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BREAKING NEWS
Source: COVID-19 Drugs  Jul 09, 2020  4 years ago
COVID-19 Drugs: There is now an increased demand for a variety of drugs to treat the growing variety of symptoms and conditions associated with COVID-19. One of which is the assortment of different types of neurological conditions. Just for one neurological category of symptoms which is delirium, BioXcel Therapeutics, which is based in Connecticut has developed a new drug called BXCL510.   ...
Source: COVID-19 Drugs  Jul 09, 2020  4 years ago
COVID-19 Drugs: R-Pharm, a Russian pharmaceutical company has secured regulatory approval for the use of its antiviral drug Coronavir, to treat patients suffering from Covid-19. The company released the announcement today to Russian media.   The regulatory approval comes after a clinical trial in mild to moderate Covid-19 patients showed that the drug is highly effective in blocking replica...
Source: COVID-19 Genomics  Jul 09, 2020  4 years ago
COVID-19 Genomics:  Swiss Researchers from the Institute of Molecular Biology and Biophysics-Zurich, University of Bern and Institute of Virology and Immunology-Bern have discovered the detailed functional process by which the SARS-CoV-2 coronavirus NSP1 Protein Inhibits Host Translation.   Their study published in a preprint server shows that the 5’ end of the RNA molecule is ca...
Source: COVID-19 Disinfectants  Jul 09, 2020  4 years ago
COVID-19 Disinfectants: The American Environmental Protection Agency (EPA) just approved two disinfection sprays that can kill severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), on surfaces. The agency gave the green light to Lysol Disinfectant Spray, and Lysol Disinfectant Max Cover Mist, as two products that can effectively kil...
Source: COVID-19 Nutrition  Jul 09, 2020  4 years ago
COVID-19 Nutrition: A new but intriguing European study involving the collaboration of 13 research centers and universities in Germany, Spain, Portugal, Franca and Switzerland suggests that COVID-19 mortality rates are likely to be lower in countries where diets are rich in fermented vegetables.   Though the study is published on a preprint server, it is currently being peer-reviewed by a f...
Source: COVID-19 Diagnostics  Jul 09, 2020  4 years ago
COVID-19 Diagnostics: Researchers from the University of Exeter have developed a revolutionary new device that could allow health professionals to accurately test patients' antibody response to COVID-19 in as little as seven minutes.   The new pioneering COVID-19 Triple Antibody Test has been produced by the University of Exeter spin-out company Attomarker Ltd and is set to spearhead th...
Source: COVID-19 Alert  Jul 08, 2020  4 years ago
COVID-19 Alert: Medical researchers from Cedars-Sinai Medical Center, Michigan Medicine and UCLA Fielding School of Public Health have found an association between proton pump inhibitors (PPIs) and risk of COVID-19 in an observational study of more than 53,000 Americans.It was found that PPIs usage was linked with a higher risk for COVID-19. This places the usage of PPIs for heartburn and gastric...
Source: COVID-19 Antibodies  Jul 08, 2020  4 years ago
COVID-19 Antibodies: Researchers from Tulane University-New Orleans, University of Illinois-Chicago and University of Georgia have created a synthetic antibody that on mouse models demonstrated to neutralize the SARS-CoV-2 coronavirus. This could help prevent infection as well as treat COVID-19 in those who already have it.   Typically the SARS-CoV-2 coronavirus, gains entry into cells...
Source: COVID-19 Research  Jul 08, 2020  4 years ago
COVID-19 Research: German researchers from Max Planck Institute, Frankfurt Institute for Advanced Studies and the Institute of Biophysics, Goethe University-Frankfurt have conducted a news study on the structural dynamics of the SARS-CoV-2 spike protein and have identified epitopes that could be possible immune targets for the development of vaccines or other therapeutics.   The resear...
Source: COVID-19 Neurology  Jul 08, 2020  4 years ago
COVID-19 Neurology: German researchers from Charité - Universitätsmedizin Berlin have shown that the neurological symptoms observed in some COVID-19 patients may be caused by autoantibodies targeting the brain.   The research team says that although some autoantibodies still need to be identified, they may at least partly explain the multiple organ disease that can occur in COVI...
Source: COVID-19 Drugs  Jul 08, 2020  4 years ago
COVID-19 Drugs: Medical researchers from Queensland University of Technology and Oxford University are working in collaboration to begin human clinical trials of inhaled corticosteroids, commonly used for asthma patients, on patients with COVID-19. The researchers believe that this could be useful for patients with the novel coronavirus infection. Research has shown that some corticosteroids,&nbs...
