Canadian Scientists Discover Phytochemical Thykamine That Has Stronger Anti-Inflammatory Effects Than Common Drugs!
Nikhil Prasad Fact checked by:Thailand Medical News Team Dec 10, 2025 1 day, 6 hours, 2 minutes ago
Medical News: A Natural Compound Outperforms Steroids in Lab Tests
Scientists from the University of Toronto, Université Laval, and McGill University have discovered that Thykamine, a newly-identified phytochemical made from spinach thylakoid membranes (Spinach thylakoid membranes are the intricate, folded internal membranes within spinach chloroplasts where the light-dependent reactions of photosynthesis occur), shows stronger anti-inflammatory effects than several well-known corticosteroids and non-steroidal treatments. This new compound may offer safer and more effective treatment options for people suffering from inflammatory diseases such as eczema, ulcerative colitis, rheumatoid arthritis, and even severe COVID-19.
Thykamine from spinach outperforms many steroids & shows promise for safer treatment of inflammation related diseases
According to this
Medical News report, the researchers compared Thykamine to six popular drugs including prednisone, hydrocortisone, betamethasone, clobetasol, crisaborole, and pimecrolimus. They tested how well each drug could reduce the levels of four key inflammatory substances known as chemokines—MCP-1, MIP-1α, MIP-1β, and RANTES. These substances are often found at high levels in patients with chronic conditions and are responsible for attracting immune cells that cause inflammation.
Thykamine Outperforms Six Common Treatments
In lab experiments using immune cells stimulated with bacterial components, Thykamine consistently outperformed or matched the effectiveness of all the tested drugs in reducing the chemokines. For three of the chemokines—MCP-1, MIP-1α, and MIP-1β—Thykamine showed significantly higher potency than all other drugs. It also performed well in lowering RANTES, showing better results than most drugs except crisaborole and prednisone, which were only stronger at the highest concentrations.
What makes Thykamine especially interesting is that its effect was strong even at lower doses, and unlike some of the other medications tested, it did not show any signs of harming the cells.
A Multi Target Botanical Compound with Fewer Risks
Thykamine’s power comes from its unique combination of natural plant-based ingredients like galactolipids, chlorophylls, and antioxidant enzymes. It doesn’t target just one inflammatory molecule like many synthetic drugs do, but instead works on several pathways. This broad approach could make it more effective for people with chronic diseases, while also reducing the risk of side effects or treatment resistance that often comes with long-term use of steroids.
Past clinical trials have already shown that Thykamine is safe and helpful in treating mild-to-moderate ulcerative colitis and atopic dermatitis. These latest lab findings strengthen the case for more research into its use for a wider range of conditions, especially those where inflammation plays a central role.
Thykamine c
ould represent a new class of anti-inflammatory medication that’s both effective and gentler on the body. As drug resistance and steroid side effects continue to challenge doctors and patients, this plant-based compound may soon offer an important new alternative in medical care.
The study findings were published in the peer reviewed journal: Biomedicines.
https://www.mdpi.com/2227-9059/13/12/2938
For the latest on Herbs and Phytochemicals and Anti-Inflammatory solutions, keep on logging to Thailand
Medical News.
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https://www.thailandmedical.news/articles/herbs-and-phytochemicals
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