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Nikhil Prasad  Fact checked by:Thailand Medical News Team Jan 20, 2024  1 month, 4 days, 17 hours, 48 minutes ago

Medical News: Scientist Discover More Than 921 Carcinogenic Chemicals In Consumer Goods And In The Environment That Can Cause Breast Cancer!

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Medical News: Scientist Discover More Than 921 Carcinogenic Chemicals In Consumer Goods And In The Environment That Can Cause Breast Cancer!
Nikhil Prasad  Fact checked by:Thailand Medical News Team Jan 20, 2024  1 month, 4 days, 17 hours, 48 minutes ago
Medical News:  In an era marked by unprecedented technological advancements and industrial growth, the pervasive presence of synthetic chemicals has become an integral part of our daily lives. Unfortunately, a significant downside to this progress is the potential health hazards associated with exposure to various chemical compounds. A study conducted by the Silent Spring Institute in Massachusetts, USA, has unveiled a disconcerting revelation - more than 921 potentially carcinogenic chemicals are prevalent in consumer goods and the environment, posing a substantial risk of breast cancer. This Medical News report delves into the details of this research, shedding light on the urgency of reevaluating our approach to chemical safety.


921 Chemicals Found In Consumers Goods And In The
Environment That Causes Breast Cancer


The Rising Threat of Breast Cancer
Breast cancer has emerged as a significant public health concern, currently ranking as the most commonly diagnosed cancer in the United States. The alarming surge in breast cancer rates, particularly among young women, is a trend that genetics alone cannot explain. This underscores the necessity for a deeper understanding of the environmental factors contributing to this concerning uptick. Dr Jennifer Kay, a research scientist at Silent Spring Institute and the lead author of the study, emphasizes the urgency of developing innovative tools to identify and mitigate environmental risks associated with breast cancer.
 
Identifying Potential Breast Carcinogens
To embark on this crucial mission, researchers at Silent Spring Institute meticulously sifted through international and U.S. government databases. These databases, including those from the International Agency for Cancer Research, the National Toxicology Program, the U.S. Environmental Protection Agency, and the National Cancer Institute, served as valuable repositories of information on chemicals that induce mammary tumors in animals and those acting as endocrine disruptors, capable of altering hormonal signals linked to breast cancer.
 
A Disturbing Tally
The outcome of this exhaustive research is a staggering total of 921 chemicals that exhibit the potential to contribute to the development of breast cancer. What adds to the gravity of this discovery is the realization that 90% of these chemicals are ubiquitous in consumer products, food and drink, pesticides, medications, and workplaces. Breaking down this extensive list, researchers identified 278 chemicals that cause mammary tumors in animals, with over half inducing increased estrogen or progesterone production and approximately a third activating the estrogen receptor. Dr Kay accentuates the concerning correlation between breast cancer and hormonal alterations, as breast cancer is fundamentally characterized as a hormonal disease.
 
DNA Damage and Hormone Disruption
In recognition of the fact that DNA damage can serve as a trigger for cancer, researchers delved deeper into databases, identifying 420 chemicals on their list that possess the dual traits of damaging DNA and disrupting hormo nes. This dual characteristic raises significant concerns about the potential risks associated with these chemicals, suggesting that they may be more hazardous. Moreover, the study indicates that chemicals causing mammary tumors in animals are more likely to exhibit both DNA-damaging and hormone-disrupting traits than those that do not.
 
Shifting Paradigms in Chemical Safety Assessment
Historically, predicting the potential of a chemical to cause breast cancer has been heavily reliant on expensive and time-consuming animal studies. However, this study introduces a paradigm shift by suggesting that screening chemicals for specific hormonal traits could be an efficient and effective strategy to identify potential breast carcinogens. This approach not only streamlines the identification process but also aligns with modern efforts to incorporate mechanistic information into chemical safety assessments, marking a significant step towards more targeted and humane testing methods.
 
Implications for Regulatory Agencies
The study's findings have far-reaching implications for regulatory agencies, with a particular focus on the U.S. Environmental Protection Agency (EPA). Notably, the list of identified chemicals includes over 30 pesticides that had previously received EPA approval despite evidence linking them to mammary tumors. The researchers express hope that their comprehensive list, encompassing hundreds of endocrine disruptors, will contribute to the EPA's strategic plan for evaluating pesticides' effects on hormones. Such measures are crucial to safeguard public health and mitigate the potential risks associated with these chemicals.
 
