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Cancer
Keeping you updated with all the latest developments, researches, drug trials and treatment protocols for cancer. For detailed information about cancer including cancer types, cancer treatments, cancer drugs, cancer care and also the best cancer hospitals and cancer doctors in Thailand, please visit our other website: www.thailandcancerhelp.com
Source: Thailand Medical News  Jun 01, 2019  3 years ago
Scientists at Wake Forests School Of Medicine,North Carolina, conducted a therapeutic study of the effects of using non-thermal radio waves on liver cancer cells. The study concluded that the new targeted therapy has proven to be successful in blocking the growth of liver cancer cells anywhere in the body without damaging healthy cells   The research team headed by Boris Pasche, M.D., Ph.D....
Source: Thailand Medical News  May 25, 2019  3 years ago
There are more than 1.1 million new cases of men diagnosed with Prostate Cancer each year while about 310,000 of them die annually due to the disease. (Figures from Globoscan). Here Thailand Medical News brings you in summarized form, developments this week from across the globe with regards to prostate cancer research and developments for easy reading.     Biomaker, PSA contributes to...
Source: Thailand Medical News  May 23, 2019  3 years ago
Despite the advances in both Immunotherapy and  Targeted Medicine protocols for the treatment of cancer, Chemotherapy is still going to be the mainstay for the next decade or so for  most of Asia due to cost factors and also availability. In fact, statistical data shows the figure of chemotherapies would most likely double by 2025 in Asia from current  2019 levels. But what is tr...
Source: Institute of Cancer Research, UK  May 07, 2019  3 years ago
Scientists have identified a gene mutation in the tumours of men with prostate cancer that is linked to very poor survival—and which could be used to pick out patients for more intensive treatment. Men with mutations in the retinoblastoma gene in their tumours were more than three times as likely to die and nearly seven times as likely to relapse on standard treatments as those without th...
Source: Karolinska Institutet  May 05, 2019  3 years ago
Researchers at Karolinska Institutet in Sweden have identified blood-based biomarkers that may determine which patients will benefit from continued hormonal therapy for advanced prostate cancer. The researchers envision that this discovery may eventually result in a test that contributes to a more personalised treatment of the disease. Prostate cancer is the most common male cancer in Sweden. App...
Source: Proceedings froms ESTRO 2019, Milan  Apr 29, 2019  3 years ago
A single high dose of radiation that can be delivered directly to the tumour within a few minutes is a safe and effective technique for treating men with low risk prostate cancer, according to a study presented at the ESTRO 38 conference. Radiotherapy traditionally involves a series of lower dose treatments that take place over several days or week. The new treatment is called high dose-rate br...
Source: Proceedings froms ESTRO 2019, Milan  Apr 28, 2019  3 years ago
For females with hormone-driven breast cancer, adding radiation to hormone therapy might keep their cancer from coming back for up to a decade, a new study finds. Breast cancer didn't come back in the same breast for 97.5% of women who had radiation therapy plus hormone therapy compared to just over 92% of women who had hormone therapy alone, the researchers said. In addition, over the stu...
Source: Thomas Jefferson University  Apr 26, 2019  3 years ago
A new colorectal cancer vaccine showed positive results in the phase 1 clinical trial to demonstrate that the approach is safe. The patients treated had no signs of serious adverse events and samples of their blood contained markers of immune activation—an early indication that the vaccine could activate immune cells to fight colorectal tumors and metastases. Further tests to determine if th...
Source: Beth Israel Deaconess Medical Center  Apr 21, 2019  3 years ago
About one in seven women in the world will develop breast cancer in her lifetime. The vast majority of these cancers depend on the hormone estrogen to grow. Estrogen-receptor positive (ER+) breast cancer tumors are frequently treated with the drug tamoxifen, which blocks the hormone's effect on the tumor. However, many tumors eventually become resistant to tamoxifen, allowing cancer to recur o...
Source: University Of Otago  Apr 17, 2019  3 years ago
Oral cancer is known for its high mortality rate in developing countries, but an international team of scientists hope its latest discovery will change that. Researchers from the University of Otago, New Zealand, and the Indian Statistical Institute (ISI), Kolkata, have discovered epigenetic markers that are distinctly different in oral cancer tissues compared to the adjacent healthy tissues in...
