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Source: Thailand Medical News  Dec 09, 2019  4 years, 9 months, 3 weeks, 5 days, 3 hours, 36 minutes ago

Study Shows That Even Small Amounts Of Alcohol Consumption Increases Risk Of Cancer In Japan

Study Shows That Even Small Amounts Of Alcohol Consumption Increases Risk Of Cancer In Japan
Source: Thailand Medical News  Dec 09, 2019  4 years, 9 months, 3 weeks, 5 days, 3 hours, 36 minutes ago
In a joint study conducted by researchers from Harvard University and University of Tokyo, it was found that even light to moderate alcohol consumption was associated with elevated cancer risks in Japan. In the study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the overall cancer risk appeared to be the lowest at zero alcohol consumption.



In the past, certain studies have linked limited alcohol consumption to increase risks of certain types of cancer, but this is the first study to indicate that even light to moderate consumption is associated with a higher risk of cancer overall.

To research the issue in Japan, Masayoshi Zaitsu, MD, PhD, of The University of Tokyo and the Harvard T.H. Chan School of Public Health, and his colleagues examined 2005-2016 information from 33 general hospitals throughout Japan. The team examined clinical data on 63,232 patients with cancer and 63,232 controls matched for sex, age, hospital admission date, and admitting hospital. All participants reported their average daily amount of standardized alcohol units and the duration of drinking. (One standardized drink containing 23 grams of ethanol was equivalent to one 180-milliliter cup (6 ounces) of Japanese sake, one 500-milliliter bottle (17 ounces) of beer, one 180-milliliter glass (6 ounces) of wine, or one 60-milliliter cup (2 ounces) of whiskey.

In all, cancer risk appeared to be the lowest at zero alcohol consumption, and there was an almost linear association between cancer risk and alcohol consumption. The association suggested that a light level of drinking at a 10-drink-year point (for example, one drink per day for 10 years or two drinks per day for five years) would increase overall cancer risk by five percent. Those who drank two or fewer drinks per day had an elevated cancer risk regardless of how long they had consumed alcohol. Also, analyses classified by sex, drinking/smoking behaviors, and occupational class mostly showed the same patterns.

The increased risk appeared to be explained by alcohol-related cancer risk across relatively common sites, including the colorectum, stomach, breast, prostate, and esophagus.

Dr. Zaitsu told Thailand Medical News via a phone interview, "In Japan, the primary cause of death is cancer,". "Given the current burden of overall cancer incidence, we should further encourage promoting public education about alcohol-related cancer risk."

Reference: "Light to moderate amount of lifetime alcohol consumption and risk of cancer in Japan." Masayoshi Zaitsu, Takumi Takeuchi, Yasuki Kobayashi, and Ichir o Kawachi. CANCER; Published Online: December 9, 2019 (DOI: 10.1002/cncr.32590).  https://doi.wiley.com/10.1002/cncr.32590

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