In Memory Of My Beloved Mother, Mrs Raj Prasad Who Passed Away In Singapore At 0050 Hrs 6th October 2022

Source: COVID-19 Clinical Care  May 05, 2020  2 years ago
COVID-19 Clinical Care: Latest Guidelines For Managing Critical COVID-19 Patients
COVID-19 Clinical Care: Latest Guidelines For Managing Critical COVID-19 Patients
Source: COVID-19 Clinical Care  May 05, 2020  2 years ago
COVID-19 Clinical Care: The American Society for Artificial Internal Organs (ASAIO) has released a set of recommendations for health care workers on the front lines, to help them make decisions on how to treat the most critical COVID-19 patients especially those with severe lung or heart failure

Lead author Dr Keshava Rajagopal, a Professor of clinical sciences at the University of Houston College of Medicine told Thailand Medical News, "An urgent need exists to enhance our understanding of the roles of extracorporeal membrane oxygenation (ECMO) and other types of artificial lung and heart support in the management of severely ill patients with COVID-19 who develop acute respiratory, and less commonly cardiac, compromise untreatable by conventional therapy."
Dr Faisal Cheema, an Associate Professor of clinical sciences, is a co-author on the research paper which is published in the ASAIO Journal.

Typically, ECMO circuits contain a pump and a gas exchanger and can be used to support the lungs and/or heart, depending upon the way in which the circuitry is connected to a patient.
As a result of the COVID-19 pandemic emerging and spreading so quickly, clinical unknowns exist of when to apply such drastic measures.
Dr Rajagopal added, "It is not known when it is clinically appropriate to use the most advanced forms of lung and heart support for COVID-related respiratory and heart failure and so we discuss this in terms of non-COVID usage, these decisions are critical in a resource-scarce environment.”
It has been observed that the more advanced the therapy, generally the less of it exists in supply. How to deploy the scarcest of resources under pandemic circumstances is not well defined. The new guidelines recommend that a critical consideration in deciding when to deploy ECMO and other types of artificial lung/heart support, and even lesser therapies such as mechanical ventilation, is to assess whether the patient has a good likelihood of recovery.
Dr Rajagopal further added, "In a pandemic we have to decide how to allocate limited resources, and the first two questions that need to be asked are: One, is the patient sick enough to warrant the therapy, and two, is the patient well enough to tolerate the risks of the therapy? Next, we have to determine if the supply of the resource sufficient at the given time. We need to compare what could happen with the most advanced therapies, supply wise, to what has already happened with ventilators in some hospitals.”
The researcher’s recommendations call for non-invasive therapies first, such as continuous positive airway pressure (CPAP) and bilevel positive airway pressure (BiPAP) for short durations. Once a patient fails these and requires invasive mechanical ventilation (MV), then other recommendations are:
1) Whenever possible, all patients with severe hypoxemic respiratory failure with COVID-19 ARDS should undergo either manua l or artificial prone-positioning, depending upon the resources available.
2) Protocol such as Lung-protective mechanical ventilation (MV) should be used in patients with COVID-19-related acute hypoxemic respiratory failure.
3) The physician’s decision to implement ECMO should follow a clear failure of invasive MV, paralytic agents and prone positioning.
As there is little that has been written about the protocol doctors must take when treating the serious or critical COVID-19 patients, the recommendations will be updated.
Dr Rajagopal added, "We call this a living, working document because we are still getting information and we intend to republish a final version and second paper once we have more experience from around the world.”
For more updates on COVID-19 Clinical Care, keep logging to Thailand Medical News.
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