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Thailand Medical News Team  Aug 11, 2023  6 months, 2 weeks, 2 days, 16 hours, 28 minutes ago

Herb-Spice News: Study Shows That Cardamom Helps In Weight Loss, Liver And Mitochondria Health And Prevents Inflammation!

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Herb-Spice News: Study Shows That Cardamom Helps In Weight Loss, Liver And Mitochondria Health And Prevents Inflammation!
Thailand Medical News Team  Aug 11, 2023  6 months, 2 weeks, 2 days, 16 hours, 28 minutes ago
Herb-Spice News: In a groundbreaking revelation, a recent study conducted by Texas A&M AgriLife has unveiled a treasure trove of health benefits nestled within the aromatic embrace of cardamom. Widely known for its exquisite flavor and aromatic allure, and a key component of Indian Chai Lattes, this unassuming spice has now ascended to the status of a "superfood" due to its remarkable impact on appetite, fat loss, and inflammation reduction.


 
The study, led by the distinguished researcher Dr Luis Cisneros-Zevallos, Ph.D., a pioneering horticulture and food science professor at the Texas A&M College of Agriculture and Life Sciences-USA along with scientists from Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ), Mexico delves into the previously untapped potential of cardamom, shedding light on its ability to transform the way we approach weight management, liver health, and overall wellness.
 
Cardamom's Ascendance to Superfood Status
The study team spearheaded a transformative research program aimed at uncovering the intricate connections between horticultural crops and human health. Their latest endeavor, the cardamom study, adds a new dimension to the spice's reputation, positioning it as a powerhouse of health-enhancing properties.
 
This research aligns harmoniously with the department's emphasis on sustainability, wellness, and food security.
 
Cardamom, a cherished ingredient in various global cuisines, has now emerged as a potential agent for battling obesity, enhancing liver function, and mitigating inflammation - an impressive trifecta of health benefits.
 
Past studies and Herb-Spice News coverages has shown that Cardamoms have antioxidant, anti-bacterial, anti-inflammatory and anti-diabetic properties.
 
https://pubmed.ncbi.nlm.nih.gov/36770758/
 
https://www.thepharmajournal.com/archives/2018/vol7issue6/PartI/7-6-102-124.pdf
 
https://www.tandfonline.com/doi/full/10.1080/16583655.2021.2002550
 
https://www.sciencedirect.com/science/article/pii/S2475299123144751
 
https://pubmed.ncbi.nlm.nih.gov/31430531/
 
https://pubs.acs.org/doi/10.1021/jf00011a020
 
https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-017-2068-6
 
https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-017-1979-3
 
https://onlinelibrary.wiley.com/doi/10.1002/jsfa.9617
 
https://www.sciencedirect.com/science/article/abs/pii/S1871402122001370
 
https://www.mdpi.com/2223-7747/10/9/1908
 
Cardamom's Enigmatic Aromatics and Flavor
Hailing from far-flung corners of the globe, cardamom boasts a distinctive profile that marries eucalyptus, mint, and pepper in a warm and herbal embrace. While this spice's aromatic allure has tantalized palates for centuries, its newfound role as a health-promoting dynamo elevates it beyond a mere culinary delight.
 
Cardamom's Multifaceted Health Effects Unveiled
The study conducted extensive experiments, employing live animal subjects to uncover the depths of cardamom's potential. These trials revealed that cardamom achieves a delicate equilibrium between stimulating appetite and inducing energy expenditure and fat mass reduction. Surprisingly, the spice managed to not only increase appetite and food consumption but also initiated calorie burning processes within the body.
 
These combined effects offer a promising solution for weight management and metabolic health
 
To translate these findings into human context, the study elucidated estimated dosages: a minimum of 77 milligrams of cardamom bioactives for an adult weighing around 132 pounds. This beneficial dosage can be easily obtained by consuming eight to ten cardamom pods each day. Such insights offer a practical path for individuals to harness cardamom's potent effects in their pursuit of improved health.
 
The research, conducted on live animal subjects, demonstrated that diets enriched with cardamom seeds led to decreased fat accumulation and increased lean body mass, ultimately contributing to weight loss.
 
Furthermore, the study unveiled cardamom's role in promoting mitochondrial health, a crucial factor in maintaining overall vitality. The spice was shown to enhance mitochondrial oxidative metabolism in both liver and skeletal muscle. This enhanced energy production translates to improved bodily functions and increased metabolic efficiency.
 