Source: COVID-19 Innovations  Jul 08, 2020  4 years ago
COVID-19 Innovations: Experts from the University of Houston, in collaboration with a private company called Medistar, have designed a "catch and kill" air filter that can trap the coronavirus responsible for COVID-19, killing it instantly.   Dr Zhifeng Ren, director of the Texas Center for Superconductivity at UH, collaborated with Monzer Hourani, CEO of Medistar, a Houston-based...
Source: COVID-19 Vaccine Updates  Jul 08, 2020  4 years ago
COVID-19 Vaccine Updates: Maryland based Biotech company Novavax announced that it has been awarded US$1.6 billion toward late-stage clinical trials and large-scale manufacturing to produce 100 million doses of its COVID-19 vaccine starting this year through the Trump’s administration “Operation Warp Speed” program.   The new funding will enable Novavax  to complete la...
Source: COVID-19 Neurology  Jul 08, 2020  4 years ago
COVID-19 Neurology:  A new study by University College London (UCL) and University College London Hospitals (UCLH) indicate that more neurological conditions are being manifested in COVID-19 patients. Besides delirium, brain inflammation, stroke and nerve damage, a large number of patients are now shown to be inflicted with ADEM or Acute Disseminated Encephalomyelitis and its prevalence is gr...
Source: Guillain-Barre Syndrome And COVID-19  Jul 08, 2020  4 years ago
Guillain-Barre Syndrome: A new peer-reviewed study published in the Journal of Clinical Neuromuscular Disease by researchers from Department of Neurology and Neuroscience Institute, Allegheny General Hospital Pittsburgh, Pennsylvania show that COVID-19 is linked with Guillain-Barre Syndrome. https://journals.lww.com/jcnmd/FullText/2020/06000/Novel_Coronavirus__COVID_19__Associated.7.aspx   ...
Source: COVID-19 Clinical Care  Jul 08, 2020  4 years ago
COVID-19 Clinical Care: A new study by researchers from Boston Children’s Hospital warns about how and when type III Interferons should be used in the treatment of COVID019 as using it in later stages of severity can do more harm.   The research findings were published in the journal: Science. https://science.sciencemag.org/content/early/2020/06/10/science.abc3545   The human imm...
Source: Otolaryngology  Jul 07, 2020  4 years ago
Otolaryngology: A new study published in the Journal of Medical Genetics shows that a common inherited genetic variant is a frequent cause of deafness in adults with implications that many thousands of people are potentially at risk.   For a long time deafness in adults is known to be inherited. But, unlike childhood deafness, the genetic causes largely remain a mystery, say ...
Source: COVID-19 Research-Liver Fibrosis  Jul 07, 2020  4 years ago
COVID-19 Research: According to researchers in Spain, middle-aged COVID-19 patients showing signs of advanced liver fibrosis, as estimated by the Fibrosis Index Based on 4 Factors (FIB-4), are at greater likelihood of requiring mechanical ventilation.   Dr Luis Ibanez-Samaniego from the  Hospital General Universitario Gregorio Maran, in Madrid who is the lead researcher said that not m...
Source: COVID-19 Warnings- Captopril  Jul 07, 2020  4 years ago
COVID-19 Warnings: A US based study involving researchers from University of Missouri Kansas City School of Pharmacy, Kansas State University and North Carolina State University has found that the high blood pressure drug Captopril to be associated with a higher rate of pulmonary adverse reactions in patients with diabetes than that of other ACE inhibitors or angiotensin receptor blockers (ARBs). ...
Source: COVID-19 Seroprevalence  Jul 07, 2020  4 years ago
COVID-19 Seroprevalence: The Spanish ENE-COVID national seroprevalence study concludes that 5% of its population has antibodies. This percentage has hardly changed in the three waves of which the study consists: in the first it was estimated at 5% and in the second and third it was 5.2%, results that confirm that, despite the great impact of the pandemic in Spain, the figures are not high, which r...
Source: COVID-19 Case Study  Jul 07, 2020  4 years ago
COVID-19 Case Study: Numerous patients with severe COVID-19 remain unresponsive after surviving critical illness. Medical Researchers from Massachusetts General Hospital (MGH) presents  a case in which a patient with severe COVID-19 who, despite prolonged unresponsiveness and structural brain abnormalities, demonstrated functionally intact brain connections when functional MRI was used and we...
Source: COVID-19 Research  Jul 07, 2020  4 years ago
COVID-19 Research: In a new study by researchers from US NIH, Columbia University and John Hopkins University, it has been shown that the SARS-CoV-2 coronavirus is proving itself to be an elusive foe, evading immune surveillance while instigating hyper-inflammatory responses that eventually destroy the host in a significant minority of cases. The study reports the role of pH in helping the virus e...
