Source: Cancer Research UK Aug 08, 2018 4 years ago
It's nearly a decade since the human papillomavirus (HPV) vaccine was first introduced in the UK to help protect against the virus that causes most cases of cervical cancer. But until now, it has only been routinely offered to girls.
Today, the Joint Committee for Vaccination and Immunisation (JCVI) recommended that adolescent boys should now also receive the vaccine.
...
Source: European Molecular Biology Laboratory Aug 08, 2018 4 years ago
The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives. Depending on the bacterial species, some combinations stop antibiotics from working to their full potential whilst others begin to defeat antibiotic resistance.
Combining antibiotics changes their effectiveness.
In the first large-scale screening of its kin...
Source: University Of Geneva Aug 08, 2018 4 years ago
Brain injuries, particularly the milder ones, are difficult to accurately diagnose. CT scanners can help, but often they just don’t have the resolution for clinicians to identify unusual aberrations in the image. Moreover, they expose patients to radiation, are not always available, and the process of using them and evaluating the images produced can take quite some time before results are a...
Source: Massachusetts General Hospital, Boston Aug 08, 2018 4 years ago
Raza M. Alvi, M.D., from Massachusetts General Hospital in Boston, and colleagues compared characteristics, cardiac structure, and outcomes in 394 persons with HIV and heart failure who were receiving PI (145 patients) versus non-PI (NPI; 249 patients) therapy. PI-based antiretroviral therapy contained boosted-dose ritonavir.
Ritonavir-boosted protease inhibitor (PI) therapy is a...
By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected cells.
Human immunodeficiency virus-1 (HIV-1) infection is a chronic disease affecting more than 35 million people worldwide. The infection can be controlled by antiretroviral therapy (ART), but the...
Source: The Journal of Physiology Aug 08, 2018 4 years ago
Eating high fibre foods may reduce the effects of stress on our gut and behaviour, according to new research published in The Journal of Physiology.
Stress is a significant health concern and can cause major changes in the gut and in the brain, which can cause changes in behaviour. In recent years there has been growing interest in the link between gut bacteria and stres...
Source: Society of Nuclear Medicine and Molecular Imaging Aug 08, 2018 4 years ago
Researchers have discovered a new nuclear medicine test that could improve care of patients with type 1 diabetes. The new positron emission tomography (PET) imaging method could measure beta-cell mass, which would greatly enhance the ability to monitor and guide diabetes therapies. This study is reported in the featured article of the month in The Journal of Nuclear Medicine's August issu...
Source: American Heart Association Aug 08, 2018 4 years ago
A new test to assess a whether or not someone is having a heart attack upon arriving in the emergency room was safe and effective, ruling out heart attack in emergency room patients faster than a conventional method, according to new research in the American Heart Association's journal Circulation.
The new high-sensitivity blood test for cardiac troponin, g...
Source: National University Of Singapore Aug 08, 2018 4 years ago
A research team led by scientists from the Cancer Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has developed a novel peptide drug called FFW that could potentially stop the development of hepatocellular carcinoma (HCC), or primary liver cancer. This landmark discovery opens the door for more effective treatment of liver cancer with less side effects.
...
Source: Walter and Eliza Hall Institute of Medical Research Aug 08, 2018 4 years ago
New anti-cancer drugs put cancers to sleep—permanently
In a world first, Melbourne scientists have discovered a new type of anti-cancer drug that can put cancer cells into a permanent sleep, without the harmful side-effects caused by conventional cancer therapies.
Published today in the journal Nature, the research reveals the first class of anti-cancer drugs that work...
Source: Mount Sinai School Of Medicine Aug 08, 2018 4 years ago
A new gene associated with disease severity in models of rheumatoid arthritis has been identified by researchers at the Icahn School of Medicine at Mount Sinai. The discovery could provide a new pathway for treatment and a way to measure the prognosis of patients diagnosed with the autoimmune condition.