Application of the Key Characteristics Framework
Integral to the study's approach is the utilization of the Key Characteristics (KCs) framework, a systematic methodology developed by the International Agency for Research on Cancer (IARC). This framework focuses on key traits, such as genotoxicity, altered cellular signaling, increased cell proliferation, immunosuppression, inflammation, and epigenetic modifications, to identify potential carcinogens based on shared biological effects. By applying the KCs framework, the study aims to enhance hazard identification, improve chemical testing methodologies, and advance breast cancer prevention.
 
Understanding the Mechanisms
Genotoxicity, a key characteristic of most known carcinogens, emerged as prevalent among the breast cancer-relevant chemicals identified in the study. Additionally, the study underscores the significance of "receptor-mediated effects," particularly through estrogen and progesterone signaling pathways, as a crucial key characteristic for breast cancer. The combination of genotoxicity and endocrine activity surfaced as a common feature among mammary carcinogens, further reinforcing the intricate link between DNA damage and hormonal disruptions in the development of breast cancer.
 
A Comprehensive List for Risk Assessment
The updated list of 921 breast cancer-relevant exposures, combining 279 rodent mammary carcinogens with 642 additional chemicals exhibiting mechanistic evidence, provides a comprehensive understanding of potential risks. This list, classified based on their ability to induce hormone synthesis, activate estrogen receptors, and cause DNA damage, establishes a robust foundation for more informed hazard assessment and risk reduction.
 
Future Directions and Recommendations
Looking ahead, the study suggests prioritizing further research and precautionary regulation for the most potent chemicals identified in the list. The integration of genotoxicity and endocrine activity data could serve as a predictive tool for identifying potential breast carcinogens. The study calls for strengthened testing of chemicals, improved hazard identification methods, and a more comprehensive approach to chemical testing to better understand breast cancer etiology and enhance prevention strategies.

Conclusion
In conclusion, the Silent Spring Institute's groundbreaking study unravels the complexity surrounding more than 921 potentially carcinogenic chemicals in consumer goods and the environment, posing a significant risk of breast cancer. The application of the Key Characteristics framework provides a systematic approach to identifying these chemicals based on shared biological effects. The findings emphasize the urgency of reevaluating our approach to chemical safety assessment, urging regulators and manufacturers to adopt more efficient screening methods to protect public health. The comprehensive list of breast cancer-relevant exposures serves as a valuable resource for future research, biomonitoring, and epidemiological studies, aiming to improve our understanding of breast cancer etiology and enhance prevention strategies. As we navigate the intricate web of chemical exposures, this study propels us towards a more informed and proactive stance in addressing one of the leading causes of cancer death among women worldwide.
 
The study findings were published in the peer reviewed journal: Environmental Health Perspectives.
https://ehp.niehs.nih.gov/doi/10.1289/EHP13233
 
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The list of 921 carcinogenic chemicals are listed below:
 
