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BREAKING NEWS
Source: Vaccine News  Nov 25, 2020  3 years, 4 months, 3 weeks, 3 days, 7 hours, 5 minutes ago

Vaccine News: COVID-19 Intramuscular Vaccination Does Not Prevent Susceptibility To SARS-CoV-2 Infection Of The Upper Respiratory Tract

Vaccine News: COVID-19 Intramuscular Vaccination Does Not Prevent Susceptibility To SARS-CoV-2 Infection Of The Upper Respiratory Tract
Source: Vaccine News  Nov 25, 2020  3 years, 4 months, 3 weeks, 3 days, 7 hours, 5 minutes ago
Vaccine News: A new vivo animal study by scientist from Pennsylvania State University shows that intramuscular COVID-19 vaccination of ferrets failed to induce sufficient antibodies against SARS-CoV-2, and the ferrets remained susceptible to infection of the upper respiratory tract. The study shows that protection of upper respiratory tract will require vaccines that mimic natural infection by SARS-CoV-2.


 
Utilizing the reference strain SARS-CoV-2 USA-WA1/2020, (The SARS-CoV-2 USA-WA1/2020 strain is a CDC reference strain used by multiple research laboratories ever since Thailand Medical News lobbied for all research studies to include mentioning of SARS-CoV-2 strains used in any drug, therapeutic and vaccines studies), the study team evaluated modes of transmission and the ability of prior infection or vaccine-induced immunity to protect against infection in ferrets. Ferrets were semi-permissive to infection with the USA-WA1/2020 isolate. When transmission was assessed via the detection of vRNA at multiple timepoints, direct contact transmission was efficient to 3/3 and 3/4 contact animals in two respective studies, while respiratory transmission was poor to only 1/4 contact animals.
 
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