Through a series of experiments -- on synovial cells from the inner lining of joints in humans...
Source: University of Virginia Aug 08, 2018 4 years ago
A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases—and possibly even turn back the clock on aging itself.
Irina M. Bochkis, Ph.D., of the University of Virginia School of Medicine, has made a new discovery that could let us prevent or cure diseases such as diabetes and fatty ...
Source: Technical University of Denmark Aug 08, 2018 4 years ago
For decades, researchers have been finding ways to fight disease-causing bacteria in food production without the use of antibiotics. This is because bacteria continuously become resistant to antibiotics due to repeated and improper use.
In a study published in the journal PLOS One, researchers at the National Food Institute of the Technical University of Denmark ha...
Source: Staff Writer, TMN Aug 08, 2018 4 years ago
Is DermaPen Safe?
If you research dermabrasion or micro needling, you’ll eventually come across a little device called DermaPen. This type of tool has become a darling of many skin care professionals and aestheticians, who tout the product to their clients as a new solution for skin tightening, with little or no down time. However, although your local spa or dermatologist office may g...
For patients with the herpes simplex-1 virus (HSV-1), there are just a handful of drugs available to treat the painful condition that can affect the eyes, mouth and genitals.
If patients develop resistance to these drugs, there are even fewer choices left to treat the infection, which lasts for life.
BX795
Researchers at the University of Illinois at Chicago have now identified a ...
Source: University of Connecticut Jul 21, 2018 4 years ago
Despite efforts to eradicate it, syphilis is on the rise. Until now, most health agencies focused on treating infected people and their sex partners but new discoveries may make a vaccine possible, UConn Health researchers report.
The World Health Organization estimates that 10.7 million people between the ages of 15 and 49 had syphilis in 2012, and about 5.6 million people cont...
Chlamydia trachomatis is the main cause of sexually transmitted diseases. More than 131 million people are infected with this bacterium worldwide. If detected at an early stage and treated with antibiotics the infection with Chlamydia can be treated very well. However, infections with Chlamydia develop often without symptoms therefore in many cases remain unnoticed. This promotes the spread o...
Researchers have identified a protein that powers the virulence of the bacteria that causes gonorrhea, opening the possibility of a new target for antibiotics and, even better, a vaccine.
The microbe, Neisseria gonorrhoeae
The findings, published today in PLOS Pathogens, are especially important since the microbe, Neisseria gonorrhoeae, is considered a "superbug" be...
Study paves way for better use of primate models in HIV vaccine development
The mosaic vaccine HIV-1 vaccine produced comparable immune responses in both humans and rhesus monkeys, a phase I/IIa trial found.
In humans, the vaccine was safe and produced antibody responses and T-cell responses, and in monkeys, the vaccine not only produced similar immune responses, but protected again...
Scientists from UNSW Sydney and the UK have discovered that the human immunodeficiency virus (HIV) hijacks a small molecule from the host cell to protect itself from being destroyed by the host's immune system.
Inositol hexakisphosphate fits into the pore structures (pink) of the HIV capsid (teal), and makes the makes the capsid stronger, protecting the genetic material inside. Credi...
Source: USFDA & Staff Writer, TMN Jul 19, 2018 4 years ago
A small percentage of patients, some of whom have taken many HIV drugs in the past, have multidrug-resistant HIV, limiting their treatment options
HIV naturally mutates and eventually develops resistance to ARVs, which are then rendered ineffective. Patients infected with drug resistant strains of HIV are therefore commonly moved to alternative regimens known as 2nd line drugs.
&n...
People living with HIV must take a combination of three or more different drugs every day for the rest of their lives. Unfortunately, by following this strict treatment plan, they can suffer from side effects ranging from mild dizziness to life-threatening liver damage. However, if they stop taking the drugs, the virus hiding inside their cells can spontaneously resurface.
In fact...