Styrene
4,4'-Methylenebis(2-chloroaniline)
4-Hydroxyaminoquinoline 1-oxide hydrochloride
Tribenuron-methyl
2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine
1-Amyl-1-nitrosourea
1,4-Benzenediamine
Glycidyl methacrylate
1,2-Dibromoethane
1,3-Butadiene
1,2-Dichloroethane
Acrylonitrile
1-Ethylnitroso-3-(2-oxopropyl)urea
Aroclor 1254
1,3-Propane sultone
Estradiol dipropionate
N-Formyl-N-hydroxy-4-aminostilbene, (E)-
N-Hydroxy-N-propionyl-trans-4-aminostilbene
C.I. Disperse Black 6
3,3'-Dimethylbenzidine
2,4-Dinitrotoluene
2-Amino-5-nitrothiazole
Malathion
Simazine
1,2-Diphenylhydrazine
1,4-Dioxane
Griseofulvin
Chloroprene
Tetrachloroethylene
Technical chlordane
Leucomalachite green
anti-Benzo(a)chrysene-11,12-diol-13,14-epoxide
Folpet
Benz(a)anthracene-7-carboxaldehyde, 12-methyl-
2',3-Dimethyl[biphenyl]-4-amine
1-(2-Hydroxyethyl)-1-nitrosourea
Anti-4,5-dihydroxy-6,6a-epoxy-4,5,6,6a-tetrahydrobenzo[j]fluoranthene
(1aR,2R,3S,11dS)-1a,2,3,11d-Tetrahydroacenaphtho[1',2':7,8]naphtho[1,2-b]oxirene-2,3-diol
2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine
Nithiazide
Clonitralid
Dimethylaminoethylnitrosoethylurea, nitrite salt
Melphalan
Isonicotinic acid vanillylidenehydrazide
4-Hydroxy-2',4',6'-trichlorobiphenyl
2-Aminofluorene
Anti-dibenzo[a,l]pyrene-11,12-dihydrodiol-13,14-epoxide
Alachlor
Sodium beta-4-methoxybenzoyl-beta-bromoacrylate
Z-Ethyl-O,N,N-azoxyethane
Benzyl Violet 4B
Pyridalyl
N-Hexylnitrosourea
Dibenzo[a,i]pyrene
Dibenzo[a,h]pyrene
Oryzalin
Dibenzo[a,l]pyrene
Atrazine
C.I. Direct Black 38
C.I. Disperse Black 6 dihydrochloride
Daunorubicin
4-Biphenylamine hydrochloride
4-Methyl-1-[(5-nitrofurfurylidene)amino]-2-imidazolidinone
Cyanazine
Cytembena
(N-6)-(Methylnitroso)adenosine
Indium phosphide
Doxorubicin
17-Oxoestra-1(10),2,4-trien-3-yl benzoate
Captafol
11-Aminoundecanoic acid
N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide
Dinitrotoluene
Etridiazole
2-Hydrazino-4-(5-nitro-2-furyl)thiazole
2-(2,2-Dimethylhydrazino)-4-(5-nitro-2-furyl)thiazole
2-Hydrazino-4-(4-nitrophenyl)thiazole
2-Hydrazino-4-(4-aminophenyl) thiazole
Toluene diisocyanate
trans-5-Amino-3[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazole
Ethynodiol diacetate
Disulfoton
Hydrazine
Methylhydrazine sulfate
Chlormadinone acetate
Ochratoxin A
(S)-Furaltadone hydrochloride
Chlorambucil
N-(9-Oxo-2-fluorenyl)acetamide
5-Azacytidine
Formic acid 2-(4-methyl-2-thiazolyl)hydrazide
Pentaerythritol dibromide
Diuron
4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline
2,2-Bis(bromoethyl)-1,3-propanediol
Phenesterin
Formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide
alpha-Ecdysone
N-(2-Fluorenyl)-2,2,2-trifluoroacetamide
Procarbazine hydrochloride
AF-2
2-Amino-5-(5-nitro-2-furyl)-1,3,4-oxadiazole
Ifosfamide
Levofuraltadone
Ammonium perfluorooctanoate
C.I. Oxidation Base 12A
4-Acetylaminobiphenyl
2,2,2-Trifluoro-N-[4-(5-nitro-2-furyl)-2-thiazolyl]acetamide
1,8-Dinitropyrene
Dacarbazine
Metronidazole
Genistein
FD&C Green No. 1
Dibromomannitol
1,3-Diethyl-1-nitrosourea
Mitomycin C
Cyclophosphamide
Estriol
17beta-Estradiol
Benzo(a)pyrene
Reserpine
1-(2-Hydroxyethyl)-3-[(5-nitrofurfurylidene)amino]-2-imidazolidinone
Urethane
Norethindrone acetate
Amsacrine
