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BREAKING NEWS
Source: Thailand Medical News  Jan 10, 2020  7 months ago
Individuals With Heart Disease Have Higher Risk Of Kidney Failure
Individuals With Heart Disease Have Higher Risk Of Kidney Failure
Source: Thailand Medical News  Jan 10, 2020  7 months ago
A new study indicates that cardiovascular diseases, including heart failure, atrial fibrillation, coronary heart disease, and stroke are each linked with a higher risk of developing kidney failure. The findings, which appear in an upcoming issue of JASN, highlight the importance of protecting the kidney health of individuals diagnosed with cardiovascular disease.



The kidneys and the heart have a bi-directional relationship, whereby dysfunction in either may compromise the function of the other. Many studies have investigated the risks of kidney disease on heart health, but few have examined the reciprocal relationship.

A medical research team led by Dr Kunihiro Matsushita, MD, Ph.D. and Dr Junichi Ishigami, MD, Ph.D. (Johns Hopkins Bloomberg School of Public Health) examined information on 9,047 US adults who did not have signs of heart disease when they enrolled in a community-based study.

Dr. Matsushita told Thailand Medical News via a phone interview,"Many physicians probably recognize that patients with cardiovascular disease are at risk of kidney disease progression, but to my knowledge, this is the first study quantifying the contribution of different cardiovascular diseases to the development of kidney failure."

In a median follow-up of 17.5 years, 2,598 participants were hospitalized with cardiovascular disease—1,269 with heart failure, 1,337 with atrial fibrillation, 696 with coronary heart disease, and 559 with stroke—and 210 patients developed kidney failure.

It was observed that the incidence of major cardiovascular disease was associated with a higher risk of kidney failure, with the highest risk for heart failure. Participants hospitalized with heart failure had an 11.4-times higher risk of developing kidney failure than participants without cardiovascular disease.

Dr. Ishigami told Thailand Medical News, "Individuals with a history of cardiovascular disease should be recognized as a high risk population for kidney failure. In this context, physicians should be aware of cardiovascular disease as an important risk condition, and thereby minimize treatments that are toxic to the kidneys in such individuals. Additionally, our findings may have implications for monitoring kidney function, although current cardiovascular disease guidelines do not necessarily specify the frequency of evaluating kidney f unction following the incidence of cardiovascular disease."

Reference: Incident Hospitalization with Major Cardiovascular Diseases and Subsequent Risk of ESKD: Implications for Cardiorenal Syndrome, Junichi Ishigami, Logan T. Cowan, Ryan T. Demmer, Morgan E. Grams, Pamela L. Lutsey, Juan-Jesus Carrero, Josef Coresh and Kunihiro Matsushita, JASN January 2020, ASN.2019060574; DOI: https://doi.org/10.1681/ASN.2019060574
 

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Source : Thailand Medical news
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