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BREAKING NEWS
Source: University of Luxembourg  Mar 04, 2019  5 years, 1 month, 2 weeks, 1 day, 15 hours, 38 minutes ago

Regenerative Medicine On The Horizon With Latest Success Of Rejuvenating Stems Cells From An Aging Brain

Regenerative Medicine On The Horizon With Latest Success Of Rejuvenating Stems Cells From An Aging Brain
Source: University of Luxembourg  Mar 04, 2019  5 years, 1 month, 2 weeks, 1 day, 15 hours, 38 minutes ago
Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg and from the German Cancer Research Center (DKFZ) have been able to rejuvenate stem cells in the brain of aging mice. The revitalised stem cells improve the regeneration of injured or diseased areas in the brain of old mice. The researchers expect that their approach will provide fresh impetus in regenerative medicine and facilitate the development of stem cell therapies.
regenerative medicine
Brain Stem Cells

Their results were published today in the journal Cell. All cells making up our organs originate from stem cells. They divide and the resulting cells develop into specific tissue cells, forming the brain, lungs or bone marrow. With age, however, the stem cells of living organisms lose their ability to proliferate. Many of them lapse into a permanent state of quiescence.

In order to create as accurate as possible computational models of stem cell behaviour, the LCSB's Computational Biology Group led by Prof. Antonio del Sol applied a novel approach. "Stem cells live in a niche where they constantly interact with other cells and extra-cellular components. It is extremely difficult to model such a plethora of complex molecular interactions on the computer. So we shifted perspective. We stopped thinki