Thailand Coronavirus News is a section dedicated to the new coronavirus that is causing an epidemic in China and fast spreading globally. The strain of coronavirus called Covid-19 or also commonly called the Wuhan coronavirus is genetically more potent and faster spreading than the SARS coronavirus. Currently teams are working to develop a new vaccine for this new coronavirus while other teams are...
Source: COVID-19 Clinical Care Jul 26, 2020 2 years ago
COVID-19 Clinical Care: A recent study published in American Journal of Roentgenology (AJR),indicates that lung ultrasound (US) was highly sensitive for detecting abnormalities in patients with COVID-19 disease, with B-lines, a thickened pleural line, and pulmonary consolidation the most commonly observed features. https://www.ajronline.org/doi/10.2214/AJR.20.23513
The usage of l...
Source: COVID-19 Vaccine News Jul 26, 2020 2 years ago
COVID-19 Vaccine News: Dynavax Technologies, a fully-integrated biopharmaceutical based in California has partnered with Taiwan-based Medigen Vaccine Biologics to develop a new adjuvanted Covid-19 vaccine candidate.
The new collaborative vaccine development will leverage on Medigen’s stable prefusion form of the SARS-CoV2 recombinant spike protein in combination with Dynavax&rs...
COVID-19 News: Researchers from Singapore’s Duke-NUS Medical School have discovered SARS-CoV-2-specific T cell immunity in recovered COVID-19 and SARS patients and in uninfected individuals as well. The Singapore study shows that SARS-CoV-2-specific T cells are present in all recovered COVID-19 patients and interestingly these T cells were also found in all subjects who recovered f...
Source: COVID-19 Antibodies Jul 26, 2020 2 years ago
COVID-19 Antibodies: A new study led by scientists from Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.
By reviewing data on nearly 300 anti-SARS-CoV-2 antibodies that their labs and others have found in convalescent COVID-19 patients over the past few months, the r...
COVID-19 Drugs: Researchers from Rensselaer Polytechnic Institute-New York, Korea Research Institute of Bioscience and Biotechnology, and Zhejiang University of Technology-China in study involving the test of antiviral effectiveness against the virus that causes COVID-19, found that an extract from edible seaweeds called fucoidan substantially outperformed remdesivir, the current standard antivira...
Source: COVID-19 Diagnostics Jul 25, 2020 2 years ago
COVID-19 Diagnostics: Korean researchers in a new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.
The researchers suggest that a...
Source: COVID-19 Research Jul 25, 2020 2 years ago
COVID-19 Research: A study led by researchers at Karolinska Institutet published in Emerging Microbes & Infections gives new insights into the virus-host interplay enabling newer perspectives about how to tackle the virus. https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1799723
The prevailing COVID-19 pandemic caused by the novel coronavirus has created an unprecede...
Source: COVID-19 Innovations Jul 25, 2020 2 years ago
COVID-19 Innovations: Scientists from George Washington University (GW) have developed a miniscule device that could allow public health professionals to immediately diagnose and track COVID-19 infection using cell phones.
The university’s Technology Commercialization Office (TCO) awarded a US$50,000 COVID-19 Technology Maturation Grant to the team, led by Dr Mona Zaghloul and...
Source: COVID-19 Research Jul 25, 2020 2 years ago
COVID-19 Research: Researchers from the Pennington Biomedical Research Center at Louisiana State University System have established a possible link between the hormone Leptin and the increased risk of severity and mortality in obese COVID-19 patients.
Leptin is a hormone that connects the body's metabolism and immune response system and it may explain why the COVID-19 idisease is so d...
Source: COVID-19 Genomics Jul 25, 2020 2 years ago
COVID-19 Genomics: Research in Netherlands led Radboud University Medical Center-Nijmegen have uncovered that host variants of the X chromosomal gene called TLR7 could be one of the factors that leads to severity in COVID-19 patients.
The research findings were published in the JAMA journal. https://jamanetwork.com/journals/jama/fullarticle/2768926
Present observations suggest that...
Source: COVID-19 Genomics Jul 24, 2020 2 years ago
COVID-19 Genomics: Researchers from the University of Texas Health Science Center at San Antonio (UT Health San Antonio) have discovered how the non-structural protein 16 (nsp16) of the SARS-CoV-2 , in conjunction with nsp10, methylates the 5′-end of virally encoded mRNAs to mimic cellular mRNAs, thus protecting the virus from host innate immune restriction.
