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Calcium is the most abundant mineral in the human body, making up about 2% of the total body weight. Some of the roles calcium plays in the body are described below.
The main role of calcium in the body is to provide structure and strength to the skeleton. In the earliest forms of exoskeleton and in shells, the structural rigidity is generally provided by calcium carbonate. In vertebrates such as reptiles, fish, mammals and humans, the structure of the skeleton is mainly provided by a form of calcium phosphate called hydroxyapatite crystals, which are found in collagen. Calcium ions on bone surfaces interact with those present in the bodily fluids, therefore enabling ion exchange, which is essential in maintaining the balance of calcium in the blood and bone.
In the extracellular fluid, calcium serves as a reservoir for circulating calcium. This calcium enters the extracellular fluid via the gastrointestinal tract where it is absorbed from the food a person has eaten. Calcium also becomes available through a process called bone resorption, which is the breakdown of bone tissue by cells called osteoclasts.
Calcium circulating in the blood is involved in several vital processes including coagulation, nerve signal transmission, hormone signalling and muscle contraction.