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Latests Medical News from around the world and also Thailand, bringing you updates, discoveries, studies and findings on various aspects and diseases in the medical world. Most of these articles are not only meant for Doctors In Thailand or Hospitals In Thailand but also for any patients or health conscious individuals wanting to know more.
Source: Baylor College of Medicine  Jan 06, 2019  5 years ago
Fungal infections are emerging as a major medical challenge, and a team led by researchers at Baylor College of Medicine has developed a mouse model to study the short-term consequences of fungal infection in the brain. The researchers report in the journal Nature Communications the unexpected finding that the common yeast Candida albicans, a type of fungus, can cross the blood-b...
Source: Massachusetts Institute of Technology  Jan 06, 2019  5 years ago
Messenger RNA, which can induce cells to produce therapeutic proteins, holds great promise for treating a variety of diseases. The biggest obstacle to this approach so far has been finding safe and efficient ways to deliver mRNA molecules to the target cells. In an advance that could lead to new treatments for lung disease, MIT researchers have now designed an inhalable form of mRNA. This aerosol...
Source: University Of Zurich  Jan 01, 2019  5 years ago
Cystic fibrosis is a severe hereditary disease of the lung, for which there is currently no cure. The underlying cause of the disease is a malfunction of the chloride channel CFTR, which prevents the secretion of chloride in certain body cells. This leads to dehydration of the mucus layer in the lung. A promising approach for treating cystic fibrosis is the activation of the calcium-activated chlo...
Source: Osaka University  Dec 30, 2018  5 years ago
A team of researchers led by Osaka University examined the dissemination of colistin-resistant bacteria among residents of rural communities in Vietnam to find that the prevalence of colistin-resistant Escherichia coli (CR-E) in the intestines was extremely high, at about 70 percent. This Escherichia coli (E. coli) is a non-pathogenic bacterium, so the residents have no symptom...
Source: University of Southern California  Dec 28, 2018  5 years ago
A new study by Keck School of Medicine of USC researchers shows there's yet another reason to avoid a high fat, high cholesterol diet: It can trigger changes in the immune system that lead to a serious form of non-alcoholic fatty liver disease (NAFLD) known as non-alcoholic steatohepatitis (NASH). NAFLD is one of the most common causes of liver disease in the United States, and an estimated 2...
Source: University Of Toronto  Dec 26, 2018  5 years ago
Letrozole was found to damage normal function in the hippocampus of monkeys The animals also showed anxiety and hot flashes after four weeks of treatment Side effects like fatigue are experienced by up to 30% of women on the drug   A drug commonly given out  to breast-cancer patients may affect their brain function and memory, research suggests.Letrozole is primarily used to treat b...
Source: Dallas Morning News (Anna Kuchment)  Dec 25, 2018  5 years ago
Medical researchers fear that more children will develop paralysis from a mysterious polio like illness that has struck every two years since 2014. The condition, known as acute flaccid myelitis, or AFM, is rare and has reached its peak for 2018. It will likely continue to fade as winter approaches. But many believe it will be back.   D68 Enterovirus "AFM is here, and it doesn't se...
Source: University Of Virginia School Of Medicine  Dec 23, 2018  5 years ago
A group of genes called SLCs that has been largely ignored by scientists could play critical roles in atherosclerosis (hardening of the arteries), inflammation, and likely obesity and other metabolic diseases, new research suggests.The discovery was made by researchers at the University of Virginia School of Medicine in the context of how our bodies recognize and remove dying cells. SLC Gene &nb...
Source: St. Jude Children’s Research Hospital  Dec 22, 2018  5 years ago
St. Jude Children's Research Hospital scientists have discovered a subset of helper T cells that may help to redefine understanding and treatment of chronic, debilitating inflammatory disorders. The study focused on a family of helper T cells called Th17 cells. Th17 cells help to launch the immune response against fungal infection and other threats. These cells can also fuel the destructive i...
Source: Yale University  Dec 21, 2018  5 years ago
In a new study, Yale Cancer Center (YCC) scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caution should be exercised as we continue to better understand the biology of these new therapeutic targets. The findings are published today in the journal Cell. Researchers around the world have been racing to create therapies that unleash th...