Source: University of Michigan  Apr 07, 2019  3 years ago
A potential new immune-based therapy to treat precancers in the cervix completely eliminated both the lesion and the underlying HPV infection in a third of women enrolled in a clinical trial. The shot, a therapeutic vaccine, injects a specific protein that triggers an immune system response to attack high-risk HPV types that cause nearly all cervical cancer precursors, known as cervical intraep...
Source: Boston University School of Medicine  Mar 26, 2019  3 years ago
Researchers have identified a biomarker and a possible new therapy for melanoma.   Microphthalmia-associated transcription factor (MITF) is a protein that plays a pivotal role in the maintenance of the melanocyte ( cells that make melanin) lineage, differentiation of normal and malignant melanocytes and the survival of melanoma cells.   "We have now detected the first useful chemi...
Source: Baylor College of Medicine  Mar 22, 2019  3 years ago
Does sugar directly feed cancers, boosting their growth? The answer seems to be 'Yes' at least in mice according to a study led by researchers at Baylor College of Medicine and Weill Cornell Medicine. Their study showed that consuming a daily modest amount of high-fructose corn syrup -- the equivalent of people drinking about 12 ounces of a sugar-sweetened beverage daily -- accelerates the...
Source: George Washington University  Mar 17, 2019  3 years ago
Researchers at the George Washington University (GW) Cancer Center found that the enzyme USP15 could potentially lead to new treatments for breast and pancreatic cancer. Their findings were published in Nature Communications. "With this study, we validate the role of USP15 in maintaining genome stability and tumor suppression and inform novel treatments for breast cancer," said H...
Source: American Society for Biochemistry and Molecular Biology  Mar 16, 2019  3 years ago
Fewer than half of ovarian cancer patients survive until five years after diagnosis. According to the American Cancer Society, this is because only about one-fifth of ovarian cancer cases are detected early, when the chances of successful treatment and recovery are highest.   "If we could change this reality by detecting ovarian cancer at a curable stage, we could save many lives,"...
Source: Institute of Cancer Research, London  Mar 10, 2019  3 years ago
Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals. Scientists found that PARP inhibitors sparked a powerful immune response when used against cancer cells with weaknesses in repairing their DNA.   The study changes our understanding of how PARP inhibito...
Source: Columbia University, Irving Medical Center   Mar 10, 2019  3 years ago
Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum-- a common oral bacteria often implicated in tooth decay -- accelerates the growth of colon cancer.  The findings could make it easier to identify and treat more aggressive colon cancers. It also helps explain why some cases advance far more quickly than others, thanks to the same bacter...
Source: NRG Oncology, Pennsylvania  Feb 17, 2019  3 years ago
The NRG Oncology clinical study NRG-RTOG 0415 determined that a hypofractionated radiotherapy schedule (H-RT), a treatment schedule that delivers a total dose of radiotherapy over a shorter period of time, is not worse than the conventional radiotherapy schedule (C-RT) in terms of bowel, bladder, sexual, and general quality of life (QOL) as well as anxiety and depression for men with low risk pros...
Source: ETH Zurich University  Feb 15, 2019  3 years ago
In recent years, the number of targeted cancer drugs has continued to rise. However, conventional chemotherapeutic agents still play an important role in cancer treatment. These include platinum-based cytotoxic agents that attack and kill cancer cells. But these agents also damage healthy tissue and cause severe side effects. Researchers at ETH Zurich have now identified an approach that allows fo...
Source: University of Cambridge/ University of Leicester  Feb 13, 2019  3 years ago
A blood test has been developed that could save countless lives by improving early detection of lung cancer. The test measures circulating DNA that is shed by cancer cells as they grow and multiply. Scientists believe it could predict the presence of low-grade tumours in the lungs long before they become a threat.   New research led by scientists at the Medical Research Council (MRC) Toxico...
Source: The Institute of Cancer Research, London  Feb 10, 2019  3 years ago
A brand new type of cancer drug that acts as a ‘Trojan horse’ to get inside tumour cells has shown promise in patients with six different cancer types. In patients with advanced, drug-resistant cancers, over a quarter with cervical and bladder tumours, and nearly 15 per cent with ovarian and lung tumours, responded to the new treatment. The innovative new drug, called tisotumab ved...
