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Covid-19 Drugs
Covid-19 Drugs
Source: Ivermectin And COVID-19  Jun 21, 2020  1 year ago
Ivermectin and COVID-19: Despite initial molecular docking studies and vitro studies showing a potential of using Ivermectin to treat COVID-19, there has only been a few clinical trials and even then despite having positive results, not much is talked about Ivermectin as its basically a drug whose patent has lapsed and hence it is not profitable for many pharmaceutical giants to promote it. To als...
Source: Azithromycin and COVID-19  Jun 21, 2020  1 year ago
Azithromycin: In a new study published in the Oxford Journal: Open Forum Infectious Disease, researchers Dr Jeniffer Lighter and Dr Vanessa Raabe from New York University School of Medicine warn against the use of the antibiotic azithromycin to treat COVID-19. https://academic.oup.com/ofid/article/7/6/ofaa207/5849083   In the mad scramble to find drugs to treat COVId-19 and the testing of v...
Source: Cannabis And COVID-19  Jun 20, 2020  1 year ago
Cannabis And COVID-19: According to researchers from Harvard Medical School, Northeastern University, Concordia University of Wisconsin and Vilotos Pharmaceuticals Inc, Caflanone (FBL-03G) a flavonoid extracted from a rare strain of cannabis found in Jamaica called Black Swan could hold therapeutic properties to treat COVID-19.   The research findings were published in the journal : Molecul...
Source: Tocilizumab or Actemra  Jun 18, 2020  1 year ago
Tocilizumab:  Pharma giant Roche’s rheumatoid arthritis drug, Actemra (Tocilizumab)  failed to help COVID-19 patients in Italian study according to the clinical trial findings released today.   The drug failed to help patients with early-stage COVID-19 pneumonia in an Italian study, the latest instance in another an anti-inflammatory drug has fallen through in a coronavirus ...
Source: WHO  Jun 18, 2020  1 year ago
WHO: The World Health Organization finally decided Wednesday to halt all trials of hydroxychloroquine as a potential treatment for hospitalized COVID-19 patients, finding it did not reduce the mortality rate.   The malaria and rheumatoid arthritis drug, hydroxychloroquine has been at the center of political and scientific controversy.   It has been touted as a possible treatment for th...
Source: Remdesivir and COVID-19  Jun 16, 2020  1 year ago
Remdesivir:  The American Food and Drug Administration has issued a warning to doctors and all healthcare professionals about a newly discovered potential drug interaction related to the investigational antiviral drug remdesivir, an antiviral drug that is being evaluated as a potential treatment for the novel coronavirus disease 2019 (COVID-19) and has also been granted emergency use authoriz...
Source: Hydroxychloroquine And Chloroquine  Jun 16, 2020  1 year ago
Hydroxychloroquine:  U.S. regulators  finally on Monday revoked emergency authorization for malaria drugs hydroxychloroquine and chloroquine promoted by scammers for treating COVID-19 amid evidence these drugs do not work and are in fact lethal in certain cases and causes serious side effects.   Strangely the official revocation of the drug to treat COVID-19 was done on a very low...
Source: COVID-19 Antibodies  Jun 16, 2020  1 year ago
COVID-19 Antibodies:  A team led by Scripps Research including scientists from University of California-SanDiego, University Of Washington, Harvard University and International AIDS Vaccine Initiative (IAVI)-New York has discovered a type of antibodies in the blood of recovered COVID-19 patients that provide powerful protection against SARS-CoV-2 coronavirus when tested in animals and human c...
Source: COVID-19 Research  Jun 16, 2020  1 year ago
COVID-19 Research: A new research led by Norwegian University of Science and Technology involving both Norwegian and Estonian researchers have established a cell culture that allows them to test antibody-laden plasma, drugs and drug combinations in the laboratory. The team also identified six potential antiviral candidates out of a base of 136 already approved drugs that could be repurposed. One c...
