WARNING! What They Are Not Telling You! SARS-CoV-2 Is Now Possibly Hyperendemic Globally!
Various SARS-CoV-2 sub-lineages are prevalent across various geolocations literally everywhere across the world but most are causing asymptomatic infections initially!
: Many of you might be confused as to why governments around the world are trying to play down the ongoing COVID-19 situation and also as to why they are relaxing all measures despite stories of people still getting infected and dying or about surges in certain countries or geolocations.
You cannot blame them as economic activity has to go on and there is no use spreading panic among the global population. Rather, it is preferred that things simply go on and the impact of the ongoing crisis is simply being downplayed or concealed. Fortunately, with ignorance a common trait among the masses and a virus that kills slowly in many ways, except for those that are in the vulnerable groups where deaths can be fast but again can be attributed to other causes such as organ failure including heart failure strokes or sepsis etc, it is quite easy to get away even as excess death rates can be manipulated to a certain degree.
Mankind has actually lost all possibility of controlling the spread of the SARS-CoV-2 virus.
The reality of that the SARS-CoV-2 virus is now actually hyperendemic and literally everyone in any geolocation is now at risk of being infected by the virus.
In epidemiology, the term hyperendemic is used to refer to a pathogen or disease which is constantly and persistently present in a population at a high rate of incidence and/or prevalence and which equally affects all age groups of that population. It is one of the various degrees of endemicity.
Unknow to many, the SARS-CoV-2 virus over the years have evolved to all kinds of environmental factors through conformational changes and changes in its folding methods and even through amino-acid substitutions in the critical structural proteins.
It is now better suited to handle vary extreme temperature fluctuations, humidity conditions, pH conditions, salinity and even is developing resistance to UV light, external disinfectants etc.
It has been postulated that even climate changes are to a degree assisting in SARS-CoV-2 evolution.
Studies have also shown that SARS-CoV-2 can be transmitted by winds and even clouds could possibility play a role!
All these helps the SARS-CoV-2 to remain in the environment longer and considering that almost 85 to 92% of all the new SARS-CoV-2 sub-lineages in circulation are only causing asymptomatic infections or very mild symptoms initially during infection and with the issue of viral persistence etc….simply looking at the kinetics of the current SARS-CoV-2 situation, the hypothesis that SARS-CoV-2 is now endemic holds weight.
There is literally very little testing done these days and there is even emerging speculations that there are many more newly emerged SARS-CoV-2 sub-lineages cannot even be detected by the current rapid antigen kits and even by current PCR testing protocols!
Whatever that is being said about new SARS-CoV-2 variants by various platforms and variant hunters online are no longer valid as genomic sequencings are very low and even the GISAID platform is not longer reliable due to control by certain entities and furthermore, many countries are no longer sharing their own genomic sequencing data and some do not even conduct genomic sequencings anymore!
As we have mentioned in a previous COVID-19 News
article, it is only when sub-lineages that have enhanced pathogenicity or changes in tropism that drives disease severity and hospitalizations and when governments cannot conceal such data anymore from the public, that we hear stories in the media about so-called surges etc like in the case of Japan, China and South Korea.
Many of the mysterious respiratory infections or ‘fever diseases’ being reported across various geolocations around the world are nothing more than SARS-CoV-2 infections!
SARS-CoV-2 is not even seasonal like flu but rather is simply prevalent yearlong!
In reality, there is not much difference in any countries anymore, the various SARS-CoV-2 sub-lineages are prevalent in circulation in every geolocation and majority are getting infected or reinfected without even knowing it. Waste water monitoring though effective and is at present showing SARS-CoV-2 presence literally everywhere, the basis of using viral loads to ascertain a surge might not be accurate due to shedding behaviors of various sub-lineages and differences in their pathogenesis and tropisms ie not all fecal or urine samples of infected individuals might exhibit the virus…hence it might not be an effective manner to really show the true extent of the hyperendemic state we are in with regards to SARS-CoV-2!
We have not even talked about other contributing factors that is influencing the hyperendemic state such as various species in the animal kingdom being potential reservoirs, how certain insects are now also vectors for the virus spread and about the virus also being water borne or food borne and even being transmitted sexually! etc.
In actually reality, we are now in the state that there is literally no way that we can escape contact with the virus. It is only a matter of luck if we are fortunate to be exposed to a sub-lineage that only causes asymptomatic infections initially (but we will pay a price later with long term health and medical conditions) or if whether our immunity system has enough ‘capacity’ left to still fend of the virus for a while.
The next few months will be interesting as newer SARS-CoV-2 sub-lineages with enhanced pathogenicity and shift in tropism will add to the mix of circulating and prevailing sub-lineages in this hyperendemic phase and we will be able to witness more chaos however much authorities or mainstream media try to conceal the actual COVID-19 situation!
For the latest COVID-19 News
, keep on logging to Thailand Medical News.