Britain's planned exit from the European Union is expected to result in restrictions on EU workers coming to the country, which could create further recruitment difficulties for the NHS.
The British government will loosen immigration rules to allow more doctors and nurses from outside the European Union to come and work for Britain's National Health Service (NHS), the...
In order to expedite service at its hospital, Yanhee Hospital has adopted the practice of getting its nursing aides to use rollerblades to deliver files, test results, x-ray films, prescriptions etc.
However TMN staff observed that none were using helmets and safety gear and neither was there specific zones for them in the hospital , so hospital vissitors and patients need to be more careful!
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Source: Universiti Putra Malaysia Jul 25, 2018 4 years ago
Over-the-counter painkillers like acetaminophen can damage the liver and cause serious health problems. A new study by Malaysian researchers suggested that compounds from a common fern can protect the liver from toxic acetaminophen.
Every day, the liver gets exposed to various substances, many of them toxic. It normally detoxifies and expels those toxic chemicals, but...
Source: University of Colorado School of Medicine Jul 24, 2018 4 years ago
High-concentration peroxide, sometimes promoted in alternative medicine circles for cleanses or as a so-called "natural cure," can lead to numerous life-threatening ailments and death itself, according to a paper published online yesterday in Annals of Emergency Medicine ("Outcomes Following High Concentration Peroxide Ingestions").
"Ingesting high-conce...
Source: Hunan Agricultural University Jul 23, 2018 4 years ago
The medicinal mushroom known as “Reishi ” in Japan was the subject of a recent Chinese study on alternative treatments for recurrent oral ulceration (ROU). The results showed that freeze-dried reishi mushroom powder provided effective treatment for the most prevalent mouth ulcer disease in the world.
ROU is considered an autoimmune disease. It is a frequent complication fo...
Source: The Journal of the American Medical Association Jul 22, 2018 4 years ago
A new study suggests acupuncture could be effective
About half of women ages 40 to 60 experience bladder leaks, or urinary incontinence, according to the American College of Physicians. And a condition called stress incontinence—leaking urine when you cough, sneeze, exercise, or laugh—is one of the most common types.
Treatments, which often include drugs and surgery, can be ...
Source: European Heart Journal Jul 20, 2018 4 years ago
Experts urge caution with daily high-dose vitamin D supplements.
More is not necessarily better when it comes to the use of vitamin D supplements in patients with heart failure, based on results of a recent study published in the European Heart Journal.
Known as the EVITA (Effect of Vitamin D on All-Cause Mortality in Heart Failure) trial, this study looked at the impact of daily ...
Source: American Heart Association Jul 19, 2018 4 years ago
Stem cells from umbilical cords may improve heart function and symptoms.
Stem cells from umbilical cords show promise as a treatment for heart failure, based on a recent study published in the American Heart Association journal Circulation Research.
Known as the RIMECARD trial, this study tested stem cell therapy in 30 patients living with chronic heart failure. The goal was t...
Source: Uppsala Universitet Jul 23, 2018 4 years ago
Epigenetic changes are chemical modifications that turn our genes off or on. In a new study, researchers show that tea consumption in women leads to epigenetic changes in genes that are known to interact with cancer and estrogen metabolism.
Epigenetic changes are chemical modifications that turn our genes off or on. In a new study from Uppsala University, researchers show that tea consum...
Six genes associated with pancreatic cancer have been identified by a research team at Mayo Clinic. The team finds that these genes can be inherited but are also present in patients with no family history of pancreatic cancer.
The team recommends genetic testing for all pancreatic cancer patients as the new standard of care.
‘Six genes contain mutations that can be inherited ...
Scientists examined whether diet may be affecting the success of Helicobacter pylori treatment, and looked at whether nutrients such as cholesterol and omega-3 fatty acids play a role.
Helicobacter pylori is a global health issue responsible for gastritis and gastric ulcers. Approximately 50% of the global population suffers from Helicobacter pylori infection, which...
