mRNA Technology For Vaccines Questionable! Emory University Finds mRNA Vaccines Unable To Induce SARS-CoV-2 Bone Marrow Long-Lived Plasma Cells
Nikhil Prasad Fact checked by:Thailand Medical News Team Mar 14, 2024 1 month, 1 week, 6 days, 5 hours, 55 minutes ago
COVID-19 News: Since the emergence of the COVID-19 pandemic, vaccines have been claimed as a pivotal tool in mitigating the spread of the virus and reducing the severity of illness. Among the various vaccine platforms developed, mRNA vaccines have garnered significant attention for their so-called innovative technology and rapid deployment though the technology has been understudied!
Emory University Finds mRNA Vaccines Unable To Induce
SARS-CoV-2 Bone Marrow Long-Lived Plasma Cells
However, four years into the COVID-19 pandemic, we are learning that the vaccine so far has not stopped the transmission of the virus nor prevents anyone from getting infected. Rather, those that are controlling the COVID-19 narratives are now claiming that the COVID-19 vaccines prevent risk of disease severity and reduces risk of mortality…something that cannot be properly and accurately audited as figures can be easily manipulated.
Worryingly, more and more studies and case reports are emerging on the adverse effects of these vaccines especially the mRNa vaccines.
Thailand Medical News had covered on some of the these in our previous
COVID-19 News articles:
https://www.thailandmedical.news/news/italian-and-swiss-researchers-warn-that-covid-19-mrna-vaccines-can-lead-to-arrhythmias
https://www.thailandmedical.news/news/breaking-covid-19-vaccines-cause-elevated-levels-of-the-cancer-biomarker-ca-19-9-and-is-possibly-triggering-autoimmune-pancreatitis
https://www.thailandmedical.news/news/various-peer-reviewed-published-studies-and-case-reports-show-that-mrna-covid-19-vaccines-can-cause-lymphoma
https://www.thailandmedical.news/news/largest-vaccine-study-by-research-arm-of-the-world-health-organization-finds-a-variety-of-post-vaccine-medical-conditions
https://www.thailandmedical.news/news/covid-19-mrna-jabs-can-cause-new-onset-of-acute-interstitial-nephritis
https://www.thailandmedical.news/news/researchers-warn-that-covid-19-jabs-can-cause-centr
al-nervous-system-inflammatory-demyelinating-diseases
https://www.thailandmedical.news/news/breaking-international-study-warns-that-pfizer-s-mrna-vaccines-could-be-causing-a-silent-pandemic-of-liver-injury
https://www.thailandmedical.news/news/contrary-to-claims-that-covid-19-mrna-jabs-protect-the-vulnerable-cedars-sinai-study-finds-that-they-trigger-pots-in-many-with-underlying-conditions
https://www.thailandmedical.news/news/texas-md-anderson-cancer-center-warns-that-covid-19-mrna-vaccines-elevate-pd-l1-levels-disrupting-lung-cancer-treatments-progressing-other-cancers
https://www.thailandmedical.news/news/breaking-news-gene-study-reveals-how-covid-19-mrna-vaccine-leads-to-high-risk-of-iga-nephropathy-eventual-kidney-failure-and-possible-cancers
https://www.thailandmedical.news/news/covid-19-news-doctors-report-rare-incidence-of-pilomatricoma-or-benign-skin-tumor-developing-at-site-of-pfizer-s-mrna-vaccine-injection
https://www.thailandmedical.news/news/covid-19-mrna-jabs-can-cause-an-array-of-rare-pituitary-disorders-including-hypophysitis,-pituitary-apoplexy-and-even-enlarge-pituitary-adenomas
https://www.thailandmedical.news/news/post-covid-19-vaccination-emergence-of-kaposi-sarcoma-in-immunocompetent-individuals
https://www.thailandmedical.news/news/covid-19-mrna-jabs-can-trigger-new-onset-of-systemic-lupus-erythematosus
However, recent research conducted at Emory University in Georgia, USA, has raised questions about the long-term efficacy of mRNA vaccines in inducing durable immunity against SARS-CoV-2, the virus responsible for COVID-19.
Understanding Long-Term Immunity: The Importance of Long-Lived Plasma Cells (LLPCs)
At the heart of effective vaccination lies the generation of long-lived plasma cells (LLPCs), specialized immune cells capable of producing antibodies that provide enduring protection against pathogens. Traditionally, natural infections and conventional vaccines, such as those for influenza and tetanus, have been shown to induce LLPCs in the bone marrow, ensuring sustained immunity for decades.
However, the Emory University study sheds light on a notable discrepancy in the immune response elicited by mRNA vaccines for SARS-CoV-2.
Investigating mRNA Vaccine Efficacy: Emory University's Research Findings
The study, led by researchers at Emory University, enrolled 19 healthy adults who had received mRNA vaccines against SARS-CoV-2. Bone marrow aspirates were collected from participants at various intervals post-vaccination, ranging from 1.5 to 33 months. Through meticulous analysis, the researchers sought to examine the presence and distribution of SARS-CoV-2-specific antibody-secreting cells (ASCs) within the bone marrow compartments.
Surprising Discoveries: Exclusion of SARS-CoV-2-Specific ASCs from the LLPC Compartment
The findings of the study revealed a striking pattern: while influenza- and tetanus-specific ASCs were readily detected in the LLPC subset of the bone marrow, SARS-CoV-2-specific ASCs were predominantly excluded from this compartment. Despite the presence of SARS-CoV-2-specific ASCs in other subsets of the bone marrow, their exclusion from the LLPC compartment posed a significant challenge to the longevity of claimed immune protection conferred by mRNA vaccines.
Implications for Vaccine Development: Addressing the Limitations
The implications of these findings are profound, suggesting inherent limitations in the ability of current mRNA vaccine platforms to induce robust LLPC responses essential for long-term immunity. To overcome these limitations, researchers may need to explore novel approaches, such as optimizing vaccine regimens, engineering spike proteins to enhance immunogenicity, or developing vaccine adjuvants to promote LLPC formation.
Unraveling the Mechanisms: Insights into LLPC Maturation and Migration
Further research is warranted to unravel the intricate molecular mechanisms underlying the inability of mRNA vaccines to effectively induce LLPCs. Understanding the processes involved in LLPC maturation and migration to the bone marrow microenvironment is critical for informing the development of next-generation vaccines that can confer durable immunity against SARS-CoV-2 and other viral pathogens.
Impacts on Public Health Policy: Navigating Vaccine Distribution Strategies
The Emory University study underscores the importance of continued surveillance and evaluation of vaccine efficacy beyond the initial phase of immunization. Policymakers and public health officials must consider these findings when formulating vaccine distribution strategies and recommending booster doses to ensure sustained protection against COVID-19.
The plans by many pharmaceutical companies and health authorities to deploy mRNA technology into the development of vaccines for other pathogenic diseases and even cancer should be reconsidered as more studies are needed to assess the mechanisms of these mRNA vaccines and their efficacy and also their adverse effects.
Conclusion: A Call for Continued Research and Innovation in Vaccine Development
In conclusion, Emory University's research offers valuable insights into the challenges of achieving long-term immunity against SARS-CoV-2 with current mRNA vaccine technologies. By identifying the limitations in LLPC induction, scientists are better equipped to devise strategies for enhancing vaccine efficacy and durability. As the global community continues to confront the COVID-19 pandemic, ongoing research and innovation in vaccine development remain paramount in the fight against viral threats.
The study findings were published on a preprint server and is currently being peer reviewed for publication into the peer reviewed journal: Nature.
https://www.researchsquare.com/article/rs-3979237/v1
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