N,N'-[6-(5-Nitro-2-furyl)-S-triazine-2,4-diyl]bisacetamide
Fenvalerate
Thiotepa
Lynestrenol
Estrone
Dibenz(a,h)anthracene
1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-Indole-3-acetic acid
N-Hydroxy-2-acetylaminofluorene
2-Acetylaminofluorene
Hexamethylolmelamine
Merphalan
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
Benzidine dihydrochloride
2-Chloroacetophenone
Dazomet
4-(5-Nitro-2-furyl)thiazole
Furosemide
Isoniazid
9H-Fluorene, 2,7-dinitro-
1,3-Dichloropropene
N-Nitrosodiethylamine
1,2-Dimethyl-5-nitroimidazole
N,N'-Dimethylnitrosourea
1-Nitropyrene
Ethalfluralin
Triclopyr
3-Iodo-2-propynyl-N-butylcarbamate
1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
Glycidol
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole
Bromochloroacetic acid
Carbon tetrachloride
Parathion
3-Methylcholanthrene
Diethylstilbestrol
1,3-Dibutyl-1-nitrosourea
C.I. Basic Red 9 monohydrochloride
Malachite green
N1-(Tris(hydroxymethyl))methyl-4-nitro-1,2-phenylenediamine
Glycidamide
Physostigmine
17alpha-Ethinylestradiol
Progesterone
7,12-Dimethylbenz(a)anthracene
2,3,4,7,8-Pentachlorodibenzofuran
4-Nitropyrene
Testosterone
2-Methoxy-3-aminodibenzofuran
Benzo(a)pyrene diolepoxide 1
4,6-Dimethyl-2-(5-nitro-2-furyl) pyrimidine
Nitrofurazone
Terbutylazine
Megestrol acetate
Dieldrin
5-Nitroacenaphthene
Carboxymethylnitrosourea
2-Nitrofluorene
Niridazole
3,3'-Dimethylbenzidine dihydrochloride
2-Aminoanthracene
N,N'-Diacetylbenzidine
Phenacetin
Ethyl methanesulfonate
Dichlorvos
Trp-P-2
1,1,1,2-Tetrachloroethane
17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione
N-1-Diacetamidofluorene
2-Methylaniline hydrochloride
N-(N-Methyl-N-nitrosocarbamoyl)-l-ornithine
Ethanol
C.I. Acid Red 114
Uracil mustard
Nitrofurantoin
2,3,4,5-Tetrachloro-4'-biphenylol
Norethindrone
Norethynodrel
Trans-7,12-Dimethylbenz(a)anthracene-3,4-dihydrodiol
Cyfluthrin
N-Nitroso-N-methylurea
Fluvalinate
Acronycine
Benzene
Medroxyprogesterone acetate
Bromodichloroacetic acid
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole
N-Hydroxy-N,N'-diacetylbenzidine
Mestranol
4,6-Diamino-2-(5-nitro-2-furyl)-s-triazine
Trp-P-2 acetate
1-Nitroso-1-ethyl-3-methylurea
Phosmet
4,4'-Diamino-2,2'-stilbenedisulfonic acid, disodium salt
6-Nitrochrysene
Vinyl chloride
Vinyl fluoride
Acetaldehyde
Dichloromethane
Ethylene oxide
1,1-Dichloroethane
1,1-Dichloroethylene
Nitromethane
Propyleneimine
1,2-Propylene oxide
3-(5-Nitro-2-furyl)-imidazo(1,2-alpha) pyridine
1,3-Dinitropyrene
Anti-3,4-Dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenzo(c)phenanthrene
1-Ethyl-1-nitrosourea
Trichloronitromethane
1-Allyl-1-nitrosourea
2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline
Sodium nitrite
4,4'-Sulfonylbisacetanilide
MeIQ
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
MeIQx
Isoprene
1,2-Dichloropropane
Hexythiazox
Trichloroethylene
Acrylamide
Norlestrin
Triasulfuron
Oxiran-2-yl hydrogen carbonimidate
Anti-1,2,3,10b-tetrahydrofluoranthene-2,3-diol 1,10b-oxide
Ametryn
4-aminostilbene
4,4'-Methylenebis(o-toluidine)
trans-N-Hydroxy-4-acetylaminostilbene
N-Butyl-N-nitrosourea
Ptaquiloside
2-Nitrotoluene
Bemitradine
3,3'-Dichlorobenzidine
4-Biphenylamine
C.I. Azoic Diazo Component 112
Methyleugenol
Prosulfuron
Sulfallate
2-Methylaniline