Source: Columbia University Irving Medical Center  Dec 20, 2018  5 years ago
In a phase three clinical trial, a drug called sorafenib stopped progression of desmoid tumors for two years in 80 percent of patients who completed treatment, a significant increase in progression-free survival compared with placebo. (Progression-free survival is the length of time a patient lives without worsening of the disease). There is no standard of care for patients with desmo...
Source: Rutgers University  Dec 15, 2018  5 years ago
Scientists have taken an important step toward the goal of making diseased hearts heal themselves -- a new model that would reduce the need for bypass surgery, heart transplants or artificial pumping devices. A team of Rutgers scientists, including Leonard Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves -- a new model that would reduce ...
Source: Harvard Medical School  Dec 14, 2018  5 years ago
The elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long known that a weakened immune system is to blame but the exact mechanisms behind this lagging immunity have remained largely unknown. Now research led by investigators at Harvard Medical School suggests that weakened metabolism of immune T cells may be p...
Source: Thai PBS World  Dec 13, 2018  5 years ago
Vegetables and fruits found in lunches for students under the government-sponsored lunch programme are almost 100 percent contaminated with pesticides and 99 percent of the urine samples from students and teachers in four provinces were tested with organophosphate, a deadly toxic pesticide that attacks nervous system. The above alarming findings were the result of a research jointly conducted by...
Source: University of Basel  Dec 13, 2018  5 years ago
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth—this was discovered by researchers from the University of Basel's Biozentrum two years ago. In a follow-up study, recently published in Cell Reports, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply. The widely used...
Source: Oswaldo Cruz Foundation, Brazil  Dec 12, 2018  5 years ago
Current treatment options for the parasitic disease leishmaniasis are largely ineffective, expensive, and tend to be plagued by resistant parasites and side effects. Now, researchers reporting in PLOS Neglected Tropical Diseases have showed that a natural flavonoid is effective at treating Leishmania amazonensis infections. Leishmaniasis is endemic to 98 countries and affect...
Source: University of Glasgow  Dec 11, 2018  5 years ago
Kidney dialysis can cause short-term 'cerebral stunning' and may be associated with progressive brain injury in those who receive the treatment for many years. For many patients with kidney failure awaiting a kidney transplant or those not suitable for a transplant, dialysis is a life-saving treatment. New research, led by the University of Glasgow and published today in the Journal Ame...
Source: TMN  Dec 10, 2018  5 years ago
 CAP or Community-acquired pneumonia disproportionately affects older people, with high rates of morbidity and mortality among the elderly. Although pneumococcal vaccines are routinely recommended for this population, fewer than 40% of adults age 60 and older get vaccinated. Thus, antibiotics are key to treating CAP in the elderly—and the earlier that antibiotic therapy starts, the bett...
Source: University of Birmingham  Dec 09, 2018  5 years ago
The  large scale systematic review published in The Cochrane Library as part of a Special Collection of Cochrane Systematic Reviews bringing together a vast  body of research on the accuracy of tests used to diagnose skin cancer. The suite of eleven reviews was led by Dr Jac Dinnes at the University of Birmingham and supported by the Cochrane Skin Group and a team of over 30 researc...
Source: University of Montreal  Dec 07, 2018  5 years ago
A team of researchers at the Institute for Research in Immunology and Cancer (IRIC) at Université de Montréal has demonstrated that a cancer vaccine can work. Not only that, it could become an extremely effective, non-invasive and cost-effective cancer -fighting tool.   The team's work was published yesterday in Science Translational Medicine.The discovery repres...
Source: University of Tennessee Health Science Center, US.  Dec 06, 2018  5 years ago
Scientists have identified a key player in blood pressure regulation and have shown that switching it off reduces blood pressure in mice.Their study ends much uncertainty about the contribution this molecule makes to high blood pressure and could lead to the development of new drugs. High blood pressure affects millions worldwide and is a leading cause of heart attack and stroke.   Blo...
Source: University of Maryland School of Medicine  Dec 05, 2018  5 years ago
The Institute of Human Virology (IHV) at the University of Maryland School of Medicine (UMSOM) announced today the discovery that DnaK, a protein of the bacterium mycoplasma, interferes with the mycoplasma-infected cell's ability to respond to and repair DNA damage, a known origin of cancer.   Little or no mycoplasma DnaK DNA sequences were found associated with the tumor, which was ful...
