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A section specially dedicated to Long COVID or PASC ie Post-acute Sequelae of COVID-19. The section on Long COVID will cover all the latest research and developments about Long COVID or PASC and also provide guidelines to all long haulers about the new treatment protocols and therapeutics available for long COVID or Post-acute Sequelae of COVID-19 (PASC). Long COVID is expected to become a major h...
A new study has revealed how the COVID-19 pandemic may have reshaped the circumstances surrounding Clostridioides difficile infection (CDI), a potentially dangerous intestinal infection commonly affecting hospitalized patients.
Researchers found that COVID-19 reshaped medication exposures and infection patterns surrounding C. difficile,
without independently increasing 90-day mortality.
I...
Scientists are gaining a clearer picture of why the brain and central nervous system deteriorate in conditions ranging from stroke and Parkinson’s disease to Alzheimer’s disease and traumatic brain injury. At the same time, researchers are uncovering biological processes that could potentially help damaged nervous tissue recover.
New neuroscience findings reveal how inflammation, ...
Scientists investigating why some Long COVID patients suffer debilitating crashes after even modest activity may have a new biological explanation. A newly proposed theory suggests that the problem could involve mitophagy, the cellular process responsible for removing damaged mitochondria, and an inability of cells to complete this essential cleanup efficiently.
Researchers propose that faile...
Researchers have developed an unusual quantum-assisted method that may help identify subtle balance-control abnormalities in some people after COVID-19, including changes that could be difficult to detect during ordinary clinical examinations.
Quantum-assisted analysis identified a small subgroup of post-COVID participants showing distinctive abnormal-like
patterns in balance and postural co...
Five years after COVID-19 first disrupted the world, its effects on human longevity appear far more persistent than a temporary pandemic shock. A major international analysis of 34 high-income countries found that life expectancy in 31 countries remained below expected levels in 2024.
Life expectancy remains below expected levels across most wealthy nations five years after the COVID-19 pande...
A treatment designed to remove potentially harmful antibodies from the blood can dramatically lower these antibodies in people with Long COVID, but the biological change does not appear to translate into meaningful improvements in physical performance, according to a new prospective exploratory study.
Blood-filtering immunoadsorption sharply reduced suspected Long COVID autoantibodies but failed...
More than six years after SARS-CoV-2 first emerged, scientists are warning that COVID-19 can leave behind complicated health problems affecting far more than the lungs. A major collection of research on long COVID highlights persistent inflammation, neurological symptoms, fatigue, metabolic changes and possible effects on other chronic diseases.
New research reveals how long COVID may drive l...
MRI Study Finds Brain Changes After COVID-19
A new brain imaging study suggests COVID-19 may be associated with measurable reductions in two important structures: the olfactory bulbs, which process smell, and the hippocampus, which is central to memory and learning.
MRI research links COVID-19 with smaller smell-processing and memory-related brain regions, especially among
patients reporting sme...
A new study from China has found that people who were previously healthy can experience measurable reductions in heart, lung and exercise performance months after SARS-CoV-2 infection, adding to concerns that Long COVID can affect several body systems at the same time.
Long COVID patients showed measurable reductions in exercise capacity, cardiovascular performance and breathing
function mon...
COVID-19 may leave consequences that extend far beyond the lungs, with researchers warning that SARS-CoV-2 infection could disturb bone health from microscopic bone cells all the way to the overall strength of the skeleton. The new scientific review brings together clinical findings, animal experiments, advanced imaging and biomechanical research suggesting that COVID-19-associated bone damage is ...
Researchers Find Measurable Changes in Long COVID Brains
Scientists have identified two unusual brainwave patterns that may help explain fatigue and “brain fog” in Long COVID. The findings raise the possibility that electroencephalography, or EEG, could help assess difficult-to-measure neurological symptoms.
Altered beta and alpha brainwaves were linked to brain fog and fatigue i...
A striking medical case involving a 55-year-old woman with COVID-19 myocarditis, severe heart dysfunction and worsening kidney injury suggests that COVID-19 may directly or indirectly create conditions capable of triggering a dangerous complication known as BRASH syndrome.
COVID-19-associated myocarditis and worsening kidney dysfunction may create conditions that help trigger
the potentially...
A new study has identified a troubling biological pathway that could explain why some people experience persistent joint, cartilage and bone problems after COVID-19. Researchers found that a small signaling peptide called endothelin-1 (ET-1) may help transmit damaging effects from SARS-CoV-2-injured lungs to distant skeletal tissues.
Researchers have identified endothelin-1 as a possible link...
