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Source: COVID-19-Thyroid Gland   Mar 22, 2021  3 years, 3 weeks, 5 days, 18 hours, 45 minutes ago

Italian Study Presented At Endocrine Society's 2021 Annual Meeting Shows That SARS-CoV-2 Causes A Unique Thyroid Inflammation In Some Patients.

Italian Study Presented At Endocrine Society's 2021 Annual Meeting Shows That SARS-CoV-2 Causes A Unique Thyroid Inflammation In Some Patients.
Source: COVID-19-Thyroid Gland   Mar 22, 2021  3 years, 3 weeks, 5 days, 18 hours, 45 minutes ago
A new study presented in the last 24 hours at the Endocrine Society's 2021 Annual Meeting (ENDO 2021) by researchers from Fondazione IRCCS Ca' Granda Policlinico Hospital of Milan and the University of Milan in Italy has indicated that certain patients with moderate to severe COVID-19 disease seem to experience inflammation of the thyroid gland that is different from thyroid inflammation caused by other viruses.


 
Alarmingly one-third of the study participants still had signs of thyroid inflammation after three months, even though their thyroid function had normalized.
 
The research team is also following patients to determine whether this inflammation will trigger permanent thyroid dysfunction.
 
It was found that in spring 2020, 15 percent of the COVID-19 patients hospitalized in acute medicine units at Fondazione IRCCS Ca' Granda Policlinico Hospital of Milan in Italy had thyroid hormone alterations due to multi-factorial causes, including thyroid inflammation. In comparison, only 1 percent of hospitalized patients during the same period in 2019 prior to the pandemic had thyroid hormone alterations.
 
Lead researcher Dr Ilaria Muller, M.D., Ph.D. from the University of Milan in Italy told Thailand Medical News, “Typically individuals with thyroiditis, or inflammation of the thyroid gland, triggered by other viruses usually recover thyroid function in the short term. However, there is a long-term increased risk of permanently reduced thyroid function, caused by late-onset effects of viral infection, or by the immune system attacking the thyroid gland.”
 
Dr Muller wanted to find out whether the thyroiditis associated with SARS-CoV-2, the virus that causes COVID-19 disease, follows the same pattern as thyroid inflammation caused by other viruses.
 
The study team started a surveillance program to monitor the thyroid function of patients every three months after being hospitalized for moderate to severe COVID-19 disease. The patients undergo routine blood and ultrasound testing to monitor their thyroid function and signs of inflammation.

Dr Muller found the thyroiditis in people with moderate to severe COVID-19 disease differs from typical thyroiditis in several ways. These include the absence of neck pain, the presence of mild thyroid dysfunction, higher frequency among men and the association with severe COVID-19 disease.
 
To date all 53 patients have completed the evaluation at three months. All had normal thyroid function.
 
Dr Muller added, "After three months, patients' thyroid function has normalized, but signs of inflammation were still present in about one-third of patients. We are continuing to monitor these patients to see what happens during the following months. It is important to know whether SARS-CoV-2 virus has late-onset negative effects on the thyroid gland, in order to promptly diagnose, and ev