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Sourec: COVID-19 News  Aug 03, 2020  3 years, 8 months, 2 weeks, 15 hours, 6 minutes ago

BREAKING! COVID-19 News: Dormant Herpes Could Be Reactivated By COVID-19 And Might Serve As An indicator Of Latent COVID 19 Infection. Varied Implications

BREAKING! COVID-19 News: Dormant Herpes Could Be Reactivated By COVID-19 And Might Serve As An indicator Of Latent COVID 19 Infection. Varied Implications
Sourec: COVID-19 News  Aug 03, 2020  3 years, 8 months, 2 weeks, 15 hours, 6 minutes ago
COVID-19 News: Numerous clinical reports are indicating that dormant Herpes Zoster and Herpes Simplex could be activated by the COVID-19 infections due to deterioration of systemic health and the immunity system. Some medical doctors and researchers are also suggesting that the manifestation of Herpes Zoster or Herpes Simplex could be an indication of a latent COVID-19 infection that has not been detected yet.


Herpes Zoster
 
Whatever the case could be there seems to be a growing association between the Herpes and COVID-19 and many questions are now being raised as to whether prior Herpes infections could also be a risk factor for contracting the COVID-19 disease.
 
In one of the earliest clinical report from researchers from Egypt that has also been noted in WHO’s records, various cutaneous manifestations have been observed in patients with COVID‐19 infection. Herpes zoster is a viral skin disease caused by varicella zoster that remains dormant in the dorsal root ganglia of cutaneous nerves following a primary chicken pox infection. In this report, the researchers describe two cases COVID infection who first presented with herpes zoster. They suggested that the clinical presentation of Herpes Zoster at the time of the current pandemic even in patients giving mild or no suggestive history of upper respiratory symptoms should be considered as an alarming sign for a recent subclinical SARS CoV2 infection. https://onlinelibrary.wiley.com/doi/full/10.1111/dth.13666 and https://pesquisa.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/en/covidwho-343270
 
In another clinical report by researchers from Italy, (https://onlinelibrary.wiley.com/doi/10.1111/ijd.15001) cutaneous manifestations in 4 severe COVID‐19‐positive patients indicated herpes zoster infections. The four cases retrieved, three female, one male, median age 70.5 years (range 68–74), three were admitted to the ICU and required mechanical ventilation along with hydroxychloroquine and tocilizumab administration in one patient. All three patients developed a necrotic herpes zoster on the second branch of the trigeminal nerve. The male patient featuring a cardiac transplant was treated with hydroxychloroquine and azithromycin and developed the disease on the dorsum with the classic herpes zoster features. Despite the transplant and the immunosuppressive drug used, the patient showed a more indolent COVID‐19 behavior and did not require hospitalization. The median time from COVID‐19 and herpes zoster diagnosis was 5.5 days. All patients at the time of zoster diagnosis showed leukopenia (lymphocyte count 0.57 109/l – normal value range 1.10–4.00 109/l). After diagnosis, acyclovir treatment was started at the standard dosage as well as analgesics.

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The Italian researchers said that little is known about the immunologic mechanisms which can determine severe disease or about skin‐related disorders.
 
More different groups reported patients featuring