2,4-Diaminotoluene
Styrene oxide
1,2-Dibromo-3-chloropropane
2,3-Dibromopropanol
1,2,3-Trichloropropane
1-Ethylnitroso-3-(2-hydroxyethyl)urea
1-(2-Hydroxyethyl)-nitroso-3-ethylurea
Isoeugenol
o-Aminoazotoluene
Estradiol valerate
Nitrobenzene
5-Nitro-o-anisidine
2,4-/2,6-Dinitrotoluene mixture
Ionizing radiation
4-Nitrophenol
4-Vinylpyridine
Benzyl alcohol
Deisopropylatrazine
4-(2-Phenylpropan-2-yl)-N-[4-(2-phenylpropan-2-yl)phenyl]aniline
Triphenyl phosphite
Anilazine
Chlorpropham
2,4,6-Tris(allyloxy)-1,3,5-triazine
N-Phenyl-1,4-benzenediamine
4,4'-Methylenebis(N,N-dimethylaniline)
N-Isopropyl-N'-phenyl-p-phenylenediamine
4,4'-Diaminobiphenyl methane
Diphenylmethane
Dicyclohexylamine
17beta-Trenbolone
Triacetin
2,2-Dibromo-3-nitrilopropionamide
Fadrozole hydrochloride
Azobenzene
Benzyl cinnamate
Propylbenzene
N-Ethylaniline
Endosulfan sulfate
Flumioxazin
Octyl gallate
4-Nonylphenol
4-Dodecylphenol
3-Phenyl-2-propen-1-ol
1,2-Diphenoxyethane
5-Heptyldihydro-2(3H)-furanone
N,N'-Diethylthiourea
2,4-Dimethylphenol
Clodinafop-propargyl
2-(2,6-Diisopropylphenyl)-5-hydroxy-1H-isoindole-1,3-dione
Ethyl heptanoate
p-Cresol
4-Chloroaniline
4-Chlorophenol
4-Vinyl-1-cyclohexene dioxide
PharmaGSID_47337
SAR102608
Chloromethyl methyl ether
1-Methoxy-2-propanol
Sodium nonyl sulfate
Isopropyl acetate
m-Cresol
3-Methylaniline
1,3-Benzenediamine
Resorcinol
2,6-Dimethylpyridine
3,5-Dimethylphenol
Heptyl p-hydroxybenzoate
N,N'-Dibutylthiourea
2-Heptanone
Diisopropanolamine
Mepanipyrim
Dimethomorph
Butyl vinyl ether
Heptanal
Diethylene glycol monomethyl ether
Dodecyltrimethylammonium chloride
Nonanoic acid
10-Undecenoic acid
6-Methyl-3-hydroxypyridine
Zenarestat
Cycloate
Fenbuconazole
Endosulfan
Triphenyl phosphate
Novaluron
Quercetin
2-Aminoanthraquinone
Di(2-ethylhexyl) phthalate
2-Hydroxybenzophenone
Thiazopyr
Phenyl salicylate
3,3,5-Trimethylcyclohexyl salicylate
Benzyl salicylate
2,4,6-Tribromophenol
4,4'-Methylenebis(2,6-di-t-butylphenol)
Spiroxamine
Benzophenone
Sodium myristyl sulfate
Difenoconazole
Anthracene
Veratraldehyde
Naphthalene-2-sulfonic acid
4-(Diethylamino)benzaldehyde
Clorophene
1,3-Diphenyl-1,3-propanedione
Ethylparaben
Benzyl benzoate
Ethylenebis(oxyethylene) dibenzoate
2-Methoxy-5-methylaniline
1,2-Benzenediol
2,4-Dichlorophenol
Anastrozole
4,6-Dimethyldibenzothiophene
2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)-2-propanol
2-tert-Butyl-4-methoxyphenol
4-Hydroxy-3-methoxybenzaldehyde
N,N,3-Trimethylaniline
Propyl gallate
N-Benzyladenine
Cyprodinil
Octylparaben
Fenitrothion
Diphenylamine
Propham
Chlorfenapyr
Sulfentrazone
Rimsulfuron
4-Ethylphenol
Hydroquinone
Isopentyl alcohol
1-Dodecanamine
Triamcinolone
2-Ethylhexyl diphenyl phosphate
Maneb
Aminoglutethimide
Metconazole
4,4-Bis(4-hydroxyphenyl)valeric acid
Carminic acid
Fenhexamid
Retinol acetate
alpha-Isomethylionone
Zamifenacin
Sodium dimethyldithiocarbamate
1,4-Diaminoanthraquinone
Carfentrazone-ethyl
Pyrene
Pyraflufen-ethyl
1,6-Hexanediol diacrylate
Terbufos
Dimethyl phthalate
Diallyl phthalate
Dipentyl phthalate
2,2',4,4'-Tetrahydroxybenzophenone
2,4-Dihydroxybenzophenone
2-Hydroxy-4-methoxybenzophenone
Fludioxonil
Cresol
Ethoprop
Triticonazole
Rifampicin
Tris(methylphenyl) phosphate
Methylionone
