Source: COVID-19 Biomarkers Aug 10, 2020 2 days ago
COVID-19 Biomarkers: Medical and immunology researchers from the Ragon Institute of Massachusetts General Hospital, MIT and Harvard Medical School, and the University of Washington School of Medicine, have identified immune response markers that, collectively, were able to distinguish between those COVID-19 patients who convalesced from the infection, and those who did not survive the disease.
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Source: COVID-19 Clinical Care Aug 07, 2020 5 days ago
COVID-19 Clinical Care: Medical researchers from George Washington University (GW) have identified five blood biomarkers that are associated with higher odds of clinical deterioration and death in COVID-19 patients.
The research findings were published in the journal Future Medicine, with the hope that these findings will help physicians better predict outcomes for COVID-19 patients ...
Source: COVID-19 Diagnostics Jul 25, 2020 18 days ago
COVID-19 Diagnostics: Korean researchers in a new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.
The researchers suggest that a...
Source: COVID-19 Diagnostics Jul 24, 2020 19 days ago
COVID-19 Diagnostics: Israeli biotech company, Nanoscent has developed a SARS-CoV-2 coronavirus breathalyzer test that gives results in less than 30 seconds, billing it as a "front line" tool that can help restore a sense of normality during the pandemic.
The breathalyser is not meant to replace lab tests, but is a mass screening tool
The company said an extensive trial in Israe...
Source: COVID-19 Diagnostics Jul 21, 2020 22 days ago
COVID-19 Diagnostics: According to newly published research from cardiologists at the University of Alberta, a new blood test that reliably predicts outcomes for heart failure patients could lead to new diagnostics and treatments for COVID-19 patients as well.
The medical researchers examined circulating angiotensin peptide levels in the blood of 110 people who were experiencing hear...
Source: COVID-19 Diagnostics Jul 18, 2020 25 days ago
COVID-19 Diagnostics: Roughly between 8 to 12% of individuals with COVID-19 disease progresses to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome.
Although these forms sometimes occur early in the course of the disease, clinical observations generally describe a two-stage progression of the disease, beginning ...
Source: COVID-19 Diagnostics Jul 17, 2020 26 days ago
COVID-19 Diagnostics: Researchers from Coney Island Hospital-New York in a new study have found that a simple rapid laboratory test, the eosinophil count, readily obtained from a routine complete blood cell count (CBC) can aid in the early recognition of COVID-19 in patients, as well as provide prognostic information.
Their research findings have been published in The Journal of the Ameri...
Source: COVID-19 Diagnostics Jul 09, 2020 1 month ago
COVID-19 Diagnostics: Researchers from the University of Exeter have developed a revolutionary new device that could allow health professionals to accurately test patients' antibody response to COVID-19 in as little as seven minutes.
The new pioneering COVID-19 Triple Antibody Test has been produced by the University of Exeter spin-out company Attomarker Ltd and is set to spearhead th...
Source: COVID-19 Diagnostics Jul 06, 2020 1 month ago
COVID-19 Diagnostics: A new research from the University of Virginia (UVA) School of Medicine suggests doctors can examine COVID-19 patients' blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a ventilator. The main biomarker that should be looked out for is the cytokine IL-13 (Interleukin 13). High levels of IL-13 were associated with worsened...
Source: COVID-19 Diagnostics Jul 05, 2020 1 month ago
COVID-19 Diagnostics: The US FDA last week on granted Emergency Use Authorization to a new molecular diagnostic test from the US Centers for Disease Control and Prevention that can detect and differentiate the viruses that cause COVID-19 and flu.
The new Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay is a real-time RT-PCR test intended for the simultaneous detection and differ...
Source: COVID-19 Diagnostics Jul 03, 2020 1 month ago
COVID-19 Diagnostics: Despite the fact that accurate and widespread testing is crucial to managing the coronavirus pandemic, many individuals in the U.S. and even elsewhere globally still can’t get tested for COVID-19 without visiting designated sites.
A rendering of a potential affordable, handheld COVID-19 testing device.
The researchers hope to be evaluating prototyp...