The research findi...
Source: COVID-19 Pandemic Jul 24, 2020 2 years ago
COVID-19 Pandemic: The world is about 6 months (Note that on January 23, 2020, WHO chief Tedros publicly described the spread of the new coronavirus in China as “limited.”, and only on January 30, 2020,The World Health Organization finally declares it an international health emergency but not a pandemic just yet) into the COVID-19 pandemic and to date, we have officially more than...
Source: COVID-19 Diagnostics Jul 24, 2020 2 years ago
COVID-19 Diagnostics: Israeli biotech company, Nanoscent has developed a SARS-CoV-2 coronavirus breathalyzer test that gives results in less than 30 seconds, billing it as a "front line" tool that can help restore a sense of normality during the pandemic.
The breathalyser is not meant to replace lab tests, but is a mass screening tool
The company said an extensive trial in Israe...
Source: COVID-19 Research Jul 24, 2020 2 years ago
COVID-19 Research: Scientists from the Rockefeller University-New York, New York Blood Center, Università della Svizzera italiana,-Switzerland and Howard Hughes Medical Institute have discovered in a new study that mutated SARS-Cov-2 spike protein variants can evade neutralizing antibodies .
Furthermore the researchers warn that the emergence of antibody-resistant SARS-CoV-2 varian...
Source: COVID-19 Hand Sanitizer Jul 24, 2020 2 years ago
COVID-19 Hand Sanitizer: CAGE Bio Inc., a California based biotech startup announced discovery of a novel hand sanitizer that offers long-lasting protection from the SARS-CoV-2 coronavirus and other harmful viruses, bacteria, and fungi. It kills germs on contact and, unlike common hand sanitizers, provides protection against their transmission for more than four hours after applying to skin....
US COVID-19 News: As Of 2.30am (California, Thursday 23rd July), the number of newly infected COVID-19 cases over the last 24 hours(for the 22nd of July) is now 63,782 with numbers still expected to rise due to delays of reporting by certain counties and states. This brings the total number infected in the United States to 4,001,315 ( we do not base our figures on John Hopkins Dashboard or the US ...
U.S. News: America has indicted two Chinese nationals for hacking into the computer systems of hundreds of companies, governments, non-governmental organizations and more to steal trade secrets, including data on treatments related to COVID-19 for themselves and in certain cases for the Chinese Government according to the charge sheets.
The American Department of Justice indicted Li Xi...
COVID-19 Vaccine: California based Arcturus Therapeutics Holdings Inc., a clinical-stage messenger RNA medicines company focused on the discovery, development and commercialization of therapeutics for rare diseases and vaccines, and Duke-NUS Medical School, Singapore's flagship research-intensive graduate entry medical school, announced that the Clinical Trial Application for COVID-19 vaccine ...
Source: COVID-19 Genomics Jul 23, 2020 2 years ago
COVID-19 Genomics: A new genomic and molecular biology study by American and Chinese researchers from the Chinese Academy of Sciences-Shanghai, Harvard Medical School, University Of Michigan, Fudan University –Shanghai and various genomic labs in China has revealed that the SARS-CoV-2 coronavirus is mutating and evolving constantly to evade the human immunity responses.
The st...
UK Medical News: Medical experts at the Academy of Medical Sciences (AMS) are warning that Britain must prepare now for a potential new wave of COVID-19 infections that could be worse than the first.
The report: Preparing for a challenging winter 2020/21 calls for ‘intense preparation’ throughout the rest of July and August to reduce the risk of the health service be...
Source: SARS-CoV-2 Mutations Jul 23, 2020 2 years ago
SARS-CoV-2 Mutations: University Of Bath and University Of Edinburgh scientists investigating the evolution of the SARS-CoV-2 coronavirus that causes COVID-19 say that its mutation seems to be directed by human proteins that degrade it, but natural selection of the virus enables it to bounce back. The findings could help in the design of vaccines against the virus.
The research findings a...
COVID-19 Drugs: Heron Therapeutics, Inc, a commercial-stage biotechnology company announced the initiation of the GUARDS-1 Study, a Phase 2 clinical study evaluating CINVANTI (aprepitant) injectable emulsion in early hospitalized patients with COVID-19.
The research study initiation follows clearance from the U.S. FDA of Heron's Investigational New Drug application for CINVANTI for th...
