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Source: HPV  May 21, 2020  3 years, 10 months, 3 weeks, 6 days, 20 hours, 44 minutes ago

MUST READ! HPV: Australian Researchers Develops New Saliva Test To Diagnose Patients With Oral Cancer Caused By HPV

MUST READ! HPV: Australian Researchers Develops New Saliva Test To Diagnose Patients With Oral Cancer Caused By HPV
Source: HPV  May 21, 2020  3 years, 10 months, 3 weeks, 6 days, 20 hours, 44 minutes ago
HPV: Medical researchers from Queensland University Of Technology-Australia have developed the world’s first saliva test for detecting oropharyngeal cancer caused by human papillomavirus-16 or HPV-16 .


 
The new diagnostics is able to detect such cancer even in asymptomatic individuals.
 
The research findings and the development of the new saliva based diagnostics has been published in the journal Frontiers in Oncology. https://www.frontiersin.org/articles/10.3389/fonc.2020.00408/full
 
The Australian researchers suggest the new tests could be utilized for testing larger cohort of healthy asymptomatic individuals and become routine widespread screening for HPV-16, the main factor behind skyrocketing rates of oropharyngeal cancer.
 
Dr Chamindie Punyadeera, senior author of the study from Queensland University of Technology in Brisbane told Thailand Medical News,  "It is critical to detect such oral cancers early as oropharyngeal squamous cells carcinoma often presents at a late stage with patients which make treatments difficult.”
 
She added, "This research for the first time provides a solid scientific foundation to initiate a screening trial in high-risk individuals to detect HPV-driven oropharyngeal cancer. Saliva testing could be broadly implemented and utilized in a screening triasl in the future."
 
The novel saliva test was developed by Dr Punyadeera and first author Dr Kai Dun Tang also from Queensland University of Technology.
 
The saliva based diagnostics is administered as an oral rinse: the individual swishes a saline solution around in his or her mouth for a minute or two, and then spits the sample into a tube.
 
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The new saliva diagnostic was being scrutinized in an ongoing HPV-16 DNA prevalence study, which involved 650 healthy participants being tested for oral HPV-16 DNA.
 
The researchers said, "Of these, 3 have been identified to have persistent oral HPV-16 DNA infection."
 
The researchers approached these three participants and one middle-aged male who had been consistently HPV-16 DNA positive for a period of 36 months  and whose HPV-16 viral load had been steadily rising over time, was invited to attend an ear, nose and throat clinic for assessment.
 
The researchers said, "Fortunately, initial clinical examination of the oropharynx including palpation and white light revealed no significant abnormalities,"
 
Dr Punyadeera explained that