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Source: Thailand Medical News  Jan 08, 2020  4 years, 9 months, 5 days, 30 minutes ago

New Ketone Monoester Drinks To Control Blood Sugar

New Ketone Monoester Drinks To Control Blood Sugar
Source: Thailand Medical News  Jan 08, 2020  4 years, 9 months, 5 days, 30 minutes ago
As more people with diabetes and pre-diabetes are looking for strategies to help control blood sugar, new research from University of British Columbia's Okanagan campus suggests that ketone monoester drinks, a popular new food supplement may help do exactly that.

Dr Jonathan Little, Associate Professor at UBC Okanagan's School of Health and Exercise Sciences and study lead author told Thailand Medical News, "There has been a lot of excitement and interest in ketone drinks and supplements, which have really only been on the market and available to consumers for the last couple of years. Because they're so new, there's very little research on how they can influence metabolism and we're among the first to look at their use in non-athletes."


UBC researcher Dr Jonathan Little suggests ketone supplement drink may
help control blood sugar.
Credit: UBC Okanagan


Dr Little says that type 2 diabetes is a disease whereby the body is unable to control the level of sugar in the blood because defects in the functioning of a hormone called insulin.

He added,  "It's a disease that's becoming alarmingly common in Canada and approaching what many would consider epidemic levels. While type 2 diabetes can be controlled with medications or injectable insulin, many people are looking to options that don't require taking pills every day or that are less invasive."

Currently, ketone supplements are proving fertile ground for research into type 2 diabetes because, according to Dr Little, ketones are the natural fuel source of the body when it's in ketosis, the metabolic byproduct of consuming a low carbohydrate, ketogenic diet.

Dr Little further added, "There is mounting evidence that a low carbohydrate ketogenic diet is very effective in controlling blood sugar and even reversing type 2 diabetes. We wanted to know what would happen if artificial ketones were given to those with obesity and at risk for type 2 diabetes but who haven't been dieting."

To assess the idea, Dr Little and his team asked 15 people to consume a ketone drink after fasting overnight. After 30 minutes, they were then asked to drink a fluid containing 75 grams of sugar while blood samples were taken.

Dr Little explained, "It turns out that the ketone drink seemed to launch participants into a sort of pseudo-ketogenic state where they were better able to control their blood sugar levels with no changes to their insulin. It demonstrates that these supplements may have real potential as a valuable tool for those with type 2 diabetes."

Dr Little is quick to point out that ketone supplements are not a magic bullet in managing the disease.

He cautioned, "There are a number of problems that we still have to work out, including the fact that we still don't know what the long-term effects of consuming ketones are. And not to mention that the drink itself tastes absolutely terrible. But for those that aren't able to follow a strict and challenging ketogenic diet or for those that are looking for a new way to control blood sugars, this may be another strategy in helping to manage type 2 diabetes."

Thailand Medical News also warns that there has been past studies showing that individuals on ketogenic diets have been prone to kidney diseases and kidney failure. Before attempting any diets or supplements, all individuals are advised to consult their doctors first.
 
Reference : Étienne Myette-Côté et al, A ketone monoester drink reduces the glycemic response to an oral glucose challenge in individuals with obesity: a randomized trial, The American Journal of Clinical Nutrition (2019). DOI: 10.1093/ajcn/nqz232
 

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