Cardamom's Influence on Vital Neural Circuits
Beyond its impact on appetite and fat metabolism, cardamom demonstrated a remarkable ability to influence neural circuits crucial for regulating adipose tissue lipolysis and mitochondrial oxidative metabolism in vital organs such as the liver and skeletal muscle. This intricate modulation of neural pathways represents a profound breakthrough in understanding cardamom's systemic effects on the body's metabolic processes.
 
The Promise of Inflammation Prevention
Furthermore, the research has illuminated cardamom's potential as a potent anti-inflammatory agent. Chronic low-grade inflammation, a precursor to an array of debilitating diseases, can be stifled by cardamom's unique properties. By mitigating this silent threat, cardamom has positioned itself as a valuable ally in the ongoing battle against pervasive health challenges.


Parallel central and peripheral effects of cardamom intake regulating energy metabolism. The different compounds present in cardamom seeds exerted central and peripheral effects modulating energy balance in mice. Central effects include the modulation of NPY and POMC expression, the hypothalamic peptides controlling food intake and energy expenditure, probably by activation of the GABAA receptor. The activity of the TRH and CRH neurons in the paraventricular nucleus (PVN) are also modulated by GABAA receptors. These neurons regulate the circulating levels of triiodothyronine (T3) and corticosterone. The metabolic activities of T3 in peripheral tissues include the activation of uncoupling protein 1 (UCP-1) mediated thermogenesis in brown adipose tissue. Cardamom seeds also exerted peripheral effects in adipose tissue, skeletal muscle and the liver, in part by increasing AMP-activated protein kinase (AMPK). AMPK signaling in adipose tissue increased lipolysis by activation of hormone sensitive lipase (HSL). In skeletal muscle and liver, AMPK increases oxidative capacity by increasing mitochondrial biogenesis and activity. Conversely, chronic corticosterone signaling impairs mitochondrial biogenesis and function. Thus, the reduction in circulating corticosterone by cardamom consumption favors oxidative metabolism in metabolic tissues, reducing body fat by increasing lipolysis and whole-body energy expenditure through augmented mitochondrial activity in skeletal muscle and liver. Upwards arrow = upregulation, downwards arrow = downregulation.

Economic Opportunities and Global Impact
As these revelations unfold, the economic implications for both health-conscious consumers and cardamom-producing regions are immense. Guatemalan farmers, numbering over 350,000, have practiced sustainable cardamom shade-farming in tropical forests - a practice that now stands validated and potentially lucrative due to cardamom's newfound status as a wellness superstar. By broadening its usage across international markets, cardamom could provide stability to farmers and even play a role in addressing immigration crises.
 
The Journey from Lab to Lifestyle
The implications of the Texas A&M AgriLife study extend far beyond laboratory confines. As cardamom emerges from relative obscurity to occupy the spotlight of scientific inquiry, its journey continues into kitchens and dietary regimes worldwide. By embracing this aromatic gem, individuals can harness its multifaceted benefits to aid in weight management, enhance liver health, and shield against inflammation-related maladies.
 
Looking Forward - Cardamom's Potential as a Coadjuvant
The future beckons with exciting possibilities as cardamom, armed with its newfound status as a promoter of holistic health, steps into the limelight.
 
Industries ranging from sports nutrition to functional foods and dietary supplements stand to benefit from incorporating cardamom's bioactive compounds into their offerings. The diverse avenues for cardamom's application underscore the multi-faceted nature of this spice and its potential to revolutionize various sectors.
 
From the Mountains of Guatemala to Global Wellness
As the sun sets over the lush cardamom plantations nestled in the Guatemalan mountains, a new dawn emerges for this once-hidden treasure. The journey from obscurity to superfood status charts an inspiring trajectory, one that showcases the symbiotic relationship between scientific inquiry, cultural traditions, and human well-being. As cardamom's unique aroma and flavor continue to tantalize our senses, its profound impact on weight management, liver health, and inflammation prevention invites us all to savor the future of wellness, one delectable pod at a time.
 
The study's findings, published in the prestigious peer reviewed International Journal of Molecular Sciences, reverberate across culinary and scientific circles alike.
https://www.mdpi.com/1422-0067/24/4/3909
 
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