Source: Beth Israel Deaconess Medical Center Jul 22, 2018 4 years ago
Nearly 30 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Since then, antibiotics have become the primary therapy used to combat the H. pylori infection, which affects approximately six percent of the world population and is also a primary cause of stomach cancer. But today the bacteria is growing increasingly resista...
Source: Massachusetts General Hospital Jul 21, 2018 4 years ago
This week, meat-eaters receive another diet-based kick in the ribs. A new study, published in the journal Gut, links the consumption of red meat to an increased risk of developing diverticulitis.
A recent study uncovers a link between the consumption of red meat and diverticulitis.
Diverticulitis is a relatively common complaint that occurs when bulging sacs appear in the lining...
Source: Reuters, Staff Writer, TMN Jul 23, 2018 4 years ago
Scandal erupts over vaccine safety in China after standards violated
A scandal over faulty vaccines in China has sparked anger on social media, underscoring the difficulties regulators face in rebuilding trust after years of food and drug safety scares.
The incident is a major blow for Beijing's efforts to push domestically made vaccines and for China's drug regulator, which has been str...
Source: Technischen Universität München Jul 20, 2018 4 years ago
The exact cause of irritable bowel syndrome has been unknown. However, scientists have identified an organic cause of irritable bowel syndromes, reveals a new study.
An international team with significant involvement from the Technical University of Munich (TUM) has provided initial clues about the organic triggers of the disease, which affects an estimated one out of six peop...
Studies have shown that people with type 2 diabetes have an increased risk of developing Parkinson’s disease.
Men and women with type 2 diabetes may face a significantly higher risk of developing Parkinson's disease later in life, new British research suggests.
The finding of a link followed the tracking of Parkinson's diagnoses among millions o...
Improved medications for Type 2 diabetes are one step closer thanks to a new discovery reported this week by researchers at the University of Pennsylvania and Syracuse University. By modifying the key ingredient in current diabetes drugs, the researchers produced a compound that was effective for hyperglycemia in animal trials, yet without the most problematic side effects of current drugs.
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Source: Journal Diabetes Care Jul 19, 2018 4 years ago
Improving HbA1c levels could reduce the risk of diabetic polyneuropathy among adults with type 2 diabetes, research suggests.
In a new Danish study, each 1% (11 mmol/mol) increase in HbA1c levels among adults with type 2 diabetes during a 10-year period increased polyneuropathy risk by nearly 66%.
The new research used data from the ADDITION-Denmark study, ...
Source: The North American Menopause Society Jul 20, 2018 4 years ago
Heart disease is still the number one killer of US women, and hormone therapy remains a top treatment for menopause symptoms. A new study connects these two facts to demonstrate little effect of hormone therapy on artery thickness as a precursor to heart disease. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
According...
Source: University of Edinburgh Jul 21, 2018 4 years ago
People infected with HIV are twice as likely to suffer from heart disease, research has found.
Analysis of global figures reveals that HIV-associated cardiovascular disease has more than tripled in the past 20 years as more people are living longer with the virus.
The greatest impact is in sub-Saharan Africa and Asia Pacific regions, with Swaziland, Botswana and Lesotho particularly ...
Source: University of Warwick Jul 20, 2018 4 years ago
A clinical trial of the use of adrenaline in cardiac arrests has found that its use results in less than 1% more people leaving hospital alive—but almost doubles the risk of severe brain damage for survivors of cardiac arrest. The research raises important questions about the future use of adrenaline in such cases and will necessitate debate amongst healthcare professionals, patients and the...
Introduction
High-sensitivity (hs) cardiac troponin (cTn) assays expedite the evaluation of patients with possible acute coronary syndromes (ACS) in the emergency department. Rapid screening protocols with hscTn have been proposed for patients for whom ruling-in or ruling-out acute myocardial infarction (AMI) is the primary issue. These protocols have not included the entire range of patients w...