Source: Tuff University  Dec 04, 2018  5 years ago
A research team led by Tufts University engineers has developed a non-invasive method for detecting bladder cancer that might make screening easier and more accurate than current invasive clinical tests involving visual inspection of bladder. In the first successful use of atomic force microscopy (AFM) for clinical diagnostic purposes, the researchers have been able to identify signature features ...
Source: University of Chicago Medical Center  Dec 03, 2018  5 years ago
An international phase-2 trial of a CAR-T cell therapy—to be published on-line Dec. 1 in the New England Journal of Medicine (and presented at the ASH annual meeting in San Diego)—found that 52 percent of patients responded favorably to the therapy; 40 percent had a complete response and 12 percent had a partial response. One year later, 65 percent percent of those patients w...
Source: University Of Alabama at Birmingham  Dec 02, 2018  6 years ago
Preclinical experiments by University of Alabama at Birmingham researchers suggest the cancer drugs vorinostat, belinostat and panobinostat might be repurposed to treat infections caused by human papillomaviruses, or HPVs. HPV infections caused an estimated 266,000 deaths from cervical cancer worldwide in 2012, according to the World Health Organization. Routine screening by Pap smears or HPV D...
Source: University Of Montreal  Dec 01, 2018  6 years ago
Of the 50 million people around the world infected with HIV, less than one per cent have immune systems strong enough to suppress the virus for extended periods of time. These special immune systems are known as "elite controllers." But how do they actually fight HIV? Canadian scientists think they've found an important clue. TRIM5 Alpha protein Working in collaboration with a team...
Source: University Of Zurich  Nov 30, 2018  6 years ago
Stem cell transplantation is effective against leukemia. In many cases, however, the transferred immune cells of the donor also attack the recipients' healthy tissue—often with fatal consequences. Researchers at the University of Zurich have now identified a molecule that plays a key role in this process. Blocking this molecule could significantly improve the outcome of patients receivin...
Source: Northwell Health’s Feinstein Institute for Medical Research  Nov 29, 2018  6 years ago
Scientists have uncovered that an emerging gene therapy for Parkinson's disease creates new circuits in the brain associated with improved motor movement. These findings, published today in Science Translational Medicine by Feinstein Institute for Medical Research Professor David Eidelberg, MD, and his team, explain the therapeutic mechanisms involved in the emerging Parkinson's ...
Source: Johns Hopkins University Of Medicine  Nov 28, 2018  6 years ago
Researchers at Johns Hopkins have identified two patients with HIV whose immune cells behave differently than others with the virus and actually appear to help control viral load even years after infection. Moreover, both patients carry large amounts of virus in infected cells, but show no viral load in blood tests. While based on small numbers, the data suggest that long-term viral remission migh...
Source: Cedars-Sinai Medical Center   Nov 27, 2018  6 years ago
A new study has identified a novel molecular driver of lethal prostate cancer, along with a molecule that could be used to attack it. The findings were made in laboratory mice. If confirmed in humans, they could lead to more effective ways to control certain aggressive types of prostate cancer, the second-leading cause of cancer death for men in the world. Men whose  prostrate cancer tumor...
Source: University of Minnesota  Nov 26, 2018  6 years ago
A new study by University of Minnesota biomedical engineers shows how they stopped cancer cells from moving and spreading, even when the cells changed their movements. The discovery could have a major impact on millions of people undergoing therapies to prevent the spread of cancer within the body. After targeting the "motors" that generate forces in cancer cells to move, the cancer ce...
Source: VIB (the Flanders Institute for Biotechnology)  Nov 25, 2018  6 years ago
Scientists from the VIB-UGent Center for Inflammation Research identified the mechanisms by which the bacterial pathogen Clostridium difficile kills intestinal epithelial cells (IECs), thus destroying the protective mucosal barrier of the intestinal tract. The researchers demonstrate the physiological relevance of this process during infection and have published their findings in Nature Commu...
Source: University Of Manchester  Nov 23, 2018  6 years ago
An international study lead by University of Manchester scientists has discovered the identity of genes that predispose people to chronic kidney disease. The discovery is a major advance in understanding of the significantly under-diagnosed disorder which, if left undetected, can lead to failing kidneys that need dialysis or kidney transplantation.    The discovery of 35 kidney &n...