Oxidative Damage May Persist Long After Infection
Scientists studying long COVID have found striking evidence that the body can remain under prolonged oxidative stress months, and sometimes years, after the original coronavirus infection.
Long COVID patients showed substantially greater oxidative damage together with weakened antioxidant
defenses, even many months after their initial infect...
Long COVID may affect more than the lungs, heart, brain and nervous system. A newly published case report suggests that problems involving the salivary glands and their drainage ducts can appear months after repeated SARS-CoV-2 infections, causing severe dry mouth, facial swelling and considerable pain.
An unusual case suggests long COVID may be linked to severe salivary duct enlargement, dry...
Severe cases and deaths climb sharply
Taiwan is facing a renewed COVID-19 surge, with health authorities reporting 72 new domestic severe cases and 14 deaths between August 4 and 10, marking a concerning acceleration in serious disease. The Taiwan Centers for Disease Control said severe cases increased from 62 during the preceding seven days, while deaths jumped from three to 14.
Taiwan’s ...
Long COVID remains a major medical challenge, particularly for patients affected by post-exertional malaise (PEM) and persistent cognitive problems commonly described as “brain fog.” These symptoms can interfere with employment, household activities, exercise and even relatively minor physical or mental tasks.
A new scientific review proposes investigating eight nutraceuticals tar...
A new study has uncovered distinctive changes in blood metabolism among people suffering from neuropsychiatric Long COVID, offering fresh clues as to why patients can experience persistent fatigue, low mood and cognitive difficulties months after their initial SARS-CoV-2 infection.
Researchers have identified distinctive metabolic changes linked to fatigue, depressive symptoms and brain struc...
A detailed investigation of intestinal tissue from people with Long COVID has uncovered signs of lingering SARS-CoV-2 alongside major disturbances in the gut’s immune defenses, potentially offering important clues about why symptoms can continue for years after the original infection.
Scientists find lingering SARS-CoV-2 signals and widespread immune disruption in colorectal tissue from...
Scientists have uncovered an unexpected way SARS-CoV-2 may activate one of the body’s important antiviral defenses. Rather than simply recognizing genetic material belonging to the virus, the immune sensor MDA5 appears able to detect disruptions that infection causes to the cell’s own RNA-processing system.
SARS-CoV-2 disrupts normal cellular RNA processing, producing abnormal hos...
A major systematic review involving data from tens of millions of people has found that COVID-19 infection is consistently associated with an increased risk of developing new autoimmune and autoinflammatory diseases. The findings suggest the effect can involve the joints, skin, blood vessels, thyroid, digestive system, blood and nervous system, although the absolute risk for any individual remains...
The neurological consequences of COVID-19 continue to attract intense scientific attention as researchers investigate why some patients develop persistent brain fog, fatigue, anxiety, sleep disturbances, autonomic problems, and other neurological or neuropsychiatric symptoms. One emerging area of interest involves oxytocin, a neuropeptide whose functions extend far beyond social bonding.
Emer...
A major multinational study has raised new concerns about the possible long-term effects of COVID-19, finding that people with existing thyroid disorders who had COVID-19 were more likely to later be diagnosed with thyroid cancer than comparable patients without a recorded SARS-CoV-2 infection.
A large multinational study found a higher long-term rate of thyroid cancer diagnosis following COV...
Scientists have uncovered a striking way in which a SARS-CoV-2 protein can interfere with the tiny energy-producing structures inside human cells. The study focused on ORF7a, an accessory protein made by the virus, and found that it can dramatically reprogram cellular metabolism while weakening mitochondrial energy production.
SARS-CoV-2 protein ORF7a can rewire cellular metabolism and disrup...
A new murine study has found that SARS-CoV-2 infection can intensify abnormalities involving dopamine, brain immune cells and nerve-cell degeneration in a mouse model of early Parkinson’s disease. The effects were particularly pronounced in male mice, while females showed considerably greater resistance to neurological damage.
Murine research shows SARS-CoV-2 can amplify dopamine disrup...
Doctors are drawing attention to a rare but potentially serious blood complication that can appear weeks or even months after SARS-CoV-2 infection. A newly published case and review suggest that COVID-19 may trigger pure red cell aplasia (PRCA), a disorder in which the bone marrow suddenly becomes unable to produce enough red blood cells.
Doctors report that SARS-CoV-2 may rarely trigger severe ...
Scientists have uncovered how a key SARS-CoV-2 enzyme can simultaneously weaken the body's early antiviral defenses and reorganize the metabolism of infected cells, creating conditions that help the coronavirus multiply.