Source: COVID-19 Convalescent Plasma and Hyperimmune Plasma Or H-Ig Therapies  Jun 15, 2020  1 year ago
Convalescent Plasma: In an attempt to treat COVID-19, there have been numerous studies and trials to treat COVID-19 involving convalescent plasma transfusions but most have produced only mediocre results. Biotech companies working in the plasma space are now collaborating to develop a hyperimmune Ig therapy which could product produce better results.   Typically, plasma is the liquid compon...
Source: Niclosamide & COVID-19  Jun 13, 2020  1 year ago
Niclosamide & COVID-19: In a few preprint studies involving computational drug repurposing studies, niclosamide, an approved parasiticide drug was identified as a potential candidate. https://aac.asm.org/content/early/2020/04/28/AAC.00819-20   Past studies had also showed that it did have efficacy against the SARS-CoV-2 coronavirus in vitro studies and also another study published in Sc...
Source: COVID-19 Drugs and Ivermectin  Jun 10, 2020  1 year ago
COVID-19 Drugs: Medical Researchers from Broward Health Medical Center-South Florida, Drexel University College of Medicine and Florida International University have demonstrated that Ivermectin reduces mortality rates in hospitalized COVID-19 patients according to a cohort clinical study conducted. https://www.medrxiv.org/content/10.1101/2020.06.06.20124461v1.full.pdf+html   The study findin...
Source: COVID-19 Research  Jun 08, 2020  1 year ago
COVID-19 Research: Medical researchers from Columbia University Irving Medical Center have found in a recent research study that lowering the hormone testosterone in infected patients could lessen the severity of COVID-19 disease by preventing the new SARS-CoV-2 coronavirus from entering lung cells.   The research findings which are published as a preprint have yet to have been peer reviewe...
Source: COVID-19 Treatments  Jun 06, 2020  1 year ago
COVID-19 Treatments: Significant early data from a clinical study suggest that blocking the Bruton tyrosine kinase (BTK) protein provided clinical benefit to a group of patients with severe COVID-19. The medical researchers observed that the off-label use of the cancer drug acalabrutinib, a BTK inhibitor that is approved to treat several blood cancers, was associated with reduced respiratory distr...
Source: Famotidine And COVID-19  Jun 05, 2020  1 year ago
Famotidine and COVID-19: To date there are still no proven effective and approved drugs for COVID-19 and most drugs are only authorized under experimental use.   However a commonly available and inexpensive drug that is used to ease the symptoms of indigestion may prove a worthy contender for treating COVID-19 infection in those whose disease doesn't require admission to hospital.  ...
Source: Hydroxychloroquine  Jun 04, 2020  1 year ago
Hydroxychloroquine :The drug that has used to treat malaria and has been publicly touted by some as drug that can be used as a prophylaxis to prevent getting infected with COVID-19,  has in a rigorous a detailed study been proven to be ineffective. The research by medical experts from the University Of Minnesota is the first large, high-quality study to test the drug effectiveness in health w...
Source: Antibiotics  Jun 03, 2020  1 year ago
Antibiotics: Researchers from University of Melbourne are exploring ways to eradicate lethal pathogens with 'resistance resistant' antibiotics, and it could also contribute in the fight against SARS-CoV-2coronavirus disease or COVID-19 complications.   Typically as bacteria evolve, they develop strategies that undermine antibiotics and morph into 'superbugs' that c...
Source: COVID-19 Research  May 29, 2020  1 year ago
COVID-19 Research: A new research by University Of Massachusetts Medical School lead by Dr Sean P Ryder, a Professor Biochemistry and Molecular Pharmacology has demonstrated that there are numerous emerging genomic variants of the SARS-CoV-2 coronavirus and that some of these with changes on certain of parts of the structure of the genome, he warns could lead to drug resistance.   Dr Ryder ...
