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Source: COVID-19 Disease  Feb 17, 2021  3 years, 2 months, 21 hours, 1 minute ago

French Study Reveals That COVID-19 Causes Potentially Dangerous Eye Abnormalities Such As The Formation Of Nodules In The Macular Region!

French Study Reveals That COVID-19 Causes Potentially Dangerous Eye Abnormalities Such As The Formation Of Nodules In The Macular Region!
Source: COVID-19 Disease  Feb 17, 2021  3 years, 2 months, 21 hours, 1 minute ago
A new French study by researchers from the Foundation Adolphe de Rothschild Hospital in Paris have found that COVID-19 causes a potentially dangerous eye condition in a segment of patients that are severely infected in which the formation of nodules are observed in the macular regions of the eyes.


 
The study findings report 9 patients (1/9 [11%] woman and 8/9 [89%] men, mean age 56 ± 13 years) with globe MRI abnormalities obtained from a multicenter cohort of 129 patients presenting with severe COVID-19 disease from March 4th to May 1st, 2020. 9/129 (7%) patients had one or several FLAIR-WI hyperintense nodules of the posterior pole of the globe. All patients had nodules in the macular region, 8/9 (89%) had bilateral nodules, 2/9 (22%) had nodules outside the macular region. Screening of these patients might improve the management of potentially severe ophthalmological manifestations of the virus.
 
The study findings were published in the peer reviewed journal: Radiology.
https://pubs.rsna.org/doi/10.1148/radiol.2021204394
 
The study team utilizing MRI had found significant abnormalities in the eyes of certain individuals with severe COVID-19.
 
The research findings support the need for eye screening in these patients to provide appropriate treatment and management of potentially severe ophthalmological manifestations of COVID-19.
 
To date, the COVID-19 pandemic has affected more than 109 million people since it began early in 2020.
 
Although the SARS-CoV-2 coronavirus primarily attacks the lungs, it has been linked with eye abnormalities like conjunctivitis, also known as pink eye, and retinopathy, a disease of the retina that can result in a loss of vision.
 
Ocular or eye abnormalities visible on MRI exams have been reported but there is limited research on the nature and frequency of these abnormalities.
 
In order to find out more, the French Society of Neuroradiology (SFNR) initiated a study of 129 patients with severe COVID-19 who underwent brain MRI.
 
Interestingly of the 129 patients, nine (7%) had abnormal MRI findings of the globe, or eyeball. The MRI scans showed one or more nodules in the back part, or posterior pole, of the eyeball. Eight of the nine patients had spent time in the intensive care unit (ICU) for COVID-19.
 
Lead author Dr Augustin Lecler, M.D., Ph.D., associate professor at the University of Paris and neuroradiologist from the Department of Neuroradiology at the Foundation Adolphe de Rothschild Hospital in Paris told Thailand Medical News, "We showed that a few patients with severe COVID-19 from the French COVID-19 cohort had one or several nodules of the posterior pole of the globe. This is the first time these findings have been described using MRI."
 
Importantly all nine patients had nodules in the macular region, the area in the back of the eye responsible for our central vision. Eight had nodules in both eyes.
 
The study findings suggest that screening should be considered in all patients with severe COVID-19 to detect these nodules. In clinical practice, this screening could include dedicated explor ation of the eyes with high-resolution MRI, the researchers said.
 
Further recommended exams include fundoscopy, which uses a magnifying lens and a light to check the back of the inside of the eye, and optical coherence tomography, a noninvasive test that provides a 3-D picture of the structure of the eye.
 
The study team noted that severe eye prob