Morons Across the World Hyper Reacting To Omicron! The Reality Is That There Are So many Other Worrisome Variants Already Emerging Or Will Emerge Shortly!
It was fun to see the type of reactions taking place in the last 48 hours over the identification of the Omicron or B.1.1.529 variant that has a total of 59 mutations found on it including 32 on its spike proteins.
Despite the vast number of mutations on its genome and the fact that it is still stable, there is no real need to get alarmed and panic as the reality of the situation is that mankind has already really lost the war against the SARS-CoV-2 coronavirus due to the Western world over emphasis of antibody based therapeutics from convalescent plasma, monoclonal and polyclonal drugs to vaccines. All these have helped contribute to the rise of variants along with the kinetics of the numbers of vaccinated against the unvaccinated over periods of time. https://www.thailandmedical.news/news/university-of-cambridge-study-shows-neutralizing-antibodies-are-driving-mutations-of-spike-mediated-sars-cov-2-evasion-including-in-b-1-1-7-variant
Human genes and mutations, medical conditions and status of the immune system are all also factors driving mutations and the rise of new variants not to forget the zoonotic and reverse zoonotic transmissions of the SARS-CoV-2 to various animals and back to humans again. https://www.nature.com/articles/s41467-021-27096-9
The B.1.1.529 is not the only unique variant that has the potential for higher transmissibility and immune evasiveness. There are now almost hundreds of such variants including so many Delta sub-variants such as the AY.104 that is just as worrying or the non-Delta variant B.1.640. https://www.thailandmedical.news/news/breaking-new-worrisome-delta-sub-variant-found-in-sri-lanka-ay-104-could-be-more-transmissible-than-ay-4-2-and-more-virulent-and-immune-evasive
The number of mutations found on a variant is not as important as to the quality of the mutation and what it is capable of achieving.
Already experts are sounding alarms that there are so many new variants emerging that cannot even be detected by current PCR tests or ATK test kits. https://www.thailandmedical.news/news/breaking-expert-from-london-medical-laboratory-warns-that-standard-covid-19-pcr-test-does-not-pick-up-new-sars-cov-2-strains-and-variants
Simply banning flights to and from the various African countries to prevent the spread of the B.1.1.529 or Omicron variant is not going to help.
The world has to sacrifice the air travel, hotel and tourism industries for a while and impose total border controls and all flight bans for at least a year in order to solve the mess that we are in alongside with proper and accurate mass testing, proper isolations and proper therapeutics.
Banking on simply the two coming antiviral drugs will also be another major disaster waiting to happen. In fact, we at Thailand Medical News cannot wait for the Merck’s toxic and mutagenic drug Molnupiravir to get approved and used in the western countries like America and Britain first as it will be fun to see the consequences both short and long term. https://www.forbes.com/sites/williamhaseltine/2021/11/01/supercharging-new-viral-variants-the-dangers-of-molnupiravir-part-1/?sh=67a0525a6b15
There will be so many new clinical conditions and manifestations in coming months associated with Long COVID and cancers will also start to become more apparent as a ‘by product’ of the COVID-19 disease. https://www.thailandmedical.news/news/breaking-new-international-study-warns-that-sars-cov-2-infections-will-lead-to-cancers-especially-colorectal-cancers-due-to-disruption-in-autophagy
In 2022, the buzzwords will be re-infections, co-infections, recombinant variants, cancers, neurological issues, heart failures and kidney failure coupled with a wide range of gastrointestinal conditions.
COVID-19 death rates and excess death rates will continue to climb but gradually till about mid 2023 when we will start to see real spike in death rates caused as a result of viral priming.
Already there are signs that some of the SARS-CoV-2 variants are evolving to become more or less an enteric virus besides already being a respiratory virus. https://journals.sagepub.com/doi/full/10.1177/1178636121999673
Despite whatever that is being said, the genomic surveillance of SARS-CoV-2 is extremely weak and even in the case of the Omicron variant which was only officially identified on the 11th
of November, it could have already been in circulation for weeks earlier to that and is currently already in many countries with local health authorities aka buffoons not even being aware of it.
With millions of HIV patients and other kinds of immunocompromised individual across the world, such variants like the Omicron are constantly going to appear along with the other factors mentioned earlier contributing to their rise.
The only solution to the COVID-19 crisis is the development of a range of antiviral combinations along with stringent border controls and flight bans, stringent testing and isolation etc.
Failure to adopt such a drastic approach, will only see the pandemic prolonging for years with more nasty consequences as time proceeds.
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