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BREAKING NEWS
Nikhil Prasad  Fact checked by:Thailand Medical News Team Jan 05, 2024  1 month, 2 weeks, 5 days, 10 hours, 35 minutes ago

BREAKING COVID-19 News! Potentially Even More Immune Evasive And Virulent Spawns Of JN.1 Discovered In India! Expect More Such Strains From India!

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BREAKING COVID-19 News! Potentially Even More Immune Evasive And Virulent Spawns Of JN.1 Discovered In India! Expect More Such Strains From India!
Nikhil Prasad  Fact checked by:Thailand Medical News Team Jan 05, 2024  1 month, 2 weeks, 5 days, 10 hours, 35 minutes ago
COVID-19 News: Researchers and variant hunters around the world are carefully monitoring the COVID-19 situation in India, the land that gave us the Delta variant after a new worrisome JN.1 spawn spotting an extremely high number of mutations was detected.


JN.1-Slipper With Spike L455S, F456L, V1104L NSP3 T1465I G17334T
I am calling it the Singh variant after the Punjabis who had ripped me off!
Image credit: Rodrigo de Matos - remodified

 
A Chinese scientist cum variant hunter from the Dept of Computer Science, Tsinghua University-China was the first to identify this worrisome sub-lineage from sequences uploaded to GISAID platform about 38 hours ago.
 
https://github.com/sars-cov-2-variants/lineage-proposals/issues/1253
(Look under branch 4)
 
This worrisome sub-lineage contained multiple mutations that are concerned with immune evasion including the spike mutations L455S, F456L, V1104L and the NSP3 mutations T1465I G17334T
 
It also contained the Orf1a:T2283I mutation and also the mutations C7113T,T22928C,T3565C
 
Some of the other mutations are possibly linked with enhanced pathogenesis and increased virulence.
 
The initial sequences were from Bengaluru, Karnataka-India and from Pune, Maharashtra-India:
 
-India/KA-RFNB-20224/2023 Col 12/2023 Bengaluru Karnataka India
-India/KA-RFNB-20370/2023 Col 12/2023 Bengaluru Karnataka India
-India/MH_BJCOG_INSACOG_6141/2023 Col 12/25/2023 Pune Maharashtra India
 
All were from hospitalized patients.
 
Another, researcher who has been monitoring the upload of sequences on GISAID had also confirmed the presence of these new worrisome sub-lineages.
https://twitter.com/HNimanFC/status/1743005338356384068
As of today, a total of 11 such sequences have been identified, all originating form India.
 
Scientists are monitoring to see if this variant had the relevant viral fitness to become predominant in circulation.
https://github.com/sars-cov-2-variants/lineage-proposals/issues/1262
 
Meanwhile the emergence of such a variant has also cause alarms among many as India which has a reputation of concealing and lying about the true COVID-19 situation in the country could actually be providing the “playground” for the JN.1 to evolve and spawn some dangerous variants as it has a large population with varying degrees of immunity and also many immunocompromised individuals and individuals who are also carrying other pathogens or disease and are not even aware of their health status!
es-reported-for-friday">https://www.thailandmedical.news/news/covid-19-news-india-continues-to-conceal-and-lie-about-actual-covid-19-situation-including-death-figures-mere-640-new-cases-reported-for-friday
 
https://www.thailandmedical.news/news/covid-19-news-all-covid-19-data-from-india-probably-fake-india-does-not-report-jn-1-but-airport-surveillance-in-singapore-shows-many-indians-with-jn-1
(Note that it was only after this coverage that India 18 hours later admitted that they had the JN.1 variant!)
 
Most of the COVID-19 News coverages originating from India at the moment are not the least reliable as all the COVID-19 figures quoted cannot the least be trusted. Social media post from ordinary Indian citizens are showing that the situation is far worse that what is being reported especially people seriously sick with severe pneumonia!
 
Thailand Medical News will be providing more updates on this identified sub-lineage and also other emerging sub-lineages until the garbage Western media starts coming onboard and covering it as they did in the case of the BA.2,86 variant and taking all credit for it. We were the first to write about the BA.2.8 variant on the morning of the 15th Of August 2023 even before it was designated as BA.2.86!
https://www.thailandmedical.news/news/breaking-news-researchers-worried-about-new-sars-cov-2-variant-first-identified-in-israel-and-now-in-denmark-that-could-be-called-the-ba-x-variant
 
Hopefully, in a few months’ time, the more lethal SARS-CoV-2 variants would emerge and help wipe out all the critics, competitors and bullies of Thailand Medical News!
 
For the latest COVID-19 News, keep on logging to Thailand Medical News.

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