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Source: SARS-CoV-2-Brain  Oct 21, 2021  2 years, 5 months, 4 weeks, 18 hours, 53 minutes ago

Saudi Arabia MRI Study Provide Further Evidence That SARS-CoV-2 Affects The Brain With 57.9% Of Severe COVID-19 Patients Having Brain Lesions!

Saudi Arabia MRI Study Provide Further Evidence That SARS-CoV-2 Affects The Brain With 57.9% Of Severe COVID-19 Patients Having Brain Lesions!
Source: SARS-CoV-2-Brain  Oct 21, 2021  2 years, 5 months, 4 weeks, 18 hours, 53 minutes ago
SARS-CoV-2-Brain: A new MRI study by researchers from Saudi Arabia suggests pneumonia in COVID-19 patients is linked to viral-induced changes in the brain. MRI scans revealed that 57.9% of severe SARS-CoV-2 infected patients had recent brain lesions! The study findings provide further evidence that SAR-CoV-2 affects the brain and causes brain lesions and also generates various neurological manifestations.

 
According to the study abstract, “The increased frequency of neurological manifestations, including central nervous system (CNS) manifestations, in patients with COVID-19 is consistent with the virus's neurotropic nature. In most patients, brain magnetic resonance imaging (MRI) is a sensitive imaging modality in the diagnosis of viral encephalitides in the brain.”
 
The study team’s objectives were to determine the frequency of brain lesion patterns on brain MRI in SARS-CoV-2 pneumonia patients who developed focal and non-focal neurological manifestations. In addition, the stud was to compare the impact of the Glasgow Coma Scale (GCS) as an index of deteriorating cerebral function on positive brain MRIs in both neurological manifestations.
 
This retrospective study included an examination of SARS-CoV-2 pneumonia patients with real-time reverse transcription polymerase chain reaction (RT-PCR) confirmation, admitted with clinicoradiologic evidence of COVID-19 pneumonia, and who were candidates for brain MRI due to neurological manifestations suggesting brain involvement. Brain imaging was acquired on a 3.0 T MRI system (Skyra; Siemens, Erlangen, Germany) with a 20-channel receive head coil.
 
Brain MRI revealed lesions in 38 (82.6%) of the total 46 patients for analysis and was negative in the remaining eight (17.4%) of all finally enclosed patients with RT-PCR confirmed SARS-CoV-2 pneumonia. Twenty-nine (63%) patients had focal neurological manifestations, while the remaining 17 (37%) patients had non-focal neurological manifestations. The patients had a highly significant difference (p = 0.0006) in GCS, but no significant difference (p = 0.4) in the number of comorbidities they had.
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