Sorbitan, mono-(9Z)-9-octadecenoate
Epoxiconazole
4-Chlorobenzophenone
2-Naphthalenol
Cupferron
2,2'-Dibenzoylaminodiphenyl disulfide
N-Phenyl-2-naphthylamine
Acibenzolar-S-methyl
Mefenpyr-diethyl
4-Hexylresorcinol
5-Methyl-1H-benzotriazole
FR130739
3-Phenoxybenzenemethanol
FR 409
Sodium phenolate
Nitrilotriacetic acid
Darbufelone mesylate
E-Cinnamic acid
Fenaminosulf
4-(1,1,3,3-Tetramethylbutyl)phenol
4-Methylpent-3-en-2-one
1-Monolaurin
1-Nonanol
Kepone
Phenol red
Kresoxim-methyl
(2E)-3-Phenylprop-2-enal
CP-122721
Dimethyl isophthalate
Diphenhydramine hydrochloride
Indan-5-ol
Bisphenol AF
Phoxim
Spirodiclofen
1,3-Dichloro-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline hydrochloride (1:1)
4-Pentylphenol
Tepraloxydim
3-Methoxyphenol
Difpas-pyrazole
Napropamide
Diclofenac sodium
Benodanil
SR271425
4-Nitrosodiphenylamine
1-Benzylquinolinium chloride
2,3-Dihydro-2,2-dimethyl-7-benzofuranol
Carbofuran
4-Chloro-2-methylphenol
Trifluralin
Cariporide mesylate
Daminozide
Prometon
(S)-1-Anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one
UK-156819
4-Butylphenol
4-(tert-Pentyl)-cyclohexanone
3-Hydroxy-2-pyridone
Chloridazon
CP-283097
Cyclododecanol
1,4-Bis(butylamino)anthracene-9,10-dione
1,1-Bis(3,4-dimethylphenyl)ethane
6-Methoxy-2-benzothiazolamine
Neopentyl glycol diglycidyl ether
Phenylparaben
Prothioconazole
Zearalenone
CJ-013790
4-Octylphenol
SR144190
Nitrofen
Octabenzone
Chlorthal-dimethyl
Benfluralin
Phenyl carbonochloridate
Trelanserin
4-(Hexyloxy)phenol
4-Heptylphenol
CP-401387
p-Anisidinium chloride
Methiocarb
Benzo(b)fluoranthene
Fluoranthene
Acenaphthylene
EPN
CP-456773
2-(3-Phenylpropyl)pyridine
Tonalide
Vatalanib dihydrochloride
Ethyl 1-naphthaleneacetate
2-Ethylhexyl 4-(dimethylamino)benzoate
3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctyl methacrylate
CP-457677
UK-343664
(4Z)-4-Decenal
CP-457920
Molinate
1,5-Naphthalenediamine
Bendiocarb
Prallethrin
Phosalone
Antioxidant 1098
Formetanate hydrochloride
Damascenone
(E)-beta-Damascone
Mirex
Basic Blue 7
Dexamethasone sodium phosphate
Propyzamide
4-tert-Butylbenzenethiol
2,3,6-Trimethylphenol
4-Cyclohexylcyclohexanol
2-(2H-Benzotriazol-2-yl)-4-methylphenol
Barium bis(2-ethylhexanoate)
Tridemorph
1,3-Phenylenedi(4-aminophenyl ether)
C.I. Solvent Yellow 56
Methyl dihydrojasmonate
2-Bromo-4-hydroxyacetophenone
Sodium 2-mercaptobenzothiolate
Disulfoton sulfone
Isofenphos
Besonprodil
1,3,5,7-Tetramethyl-1,3,5,7-tetravinylcyclotetrasiloxane
Phenothrin
Glycols, polyethylene, mono(p-nonylphenyl) ether
5-Chloro-2-methyl-3(2H)-isothiazolone
HMR1426
Azinphos-ethyl
N,N-Dimethylacrylamide
2,3-Diaminotoluene
Dodecylphenol
Silwet L 77
Norflurazon
Disodium 4,4'-bis(2-sulfostyryl)biphenyl
2,4-Bis(1-methyl-1-phenylethyl)phenol
FD&C Yellow 6
4,4',4''-Ethane-1,1,1-triyltriphenol
Cybutryne
C.I. Disperse Yellow 3
5-Amino-2-methylphenol
Dimethylnaphthalene
Surinabant
CP-634384
Melengestrol acetate
Chlorpyrifos
Pirimiphos-methyl
2,4-Diisopropylphenol
Tolyltriazole
Triethoxyoctylsilane
2,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethane
Methyl parathion
Phorate
SSR180711
all-trans-Retinoic acid
Stavudine
C.I. Solvent Orange 7
3-Methyl-4-(methylthio)phenol
Propetamphos
MK-578
Bromacil
1,4-Dihydroxy-2-naphthoic acid
