COVID-19 And HIV
: Individuals with HIV who were hospitalized with COVID-19 did not have worse results than COVID-19 patients without HIV, according to new research by Icahn School of Medicine at Mount Sinai.
The research findings were published in the journal: Clinical Infectious Diseases https://academic.oup.com/cid/article/doi/10.1093/cid/ciaa880/5864410?searchresult=1
Study author Dr. Keith Sigel, a member of the Mount Sinai COVID Informatics Center at the Icahn School of Medicine at Mount Sinai, in New York City told Thailand Medical News, "Throughout the pandemic, we've suspected that immunocompromised patients, such as those with HIV, could be at a higher risk for infection and suffer more severe outcomes, but without data on how COVID-19 affects patients with HIV specifically, clinical guidance for managing and advising these patients has been lacking."
Individuals with a weakened immune system often have worse outcomes when they develop serious infections. HIV is one of the most common causes of immunodeficiency in the world and affects more than one million people in the United States.
Researchers compared COVID-19 patients with and without HIV for the study at five hospitals in the Mount Sinai Health System in New York City. The patients were assessed at the peak of the pandemic in the city during March and April.
Although death rates and poor outcomes such as respiratory failure or multi-organ dysfunction were high among patients with HIV, but no worse than among those without HIV, the researchers found.
Also the patients with HIV did not have evidence of significant immune suppression or elevated HIV viral levels.
This sresearch adds to existing limited evidence that HIV may not be associated with more severe COVID-19 symptoms, the researchers said.
Dr Sigel added, "This study sets the foundation for future studies in larger cohorts so we can appropriately address treating COVID-19 in patients with HIV.”
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