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Source: Thailand Medical News  May 25, 2019  3 years ago
Summarised Updates About Latest Developments On Prostate Cancer.
Summarised Updates About Latest Developments On Prostate Cancer.
Source: Thailand Medical News  May 25, 2019  3 years ago
There are more than 1.1 million new cases of men diagnosed with Prostate Cancer each year while about 310,000 of them die annually due to the disease. (Figures from Globoscan). Here Thailand Medical News brings you in summarized form, developments this week from across the globe with regards to prostate cancer research and developments for easy reading.


 
 
Biomaker, PSA contributes to cancer spread and metastasis
Researchers from the University Of Helsinki has discovered that PSA that is a biomarker for Prostate cancer , activates the vascular endothelial and lymphangiogenic growth factors VEGF-C and VEGF-D. These growth factors play a central role not only in fetal development but in the spread of cancer and the formation of metastases. Finding a way to inhibit this catalytic mechanism of PSA might lead to the discovery of new novel drugs.
 
 
Abiraterone provides better HRQoL than Enzalutamide for mCRPC
A clinical trial in Europe involving 202 patients suffering from metastatic castration-resistant prostate cancer (mCRPC), found that Treatment with abiraterone leads to fewer health-related quality of life (HRQoL) and mental health issues than enzalutamide . Both drugs are the approved drugs currently to treat mCRPC.
 
 
Molecule Drug, discovered that can inhibit oncoprotein production in Prostate Cancer
A molecule drug called MKC8866 has been discovered by scientist at University Of Oslo that can inhibit certain signaling pathways that leads to the prostate cancer tumors and also the production of oncoproteins. It will take years of further research and clinical trials before it is actually available for treatment.
 
 
Saturated fatty acids contribute to progression of Prostate cancer
Doctors at Monash and Melbourne University have discovered that a diet in saturated fatty acids contribute to Prostate cancer incidences and also progression of the disease whereas  using blockers to control saturated fatty acid intakes actually help in the treatment process of prostate cancer . These findings identify a critical role for CD36-mediated fatty acid uptake in prostate cancer and suggest that targeting fatty acid uptake might be an effective strategy for treating prostate cancer .  (CD36 is a fatty acid transporter in the cellular level.)
 
 
Chemicals in Coffee may slow prostate cancer growth
Scientists from Kanazawa University, Japan and from University Of Barcelona have identified two compounds found in Arabica Coffee called kahweol acetate and cafestol that in various laboratory research, have showed to slow the growth of prostate cancer cells. These new findings carry lots of implications and more research is currently underway.
 
 

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