Source: Ministry Of Foreign Affairs (Thailand)  Nov 22, 2018  6 years ago
 On 21 November 2018, the Prince Mahidol Award Foundation under the Royal Patronage (PMAF) held a joint press conference at Siriraj Hospital, Bangkok, to announce the 27th Prince Mahidol Laureates for 2018 in the field of Medicine and Public Health. Ms. Busadee Santipitaks, Director-General of the Department of Information, Ministry of Foreign Affairs of Thailand, in the capacity of the ...
Source: Cancer Research UK  Nov 22, 2018  6 years ago
Mannose sugar, a nutritional supplement, can both slow tumour growth and enhance the effects of chemotherapy in mice with multiple types of cancer. This lab study is a step towards understanding how mannose could be used to help treat cancer.    The results of the study, which was funded by Cancer Research UK and Worldwide Cancer Research, are published in Nature.   Tumours ...
University Of Queensland  Nov 21, 2018  6 years ago
A world-first clinical trial of a new cellular immunotherapy for multiple sclerosis (MS) has improved symptoms and quality of life for the majority of patients. This electron microscopic image of two Epstein Barr Virus virions (viral particles) shows round capsids—protein-encased genetic material—loosely surrounded by the membrane envelope. Credit: DOI: 10.1371/journal.pbio.0030430.g...
Source: University Of Leeds   Nov 20, 2018  6 years ago
Both aspirin and a purified omega-3, called EPA, reduce the number of pre-cancerous polyps in patients found to be at high risk of developing bowel cancer, according to new research. A clinical trial, led by the University of Leeds, found that both aspirin and EPA reduced the number of bowel polyps in patients one year on from a screening colonoscopy (large bowel camera test), although they did ...
Source: British Medical Journal  Nov 19, 2018  6 years ago
Based on results of an observational  study published earlier this week in The BMJ, angiotensin-converting-enzyme (ACE) inhibitors were associated with an increased risk of lung cancer, compared with a similar, but distinct type of blood pressure medication known as angiotensin-receptor blockers (ARBs). Researchers evaluated patients from a U.K. primary care database and identified ove...
Source: Karolinska Institutet  Nov 16, 2018  6 years ago
A multidisciplinary team of researchers led from Karolinska Institutet in Sweden have developed an anti-inflammatory drug molecule with a new mechanism of action. By inhibiting a certain protein, the researchers were able to reduce the signals that trigger an inflammation. The study is published in Science and was done in collaboration with the University of Texas Medical Branch, Uppsala...
Source: TMN Staff Writer  Nov 15, 2018  6 years ago
Yet another blood pressure drug has been recalled because of fears of impurities added by a lab in China. Drug company Sandoz says it has recalled one lot of losartan  potassium hydrochlorothiazide tablets. The impurity, known as NDEA, was found in the drug’s key ingredient made by Zhejiang Huahai Pharmaceutical Co. in China. NDEA is found naturally in certain foods, drinking wa...
Source: Georgetown University Medical Center   Nov 14, 2018  6 years ago
A defining feature of Parkinson's disease is the clumps of alpha-synuclein protein that accumulate in the brain's motor control area, destroying dopamine-producing neurons. Natural processes can't clear these clusters, known as Lewy bodies, and no one has demonstrated how to stop the build up as well as breakdown of the clumps—until perhaps now.   A team of neurologists at...
Source: University Of Minnesota  Nov 13, 2018  6 years ago
Researchers from the University of Minnesota, the Howard Hughes Medical Institute, and the University of Toronto have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis—more commonly known as mono or the "kissing disease"—that infects millions of people around the globe each...
Source: NIH/National Institute of Environmental Health Sciences(USA)  Nov 11, 2018  6 years ago
The National Toxicology Program (NTP) concluded there is clear evidence that male rats exposed to high levels of radio frequency radiation (RFR) like that used in 2G , 3G and 4G cell phones developed cancerous heart tumors, according to final reports released today. There was also some evidence of tumors in the brain and adrenal gland of exposed male rats. For female rats, and male and female mice...
