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BREAKING NEWS
Source: UT Southwestern Medical Center  Mar 25, 2019  5 years, 3 weeks, 5 days, 8 hours, 44 minutes ago

New protocol to reduce inflammation.

New protocol to reduce inflammation.
Source: UT Southwestern Medical Center  Mar 25, 2019  5 years, 3 weeks, 5 days, 8 hours, 44 minutes ago

UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection.


new protocol

The proteins -- the transcription factors SIX1 and SIX2 -- activate cellular pathways required for fetal development and later switch to a new role in which they repress these pathways in adult immune system cells. 

"This work provides insight into the molecular components required to limit tissue damage associated with uncontrolled inflammation, such as in septic shock, and reveals how cancer cells may suppress the innate immune system during tumor genesis," said Dr. Neal Alto, Professor of Microbiology at UT Southweste