Source: COVID-19 Vaccine News  Jul 07, 2020  4 years ago
COVID-19 Vaccine News: Biotech manufacturing company-Emergent BioSolutions, based in Maryland, entered a five-year manufacturing services deal with Janssen Pharmaceutical, a Johnson & Johnson company, to manufacture J&J’s Ad26.COV2-S COVID-19 vaccine. Emergent will handle contract development and manufacturing (CDMO) services in a deal that is valued at ...
Source: COVID-19 Antibodies  Jul 07, 2020  4 years ago
COVID-19 Antibodies: New York based Regeneron Pharmaceuticals announced its double-antibody cocktail against COVID-19 is advancing into Phase III studies, less than a month after the start of its first clinical trial, with preliminary data from one study expected to be reported later this summer. Regeneron's Biotech Plant   The biotech company said it is proceeding with clinical develop...
Source: COVID-19 Medical Devices  Jul 07, 2020  4 years ago
COVID-19 Medical Devices: To date, emerging studies suggests that COVID-19 patients are at a higher risk of stroke and promptly diagnosing and treating such patients is a priority in hospitals across the world.   Furthermore, identifying which COVID-19 patients are at increased risk of developing a stroke is also important, and may help with preemptive treatment and monitoring.   Los A...
Source: COVID-19 Vaccine Updates  Jul 07, 2020  4 years ago
COVID-19 Vaccine Updates: It was announced that vaccine candidate COVAX-19 developed by Vaxine Pty Ltd and Flinders University will commence Phase 1 trials at the Royal Adelaide Hospital (RAH) to test its efficacy.   The phase I trial will provide initial safety and immune response data on 40 healthy participants aged between 18 and 65 years who have already been pre-screened.   Resear...
Source: COVID-19 Drugs  Jul 07, 2020  4 years ago
COVID-19 Drugs: Researchers from University of South Florida Health (USF Health) Morsani College of Medicine scientists along with pharmaceutical experts from the University of Arizona College of Pharmacy have identified several existing drug compounds that block replication of the COVID-19 virus (SARS-CoV-2) within human cells grown in the laboratory. The identified inhibitors all demon...
Source: COVID-19 Research  Jul 07, 2020  4 years ago
COVID-19 Research: A new study by  Dr Anna Aksenova, a senior research associate at the Laboratory of Amyloid Biology at St Petersburg University, has advanced a hypothesis that the severe course of COVID-19 may be associated with the von Willebrand factor, a blood glycoprotein that is one of the main components of the blood coagulation system.   The research findings have been peer re...
Source: COVID-19 Research  Jul 07, 2020  4 years ago
COVID-19 Research: A research in which US Military bioweapon researchers tested the stability of the SARS-CoV-2 pathogen on various surfaces, including paper currency and pig skin showed that the novel coronavirus can live for days on animal skin at room temperature and even up to 2 weeks on refrigerated pig skin.   The study has huge implications in the food industry, meat processing plant...
Source : Masks  Jul 06, 2020  4 years ago
We apologize to readers first for posting such an article on our site but we simply just could not resist the kind of stupidity materializing from the COVID-19 pandemic! While many Americans and Europeans are refusing to wear protective mask against the SARS-V-2 coronavirus either due to political reasons or sheer stupidity, across the globe in India, we have the protective mask evolving into a f...
Source: Bubonic Plague China  Jul 06, 2020  4 years ago
Bubonic Plague: China health authorities have reported an outbreak of Bubonic Plague in the inner Mongolia Autonomous Region.   Bubonic plague, caused by bacterial infection, was responsible for one of the deadliest epidemics in human history  ie the Black Death which killed about 50 million people across Africa, Asia and Europe in the 14th Century.   There have been a handful of ...
Source: COVID-19 Genomics  Jul 06, 2020  4 years ago
GOVID-19 Genomics: A major genetic risk variant found on the SARs-CoV-2 coronavirus RNA which comprises of a stretch of six genes that seems to increase the risk of severe illness from the coronavirus was found to be part of a stretch of DNA passed down from Neanderthals 60,000 years ago, according to a new study by genomic experts from the Max Planck Institute for Evolutionary Anthropology-German...
Source: COVID-19 Vaccine  Jul 06, 2020  4 years ago
COVID-19 Vaccine:  Professor of vaccinology at the University of Oxford, and one of the scientists leading the vaccine initiative, Dr Sarah Gilbert, told the U.K.'s Science and Technology Committee last week that their candidate vaccine has progressed to the phase III trial in the United Kingdom.   Phase III trials typically involves tens of thousands of research participants acros...
