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Angiogenesis literally means creation of new blood vessels. The word “angio” means blood vessels while “genesis” means creation.
Angiogenesis is an important process that occurs both during health and disease. Blood is important in the body as it carries oxygen and nutrients to all the parts of the body via blood vessels like arteries and brings back the toxins and wastes from these peripheral organs for purification via veins.
When a new tissue is formed, it is vital that it has blood supply for its growth and sustenance. For this formation of blood vessels or angiogenesis is important.
Formation of new tissues involves formation of new blood vessels. Some of the normal situations where angiogenesis is important and necessary include those for repair of wounds and the formation of the placenta during pregnancy.
The normal body has controls over the process of angiogenesis. These are complex and intricate pathways. There are several “on” and “off” switches that regulate the process. The “on” switches are some chemicals that stimulate blood vessel formation while “off” switches are chemicals that inhibit blood vessel-formation.