Source: COVID-19  May 28, 2020  1 year ago
COVID-19: Medical researchers and respiratory experts from the University of São Paulo's Medical School say that blood clotting disorders may explain some of the worst symptoms of COVID-19, including respiratory failure and pulmonary fibrosis and that the focus should be on treating COVID-19 as a thrombotic disease caused by a virus. Their research findings and reports were published...
Source: COVID-19 Drugs  May 28, 2020  1 year ago
COVID-19 Drugs: Spanish researchers from the Rovira i Virgili University Department of Cheminformatics and Nutrition have identified that the anti-inflammatory drugs carprofen and celecoxib could have antiviral properties against the SARS-CoV-2 coronavirus that causes the deadly COVID-19 disease, by inhibiting replication of the virus.   The research study has been published by the Int...
Source: Covid-19 Research  May 26, 2020  1 year ago
COVID-19 Research:  Medical researchers from Boston Children's Hospital have discovered that disulfiram, a US FDA-approved drug commonly used for treating alcoholism, blocks a key gatekeeper protein involved in inflammation, hence effectively inhibiting the inflammation process.   Typically, inflammation is the alarm system by which cells first respond to potential danger. But in e...
Source: COVID-19 Treatments  May 24, 2020  1 year ago
COVID-19 Treatment: To date there are still no proven effective drugs or antivirals to treat COVID-19 or some of its accompanying  symptoms such as the cytokine storms, blood clotting issues and the damage to epithelial cells etc. sweet wormwood or Artemisia annua. The public and medical community has been flooded with lots of misinformation that has been orchestrated by governments a...
Source: COVID-19 Drugs  May 20, 2020  1 year ago
COVID-19 Drugs:  According to medical researchers from Johns Hopkins Kimmel Cancer Center, the high blood pressure drug Prazosin if given early enough, could potentially reduce the risk of death from the cytokine storms that arise as a complication of COVID-19 disease.   The blood pressure drug Prazosin, is an US FDA a U.S. Food-approved alpha blocker that relaxes blood vessels, a...
Source: COVID-19 Supplements  May 13, 2020  1 year ago
COVID-19 Supplements:  Medical researchers from the Harvard Medical School, University of California-Davis, Virginia Commonwealth University and Institute for Systems Biology, Seattle have discovered that chemical molecules called resolvins which are a type of novel endogenous specialized pro-resolving lipid autacoid mediators (SPMs) could help prevent the cytokine storms caused by the COVID-...
Source: COVID-10 Therapeutics  May 11, 2020  1 year ago
COVID-19 Therapeutics:  In many drug repurposing and potential therapeutics studies, researchers first use computational screening platforms that involves models of the SARS-CoV-2 coronavirus in detail especially the binding sites of the spike proteins and to match molecular models of existing drugs, supplements, phytochemicals etc to see which have a greater affinity to bind to these sites, ...
Source: COVID-19 Drugs  May 11, 2020  1 year ago
COVID-19 Drugs: A research study by Columbia University, Northwell Health and Massachusetts General Hospital shows that Famotidine, a common heartburn drug improved the clinical outcomes of hospitalized COVID-19 patients.   The study involving 1620 patients from more than 10 hospitals in the United States showed that Famotidine associated with reduced risk of intubation or death in hospitaliz...
COVID-19 Supplements  May 10, 2020  1 year ago
COVID-19 Supplements: There are many who have always skeptical of the benefits of dietary supplements and nutraceuticals. While there has been many over blown claims by the unscrupulous, there are also many medical benefits that are often not extolled because of intense lobbying by the big pharmaceutical companies that have government and health authorities in their pockets along with greedy and u...
Source: COVID-19 Research  May 04, 2020  1 year ago
COVID-19 Research: Glycosaminoglycans are a class of polydisperse and heterogeneous natural occurring products currently used as pharmaceuticals and even in nutritional supplements. Included among them are unfractionated heparin, low molecular weight heparins, and heparinoids, all of which are clinically approved as anticoagulants with excellent bioavailability, stability, and safety pharmacokin...
