Cardiac or heart
problems are a common development for people with diabetes
. In fact, about 35% of people globally are admitted to the hospital for heart failure
also have diabetes
. Heart failure
may be the result of a co-condition, such as hypertension or coronary heart
disease, but not always.
A new study published in Mayo Clinic Proceedings
Mellitus Is an Independent Predictor for the Development of Heart Failure
: A Population Study, examines the idea of diabetic cardiomyopathy
and heart failure
from the effects of diabetes
Using the Rochester Epidemiology Project, researchers evaluated the long-term impact of diabetes
on the development of heart failure
, both with preserved ejection fraction a measurement of the percentage of blood leaving the heart
with each contraction and reduced ejection fraction. They also looked at mortality in a community population, controlling for hypertension, coronary artery disease and diastolic function. Dr Horng Chen, M.D., cardiologist at Mayo Clinic in Rochester, Minnesota, is senior author of the study.
For the study, an initial group of 2,042 residents of Olmsted County, 116 study participants with diabetes
were matched 1:2 for age, hypertension, sex, coronary artery disease and diastolic dysfunction to 232 participants without diabetes
. Over the 10-year follow-up period, 21% of participants with diabetes
developed heart failure
, independent of other causes. In comparison, only 12% of patients without diabetes
developed heart failure
. Cardiac death, heart
attack and stroke were not statistically different in the study between the two groups.
The research findings show that diabetes
is an independent risk factor for the development of heart failure
in the community dwelling population. Furthermore, the outcome data support the concept of a diabetic cardiomyopathy
This new research extends previous findings and demonstrates that even without a known cardiac structural abnormality and with a normal ejection fraction, diabetic
patients are still at increased risk of developing heart failure
as compared to their nondiabetic counterparts.
Dr. Chen told Thailand Medical
news, "The key takeaway is that diabetes
mellitus alone is an independent risk factor for the development of heart failure
. Our hope is that this study provides a strong foundation for further investigations into diabetes and heart failure
rong>. There is still much to learn and study in terms of this association and how to best diagnose and treat this condition."
Reference : Diabetes Mellitus Is an Independent Predictor for the Development of Heart Failure, Michael D. Klajda, MD, Christopher G. Scott, MS, Richard J. Rodeheffer, MD, Horng H. Chen, MB BCh, Mayo Clinic Proceedings DOI: https://doi.org/10.1016/j.mayocp.2019.07.008