Source: COVID-19 Research May 08, 2021 1 month ago
New Emerging T205I And D399N Mutations On Various Strains Of New Variants Evade Detection By Most Current COVID-19 PCR Tests
Researchers from University of Washington and the Fred Hutchinson Cancer Research Center-Seattle, have in a new study found that there are emerging mutations such as T205I And D399N present in the nucleocapsid protein of new variants are helping the SARS-C...
Source: COVID-19 Diagnostics Jan 10, 2021 5 months ago
COVID-19 Diagnostics: The US FDA has issued official warnings about the potential risk for false negative results with PCR molecular tests for SARS-CoV-2 due to mutations such as a recently detected B.1.1.7 variant of the virus.
The US regulator issued an alert to clinical laboratory staff and clinicians. The agency warned that false negative results can occur with any molecular test for ...
Source: COVID-19 Diagnostics Dec 06, 2020 6 months ago
COVID-19 Diagnostics: Researchers from Gladstone Institutes, University of California, Berkeley (UC Berkeley), and University of California, San Francisco (UCSF) have developed a new fast and portable yet accurate COVID-19 diagnostic platform utilizing CRISPR testing technology and the smartphone camera.
The SARS-CoV-2 coronavirus outbreak has become an ongoing global pandemic due in part...
Source: COVID-19 Diagnostics Oct 21, 2020 8 months ago
COVID-19 Diagnostics: Siemens Healthineers has introduced the CLINITEST Rapid COVID-19 Antigen Test that helps identify SARS-CoV-2 infected individuals in 15 minutes so they can isolate sooner and avoid spreading COVID-19.
The easy-to-use test, which doesn't require specialized laboratory personnel or instruments, offers flexibility to test in locations that benefit from immediate results
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Source: COVID-19 Diagnostics Oct 14, 2020 8 months ago
COVID-19 Diagnostics: A new study led by resarchesr from University of Michigan and involved an internation collaboration of various scientist and medical institutions from various countries has identified a protein called suPAR or soluble urokinase plasminogen activator receptor that can be used as a biomarker in blood diagnostics to identify COVID-19 patients who at risk of AKI or acut...
COVID-19 Test: A large multidisciplinary group of researchers from University of California-San Francisco, J. David Gladstone Institutes-San Francisco, University of California-Berkeley, Monash University-Australia and Chan Zuckerberg Biohub-San Francisco have developed an amplification-free CRISPR-based mobile phone assay for direct detection of the severe acute respiratory syndrome coronav...
Source: COVID-19 Testing Oct 03, 2020 9 months ago
COVID-19 Testing: Researchers from University of Vermont, working in collaboration with a group from the University of Washington, have developed a platform of testing for the COVID-19 disease that does not make use of key chemicals, or reagents but still delivers an accurate result, paving the way for inexpensive, widely available testing in both developing countries and industrialized nations li...
Source: COVID-19 Diagnostics Sep 28, 2020 9 months ago
COVID-19 Diagnostics: Researchers from Duke University Medical Center-North Carolina have identified biomarkers that accurately identify numerous viral infections across the clinical stages of disease, advancing a potential new way to guide treatment, quarantine decisions, and other clinical and public health interventions in the setting of endemic and pandemic infectious diseases.
The un...
Source: COVID-19 Diagnostics Sep 25, 2020 9 months ago
COVID-19 Diagnostics: Immunology experts at the University of Birmingham-UK have developed a new COVID-19 test using dried blood spot samples (DBS) as an accurate alternative to venous blood in detecting SARS-CoV-2 antibodies.
DBS sampling is simple, inexpensive and can be self-collected by
the patient at home, using a simple finger prick.
Credit: University Of Birmingham
The research fin...
Source: COVID-19 Research Sep 10, 2020 9 months ago
A new COVID-19 Research by scientist from Murdoch University-Australia led by Professor Dr Jeremy K. Nicholson and Professor Dr Elaine Holmes have discovered that by comparing lipoproteins and metabolites in the blood of COVID-19 patients and healthy subjects, not only are signs of multi-organ damage apparent but a distinct metabolite signature was observed in COVID-19 patients that could be furth...
COVID-19 Alerts: According to a new UK study by Universities of Warwick and Birmingham, home-testing kits sold online in the UK, US and elsewhere in the midst of the COVID-19 crisis were provided with incomplete and in most cases, misleading information on how accurate they were.
Worst till there were reports from other regulatory bodies, medical institutions and consumer boards that some...
COVID-19-Gut: A new study by researchers from the Chinese University of Hong Kong has found that the SARS-CoV-2 coronavirus may continue to infect and replicate in the digestive tract after clearing in the airways. https://www.cpr.cuhk.edu.hk/en/press_detail.php?id=3356
It was also observed that COVID-19 patients have active and prolonged gut viral infection, even in the absence of gastro...
Source: Diagnostics-COVID-19 Sep 08, 2020 9 months ago
Diagnostics-COVID-19: UK based biotech firm Avacta Group plc ,the developer of Affimer® biotherapeutics and reagents has announced the launch of an ultra-sensitive ELISA laboratory test for the SARS-CoV-2 spike protein to support global research efforts into the SARS-CoV-2 coronavirus that causes COVID-19.