beta-Hexachlorocyclohexane
Acetylcedrene
Procymidone
Tris(2-ethylhexyl) trimellitate
4-Pentylaniline
Diazinon
Butralin
Terbumeton
Isopropalin
PharmaGSID_47263
Butam
CP-612372
Sulprofos
Imazalil
4-Fluoro-3-nitroaniline
3-(3,5-Dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide
CP-728663
Fenpropathrin
Pendimethalin
Sulisobenzone
Profenofos
4,4'-Sulfonylbis[2-(prop-2-en-1-yl)phenol]
Isazofos
Cyproterone acetate
Oxyfluorfen
Cladribine
Tripropylene glycol diacrylate
MEHP
Nelivaptan
Cyclopamine
CP-671305
N-Methyldioctylamine
Azathioprine
3-Phenylhexane
1,2-Diphenylethanone
2,3-Diaminopyridine
PharmaGSID_48510
Farnesol
Ethylene dimethanesulfonate
Methyl 3-methylorsellinate
Diphenyl phosphite
Equilin
SSR161421
Chrysin
7,4'-Dihydroxyisoflavone
5,7-Dimethoxy-2H-chromen-2-one
1,5,9-Cyclododecatriene
Biochanin A
2-Ethyl-3-hydroxy-4-pyrone
Glycoluril
3,4-Diaminotoluene
3-Methyl-4,6-di-tert-butylphenol
Isopropyl-o-cresol
DDT
4-Butyl-1,2-diphenyl-3,5-Pyrazolidinedione
Aspirin
Nordihydroguaiaretic acid
PD-0333941
1,3-Propanediol
Acifluorfen
Piperonyl butoxide
Tiratricol
6-Propyl-2-thiouracil
(+-)-Diclofop-methyl
2-Ethylhexyl p-hydroxybenzoate
1-(Bromomethyl)-3-phenoxybenzene
Spironolactone
Trichlorfon
Kaempferol
Apigenin
5alpha-Dihydrotestosterone
Cypermethrin
Carboxin
Kinetin
Flavone
Permethrin
Prednisone
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane
Dehydroepiandrosterone
1-Hydroxypyrene
Sodium 2-naphthalenesulfonate
4-(2-Methylbutan-2-yl)cyclohexanol
Triisononyl trimellitate
(Z)-11-Hexadecenal
Nicotine
4-Iodophenol
Chlorethoxyfos
Gentian Violet
Fenthion
Triadimenol
Carbosulfan
Dimethipin
4,4'-Bipyridine
Pyridate
Chlorpyrifos-methyl
Benz(a)anthracene
Coumaphos
Tri-m-tolyl phosphate
Ethion
Octadecanoic acid
Chlordane
Testosterone propionate
17alpha-Estradiol
Metalaxyl
17-Methyltestosterone
Theophylline
Triphenylethylene
Hydrochlorothiazide
3-Phenylphenol
2,5-Dichlorophenol
3-tert-Butylphenol
Diphenylmercury(II)
Isobornyl acrylate
Folic acid
4-Chloro-3-methylphenol
1-Methyl-3-phenyl-5-(3-(trifluoromethyl)phenyl)-4-pyridone
4-Cumylphenol
C.I. Solvent Yellow 1
Fenarimol
2,3-Dinitrotoluene
Triphenylphosphine
Triphenylstibine
Diisopropyl phthalate
Cyclophosphamide monohydrate
2,6-Dinitrotoluene
1,2,3,4,5,6-Hexachlorocyclohexane
6-Hydroxy-2-naphthyl disulfide
Methylene blue
3,4-Dinitrotoluene
2-Hydroxybenzonitrile
3,3'-Dichlorobenzidine dihydrochloride
1,3-Dihydro-2H-inden-2-one
Sodium 2-phenylphenate tetrahydrate
Oxytetracycline dihydrate
3-Isopropylphenol
Deethylatrazine
(+/-)-cis-Permethrin
Phenylmercuric acetate
3-Ethylphenol
Bis(4-hydroxyphenyl)methane
1,4-Benzenediamine dihydrochloride
Hexyl salicylate
2-Chloro-5-nitroaniline
1-Pentadecanol
Flumetralin
4-Androstene-3,17-dione
Carbaryl
C.I. Acid Orange 7
3-Hydroxyfluorene
Benzyl-C8-18-alkyldimethylammonium chlorides
2-Amino-6-chloro-4-nitrophenol
C.I. Solvent Red 80
Ethyl 4-chloro-3-oxobutanoate
4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
4-Propylphenol
2-Ethyl-2-hexenal
Ketoconazole
Morin hydrate
Esfenvalerate
Flutolanil
Fenoxaprop-ethyl
Colforsin
Irganox 1010
CP-863187
Hydramethylnon
PD 0343701
Prochloraz
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluoro-1-decanol
Retinol
17alpha-Hydroxyprogesterone