Source: Brigham and Women’s Hospital.  Nov 10, 2018  6 years ago
The management of human immunodeficiency virus 1 (HIV), an autoimmune disorder that cripples the immune system by attacking healthy cells, remains a major global health challenge in developing countries that lack infrastructure and trained medical professionals. Investigators from Brigham and Women's Hospital have designed a portable and affordable mobile diagnostic tool, utilizing a cellphone...
Source: University of Edinburgh  Nov 08, 2018  6 years ago
A pioneering technique designed to spot differences between immune cells in tumours could speed the development of cancer treatments, research suggests.   Scientists say the approach could be used to help doctors choose the best treatments for individual patients and predict which tumours are likely to respond to a particular therapy. It could help target the use of immunotherapy -- a new ...
Source: Medical University Of South Carolina  Nov 07, 2018  6 years ago
Mitochondria are responsible for supplying the cell with energy in the form of ATP through oxidative phosphorylation. There is a group of rare, autosomal recessive disorders, known as Mitochondrial DNA Depletion Syndromes (MTDPS), which causes a significant reduction in mitochondrial DNA (mtDNA) and ATP production. There is no treatment for MTDPS, and it is typically fatal during infancy as a resu...
Source: University of Otago  Nov 01, 2018  6 years ago
University of Otago researchers have used high-resolution electron microscopy images to reveal how an anti-cancer virus interacts with tumor cells, increasing its potential to save lives. Seneca Valley Virus (SVV), a newly discovered virus which infects cancer cells but not normal tissue, has become a main research project in the New Zealand laboratory of Dr Mihnea Bostina, Academic Director of ...
Source: National News Bureau Of Thailand  Oct 25, 2018  6 years ago
Chulalongkorn University’s faculty of medical science has successfully produced a cancer treatment of equivalent efficacy to internationally available drugs in a test tube, and has committed to developing it over the next eight years to serve as an affordable choice for Thai citizens.  Dr. Trairak Pisitkul,Head of Chulalongkorn University’s Systems Biology Center  The rese...
Source: University Of Vienna  Oct 24, 2018  6 years ago
Researchers monitored a group of participants from 8 countries across the world with results showing that every single stool sample tested positive for the presence of microplastic and up to 9 different plastic types were identified. Microplastics have been found in the human food chain as particles made of polypropylene (PP), polyethylene-terephthalate (PET) and others were detected in human sto...
Source: Stanford University Medical Center  Oct 16, 2018  6 years ago
The most common source of a bloodstream infection acquired during a hospital stay is not a nurse's or doctor's dirty hands, or another patient's sneeze or visitor's cough, but the patient's own gut, Stanford University School of Medicine investigators have found.    Most patients who spend longer than a few days in a hospital acquire infections. In particular, upward ...
Source: Cincinnati Children's Hospital Medical Center  Oct 02, 2018  6 years ago
Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH diagnosis doesn't obscure possible underlying cancers. Because HLH is dangerously aggressive in its progression and attack on vital organs—often causing death—doctors frequently pursue immed...
Source:University of Illinois at Chicago  Sep 18, 2018  6 years ago
Clinicians, scientists and public health professionals should proudly "declare victory" in their efforts to extend the human lifespan to its very limits, according to University of Illinois at Chicago epidemiologist S. Jay Olshansky. In an article published in the Journal of the American Medical Association, Olshansky writes that the focus should shift to compressing the "red ...
Source: Case Western Reserve University  Aug 28, 2018  6 years ago
Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease (IBD), and arthritis.       The findings, published in Science Immunology, identify a chemical that potently inhibits inflammatory cell death. Cells often perforate their own membranes...
Source: Walter and Eliza Hall Institute of Medical Research  Aug 08, 2018  6 years ago
New anti-cancer drugs put cancers to sleep—permanently In a world first, Melbourne scientists have discovered a new type of anti-cancer drug that can put cancer cells into a permanent sleep, without the harmful side-effects caused by conventional cancer therapies.   Published today in the journal Nature, the research reveals the first class of anti-cancer drugs that work...
Source: American Heart Association  Jul 19, 2018  6 years ago
Stem cells from umbilical cords may improve heart function and symptoms. Stem cells from umbilical cords show promise as a treatment for heart failure, based on a recent study published in the American Heart Association journal Circulation Research.   Known as the RIMECARD trial, this study tested stem cell therapy in 30 patients living with chronic heart failure. The goal was t...

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