Dr Alastair Smith, Avacta’s chief executive
ELISAS or enzyme l...
Source: COVID-19 Diagnostics Sep 08, 2020 9 months ago
COVID-19 Diagnostics: Researchers from Icahn School of Medicine-Mount Sinai in a new study have found that D-Dimers, a fragment protein produced by the breakup of fibrin clots can be used as a biomarker to determine which patients are at the risk of dying.
Information such as this which predicts a COVID-19 patient’s risk of mortality is useful in designing clinical treatment protoco...
Source: COVID-19 Diagnostics Aug 29, 2020 10 months ago
COVID-19 Diagnostics: Genomic and biotech researchers from the Chan Zuckerberg Biohub-San Francisco, and collaborators have warned against only targeting one viral gene when carrying out reverse transcriptase-polymerase chain reaction (RT-PCR) testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
The study team conducted a study showing that a mutation had arisen in th...
Source: COVID-19 Antigen Test Aug 27, 2020 10 months ago
COVID-19 Antigen Test: The US FDA today announced that it has issued an emergency use authorization for the first antigen test where results can be read directly from the testing card, a similar design to some pregnancy tests.
This easy use but simple design test kits are fast and efficient for healthcare providers and patients and does not need the use of an analyzer.
Dr Jeff Shur...
Source: U.S. Medical News Aug 22, 2020 10 months ago
U.S. Medical News: In what is shocking the medical community not only in America but also internationally, the white house has issued a new policy order midweek that removed all regulatory powers from the US FDA with regards to regulating and standardizing all medical laboratory test.
The new order which even stunned the US FDA, shocked health experts and laboratories because of its timin...
Source: COVID-19 Biomarkers Aug 10, 2020 10 months ago
COVID-19 Biomarkers: Medical and immunology researchers from the Ragon Institute of Massachusetts General Hospital, MIT and Harvard Medical School, and the University of Washington School of Medicine, have identified immune response markers that, collectively, were able to distinguish between those COVID-19 patients who convalesced from the infection, and those who did not survive the disease.
&...
Source: COVID-19 Clinical Care Aug 07, 2020 10 months ago
COVID-19 Clinical Care: Medical researchers from George Washington University (GW) have identified five blood biomarkers that are associated with higher odds of clinical deterioration and death in COVID-19 patients.
The research findings were published in the journal Future Medicine, with the hope that these findings will help physicians better predict outcomes for COVID-19 patients ...
Source: COVID-19 Diagnostics Jul 25, 2020 11 months ago
COVID-19 Diagnostics: Korean researchers in a new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.
The researchers suggest that a...
Source: COVID-19 Diagnostics Jul 24, 2020 11 months ago
COVID-19 Diagnostics: Israeli biotech company, Nanoscent has developed a SARS-CoV-2 coronavirus breathalyzer test that gives results in less than 30 seconds, billing it as a "front line" tool that can help restore a sense of normality during the pandemic.
The breathalyser is not meant to replace lab tests, but is a mass screening tool
The company said an extensive trial in Israe...
Source: COVID-19 Diagnostics Jul 21, 2020 11 months ago
COVID-19 Diagnostics: According to newly published research from cardiologists at the University of Alberta, a new blood test that reliably predicts outcomes for heart failure patients could lead to new diagnostics and treatments for COVID-19 patients as well.
The medical researchers examined circulating angiotensin peptide levels in the blood of 110 people who were experiencing hear...
Source: COVID-19 Diagnostics Jul 18, 2020 11 months ago
COVID-19 Diagnostics: Roughly between 8 to 12% of individuals with COVID-19 disease progresses to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome.
Although these forms sometimes occur early in the course of the disease, clinical observations generally describe a two-stage progression of the disease, beginning ...
Source: COVID-19 Diagnostics Jul 17, 2020 11 months ago
COVID-19 Diagnostics: Researchers from Coney Island Hospital-New York in a new study have found that a simple rapid laboratory test, the eosinophil count, readily obtained from a routine complete blood cell count (CBC) can aid in the early recognition of COVID-19 in patients, as well as provide prognostic information.
Their research findings have been published in The Journal of the Ameri...
Source: COVID-19 Diagnostics Jul 09, 2020 11 months ago
COVID-19 Diagnostics: Researchers from the University of Exeter have developed a revolutionary new device that could allow health professionals to accurately test patients' antibody response to COVID-19 in as little as seven minutes.
The new pioneering COVID-19 Triple Antibody Test has been produced by the University of Exeter spin-out company Attomarker Ltd and is set to spearhead th...
Source: COVID-19 Diagnostics Jul 06, 2020 12 months ago
COVID-19 Diagnostics: A new research from the University of Virginia (UVA) School of Medicine suggests doctors can examine COVID-19 patients' blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a ventilator. The main biomarker that should be looked out for is the cytokine IL-13 (Interleukin 13). High levels of IL-13 were associated with worsened...