Dibutyltin dichloride
2,2,4-Trimethyl-1,3-pentanediol diisobutyrate
DINP branched
C.I. Acid Orange 156
PharmaGSID_48519
Triflumizole
3,5,3'-Triiodothyronine
Didecylmethyl(3-(trimethoxysilyl)propyl)ammonium chloride
Cytarabine hydrochloride
Dihydrojasmone lactone
N-(3,4-Dichlorophenyl)propanamide
Cyclohexylphenylketone
Fenoxaprop-P-ethyl
Abamectin
Methoxychlor
p,p'-DDD
p,p'-DDE
Prometryn
Melatonin
N,N-Dimethyloctylamine
Sethoxydim
Bensulide
Diphenyl isophthalate
Perfluorooctanesulfonamide
Trichloroacetic acid
Quizalofop-ethyl
4-Hydroxybenzonitrile
Paclobutrazol
Phenolphthalein
Bisphenol B
Lactofen
Sodium chlorite
Tri-o-cresyl phosphate
2,5-Dimethyl-2,5-di-(tert-butylperoxy)hexane
Enterolactone
o,p'-DDT
Methacrylamide
3,3',5,5'-Tetrabromobisphenol A
2,2',6,6'-Tetrachlorobisphenol A
3,3'-Dimethylbisphenol A
Fluazifop-P-butyl
Tefluthrin
Levonorgestrel
Simvastatin
Bisphenol A
Dapsone
4,4'-Sulfonyldiphenol
Dicumyl peroxide
4-(2-Methylbutan-2-yl)phenol
Clove leaf oil
Anise oil
Mancozeb
Phenolphthalin
Tributyltetradecylphosphonium chloride
Clomazone
2-Hydroxyethyl acrylate
1-Chloroanthraquinone
Sodium saccharin hydrate
Isoxaben
Bifenthrin
Sodium m-xylene-4-sulfonate
1-Methyl phenanthrene
Diniconazole
meso-Hexestrol
Dicyclohexyl phthalate
Diethyl phthalate
Diisobutyl phthalate
1,2-Benzenedicarboxylic acid, dibutyl ester
C.I. Solvent Yellow 14
Mifepristone
4-Nonylphenol, branched
Benzyl butyl phthalate
1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
9-Ethylcarbazole
N-Nitrosodiphenylamine
Azinphos-methyl
4,7-Dichloroquinoline
Dimethyl phosphonate
7-(Dimethylamino)-4-methylcoumarin
4-tert-Butylphenyl salicylate
2,6-Dimethylaniline
Hexachloro-1,3-butadiene
Pentachlorophenol
Flumiclorac-pentyl
Cinmethylin
4-Chloro-3,5-dimethylphenol
2,4,6-Trichlorophenol
2-Tert-Butyl-5-methylphenol
2-Isopropylphenol
2-Nitroaniline
2-(Butan-2-yl)phenol
Thymol
1,3-Dimethyl-4-nitrobenzene
Salicylaldehyde
1-Naphthol
N-Phenyl-1-naphthylamine
2-Phenylphenol
Polymethylene polyphenyl polyisocyanate
2,6-Dimethoxyphenol
Ethoxyquin
2-Naphthylamine
3-Aminopropyltriethoxysilane
2-Chloro-4-phenylphenol
2,3-Dihydroxynaphthalene
4-Cyclohexylcyclohexanone
4-Phenylphenol
Phenothiazine
4'-Acetylbiphenyl
4-Prop-1-enylveratrole
Propylparaben
Benzyl 4-hydroxybenzoate
4-Hydroxybenzoic acid butyl ester
2-Phenylethyl benzoate
Dimethyl cyclohexane-1,4-dicarboxylate
MCPA
2,4-D Butyl ester
2-Ethoxy-5-(1-propenyl)phenol
1-Phenyl-1H-pyrrole-2,5-dione
Cyproconazole
1H-Indene
2-(8-Heptadecenyl)-2-imidazoline-1-ethanol
1,2-Dichlorobenzene
1,2-Phenylenediamine
2-Chlorophenol
3,4-Dimethylphenol
4-Chloro-2-methylaniline
3,4-Dichloroaniline
4-Chloro-1,2-diaminobenzene
2,4,5-Trichlorophenol
Methidathion
Pyriproxyfen
Endosulfan I
2-tert-Butyl-4-ethylphenol
Iopanoic acid
Triphenylborane
Pyridaben
Dichlorophen
2-Methoxy-4-nitroaniline
Eugenol
Dithiopyr
4-tert-Butylcatechol
4-(1,1-Dimethylethyl)phenol
3-Dimethylaminophenol
C.I. Azoic Diazo Component 12
4-(Butan-2-yl)phenol
Methylparaben
alpha-Terpinene
4-Isopropylphenol
N,N,4-Trimethylaniline
Cloquintocet-mexyl
CI-1018
CP-642931
CI-1044
CP-422935
GSK163929B
PharmaGSID_47330
MK-968
AVE8488
SAR115740
AVE6324
PharmaGSID_48514
PharmaGSID_48516
 

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