Source: Charité - Universitätsmedizin Berlin  Feb 03, 2019  3 years ago
Researchers at Universitätsmedizin Berlin have discovered a protective mechanism which is used by the body to protect intestinal stem cells from turning cancerous. The body's innate immune system was found to play a pivotal role in this regard. The researchers were able to demonstrate that, rather than having a purely defensive role, the immune system is crucial in maintaining a healthy b...
Source: Memorial Sloan Kettering Cancer Center  Jan 25, 2019  3 years ago
A team of researchers from Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College used genetic testing of cells found in cerebrospinal fluid to track certain brain tumors. In their paper published in the journal Nature, the group describes tests they conducted with cancer patients and analysis of their cerebrospinal fluid, and what they found. Doctors who treat patients w...
University of California - Los Angeles Health Sciences  Jan 18, 2019  3 years ago
UCLA researchers have developed the first technique for turning certain stem cells into mature T cells capable of fighting cancer. The university announced on  January  17th  2019,  that its scientists had developed a technique for coaxing pluripotent stem cells – which can create cell in the body and be grown in a lab – into T cells that can attack tumors. Immun...
Source: University of Texas MD Anderson Cancer Center  Jan 12, 2019  4 years ago
Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers. The University of Texas MD Anderson Cancer Center research team found overexpression of the immune checkpoint VISTA on immune cells, especially macrophages, that infiltr...
Source: University Health Network  Jan 08, 2019  4 years ago
A clinical-scientific team specializing in head-and-neck cancer has identified a way to manipulate metabolism to potentially curb skin fibrosis -- a common side effect of radiotherapy affecting quality of life of cancer survivors. The study findings from the laboratory of principal investigator Dr. Fei-Fei Liu, Chief, Radiation Oncology, Princess Margaret Cancer Centre, University Health Networ...
Source: Princeton University  Jan 04, 2019  4 years ago
By simultaneously tackling two mechanisms for cancer's growth, an experimental therapy reduced the spread of triple-negative breast cancer in a study conducted in mice. The therapeutic agent, called Tinagl1, is based on a naturally occurring protein and blocks two of the main pathways by which breast cancer cells can grow and migrate out of the primary tumor to spread to other organs in the b...
Source: Albert Einstein College of Medicine, Bronx, NY, USA.  Jan 01, 2019  4 years ago
Scientists have created a cheaper, faster, reproducible diagnostic technique that has the potential to predict the risk of metastasis in prostate cancer.   For patients who are newly diagnosed, or patients previously treated, the risk of metastasis in prostrate cancer  is a crucial factor of whether to choose conservative management or undergo further treatment. For prostate as we...
Source: University Of Virginia  Dec 19, 2018  4 years ago
Researchers at the University of Virginia School of Medicine have made a discovery about human papillomavirus (HPV) that could lead to new treatments for cervical cancer and other cancers caused by the virus. HPV is responsible for nearly all cases of cervical cancer and 95 percent of anal cancers. It is the most common sexually transmitted disease, infecting more than 600 million people glo...
Source: Newcastle University  Dec 16, 2018  4 years ago
Hope has emerged for patients with a serious type of bone marrow cancer as new research into a therapeutic drug has revealed improved outcomes and survival rates. In the largest study of its kind, researchers at Newcastle University, UK, have led national research into the treatment of patients with newly diagnosed myeloma.   The results, published online today by The Lancet Oncolo...
Source: University of Basel  Dec 13, 2018  4 years ago
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth—this was discovered by researchers from the University of Basel's Biozentrum two years ago. In a follow-up study, recently published in Cell Reports, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply. The widely used...
Source: University of Birmingham  Dec 09, 2018  4 years ago
The  large scale systematic review published in The Cochrane Library as part of a Special Collection of Cochrane Systematic Reviews bringing together a vast  body of research on the accuracy of tests used to diagnose skin cancer. The suite of eleven reviews was led by Dr Jac Dinnes at the University of Birmingham and supported by the Cochrane Skin Group and a team of over 30 researc...