Source: COVID-19 Diagnostics Jul 05, 2020 12 months ago
COVID-19 Diagnostics: The US FDA last week on granted Emergency Use Authorization to a new molecular diagnostic test from the US Centers for Disease Control and Prevention that can detect and differentiate the viruses that cause COVID-19 and flu.
The new Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay is a real-time RT-PCR test intended for the simultaneous detection and differ...
Source: COVID-19 Diagnostics Jul 03, 2020 12 months ago
COVID-19 Diagnostics: Despite the fact that accurate and widespread testing is crucial to managing the coronavirus pandemic, many individuals in the U.S. and even elsewhere globally still can’t get tested for COVID-19 without visiting designated sites.
A rendering of a potential affordable, handheld COVID-19 testing device.
The researchers hope to be evaluating prototyp...
Source: COVID-19 Diagnostics Jul 02, 2020 12 months ago
COVID-19 Diagnostics: Researchers from the Innovative Genomics Institute (IGI), the same UC Berkeley group that rapidly popped up a state-of-the-art COVID-19 testing laboratory in March, are now trialing a quicker way to obtain patient samples: through saliva.
So far diagnostic tests for COVID-19 have relied on samples obtained by swabbing uncomfortably deep into a person’s nasal pa...
Source: COVID-19 Antibodies Jul 02, 2020 12 months ago
COVID-19 Antibodies: A new research published by the British Medical Journal, (BMJ) yesterday highlights major weaknesses that exist in the evidence base for COVID-19 antibody tests. https://www.bmj.com/content/370/bmj.m2516
The research found that the evidence is particularly weak for point-of-care tests (performed directly with a patient, outside of a laboratory) and does not support...
Source: Health Tech Startups Jun 30, 2020 12 months ago
Health Tech Startups: A team of National University Of Singapore (NUS) researchers have developed a portable COVID-19 micro-PCR diagnostic system called Epidax that enables rapid and accurate on-site screening of infectious diseases and significantly reduces the time required to analyze patient samples. With this new innovation COVID-19 screening can soon be conducted directly at various testing s...
Source: COVID-19 Antibody Test Jun 12, 2020 1 year ago
COVID-19 Antibody Test: Scientists and researchers from University Of North Carolina School Of Medicine have developed a new kind of antibody test that could be ramped up to test thousands of blood samples at labs that do not have the resources of commercial labs and large academic medical centers.
The team created a blood test to pinpoint SARS-CoV-2 antibodies that target one u...
Source: COVID-19 Diagnostics Jun 11, 2020 1 year ago
COVID-19 Diagnostics: As the SARS-CoV-2 has the potential to mutate, and numerous studies and genomic sequencings have already shown that many mutated strains of the SARS-CoV-2 has emerged, it is critically significant to check the efficacy of current diagnostic tests, warns York University researchers, who found seven out of 27 methods had potential sequence mismatch issues that may lead to under...
Source: COVID-19 Diagnostics Jun 03, 2020 1 year ago
COVID-19 Diagnostics: A team of medical and biotech researchers led by Dr Chaofeng Ma of Xi'an Center for Disease Control and Prevention in China had initially hypothesized that viral inactivation may contribute to false negatives.
The researchers subsequently tested several inactivation methodologies to determine if and to what extent they reduce detectible virus in a clinical s...
Source: COVID-19 Diagnostics May 27, 2020 1 year ago
COVID-19 Diagnostics: Medical researchers from John Hopkins based on new study findings are warning about the accuracy of current RT-PCR Diagnostic platforms being used globally to detect those infected with the SARS-CoV-2 coronavirus and also about false negatives.
The research findings were published in the journal Annals of Internal Medicine. https://www.acpjournals.org/doi/10.732...
Source: COVID-19 Diagnostics May 09, 2020 1 year ago
COVID-19 Diagnostics: Biotech Firm, Rutgers' RUCDR Infinite Biologics received an amended emergency use authorization from the US FDA for the first SARS-CoV-2 coronavirus/COVID-19 test that will allow individuals to collect their own saliva in the comfort of their homes and send to a lab for testing and results, without risking any exposure in crowded healthcare settings.
The ne...
Source: COVID-19 Diagnostics Apr 18, 2020 1 year ago
COVID-19 Diagnostics: To date, millions of individuals have been tested for the SARS-CoV-2 coronavirus, most using a kit that relies on the polymerase chain reaction (PCR). This sensitive method amplifies SARS-CoV-2 RNA from patient swabs using a thermocycler machine so that tiny amounts of the virus can be detected. But as the crisis surges, this laboratory technique that is time consum...
Source: COVID-19 Diagnostics Apr 17, 2020 1 year ago
COVID-19 Diagnostics: According to an open-access Clinical Perspective article in the American Journal of Roentgenology (AJR), so far the radiology literature on coronavirus disease (COVID-19) pneumonia has consisted of limited retrospective studies that do not substantiate the use of CT as a diagnostic test for COVID-19. https://www.ajronline.org/doi/10.2214/AJR.20.23202
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