Source: Flu Vaccine  Jul 06, 2020  4 years ago
Flu Vaccine: Researchers from the Swiss Tropical and Public Health Institute, the University of Basel and University of Sao Paulo Medical School in a new research involving over 92,000 patients with COVID-19 in Brazil shows that the risks of severe disease, ventilatory support requirement, and death are reduced with a recent trivalent influenza vaccine. The research findings were printed on a pre...
Source: COVID-19 Diagnostics  Jul 06, 2020  4 years ago
COVID-19 Diagnostics: A new research from the University of Virginia (UVA) School of Medicine suggests doctors can examine COVID-19 patients' blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a ventilator. The main biomarker that should be looked out for is the cytokine IL-13 (Interleukin 13). High levels of IL-13 were associated with worsened...
Source: Generic Remdesivir  Jul 06, 2020  4 years ago
Generic Remdesivir: The Trump administration last week proudly announced that it had secured 500,000 doses of Gilead’s remdesivir at prices that were set by Gilead at between US$2,340 to US$3,120. https://www.thailandmedical.news/news/breaking-remdesivir-gilead-sets-price-at-us$2,340-to-us$3,120-for-drug-that-has-no-safety-studies-or-true-efficacy-except-that-it-shortens-hospitaliza  ...
Source: SARS-CoV-2 Is Airborne  Jul 06, 2020  4 years ago
WHO: Despite mounting evidence that the SARS-CoV-2 coronavirus is airborne and that the general public worldwide needs to be aware of this, the WHO (World Health Organization) is still taking a stance that it is not the case but is only spread by large respiratory droplets that, once expelled by infected people in coughs and sneezes, fall quickly to the floor.   The  WHO lead by black ...
Source: COVID-19 Diagnostics  Jul 05, 2020  4 years ago
COVID-19 Diagnostics: The US FDA last week  on  granted Emergency Use Authorization to a new molecular diagnostic test from the US Centers for Disease Control and Prevention that can detect and differentiate the viruses that cause COVID-19 and flu.   The new Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay is a real-time RT-PCR test intended for the simultaneous detection and differ...
Source: COVID-19 Innovations  Jul 05, 2020  4 years ago
COVID-19 Innovations: The current COVID-19 pandemic has brought a slew of new challenges for clinical facilities, including how to deliver as much care as possible at a distance or remotely not only for precautionary measures to safeguard the wellbeing of healthcare staff but only for better monitoring of COVID-19 patients..   Researchers from the Department of Cardiovascular Medicine at To...
Source: Autoimmunity  Jul 05, 2020  4 years ago
Autoimmunity: In normal roles, the immune system is supposed to protect from external microbial invaders, but sometimes it turns its efforts inward, potentially resulting in autoimmune diseases.   Researchers from Osaka University In a new study have discovered how reversible modifications to DNA by certain proteins protect from autoimmune diseases, and conversely, how the absence of these ...
Source: COVID-19 And HIV  Jul 05, 2020  4 years ago
COVID-19 And HIV: Individuals with HIV who were hospitalized with COVID-19 did not have worse results than COVID-19 patients without HIV, according to new research by Icahn School of Medicine at Mount Sinai.   The research findings were published in the journal: Clinical Infectious Diseases https://academic.oup.com/cid/article/doi/10.1093/cid/ciaa880/5864410?searchresult=1   Study...
Source:  Jul 05, 2020  4 years ago
COVID-19 Pharma News: Pharma giant Merck, a leading science and technology company, announced that the US FDA has cleared its investigational new drug application (IND) for M5049 for the treatment of patients with Covid-19 pneumonia. Merck will initiate a Phase II randomized, controlled clinical study evaluating the safety and efficacy of M5049 in this patient population. M5049 is a potentially fi...
Source: Melatonin and COVID-19  Jul 05, 2020  4 years ago
Melatonin and COVID-19: Another study by researchers from Peking Union Medical College in China and the University of Texas- San Antonio in America have in a new peer-reviewed finding that is published in the journal: Life Sciences By Science Direct, propose that Melatonin should be incorporated as an adjuvant treatment for COVID-19 as it has proven mechanisms to target Inflammasomes that triggers...
Source: COVID-19 Vaccine  Jul 05, 2020  4 years ago
COVID-19 Vaccine: Researchers from China have created an artificial protein that they say could be the basis of a vaccine to help ward off various deadly coronaviruses, including the pathogen that causes Covid-19 Copyright: Credit: Xinhua    The researchers from the Chinese CDC said the approach triggered a strong antibody response in mice and monkey trials to Middle Eas...
