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BREAKING NEWS
Source: Massachusetts Institute of Technology  Feb 08, 2019  5 years, 2 months, 1 week, 4 days, 14 hours, 16 minutes ago

Oral Insulin Capsule On The Horizon for patients with type 2 diabetes

Oral Insulin Capsule On The Horizon for patients with type 2 diabetes
Source: Massachusetts Institute of Technology  Feb 08, 2019  5 years, 2 months, 1 week, 4 days, 14 hours, 16 minutes ago

An MIT-led research team has developed a drug capsule that could be used to deliver oral doses of insulin, potentially replacing the injections that people with type 2 diabetes have to give themselves every day.

Oral Insulin Capsule
An MIT-led research team has developed a drug capsule that could
be used to deliver oral doses of insulin. Credit: Felice Frankel

About the size of a blueberry, the capsule contains a small needle made of compressed insulin, which is injected after the capsule reaches the stomach.  In tests in animals, the researchers showed that they could deliver enough insulin to lower blood sugar to levels comparable to those produced by injections given through skin. They also demonstrated that the device can be adapted to deliver other protein drugs.

"We are really hopeful that this new type of capsule could someday help diabetic patients and perhaps anyone who requires therapies that can now only be given by injection or infusion," says Robert Langer, the David H. Koch Institute Professor, a member of MIT's Koch Institute for Integrative Cancer Research, and one of the senior authors of the study in interview with Thailand Medical News.

Giovanni Traverso, an assistan