BA.2.86 News: BREAKING! BA.2.86 Spawning Numerous New Sub-Lineages That Will Ultimately Wreak Havoc Globally Including JN.1, JN.2, JN.3, JQ.1, Etc!
Nikhil Prasad Fact checked by:Thailand Medical News Team Oct 13, 2023 6 months, 2 weeks, 22 minutes ago
BA.2.86 News: The new 2.86 variant that is antigenically different from the Omicron variant as a result of more than 30 new mutations on it, is in a state of rapid evolution despite earlier claims by some Western ‘experts’ on the X platform that is it not mutating that fast!
The B.2.86 variant initially spawned the 2.86.1 offspring.
https://www.thailandmedical.news/news/ba-2-86-news-total-of-36-ba-2-86-sequences-now-found-in-the-united-kingdom-ba-2-86-spawns-new-sub-lineage-ba-2-86-1-with-orf1a-k1973r-mutation
Subsequently it spawned the worrisome JN.1 sub-lineage ie BA.2.86.1.1 with the L455S spike mutation. This JN.1 sub-lineage is also fast growing and some experts predict that it will likely become predominant in late December or early January 2024.
https://twitter.com/JPWeiland/status/1712608303958634726
The JN.1 variant is now found in about 10 countries.
https://twitter.com/RajlabN/status/1712475692364173589/photo/1
There are however numerous other new BA.2.86 sub-lineages spotting unique mutations that have emerged including JN.2, JN.3, JQ.1 and numerous other newer sub-lineages that have yet to be designated!
The JN.2 sub-lineage or BA.2.86.1.2 spots the ORF1a:Y621C mutation.
https://github.com/cov-lineages/pango-designation/commit/62ee71fda492d8305882f8a8611804094501d7f2
https://github.com/cov-lineages/pango-designation/issues/2284
https://github.com/sars-cov-2-variants/lineage-proposals/issues/767
More than a 100 sequences of JN.2 has been found in the United Kingdom, Germany, France, Canada and United States.
The JN.3 sub-lineage or BA.2.86.1.3 has the ORF1a:T2087I mutation and more than 60 sequences of it has been found in various parts of Europe
https://github.com/cov-lineages/pango-designation/commit/8424ad296ae6dd8e78a5ae3247a976eae8dce8dd
The JQ.1 sub-lineage also known as BA.2.86.3.1 has the spike mutation T951 has is concerning as it has been mainly found in hospitalized patients exhibiting disease severity in parts of South Africa, Denmark, France and United Kingdom.
https://github.com/cov-lineages/pango-designation/commit/6c3cbc3ae977feaf9c93e43120e64a1ee3a1a760
While the experts involved in variant identification had access to
13 such sequences so far, there are far more such sequences on GISAID!
Also, there are numerous other BA.2.86 spawns such as the 25 sequences found in South Africa that belong to the BA.2.86.3 sub-lineages but with C222T, C1960T and T12775C mutations.
https://github.com/cov-lineages/pango-designation/commit/bea249add8d5947bc1b1cbea395d5537298983aa
There are 25 sequences of the BA.2.86.2 sub-lineage with the Orf7a: E22D mutation found in Botswana and also South Africa.
https://github.com/cov-lineages/pango-designation/commit/fb96d0a2615265f16525fe555106273f12c53bca
While researchers say that as of the 12
th of October, there has been only 596 sequences of BA.2.86 and its various spawns,
https://twitter.com/RajlabN/status/1712475534926680122/photo/1
there is actually a big backlog of sequences still being processed and being identified and the actually numbers could be much more plus many of the newer sub-lineages have yet to be included!
While Western ‘expert’s again claim in various
BA.2.86 News coverages that BA.2.86 is not that widespread and is not a threat or they claim that there is no evidence that BA.2.86 is causing disease severity or worse their claims that the new vaccines containing the XBB.1.5 spike protein would confer protection against the new BA.2.86 sub-lineages especially using sub-standard vitro studies or small studies involving less than15 human patients that were done conducted by the vaccine manufacturers directly, any intelligent reader would know that all their claims are simply misleading and are actually being controlled by the various big pharma entities who have a vested interest to push the current batch of vaccines first!
In fact, if one was to monitor a few twitter accounts of individuals collating data of the BA.2.86 sequences, you will find that most of the sequences are originating from hospitalized patients, indirectly validating that the BA.2.86 sub-lineages are indeed driving disease severity!
https://twitter.com/HNimanFC
Without wanting to comment too much just yet as we are still awaiting the publication of some new studies conducted by independent researchers on the efficacy of the new vaccines on the emerging BA.2.86 sub-lineages and also the actual spread of the BA2.86 sub-lineages and their growth rates, we warn that that these new BA.2.86 sub-lineages will be among the various other variants and sub-lineages in a variant 'soup' or cluster that are expected to wreak havoc globally in this coming Winter of 2023/2024.
For the latest
BA.2.86 News, keep on logging to Thailand Medical News.
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