Source: COVID-19 Clinical Care  Jul 04, 2020  4 years ago
COVID-19 Clinical Care: Researchers are expressing that more safety data is needed in terms of treatment of symptomatic COVID-19 patients on antivirals with anticancer drugs.   A report published in the European Journal of Cancer by a group of French investigators led by Dr Paul Gougis of the Department of pharmacology, Hôpital Pitié-Salpêtrière in Paris, Franc...
Source: COVID-19 Drugs  Jul 04, 2020  4 years ago
COVID-19 Drugs: EUSA Pharma has secured approval from the U.S. Food & Drug Administration (FDA) for a Phase III clinical trial protocol of intravenous siltuximab plus standard of care in hospitalized patients with Covid-19 associated Acute Respiratory Distress Syndrome (ARDS). The pharmaceutical company will now proceed with the randomized, double-blind, placebo-controlled clinical trial to e...
Source: COVID-19 Vaccine  Jul 04, 2020  4 years ago
COVID-19 Vaccine:  Indian pharmaceutical company, Zydus Cadila received the green signal from the Drug Controller General of India (DGCI) to start phase I and II of their clinical trials on human participants. Over 120 independent scientific bodies are in contention to find a potential COVID-19 vaccine. Over 7 vaccines are being researched in India and just this week, two candidate groups ...
Source: Thailand Medical News  Jul 04, 2020  4 years ago
The human brain has a high energy demand and reacts very sensitively to oxygen deficiency. Ludwig Maximilian University of Munich neurobiologists have now succeeded for the first time in directly correlating oxygen consumption with the activity of certain nerve cells.   Typically, the brain requires a disproportionate amount of energy compared to its body mass. This energy is mainly generat...
Source: HIV Drugs  Jul 04, 2020  4 years ago
HIV Drugs: The drug Rukobia (fostemsavir) has been approved by The U.S. FDA for adults living with HIV who have tried multiple HIV medications and whose HIV infection cannot be successfully treated with other therapies because of resistance, intolerance or safety considerations. Rukobia (Fostemsavir) is a new type of antiretroviral medication to be taken twice daily by mouth. It is a prodrug, whi...
Source: COVID-19 Vaccine Updates  Jul 04, 2020  4 years ago
COVID-19 Vaccine Updates:  Pharmaceutical and Biotech giants, Pfizer and BioNTech reported that the most advanced of four constructs of their messenger RNA (mRNA) vaccine candidate for COVID-19 showed encouraging immunogenicity and a favorable safety profile in preliminary Phase I/II data published in a preprint study. https://www.medrxiv.org/content/10.1101/2020.06.30.20142570v1   Bot...
Source: COVID-19 Disinfectants  Jul 04, 2020  4 years ago
COVID-19 Disinfectants:  University of Manchester scientists say that a little-known non-toxic antiseptic developed in the Soviet Union during the Cold War has enormous potential to beat common infections and that even detailed studies should be conducted with regards to its use in the current COVID-19 scenario. Their report was published in the journal: FEMS Microbiology Reviews. https://aca...
Source: Chronic Fatigue Syndrome  Jul 04, 2020  4 years ago
Chronic Fatigue Syndrome: There has been so many clinical manifestation of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) reported in COVID-19 patients experiencing mild to moderate symptoms and also in typically asymptomatic and also recovered COVID-19 patients. To date medical experts do not have a proper explanation for this.   However, browsing through various new COVI...
Source: COVID-19 Research  Jul 04, 2020  4 years ago
COVID-19 Research: Researchers from the University Of Bristol in a new review published in the Journal Of Infection indicate that liver complications are common and are associated with more severe disease in patients with COVID-19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306105/ or https://www.journalofinfection.com/article/S0163-4453(20)30425-4/pdf   Dr Setor K. Kunutsor of Bristol M...
Source: COVID-19 Pediatrics  Jul 04, 2020  4 years ago
COVID-19 Pediatrics: Researchers from the University College London Institute of Neurology are warning that children with COVID-19 may present with new neurological symptoms involving the central and peripheral nervous systems, and splenial changes on imaging.   The new research findings were published the journal: JAMA Neurology. https://jamanetwork.com/journals/jamaneurology/fullarticle/2...
Source: COVID-19 Drugs  Jul 03, 2020  4 years ago
COVID-19 Drugs and Erythropoietin: German researchers from the Max Planck Institute of Experimental Medicine in Göttingen suggest that the anemia drug Erythropoietin (Epo) which is sometimes misused as doping agent could also be effective against COVID-19. EPO, the growth factor could also mitigate severe disease progression and protect patients from long-term neurological effects when the ...

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