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Nikhil Prasad  Fact checked by:Thailand Medical News Team Oct 21, 2025  4 hours, 12 minutes ago

Brazilian Researchers Warn That COVID-19 Induced Prostatitis Will Eventually Progress into Cancer!

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Brazilian Researchers Warn That COVID-19 Induced Prostatitis Will Eventually Progress into Cancer!
Nikhil Prasad  Fact checked by:Thailand Medical News Team Oct 21, 2025  4 hours, 12 minutes ago
Medical News: Possible Connection Between COVID-19 and Prostate Cancer
Researchers from the State University of Rio de Janeiro in Brazil have reported a concerning medical case suggesting that prostatitis triggered by COVID-19 infection may eventually progress into prostate cancer. This discovery adds to the growing body of evidence that the SARS-CoV-2 virus can have long-term effects on different organs far beyond the lungs.


Brazilian Researchers Warn That COVID-19 Induced Prostatitis Will Eventually Progress into Cancer

In this Medical News report, the scientists detailed the case of a 55-year-old man who developed prostate inflammation shortly after recovering from his second COVID-19 infection. Initially, he had no family history of prostate or breast cancer and no detectable genetic predisposition to cancer. However, after the infection, he began experiencing urinary issues and elevated PSA levels—both early warning signs of prostate problems.
 
From Viral Infection to Cancer Development
Magnetic resonance imaging (MRI) first revealed inflammation consistent with prostatitis. Although antibiotics improved his symptoms, his urinary issues persisted. Over two years, follow-up scans showed the emergence of two prostate lesions—one of them highly suspicious for malignancy. A targeted biopsy confirmed the presence of acinar adenocarcinoma, a common form of prostate cancer.
 
Positron emission tomography (PET-PSMA) confirmed that the disease was confined to the prostate, and treatment combining androgen deprivation therapy and a novel hormonal agent was started. Surgery later revealed a residual cancerous focus showing TMPRSS2::ERG gene fusion and PTEN gene loss—molecular markers often linked to aggressive prostate cancer progression.
 
The Role of TMPRSS2 and Viral Entry
The TMPRSS2 gene, which the SARS-CoV-2 virus uses to enter human cells, is highly active in prostate tissue and regulated by male hormones. The study proposes that inflammation caused by the virus could trigger genetic instability and molecular alterations that promote cancerous transformation, especially in patients with TMPRSS2-linked pathways.

A Warning That Demands Deeper Research
This case marks the first documented evidence suggesting that COVID-19-related prostatitis might play a role in the development of prostate cancer. While the researchers caution that more studies are needed to confirm causation, they emphasize that chronic inflammation induced by the virus could be a key driver of oncogenesis in susceptible individuals. The findings underscore the need for ongoing prostate monitoring in men who have had COVID-19, especially those showing urinary or hormonal irregularities.
 
The study findings were published as an abstract in the peer reviewed journal: Frontiers in Oncology.
https://www.frontiersin.org/journa ls/oncology/articles/10.3389/fonc.2025.1679663/abstract
 
For the latest COVID-19 news, keep on logging to Thailand Medical News.
 
Read Also:
https://www.thailandmedical.news/news/malaysian-researchers-warn-that-covid-19-can-cause-prostatitis
 
https://www.thailandmedical.news/news/researchers-from-china-explore-the-connection-between-prostatic-diseases-and-covid-19
 
https://www.thailandmedical.news/news/covid-19-worsens-prostate-conditions-in-older-men
 

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