Source: COVID-19 Diagnostics Jul 02, 2020 1 month ago
COVID-19 Diagnostics: Researchers from the Innovative Genomics Institute (IGI), the same UC Berkeley group that rapidly popped up a state-of-the-art COVID-19 testing laboratory in March, are now trialing a quicker way to obtain patient samples: through saliva.
So far diagnostic tests for COVID-19 have relied on samples obtained by swabbing uncomfortably deep into a person’s nasal pa...
Source: COVID-19 Antibodies Jul 02, 2020 1 month ago
COVID-19 Antibodies: A new research published by the British Medical Journal, (BMJ) yesterday highlights major weaknesses that exist in the evidence base for COVID-19 antibody tests. https://www.bmj.com/content/370/bmj.m2516
The research found that the evidence is particularly weak for point-of-care tests (performed directly with a patient, outside of a laboratory) and does not support...
Source: Health Tech Startups Jun 30, 2020 1 month ago
Health Tech Startups: A team of National University Of Singapore (NUS) researchers have developed a portable COVID-19 micro-PCR diagnostic system called Epidax that enables rapid and accurate on-site screening of infectious diseases and significantly reduces the time required to analyze patient samples. With this new innovation COVID-19 screening can soon be conducted directly at various testing s...
Source: COVID-19 Antibody Test Jun 12, 2020 2 months ago
COVID-19 Antibody Test: Scientists and researchers from University Of North Carolina School Of Medicine have developed a new kind of antibody test that could be ramped up to test thousands of blood samples at labs that do not have the resources of commercial labs and large academic medical centers.
The team created a blood test to pinpoint SARS-CoV-2 antibodies that target one u...
Source: COVID-19 Diagnostics Jun 11, 2020 2 months ago
COVID-19 Diagnostics: As the SARS-CoV-2 has the potential to mutate, and numerous studies and genomic sequencings have already shown that many mutated strains of the SARS-CoV-2 has emerged, it is critically significant to check the efficacy of current diagnostic tests, warns York University researchers, who found seven out of 27 methods had potential sequence mismatch issues that may lead to under...
Source: COVID-19 Diagnostics Jun 03, 2020 2 months ago
COVID-19 Diagnostics: A team of medical and biotech researchers led by Dr Chaofeng Ma of Xi'an Center for Disease Control and Prevention in China had initially hypothesized that viral inactivation may contribute to false negatives.
The researchers subsequently tested several inactivation methodologies to determine if and to what extent they reduce detectible virus in a clinical s...
Source: COVID-19 Diagnostics May 27, 2020 3 months ago
COVID-19 Diagnostics: Medical researchers from John Hopkins based on new study findings are warning about the accuracy of current RT-PCR Diagnostic platforms being used globally to detect those infected with the SARS-CoV-2 coronavirus and also about false negatives.
The research findings were published in the journal Annals of Internal Medicine. https://www.acpjournals.org/doi/10.732...
Source: COVID-19 Diagnostics May 09, 2020 3 months ago
COVID-19 Diagnostics: Biotech Firm, Rutgers' RUCDR Infinite Biologics received an amended emergency use authorization from the US FDA for the first SARS-CoV-2 coronavirus/COVID-19 test that will allow individuals to collect their own saliva in the comfort of their homes and send to a lab for testing and results, without risking any exposure in crowded healthcare settings.
The ne...
Source: COVID-19 Diagnostics Apr 18, 2020 4 months ago
COVID-19 Diagnostics: To date, millions of individuals have been tested for the SARS-CoV-2 coronavirus, most using a kit that relies on the polymerase chain reaction (PCR). This sensitive method amplifies SARS-CoV-2 RNA from patient swabs using a thermocycler machine so that tiny amounts of the virus can be detected. But as the crisis surges, this laboratory technique that is time consum...
Source: COVID-19 Diagnostics Apr 17, 2020 4 months ago
COVID-19 Diagnostics: According to an open-access Clinical Perspective article in the American Journal of Roentgenology (AJR), so far the radiology literature on coronavirus disease (COVID-19) pneumonia has consisted of limited retrospective studies that do not substantiate the use of CT as a diagnostic test for COVID-19. https://www.ajronline.org/doi/10.2214/AJR.20.23202
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