Source: COVID-19 Antibodies Jul 22, 2020 2 years ago
COVID-19-Antibodies: Researchers from Columbia University Irving Medical Center have isolated antibodies from several COVID-19 patients that, to date, are among the most potent in neutralizing the SARS-CoV-2 virus.
These isolated potent antibodies could be produced in large quantities by pharmaceutical companies to treat patients, especially early in the course of infection, and to preven...
COVID-19 News: Researchers have known for several months now that the SARS CoV-2 coronavirus can become suspended in microdroplets expelled by patients when they speak and breathe, but until now there was no real scientific evidence that these tiny particles are infectious.
A recent study by scientists at the University of Nebraska that was uploaded to a medical preprint site this week ha...
COVID-19 Drugs: Biophramaceutical company Sorrento Therapeutics, Inc. has received clearance from the US FDA to initiate a Phase 2 trial of Abivertinib in patients with COVID-19 who have moderate to severe pulmonary symptoms.
The drug Abivertinib is a novel small molecule tyrosine kinase inhibitor (TKI) that selectively targets both mutant forms of the epidermal growth factor receptor (EG...
Source: COVID-19 Vaccine Progress Jul 22, 2020 2 years ago
COVID-19 Vaccine Progress: The Phase ½ clinical trial of BioNTech And Pfizer’s BNT162b1 RNA-Based Vaccine has demonstrated that the vaccine is able to elicit both T Cell And Neutralizing Antibodies Response.
The trial results were published by researchers from Germany and the United States on a preprint server and are yet to have been peer-reviewed. https://www.medrxiv.org/co...
Source: COVID-19 Scandals Jul 22, 2020 2 years ago
COVID-19 Scandals: Remdesivir is coming under more spotlight as more doctors questions its effectiveness not only in terms of its ability to cut death rates but also on its claims to shorten hospitalization stays. https://www.bmj.com/content/370/bmj.m2839
Many subsequent studies that emerged after the criticisms seems suspicious as some look as if the researchers or institutions wer...
Source: COVID-19 Heart Issues Jul 22, 2020 2 years ago
COVID-19 Heart Issues: Autopsies of COVID-19 patients by researchers from the department of pathology at Louisiana State University Health Sciences Center in New Orleans have revealed shocking damage to the hearts of COVID-19 patients that are not expected from typical inflammation of the heart muscle associated with myocarditis. Rather there was a unique pattern of cell death in scatter...
Source: COVID-19 Warnings Jul 22, 2020 2 years ago
COVID-19 Warnings: Researchers from Princeton University-USA, Georgia Institute of Technology-USA and McMaster University-Canada based on a new statistical study are warning that asymptomatic spread of the COVID-19 disease is likely to extend the duration of the COVID-19 pandemic coupled with more worsening effects.
The research findings were published in the journal: Epidemics. https://w...
COVID-19 Drugs: According to researchers from the George Washington University (GW), nitric oxide treatment can be pivotal in the world's fight against SARS-CoV-2, the coronavirus that causes COVID-19. A review article on its usage is published in the journal Nitric Oxide. https://www.sciencedirect.com/science/article/pii/S1089860320301701?via%3Dihub
As a pharmaceutical compound,...
Source: COVID-19 Treatment Protocols Jul 21, 2020 2 years ago
COVID-10 Treatment Protocols: Dutch researchers from Zuyderland Medical Center-Heerlen and Leiden University Medical Center-Zuid have developed a treatment protocol to reduce cytokine storm mortality in COVID-19 patients undergoing severe stages of the disease.
The journal of the European League Against Rheumatism (EULAR) - The Annals of the Rheumatic Diseases has published findings ...
Source: COVID-19 Reinfections Jul 21, 2020 2 years ago
COVID-19 Reinfections: As early as late February, Thailand Medical News was reporting about cases of COVID-19 reinfections occurring in China from data supplied by Chinese researchers on the frontlines, https://www.thailandmedical.news/news/latest-more-cases-of-coronavirus-reinfections-emerging-among-cured-patients-in-china-causing-concern but many times Western Researchers (mostly those not ...
Source: COVID-19 Vaccine Updates Jul 21, 2020 2 years ago
COVID-19 Vaccine Updates: The clinical trial results of the Phase I/II trial of Oxford University and AstraZenaca’s ChAdOx1 nCoV-19 vaccine published in the scientific journal, The Lancet, indicate no early safety concerns and induces strong immune responses in both parts of the immune system. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltext
The ChA...