Source: COVID-19 Drugs  Apr 30, 2020  1 year ago
COVID-19 Drugs: A study released by medical and drug researchers from the  Laboratory of Vector-Borne Viral Diseases and Center for Biologics Evaluation, U.S. Food and Drug Administration, Maryland, has concluded that most of the antivirals used as experimental drugs in the last four months basically had no effect on treating COVID-19. https://www.biorxiv.org/content/10.1101/2020.04.29.067983...
Source: COVID-19 Drugs  Apr 25, 2020  2 years ago
COVID-19 Drugs: The US FDA finally on Friday warned doctors against prescribing a malaria drug touted by President Donald Trump for treating COVID-19.   A medical alert sent by the regulators flagged reports of sometimes fatal heart side effects among coronavirus patients taking hydroxychloroquine or the related drug chloroquine. The decades-old drugs, also prescribed fo...
Source: COVID-19 Drugs  Apr 24, 2020  2 years ago
COVID-19 Drugs: Media reports are emerging everywhere that not only has Gilead’s Remidesivir Clinical Trial in China failed but also there could be the possibility of a cover-up and future data being manipulated as a result of the Giant Pharma company’s extensive financial resources.   Reports are emerging that the experimental antiviral drug Remdesivir has failed in its first r...
Source: COVID-19 Drug Research  Apr 21, 2020  2 years ago
COVID-19 Drug Research: A recent randomized, controlled study on the safety and efficacy of either lopinavir/ritonavir (LPV/r) or Arbidol, both antivirals that are used in some countries against HIV-1 and to treat influenza and respectively as treatments for COVID-19, the disease caused by the novel coronavirus SARS-CoV-2, suggests that neither drug improves the clinical outcome of patients hospit...
Source: COVID-19 Drugs  Apr 20, 2020  2 years ago
COVID-19 Drugs: Favipiravir or Avigan the flu drug that was developed by Toyama Chemicals in Japan that has since been acquired by Fuji Films Pharmaceuticals has been touted by many countries as an experimental drug for treating COVID-19 despite weak studies supporting its efficacy. It was brought to media attention by China advocating its use in one of its national health guidelines based on r...
Source: COVID-19 Drug Research  Apr 19, 2020  2 years ago
COVID-19 Drug Research: A new meta-analysis collaborative study by medical researchers from the University of San Diego and  Yantai Yuhuangding Hospital in Shandong and also Shengjing Hospital in Shenyang, both in China, has confirmed that both Chloroquine and Hydroxychloroquine are both not effective for treating the COVID-19 disease and in fact caused a variety of adverse events in most pat...
Source: COVID-19 Drugs  Apr 19, 2020  2 years ago
COVID-19 Drugs: According to sources, a French research entity is planning  to start a clinical trial on Ivermectin to treat COVID-19 disease soon. A lot of medical professionals are now coming out in support of using Ivermectin as a experimental drug while the many clinical trials are underway may pave the path for its official repurposing as a COVID-19 drug.     The interest sta...
Source: COVID-19 Drugs  Apr 18, 2020  2 years ago
COVID-19 Drugs: An abstract study submitted by researchers from University Of Utah, Harvard Medical School and Surgisphere Corporation showed that COVID-19 patients who were critically ill with lung injury needing mechanical ventilation, benefitted from taking Ivermectin compared to other drug alternatives. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3570270   The study lead by Dr A...
Source: COVID-19 DRUGS  Apr 18, 2020  2 years ago
COVID-19 Drugs: Ivermectin is gaining more attention as a possible drug candidate as it is an already approved drug for the treatment of parasites and also various virus causing diseases. It has already demonstrated to possess relevant antiviral properties.   More than 2.5 billion doses of the drugs have been used by humans in the last 30 years to treat malaria, dengue fever and even the &n...

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