The study focused on the viral papain-like protease, or PLpro, an enzyme contained within the SARS-CoV-2 Nsp3 protein. Researchers discovered that PLpro removes prote...
Scientists investigating why COVID-19 antibodies remain detectable longer in some people than others have found that a naturally occurring hormone may provide an important part of the answer. New research suggests that levels of 17β-estradiol, a form of estrogen found in both women and men, are strongly associated with how long antibodies against SARS-CoV-2 persist after infection. Researcher...
COVID-19 may have lasting effects on the body’s ability to control blood sugar, with growing evidence suggesting that SARS-CoV-2 can interfere with pancreatic beta cells, the specialized cells responsible for producing and releasing insulin. Researchers warn that these disturbances could help explain why some people develop abnormal blood sugar or newly diagnosed diabetes during or after COV...
People suffering from long COVID-related chronic fatigue may experience depression differently from those with typical depression, according to a new study by researchers from the University Hospital of Cagliari, the University of Cagliari, the Federico II University of Naples, the University of Kore, and the Federal University of Rio de Janeiro. Rather than feeling overwhelmingly sad, many patien...
Italian Study Reveals How Immune Overreaction and Iron Disruption May Drive Serious Illness and Long COVID
Researchers from IRCCS MultiMedica, Italy, and the Università degli Studi dell'Insubria, Varese, Italy, have uncovered compelling evidence that excessive inflammation and abnormal iron metabolism are closely linked to the severity of COVID-19. Their findings also suggest that thes...
Long COVID Recovery Remains Slow for Many
A major four-year study involving 3,590 people with long COVID has revealed that only about one in three patients achieved a satisfactory level of recovery, highlighting the lasting health burden caused by the condition. Researchers say fatigue, muscle pain and problems affecting the body's automatic functions were among the strongest warning signs th...
A new scientific review suggests that excessive inflammation may be the key reason why many people continue to struggle with Long COVID months after recovering from the initial infection. Rather than the virus itself, researchers believe an ongoing cycle of immune disruption and inflammation could explain why symptoms such as fatigue, brain fog, muscle pain, and exercise intolerance refuse to disa...
Researchers are proposing a new way of understanding why aging and long COVID may trigger persistent health problems, suggesting that dormant viruses hiding inside the body could become active again when the body's natural defense systems begin to weaken. The new review introduces an interconnected biological model that may explain why chronic inflammation, immune dysfunction, and viral reacti...
A growing body of research suggests that COVID-19 may temporarily weaken the immune system enough to allow the dormant varicella-zoster virus (VZV), the virus that causes chickenpox, to reactivate as shingles in some people. However, researchers stress that this does not mean COVID-19 directly causes shingles in everyone. Instead, it may reduce the body's immune reserve, making reactivation mo...
Researchers are warning that COVID-19 may have far-reaching effects beyond the lungs, heart, and immune system. A new scientific review suggests the virus may also trigger long-lasting damage to the skeleton, increasing the risk of weaker bones, fractures, and impaired bone repair, even after people appear to have recovered from the infection.
New research suggests COVID-19 may silently damag...
Researchers have uncovered compelling new evidence showing that small fragments of the SARS-CoV-2 spike protein can directly trigger spinal nociception, the nervous system process responsible for detecting and transmitting potentially harmful stimuli. The discovery provides a new explanation for why many people infected with COVID-19 experience severe body aches and persistent pain, and why some c...
A team of Italian researchers has identified what could become one of the most reliable molecular fingerprints of SARS-CoV-2 infection. By examining multiple human lung models, the scientists discovered that one tiny genetic regulator, known as miR-141-3p, was consistently suppressed after exposure to the virus, regardless of the type of respiratory cells studied. The findings may pave the way for...
Researchers Discover a Previously Overlooked Brain Region That Could Help Explain Tremors, Internal Vibrations and Neuromuscular Fatigue
A new brain imaging study has uncovered compelling evidence that a tiny but strategically important region deep within the brain—known by the researchers as the mammillary body-fornix gate—may play a central role in the neurological symptoms experien...
Severe COVID-19 infections may leave behind far more than protective antibodies. A new study suggests that antibodies produced during severe COVID-19 infections can actively reshape the immune system, promoting inflammatory responses, altering gene regulation, and increasing the likelihood of attacking the body's own proteins. In contrast, antibodies from moderate cases appear to trigger a mor...
Long COVID continues to leave millions of people battling symptoms long after their initial coronavirus infection has ended. Now, researchers in Italy have found that people suffering from a heavier burden of neurological and brain-related Long COVID symptoms are much more likely to experience difficulties in everyday life, from working and studying to maintaining relationships and managing routin...
