Acute Kidney Injury: Study Shows That Acute Kidney Injury (AKI) Predominant Among COVID-19 Patients
Acute Kidney Injury
: According to a study published in The British Medical J
ournal or BMJ, most hospitalized COVID-19 patients faced major morbidity and mortality, with 78.0 percent of those admitted to the intensive care unit (ICU) developing acute kidney injury or AKI. https://www.bmj.com/content/369/bmj.m1996
Dr Michael G. Argenziano, from Columbia University in New York City, and colleagues characterized patients hospitalized with COVID-19 in New York City and described their clinical course.
The initial 1,000 consecutive COVID-19 patients who presented to the emergency department or were admitted to the hospital at the New York-Presbyterian/Columbia University Irving Medical Center between March 1 and April 5, 2020, were included.
The medical researchers found that 614 patients were admitted to the hospital and 236 were admitted or transferred to ICUs. The most common presenting symptoms were cough, fever, and dyspnea (732, 728, and 631 patients, respectively).
Typical baseline comorbidities, including hypertension, diabetes, and obesity, were often seen in patients in the hospital, especially those treated in ICUs.
Interestingly most patients admitted to the ICU were older and mainly male (66.9 percent) and had long lengths of stay (median, 23 days).
Significantly 78.0 percent developed acute kidney injury and 35.2 percent required dialysis.
Six of 136 patients who required mechanical ventilation (4.4 percent) were first intubated more than 14 days after symptom onset.
The researchers commented, "The research study found that patients in hospital with COVID-19 in New York City had high rates of baseline comorbidities and a substantial proportion developed complications compared with previously studied U.S. and international cohorts. Our characterization of patients could provide anticipatory guidance as the pandemic continues around the world."
It was noted that several of the researchers on the team disclosed financial ties to the pharmaceutical industry.
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