American Researchers Warn That New COVID-19 Strains May Trigger Dangerous Bleeding Disorder!
Nikhil Prasad Fact checked by:Thailand Medical News Team Oct 22, 2025 4 months, 2 weeks, 6 days, 18 hours, 46 minutes ago
Medical News: Mysterious Link Between COVID-19 and Acquired Haemophilia A
A new study by researchers from SUNY Downstate College of Medicine in Brooklyn, Mount Sinai West Hospital in New York, NYU Grossman Long Island School of Medicine in Mineola, and the National Institutes of Health in Bethesda has revealed that both SARS-CoV-2 infection and vaccination can trigger a rare but potentially fatal bleeding disorder called Acquired Haemophilia A (AHA). The researchers found that the immune system of some individuals, especially older adults, may mistakenly attack the body’s own blood-clotting proteins after exposure to the virus or vaccine. This
Medical News report highlights how these findings raise serious concerns about new and emerging COVID-19 strains like Omicron, which may further increase risks.
American Researchers Warn That New COVID-19 Strains May Trigger Dangerous Bleeding Disorder
How the Virus and Vaccine Trigger the Disorder
AHA occurs when the immune system produces antibodies that destroy Factor VIII, a protein vital for blood clotting. Without it, even small injuries can lead to uncontrollable bleeding. The study analyzed 42 cases of AHA—14 following COVID-19 infection and 28 after vaccination. Infected individuals tended to develop the disorder faster and more severely than vaccinated ones, sometimes resulting in haemorrhagic shock. Interestingly, the researchers discovered that the spike protein of the SARS-CoV-2 virus shares two surface regions, known as epitopes, with the human Factor VIII protein. One of these overlaps was found only in the Omicron variant, suggesting that newer strains might trigger stronger immune cross-reactions.
Implications for Future COVID Variants and Treatment
The scientists warn that as the virus continues to mutate, more cases of AHA might appear, particularly among older or genetically vulnerable individuals. Doctors are urged to monitor unexplained bleeding in COVID-19 or recently vaccinated patients and to test for anti-Factor VIII antibodies early. Understanding this immune cross-talk could help prevent severe complications and guide safer vaccine or antiviral designs. The researchers conclude that early diagnosis and treatment are critical, as rapid medical intervention can save lives and prevent long-term damage caused by this rare autoimmune reaction.
The study findings were published in the peer-reviewed Journal of Thrombosis and Haemostasis.
https://www.jthjournal.org/article/S1538-7836(25)00649-X/abstract
For the latest COVID-19 news, keep on logging to Thailand
Medical News.
Read Also:
https://www.thailandmedical.news/articles/coronavirus
Share
Tweet
Share