For millions of people living with post-acute sequelae of SARS-CoV-2 (PASC), better known as long COVID, the search for effective treatments has been marked by uncertainty and frustration. Persistent symptoms such as crushing fatigue, memory impairment, poor concentration, dizziness, abnormal heart rate, digestive disturbances, and exercise intolerance often continue for months or even years after...
A small clinical trial has found that a handheld device designed to stimulate the vagus nerve may help ease some of the persistent symptoms experienced by people living with Long COVID. While the treatment is still experimental and larger studies are needed, researchers believe the approach could become an important option for a condition that currently has no approved therapies. The findings are ...
Study Finds Lasting Eye Changes in Recovered Patients
A new study from researchers at the Second Affiliated Hospital of Fujian Medical University in Quanzhou, China, has found that people who recovered from COVID-19 may continue to experience subtle but potentially important changes in the transparent front surface of the eye. The findings suggest that the virus could have longer-term effects on ...
Researchers Identify Genetic Differences That May Influence Blood Sugar Problems After COVID-19
A new study from researchers in Thailand has identified inherited variations in two immune-related genes that may influence whether some people develop high blood sugar after recovering from COVID-19.
The findings provide new insights into why metabolic complications differ among individuals following ...
Long COVID may not affect every brain in the same way
Long COVID has puzzled doctors for years because people with similar symptoms often show very different patterns of recovery. Now, researchers have found evidence that persistent cognitive problems after COVID-19 may actually fall into two separate brain-related subtypes, offering a possible explanation for why some patients experience more se...
For many people, recovering from COVID-19 does not mean the illness is truly over. A new study has found that people living with long COVID are more likely to experience slower thinking, poorer decision-making abilities, persistent mental fatigue, and ongoing memory complaints compared to those who recovered from COVID-19 or never had the infection.
The research was conducted by scientist...
Scientists Warn Long COVID Could Raise Future Dementia and Parkinson’s Risks
Millions of people have recovered from COVID-19, but growing evidence suggests that the virus may leave behind lasting effects on the brain. A new scientific review has highlighted how long COVID may trigger changes linked to memory loss, depression, anxiety, and even increase the risk of future neurodegenerative d...
Scientists identify a hidden chain reaction that blocks blood flow in the lungs and worsens COVID-19
A new study has uncovered an important mechanism behind the dangerous lung complications seen in severe COVID-19. Researchers have discovered that neutrophils, a type of white blood cell that normally helps fight infections, can become unusually sticky after SARS-CoV-2 infection. Instead of moving...
Alarming Rise in Rectal Cancer Among Younger Adults Sparks New Questions
Rectal cancer is emerging as one of the fastest-changing cancer trends in the United States, with health experts increasingly concerned that the disease is no longer confined to older populations. While established risk factors such as obesity, unhealthy diets, smoking, alcohol consumption, physical inactivity, inherited gen...
Thailand Medical News: The largest-ever clinical trial exploring how people with long COVID should be treated has found encouraging evidence that specialist multidisciplinary care can significantly reduce one of the condition's most disabling symptoms—persistent fatigue. Researchers say the findings provide some of the strongest evidence yet that dedicated long COVID clinics can improve ...
Medical News: Researchers are uncovering a hidden layer of biology that could explain why COVID-19 continues to damage the heart long after the initial infection has passed. A new scientific review suggests that tiny molecules known as non-coding RNAs (ncRNAs) may play a central role in triggering inflammation, blood clotting, heart muscle injury, and long-term cardiovascular complications followi...
Medical News: Researchers Find Immune Cells May Stay Overactive Long After COVID-19 Infection
Scientists have uncovered fresh evidence that may help explain why some people continue to suffer from long COVID months or even years after their initial infection. The new study found that a group of immune cells known as CD8+ T cells remain unusually aggressive in people with long COVID, continuing to...
Medical News: For many people, recovering from COVID-19 means the infection is over, but the journey back to full health may be far from complete. A new study from Iran has found that a large proportion of people who were hospitalized with COVID-19 continue to struggle with insomnia months after their recovery, and those persistent sleep problems are closely linked to depressive symptoms. The find...
Medical News: A major new systematic review has found growing evidence that COVID-19 infection may increase the risk of developing a wide range of autoimmune diseases long after the initial illness has passed. While the overall risk for any individual remains relatively low, researchers say the findings highlight the need for doctors to remain alert for new autoimmune conditions, especially in peo...