Source: University of Tsukuba Jul 22, 2018 4 years ago
While many candidate citrullinated antigens have been identified in rheumatoid arthritis (RA) joints, their involvement in blood serum remains mostly uninvestigated. A new study from the University of Tsukuba-centered set out to explore the expression and commonality of citrullinated proteins in peptide glucose-6-phosphate isomerase-induced arthritis (pGIA) and patients with RA. The team also went...
In patients with chronic inflammatory conditions, such as rheumatoid arthritis, there has been limited understanding of how this inflammation affects the brain.
A new study published in Nature Communications examines this issue.
"Rheumatoid arthritis is an inflammatory and autoimmune condition with nasty levels of inflammation that can affect a person'...
Systemic lupus erythematosus (SLE) is a chronic disease that causes inflammation and tissue damage. SLE can involve many organs and systems and has a poor prognosis. It is one of a large group of autoimmune disorders, which occur when the immune system attacks the body's own tissues and organs.
Type I interferon (IFN-I), a key protein that regulates the immune system's activity, i...
Goal is vaccine that targets inflammation in joints
Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions. Such stem cells, known as SMART cells (Stem cells Modified for Autonomous Regenerative Therapy), develop into cartilage cells that produce a biologic anti-inflammatory drug that, idea...
Fast Facts:
Kybella is a nonsurgical injection technique used to reduce excess fat beneath the chin.
Each treatment takes about 15 to 20 minutes.
It uses a synthetic form of deoxycholic acid.
Safety:Kybella was approved by the U.S. Food and Drug Administration (FDA) in 2015.
It’s a well-tolerated alternative to surgical procedures such as liposuction.
Cost:One Kybella treatment costs b...
CoolSculpting, or cryolipolysis, is a nonsurgical body contouring procedure. A plastic surgeon uses a device to freeze fat cells under the skin. Once the fat cells have been destroyed, they are gradually broken down and removed from the body by the liver.
Most CoolSculpting sessions take around an hour and cost about Bt 25,000 per treatment area.
CoolSculping is a fairly new techniq...
Zydus Cadila gets USFDA approval for arthritis drug,Piroxicam.
Zydus Cadila has received final approval from the US health regulator for Piroxicam capsules, used for the treatment of osteoarthritis and rheumatoid arthritis.
According to a BSE filing, Zydus Cadila will market Piroxicam Capsules USP in the strengths of 10 mg and 20 mg. The drug will be produced at the group’s manufa...
Source: Institute for Research in Biomedicine , Barcelona Jul 20, 2018 4 years ago
Scientists in Spain have discovered a mechanism that promotes inflammation-related bowel cancer and could offer new treatment targets.
Researchers may have found a new treatment target for bowel cancer.
The finding concerns the activity of the signaling protein p38 in the myeloid cells of the immune system and that of IGF-1, which is a hormone triggered by p38.
Much of the work was con...
Source: Journal of the American College of Cardiology Jul 20, 2018 4 years ago
Taking heart medication during chemotherapy can help minimize heart damage in breast cancer patients.
A common heart medication may help minimize the toxic effects of chemotherapy, based on a clinical trial that tested the use of beta-blockers in breast cancer patients undergoing chemo. Results of the study were recently presented at the American College of Cardiology’s 67th Annual Sci...
The use of permanent cosmetics dates back thousands of years in history. Microblading, a technique for creating natural looking eyebrows using pigment, has reemerged in popularity in the 21st century, and has rapidly become one of the most popular cosmetic procedures in the United States .However, it has not completely replaced traditional eyebrow micropigmentation techniques: Many peopl...
One of the most promising new technologies for aesthetic treatments is the combination of two methods previously used individually for skin rejuvenation, microneedling and radiofrequency. This combination therapy, known as fractionated radiofrequency, is effective for improvement in acne and acne scars, as well as fine lines and wrinkles, both on and off the face. It can also be used for all skin ...
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