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Source: Strokes And COVID-19  Sep 19, 2020  3 years, 7 months, 55 minutes ago

Strokes And COVID-19: Study By University Of Alabama Shows That Stroke Victims With COVID-19 Have Increased Inflammation, Severity And Death

Strokes And COVID-19: Study By University Of Alabama Shows That Stroke Victims With COVID-19 Have Increased Inflammation, Severity And Death
Source: Strokes And COVID-19  Sep 19, 2020  3 years, 7 months, 55 minutes ago
Strokes And COVID-19: According to a new study from University of Alabama at Birmingham led by Dr Chen Lin, M.D., an assistant professor in the Department of Neurology, stroke patients who also have COVID-19 showed increased systemic inflammation, a more serious stroke severity and a much higher rate of death, compared to stroke patients who did not have COVID-19.


 
The new study finding comes about at a time where the global incidence of strokes is rising drastically over the last few months with more younger adults also being affected by the condition. A possible hypothesis is that COVID-19 is also exacerbating the incidence of strokes.
 
The study was published in the journal Brain, Behavior & Immunity-Health
https://www.sciencedirect.com/science/article/pii/S2666354620301022?via%3Dihub
 
The study is a retrospective, observational, cross-sectional study of 60 ischemic stroke patients admitted to UAB Hospital between late March and early May 2020. Ischemic stroke occurs when a blood vessel for the brain is blocked by a clot, depriving some brain tissue of oxygen. All patients were tested for COVID-19 at admission.
 
The study team mined electronic medical records of confirmed stroke cases for information on age, gender and race; clinical variables; laboratory data, including complete blood counts, blood chemistry and coagulation tests; and outcomes, including death, length of hospital stay and condition at discharge.
 
Importantly, the ratio of the number of neutrophils to the number of lymphocytes, or the NLR, as calculated from blood count data, served as an index of the systemic inflammatory response.
 
Although other medical experts and researchers have associated NLR with COVID-19 disease severity, refractory disease and even as an independent factor for mortality, "our research is the first to associate the NLR in patients with COVID-19 and ischemic stroke and stroke severity," Dr Lin said.
 
It was observed that of the 60 hospitalized patients with acute systemic stroke, nine