and heavily promoted drug for COVID-19 ie Remdesivir activates the urotensin II receptor and induces cardiomyocyte dysfunction that can lead to heart issues that can also end ...
COVID-19 Drugs: The World Health Organization has strongly advised against the usage of two drugs to treat non-severe COVID-19, ie the antidepressant drug fluvoxamine and the gout drug colchicine.
The WHO said that both drugs were not recommended for patients with mild or moderate COVID-19 because there is currently insufficient evidence that they improve important outcomes for patients, and both...
COVID-19 Drugs: A new study by medical researchers from Stanford University-California has found that the commonly available and cheap generic drug, Spironolactone (Aldactone) improves clinical outcomes especially in severe COVID-19 infections.
Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liv...
Source: COVID-19 Drugs-Paxlovid Jun 16, 2022 12 months ago
In a surprising move, the American big pharma company that is a major supporter of the Biden administration…Pfizer Inc on Tuesday announced that it would halt enrollment in a clinical trial for its claimed COVID-19 antiviral COVID-19 drug-Paxlovid, in standard-risk patients after data analysis showed a non-significant reduction in hospitalizations and deaths.
Typically, the standar...
Source: COVID-19 Drugs - Nirmatrelvir & Paxlovid Jun 10, 2022 1 year ago
COVID-19 Drugs: A new study by researchers from the Copenhagen University Hospital-Denmark, the Department of Immunology and Microbiology at the University of Copenhagen-Denmark and the Technical University of Denmark has found that the mutations E166V and L50F+E166V that are found on various emerging SARS-CoV-2 variants, weakens nirmatrelvir-Mpro binding. Nirmatrelvir, an oral protease inhibitor ...
Source: COVID-19 Drugs - Clofoctol May 30, 2022 1 year ago
COVID-19 Drugs: A new study by researchers from the University of Lille-France, the Institut Pasteur de Lille-France, the Center for Infection and Immunity of Lille-France, CNRS, INSERM, and CHU Lille0France has found that the existing antibiotic Clofoctol could be repurposed to treat COVID-19.
Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nos...
Source: COVID-19 Drugs - Viagra - Sildenafil May 18, 2022 1 year ago
COVID-19 Drugs: A new study by researchers from the University College London-UK, Imperial College London and the Royal Brompton Hospital-UK has found that the drug Viagra can be used to treat COVID-19 related pneumonitis and moderate to severe ARDS.
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hyperte...
Source: COVID-19 Drugs - Montelukast Apr 28, 2022 1 year ago
COVID-19 Drugs: Researchers from the Indian Institute of Science, India has found that the asthma drug Montelukast (Singulair) can block the SARS-CoV-2 non-structural protein 1 (Nsp1,) which in turn results in the inhibition of SARS-CoV-2 replication, showing it prowess as potential COVID-19 drug!
Montelukast is a drug used in the maintenance treatment of asthma that is marketed under the trade n...
Source: SARS-CoV-2-Minocycline Apr 23, 2022 1 year ago
SARS-CoV-2-Minocycline: News has emerged that China is now using the antibiotic drug Minocycline to treat COVID-19 cases in various cities across China including Shanghai despite lack of published clinical trial studies showing its efficacy.
Chinese researchers from the Chinese Academy of Medical Sciences & Peking Union Medical College along with scientists from the Inner Mongolia Medical Un...
Source: COVID-19 Drugs - Paxlovid Apr 20, 2022 1 year ago
We at Thailand Medical News think that urgent studies are needed by independent and credible researchers with regards to Pfizer’s Paxlovid as there are many now many unpublished case reports by both physicians and also patients reporting anomalies when the so-called antiviral drug is used to treat COVID-19 patients.
One common occurrence being reported is that many when tested posit...
Source: Medical News - NAC Apr 14, 2022 1 year ago
Yet another worrisome study finding has emerged that adds to the growing list of human host cellular and biological pathways… now numbering in hundreds, that are dysregulated or disrupted by the SARS-CoV-2 coronavirus with implications for long term medical and health issues, some that can end up with fatal outcomes.
Already Thailand Medical News has issued numerous warnings that m...
No this is not some April Day prank nor it is some fear porn to get everyone anxious, rather this is stark warning that everyone who has been exposed to the proteins of the SARS-CoV-2 virus through whichever means need to take it upon themselves to do frequent medical checkups and also to take necessary precautions and also to seek out treatment protocols to self-treat themselves as even the...
Source: COVID-19 Drugs - Aspirin Mar 25, 2022 1 year ago
COVID-19 Drugs: A new cohort study by researchers from George Washington University-USA has demonstrated that aspirin use is associated with reduced risk of mortality in hospitalized moderate COVID-19 patients.
Previous observational studies already showed that aspirin use may be associated with reduced mortality in high-risk hospitalized patients with COVID-19, but aspirin’s effica...
Source: COVID-19 Drugs - Famotidine Mar 02, 2022 1 year ago
COVID-19 Drugs: The study findings of a phase 2 clinical trial led by Feinstein Institutes for Medical Research-New York and Cold Spring Harbor Laboratory shows that the common heart burn drug Famotidine is effective in treating COVID-19 disease especially for those with in mild to moderate cases.
It should be noted that Thailand Medical News first reported on the potential of using famot...
Pharma News: Fake molnupiravir pills under a variety of brandnames are appearing not only on various illegal online sites that are selling controlled medications but also in many pharmacies around the world that are known to also sell controlled drugs illegally and also in the various notorious drug ‘black-market retail sites’.
It was reported that only after a week in January when mo...
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