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BREAKING NEWS
Source: COVID-19 Prophylactics-Therapeutics  Dec 14, 2021  2 years, 4 months, 4 days, 8 hours, 3 minutes ago

BREAKING! Latest German Study Reinforces Past Research Showing Iota-Carrageenan Ability To Inhibit Replication Of All SARS-CoV-2 VOCs.

BREAKING! Latest German Study Reinforces Past Research Showing Iota-Carrageenan Ability To Inhibit Replication Of All SARS-CoV-2 VOCs.
Source: COVID-19 Prophylactics-Therapeutics  Dec 14, 2021  2 years, 4 months, 4 days, 8 hours, 3 minutes ago
COVID-19 Prophylactics-Therapeutics: Scientist from Friedrich-Alexander University Erlangen-Nürnberg-Germany, Ulm University Medical Center-Germany, University Hospital Tübingen-Germany and Marinomed Biotech AG-Austria have in a new study found that the safe and non-toxic natural compound iota-carrageenan has the ability to inhibit replication of all existing SARS-CoV-2 variants of concern or VOCs. The latest study findings reinforce numerous previous research showing the ability of iota-carrageenan as an antiviral against various viruses including the SARS-CoV-2 coronavirus.


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The study team investigated the antiviral effect of iota-, lambda- and kappa-carrageenan, sulfated polysaccharides extracted from red seaweed, on SARS-CoV-2 Wuhan type and the spreading variants of concern (VOCs) Alpha, Beta, Gamma and Delta. Carrageenans as part of broadly used nasal and mouth sprays as well as lozenges have the potential of first line defense to inhibit the infection and transmission of SARS-CoV-2.
 
The study team demonstrate by using a SARS-CoV-2 spike pseudotyped lentivirus particles (SSPL) system and patient-isolated SARS-CoV-2 VOCs to infect transgenic A549ACE2/TMPRSS2 and Calu-3 human lung cells that all three carrageenan types exert antiviral activity. Iota-carrageenan exhibits antiviral activity with comparable IC50 values against the SARS-CoV-2 Wuhan type and the VOCs.
 
The study findings indicate that iota-carrageenan might be effective for prophylaxis and treatment of SARS-CoV-2 infections independent of the present and potentially future variants.
 
The study findings were published in the peer reviewed International Journal of Molecular Sciences. https://www.mdpi.com/1422-0067/22/24/13202
 
Thailand Medical News had already covered about the use of iota-carrageenan as both a prophylactic and therapeutic antiviral compound as early as August 2020.