COVID-19 Vaccine: The phase 2 trial of China’s Ad5 vectored COVID-19 vaccine candidate that was conducted in Wuhan has found that the vaccine is safe and induces an immune response, according to trial findings published in The Lancet. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31605-6/fulltext#%20
The phase 2 randomized trial sought to evaluate the ...
Source: COVID-19 Research Jul 21, 2020 2 years ago
COVID-19 Research: A new study by researchers from University of Bristol-UK, University of California-San Diego and Oxford Brookes University has revealed that the spike proteins of the SARS-CoV-2 coronavirus has a high affinity for the nicotinic acetylcholine receptors (nAChRs) of human host with significant implications for pathology and infectivity of the COVID-19 disease.
The fact tha...
Source: COVID-19 Nutrition Jul 21, 2020 2 years ago
COVID-19 Nutrition: A study by researchers in Europe claims that COVID-19 mortality rates may be lower in countries where individuals consume high amounts of cabbage and cucumber.
Increasing average daily consumption of the vegetables by 1 gram may cut mortality rate, according to research, which has not been peer-reviewed. The research findings are published on a preprint server. https:/...
Source: COVID-19 Ventilators Jul 21, 2020 2 years ago
COVID-19 Ventilators: A recent study by researchers from University Of Liverpool and Liverpool University Hospitals show that the administration of continuous positive airway pressure (CPAP) may help in avoiding mechanical ventilation in COVID-19 patients.
The results of the study are significant as CPAP is less invasive and less costly than invasive ventilation.
The research findi...
Source: COVID-19 Diagnostics Jul 21, 2020 2 years ago
COVID-19 Diagnostics: According to newly published research from cardiologists at the University of Alberta, a new blood test that reliably predicts outcomes for heart failure patients could lead to new diagnostics and treatments for COVID-19 patients as well.
The medical researchers examined circulating angiotensin peptide levels in the blood of 110 people who were experiencing hear...
Source: COVID-19 Medications Jul 20, 2020 2 years ago
COVID-19 Medications: Synairgen, a British biotech company announced positive results from a clinical trial of its wholly-owned inhaled formulation of interferon beta in COVID-19 patients.
Synairgen indicated its nebulizer treatment resulted in a 79% lower risk of patients developing severe disease compared to those receiving a placebo. And the patients receiving the treatment &...
Source: Healthcare Innovations Jul 20, 2020 2 years ago
Healthcare Innovations: Researchers from Northeastern University-Boston have created a new sensor that is capable of detecting the SARS-CoV-2 coronavirus particle in the air. The new sensor would be a major game changer in the management of the current COVID-19 pandemic.
A gas sensor used to detect airborne SARS-CoV-2 virus in Professor Nian Sun’s lab in Egan
Research Center. Credit: Ruby ...
Source: Medical Innovations Jul 20, 2020 2 years ago
Medical Innovations: Researchers led by Massachusetts Institute of Technology along with colleagues from University of Seville-Spain, Benefits Science Technologies-Boston, Hartford HealthCare-Connecticit, Azienda Socio-Sanitaria Territoriale di Cremona-Italy and HM Hospitals Spain have created a new online COVID-19 Mortality Risk calculator for all healthcare professionals and even laymen to...
Source: COVID-19 Symptoms Jul 20, 2020 2 years ago
COVID-19 Symptoms: Researchers from King’s College London and Massachusetts General Hospital by detailed analysis of data from the COVID Symptom Study have identified six distinct ‘types’ of COVID-19, each distinguished by a particular cluster of symptoms.
The research team found that these types differed in the severity of the disease and the need for respiratory support duri...
Source: Hong Kong COVID-19 News Jul 20, 2020 2 years ago
Hong Kong COVID-19 News: SARS-CoV-2 infections are escalating and spreading out of control in Hong Kong with a record 108 new cases confirmed, the finance hub's leader said Sunday as she tightened social distancing measures to tackle the sudden surge in infections.
Hong Kong was one of the first places to be struck by the virus when it emerged from central China. However the city had ...
Source: COVID-19 Supplements Jul 20, 2020 2 years ago
COVID-19 Supplements: Vitamin D could play a supporting or adjuvant role in the treatment of COVID-19 disease as it is able to shut down certain pro-inflammatory responses to the SARS-CoV-2 coronavirus in a timely manner according to a new collaborative research involving 10 medical research entities and institutions including Imperial College London-UK, University of Oxford-UK, The U.S. National ...
