More HIV Patients dying from cryptococcal infections
Latest Worldwide figures show that 1 out of 10 HIV related deaths are due cryptococcal infections. .According to a study by Barcelona Institute for Global Health , the incidences of deaths due to the fungus is rising due to late detection and also because the fungus itself is mutating and presenting less obvious symptoms in the early stages of infection. Frequent CrAg screening and preemptive therapy is suggested.
Scientists discovers exact cause of Cachexia
Cachexia, the withering symptoms associated with cancer, autoimmune diseases, AIDs, Tuberculosis etc was used to be thought to be due to molecular processes associated with inflammatory responses and could not even be reversed with nutritional supplementation, might now have a new strategies to overcome it.
Researchers at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences have discovered that the loss of weight, depletion of fat cells and loss of appetite are all actually cause by a group of immune cells called CD8 T cells. These CD8 T Cells received signals from from the antiviral cytokine type I interferons or anticancer cytokines to initiate the process starting at cellular levels. This new insight may lead to innovative therapeutic strategies for cachexia and associated life-threatening chronic diseases.
New Protocol involving heart proteins may serve as indicators of heart disease risk.
Researchers at Baylor College Of Medicine have discovered through various studies that patients with elevated Troponin 1 levels along with Troponin T in their bloodstream were at high risk of cardiovascular disease and also fatalities. Previous protocols only involved troponin 1 but this dual biomarker approach was more accurate at isolating those that were at risk.
Scientists discover that lack of sleep gives rise to lack of Physiological Regulators, or
microRNAs being produced.
Scientists at the University of Colorado have discovered that anyone that sleeps less than 7 hours per day were most likely to have 40 to 60 percent lower circulating levels of miR-125A, miR-126, and miR-146a . These MicroRNAs are small molecules that suppress gene expression of certain proteins in cells and they have an effect on cardiovascular health and also in cancer onsets. These findings show that those with insufficient sleep might be at a higher risk for heart disease, stroke and even cancer.
Drug Dupilumab reduces exacerbations in late-onset asthma
Findings presented at the recent American Thoracic Society 2019 International Conference showed that the usage of the drug Dupilumab (Dupixent by Sanofi) was more efficient in treating patients that had late-onset asthma compared with any other existing drugs.
Enzymes that can prevent Diabetic Kidney Disease discovered
Scientists from Joslin Diabetes Center have discovered a type of enzyme involved in glucose metabolism that can prevent kidney complications in diabetic patients. The enzyme known as PKM2, plays a strong protective role against kidney disease. This enzymes could be used as both a biomarker and target for DKD intervention.
Cancer Drugs to be repurposed to treat brain aneurysms
Researchers from the University of Sussex have made headway studies into the cause of brain aneurysms and have also discovered that a current class of cancer drugs known as receptor tyrosine kinase inhibitors can be used to treat the condition. Plans are already underway to get the US FDA approvals for repurposing the drug
All news compiled by Thailand Medical News