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Nikhil Prasad  Fact checked by:Thailand Medical News Team Jan 03, 2024  1 month, 2 weeks, 4 days, 10 hours, 10 minutes ago

COVID-19 News: Despite 1 Out of 24 Currently Infected, Experts Warn That JN.1 Surge In United Kingdom Has Yet To Peak And That Infections Will Still Rise!

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COVID-19 News: Despite 1 Out of 24 Currently Infected, Experts Warn That JN.1 Surge In United Kingdom Has Yet To Peak And That Infections Will Still Rise!
Nikhil Prasad  Fact checked by:Thailand Medical News Team Jan 03, 2024  1 month, 2 weeks, 4 days, 10 hours, 10 minutes ago
COVID-19 News: In the face of an unrelenting surge in COVID-19 cases, the United Kingdom finds itself grappling with a formidable opponent - the JN.1 variant. Contrary to initial expectations of a peak, infections are skyrocketing, and concerns are mounting over the trajectory of this wave. Scientists are sounding the alarm as the JN.1 variant, a descendant of the Ba.2.86 variant, gains prominence, surpassing 45% of all COVID cases on Christmas Day.
https://cov-spectrum.org/explore/United%20Kingdom/AllSamples/Past6M/variants?nextcladePangoLineage=jn.1*&
 


This 'immune evasive' variant is proving to be a significant threat, prompting experts to caution that the current wave has not yet peaked, and infections are anticipated to rise for several weeks.
 
The Ascendance of JN.1: From Inception to Dominance
The JN.1 variant has emerged as a force to be reckoned with, displaying a concerning trajectory since its inception. Initially constituting a mere 1% of coronavirus cases in late October, it swiftly climbed to 5% by mid-November. However, the most alarming development came to light on Christmas Day when JN.1 reached a staggering 45%, dethroning other variants and establishing itself as the dominant strain.
 
Professor Christina Pagel from University College London warns that the rapid growth of JN.1 could propel the UK towards its highest infection rate ever, potentially surpassing even the Omicron waves that characterized 2022.This a was covered in various UK COVID-19 News coverages:
 
https://inews.co.uk/news/covid-cases-break-uk-record-january-jn1-variant-2833317
 
https://www.mirror.co.uk/news/uk-news/covid-cases-yet-peak-infections-31792683
 
https://www.msn.com/en-gb/health/other/covid-cases-may-break-uk-record-in-january-due-to-jn-1-variant-scientists-warn/ar-AA1mmc3C
 
Forecasting the Course: Drawing Parallels with Omicron Substrains
To comprehend the potential severity of the JN.1 wave, experts are drawing parallels with previous Omicron waves, particularly BA.1 in December 2021 and BA.5 in January 2022. Notably, these substrains reached their peaks three weeks after surpassing 45% of all COVID cases. Professor Pagel suggests that the JN.1 wave is likely to peak in mid-January, with high infection rates expected to persist for several weeks on the downward slope. Although hospitalization levels are not anticipated to reach the heights witnessed during previous Omicron waves, concerns loom about case numbers resembling the record-setting BA.2 wave in March and April 2022.

Waning Immu nity: A Looming Challenge
Beyond the surge in cases, scientists are expressing grave concerns about the phenomenon of waning immunity. Professor Peter Openshaw from Imperial College London emphasizes the natural decline in immunity over time, especially for individuals who have not received booster shots in over a year. This raises crucial questions about the potential impact of waning immunity on the severity and duration of the ongoing wave. As the JN.1 variant asserts its dominance, understanding and addressing issues related to immunity become paramount in the battle against the evolving threat.
 
Global Perspectives: CDC's Assessment and UKHSA's Findings
Beyond the shores of the United Kingdom, global health authorities are closely monitoring the situation. The U.S. Center for Disease Prevention and Control (CDC) acknowledges the rapid spread of JN.1 but asserts that, at present, there is no evidence suggesting an increased risk compared to other circulating variants.
https://www.cdc.gov/respiratory-viruses/whats-new/SARS-CoV-2-variant-JN.1.html
 
Despite this, the U.S. CDC remains vigilant, emphasizing the importance of ongoing surveillance and research to assess the full implications of the JN.1 variant.
 
Meanwhile, the UK Health Security Agency's (UKHSA) and UK NHS latest reports provides a snapshot of the COVID-19 prevalence, estimating it at 4.2% across the total population in England and Scotland. This statistic implies that approximately 1 in every 24 people could test positive for any type of COVID infection at the current time. The prevalence rates are notably higher among individuals aged 18 to 44, with the region of London experiencing the highest prevalence.
https://www.england.nhs.uk/london/2023/12/28/advice-to-londoners-as-covid-and-flu-cases-rise/
 
https://www.gov.uk/government/statistics/winter-coronavirus-covid-19-infection-study-estimates-of-epidemiological-characteristics-england-and-scotland-2023-to-2024/winter-coronavirus-covid-19-infection-study-estimates-of-epidemiological-characteristics-21-december-2023
 
Seasonal Factors Amplifying the Surge
The surge in cases is not occurring in isolation but is exacerbated by seasonal factors. The cold winter weather, coupled with increased socializing indoors during the holiday season, has contributed to the spike in infections. The National Health Service (NHS) and UKHSA are urgently appealing to all eligible individuals to avail themselves of the seasonal COVID-19 vaccine before the window closes on January 31, 2024. Professor Steven Riley, Director General for Data and Surveillance at UKHSA, emphasizes that the combination of cold weather, shorter days, and heightened social interactions amplifies the potential for transmission of respiratory viruses like COVID-19. As the country navigates through this challenging period, the importance of vaccination and adherence to public health guidelines cannot be overstated.
 
Conclusion:
The evolving situation in the United Kingdom, marked by the ascent of the JN.1 variant, underscores the complex nature of the ongoing battle against COVID-19. As the nation faces the challenges posed by this immune-evasive variant, proactive measures, including vaccination campaigns and stringent public health precautions, become paramount. The coming weeks are poised to be critical in determining the trajectory of the JN.1 surge and its impact on the healthcare system, highlighting the need for a united and coordinated response to safeguard public health. In this ever-evolving landscape, global collaboration, ongoing research, and a commitment to public health measures remain pivotal in navigating the complexities of the COVID-19 pandemic.
 
For the latest COVID-19 News, keep on logging to Thailand Medical News.

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