COVID-19 News: Just when things could not become more complicated and worse, scientist have discovered a new hybrid strain of the fungus Aspergillus latus that is even more drug-resistant and worse it was found in certain COVID-19 patients causing serious lung infections and giving medical researchers new ‘headaches’ to deal with not one but two different dangerous pathogens.
...
Pharma News: One of the world’s biggest pharma giant Novartis, in a PR move publicly announced the launch an initiative to assist patients in low-income and lower-middle-income countries in getting access to affordable drugs for COVID-19.
The pharma company said that they are specifically making 15 drugs from its Sandoz division available that can be used to treat symptoms...
COVID-19 Drugs: Leading Biopharmaceuticals company Biocon has secured approval from the Drugs Controller General of India (DCGI) for its plaque psoriasis drug Itolizumab (ALZUMAb) for emergency use in Covid-19 patients.
The regulatory approval is for 25mg / 5ml injection solution of the medicine to treat cytokine release syndrome (CRS) in moderate to severe acute respiratory distress synd...
Source: COVID-19 Research Jul 20, 2020 2 years ago
COVID-19 Research: German researchers and virologists from the University Of Munich and Institute of Molecular Virology, ULM University have discovered that the spike protein Nsp1 from the SARS-Cov-2 has a central role in weakening the host anti-viral immune response by effectively shutting down production of proteins in the host.
It was found that the SARS-CoV Nsp1 induces a ...
COVID-19 Vaccine: It was announced that the First Phase-III clinical trial of Chinese state-owned pharmaceutical company Sinopharm's inactivated Covid-19 vaccine has started in Abu Dhabi.
Head of Abu Dhabi’s health department becomes first volunteer for
Covid-19 Phase III Chinese vaccine trials
Interestingly the UAE health authorities recently issued a permit for up to 15,000 vo...
Source: COVID-19 Supplements Jul 19, 2020 2 years ago
COVID-19 Supplements: A New study by researchers from Yale University show how lipidomic disruption and changes mark the severity of COVID-19 disease especially the start and progression of cytokine storms.
The research finding that is yet to be peer-reviewed is published on a preprint server. https://www.medrxiv.org/content/10.1101/2020.07.09.20149849v1
The research indirectly als...
Source: COVID-19 Supplements Jul 19, 2020 2 years ago
COVID-19 Supplements: Researchers from Spain, Peru and Colombia have collaborated to conduct a series of studies on the herb called Uncaria Tomentosa or Cat's claw on its efficacy against the SARS-CoV-2 coronavirus.
In an initial study using computational silico molecular docking analysis, it was found that the certain phytochemicals in the herb could inhibit the protease MPro re...
Source: COVID-19 Immunophenotyping Jul 19, 2020 2 years ago
COVID-19 Immunophenotyping: A major of the sign of SARS-CoV-2 infection is the broad-spectrum of disease severity. COVID-19 usually results in a mild disease course that resolves on its own. However, about 8 to 12% of patients develop severe symptoms that require intensive care with mechanical ventilation. Understanding this distinction, and uncovering the cause of the difference between mild dise...
COVID-19 Drugs: Iran is one of the worse hit countries by the COVID-19 crisis and initially as a result of drug shortages and misinformation, Iranian physicians were using hydroxychloroquine (HCQ) to treat many of its patients but as the lethal effects of the drug became known, many local researchers turned to drug-repurposing studies to find alternatives.
One such identified drug was Febuxostat....
Source: COVID-19 Supplements Jul 19, 2020 2 years ago
COVID-19 Supplements: Scientists from the Wuhan University of Bioengineering in China say that curcumin, a natural compound found in the spice turmeric, could help eliminate certain coronaviruses especially an alpha-group coronavirus that infects pigs.
The new research in China showed that curcumin can prevent transmissible gastroenteritis virus (TGEV), an alpha-group coronavirus that inf...
Source: COVID-19 Research Jul 19, 2020 2 years ago
COVID-19 Research: Researchers from Cleveland Clinic and Case Western Reserve University have identified genetic factors that may influence susceptibility to COVID-19.
These findings could pave the way for a personalized medicine approach for treating COVID-19 as it is emerging more day by day that COVID-19 is a highly complex disease with different pathogenesis paths in different i...
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