Source: Northwestern University  Dec 08, 2018  4 years ago
An extensive study from Northwestern Medicine psanning over two decades,  reports that Men with inflammatory bowel disease have four to five times higher risk of being diagnosed with prostate cancer. This is the first report to show men with inflammatory bowel disease have higher than average PSA  (prostate-specific antigen) values, and this group also has a significantly higher risk o...
Source: University of Montreal  Dec 07, 2018  4 years ago
A team of researchers at the Institute for Research in Immunology and Cancer (IRIC) at Université de Montréal has demonstrated that a cancer vaccine can work. Not only that, it could become an extremely effective, non-invasive and cost-effective cancer -fighting tool.   The team's work was published yesterday in Science Translational Medicine.The discovery repres...
Source: University of Maryland School of Medicine  Dec 05, 2018  4 years ago
The Institute of Human Virology (IHV) at the University of Maryland School of Medicine (UMSOM) announced today the discovery that DnaK, a protein of the bacterium mycoplasma, interferes with the mycoplasma-infected cell's ability to respond to and repair DNA damage, a known origin of cancer.   Little or no mycoplasma DnaK DNA sequences were found associated with the tumor, which was ful...
Source: The National Centre for Cancer Research, US  Dec 04, 2018  4 years ago
Immunotherapy, the strategy for triggering the patient's own immune system to attack cancer, is proving effective for more tumour types, although to varying degrees. In lung cancer, immunotherapy had proven to extend survival rates for only some variants of the disease. Now, an international clinical trial led by the oncologist Luis Paz-Ares has substantially increased the group of lung cancer...
Source: Tuff University  Dec 04, 2018  4 years ago
A research team led by Tufts University engineers has developed a non-invasive method for detecting bladder cancer that might make screening easier and more accurate than current invasive clinical tests involving visual inspection of bladder. In the first successful use of atomic force microscopy (AFM) for clinical diagnostic purposes, the researchers have been able to identify signature features ...
Source: University Of Alabama at Birmingham  Dec 02, 2018  4 years ago
Preclinical experiments by University of Alabama at Birmingham researchers suggest the cancer drugs vorinostat, belinostat and panobinostat might be repurposed to treat infections caused by human papillomaviruses, or HPVs. HPV infections caused an estimated 266,000 deaths from cervical cancer worldwide in 2012, according to the World Health Organization. Routine screening by Pap smears or HPV D...
Source: University Of Zurich  Nov 30, 2018  4 years ago
Stem cell transplantation is effective against leukemia. In many cases, however, the transferred immune cells of the donor also attack the recipients' healthy tissue—often with fatal consequences. Researchers at the University of Zurich have now identified a molecule that plays a key role in this process. Blocking this molecule could significantly improve the outcome of patients receivin...
Source: Cedars-Sinai Medical Center   Nov 27, 2018  4 years ago
A new study has identified a novel molecular driver of lethal prostate cancer, along with a molecule that could be used to attack it. The findings were made in laboratory mice. If confirmed in humans, they could lead to more effective ways to control certain aggressive types of prostate cancer, the second-leading cause of cancer death for men in the world. Men whose  prostrate cancer tumor...
Source: University of Minnesota  Nov 26, 2018  4 years ago
A new study by University of Minnesota biomedical engineers shows how they stopped cancer cells from moving and spreading, even when the cells changed their movements. The discovery could have a major impact on millions of people undergoing therapies to prevent the spread of cancer within the body. After targeting the "motors" that generate forces in cancer cells to move, the cancer ce...
Source: Cancer Research UK  Nov 22, 2018  4 years ago
Mannose sugar, a nutritional supplement, can both slow tumour growth and enhance the effects of chemotherapy in mice with multiple types of cancer. This lab study is a step towards understanding how mannose could be used to help treat cancer.    The results of the study, which was funded by Cancer Research UK and Worldwide Cancer Research, are published in Nature.   Tumours ...
Source: British Medical Journal  Nov 19, 2018  4 years ago
Based on results of an observational  study published earlier this week in The BMJ, angiotensin-converting-enzyme (ACE) inhibitors were associated with an increased risk of lung cancer, compared with a similar, but distinct type of blood pressure medication known as angiotensin-receptor blockers (ARBs). Researchers evaluated patients from a U.K. primary care database and identified ove...
Source: University Health Network  Nov 15, 2018  4 years ago
Cancer scientists led by principal investigator Dr. Daniel De Carvalho at Princess Margaret Cancer Centre have combined "liquid biopsy", epigenetic alterations and machine learning to develop a blood test to detect and classify cancer at its earliest stages. The findings, published online today in Nature, describe not only a way to detect cancer,  but hold promise of bei...
SOURCE: BAYLOR COLLEGE OF MEDICINE  Nov 13, 2018  4 years ago
Uncovering a novel mechanism that promotes growth of breast cancer bone metastasis has revealed a potential Achilles' heel for these cancer cells. Reported in the journal Cancer Cell, the study shows that interfering with this mechanism can reduce the risk of relapses in animal models. "Metastasis is the dissemination of cancer cells from the original tumor location to other organ...
Source: University Of Minnesota  Nov 13, 2018  4 years ago
Researchers from the University of Minnesota, the Howard Hughes Medical Institute, and the University of Toronto have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis—more commonly known as mono or the "kissing disease"—that infects millions of people around the globe each...
Source: University of Edinburgh  Nov 08, 2018  4 years ago
A pioneering technique designed to spot differences between immune cells in tumours could speed the development of cancer treatments, research suggests.   Scientists say the approach could be used to help doctors choose the best treatments for individual patients and predict which tumours are likely to respond to a particular therapy. It could help target the use of immunotherapy -- a new ...
Source: Brunel University London  Nov 01, 2018  4 years ago
A shift in glucose metabolism hails progression from liver cirrhosis to liver cancer, finds a new study   Liver cancer is the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. Most cases are discovered too late for a cure -- but now a study offers hope of early detection, and targets for new treatments. Published in Frontiers in Cell and De...
Source: University of Otago  Nov 01, 2018  4 years ago
University of Otago researchers have used high-resolution electron microscopy images to reveal how an anti-cancer virus interacts with tumor cells, increasing its potential to save lives. Seneca Valley Virus (SVV), a newly discovered virus which infects cancer cells but not normal tissue, has become a main research project in the New Zealand laboratory of Dr Mihnea Bostina, Academic Director of ...
Source: National News Bureau Of Thailand  Oct 25, 2018  4 years ago
Chulalongkorn University’s faculty of medical science has successfully produced a cancer treatment of equivalent efficacy to internationally available drugs in a test tube, and has committed to developing it over the next eight years to serve as an affordable choice for Thai citizens.  Dr. Trairak Pisitkul,Head of Chulalongkorn University’s Systems Biology Center  The rese...
Source: Journal of Controlled Release  Oct 24, 2018  4 years ago
Houston Methodist scientists have developed a nanodevice to deliver immunotherapy without side effects to treat triple-negative breast cancer. Inserted straight into a tumor, this nanofluidic seed makes it possible to deliver a one-time, sustained-release dose that would eliminate the need for patients to undergo several IV treatments over time.   MAGE: SMALLER THAN A GRAIN OF RICE, ...
Source: AstraZeneca  Oct 11, 2018  4 years ago
Metastatic breast cancer is cancer that has advanced and spread beyond the breast and regional lymph nodes to other parts of the body. Around 20–50% of patients diagnosed with primary breast cancer will develop metastatic disease and up to 19% of patients with breast cancer already had metastatic disease when they were first diagnosed. Treatments for metastatic breast cancer aim to allevia...
Source: Cincinnati Children's Hospital Medical Center  Oct 02, 2018  4 years ago
Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH diagnosis doesn't obscure possible underlying cancers. Because HLH is dangerously aggressive in its progression and attack on vital organs—often causing death—doctors frequently pursue immed...
Source: American Association for Cancer Research  Oct 01, 2018  4 years ago
Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial. Among 11 evaluable patients who had received more than the lowest dose of the vaccine, six (54 percent) had clinical benefit. One patient ...
Source:University of California, Los Angeles  Sep 18, 2018  4 years ago
Scientists have long known that circulating tumor cells, rare cancer cells that are released into the bloodstream, have the potential to provide vital information about a person's specific cancer. But until now, they have been unable to reliably access information on how these cells behave. UCLA researchers have created a quick and effective mechanism to measure how these cells perform functio...

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